Time course of HF16 hairpin ribozyme-catalyzed cleavage of unmodified (circles), 2′-NH-modified (squares) and photo-crosslinker -modified (triangles) substrate

Abstract

<p><b>Copyright information:</b></p><p>Taken from "Investigation of Mg- and temperature-dependent folding of the hairpin ribozyme by photo-crosslinking: effects of photo-crosslinker tether length and chemistry"</p><p>Nucleic Acids Research 2005;33(3):1058-1068.</p><p>Published online 18 Feb 2005</p><p>PMCID:PMC549404.</p><p>© The Author 2005. Published by Oxford University Press. All rights reserved</p> Insert shows an expansion of early time points. SD values were 2, 2, 3 and 4% for 2′-NH-modified HF16 activity and 0.4, 2, 3 and 1% for -modified HF16 activity at 0.5, 1, 30 and 120 min, respectively