4,644 research outputs found
Information-Matter Bipolarity of the Human Organism and Its Fundamental Circuits: From Philosophy to Physics/Neurosciences-Based Modeling
Starting from a philosophical perspective, which states that the living structures are actually a combination between matter and information, this article presents the results on an analysis of the bipolar information-matter structure of
the human organism, distinguishing three fundamental circuits for its survival, which demonstrates and supports
this statement, as a base for further development of the informational model of consciousness to a general
informational model of the human organism. For this, it was examined the Informational System of the Human Body and its components from the perspective of the physics/information/neurosciences concepts, showing specific
functions of each of them, highlighting the correspondence of these centers with brain support areas and with their projections in consciousness, which are: Center of Acquisition and Storing of Information (CASI) reflected in
consciousness as memory, Center of Decision and Command (CDC) (decision), Info-Emotional Center (IES)
(emotions), Maintenance Informational System (MIS) (personal status), Genetic Transmission System (GTS)
(associativity/genetic transmission) and Info Genetic Generator (IGG) related by the body development and
inherited behaviors. The Info Connection (IC), detected in consciousness as trust and confidence can explain the Near-Death Experiences (NDEs) and associated phenomena. This connection is antientropic and informational, because from the multitude of uncertain possibilities is selected a certain one, helping/supporting the survival and
life. The human body appears therefore as a bipolar structure, connected to two poles: information and matter. It is argued that the survival, which is the main objective of the organism, is complied in three main ways, by means of: (i) the reactive operation for adaptation by attitude; (ii) the info-genetic integration of information by epigenetic processes and genetic transmission of information for species survival, both circuits (i) and (ii) being associated to
the information pole; (iii) maintenance of the material body (defined as informed matter) and its functions, associated to the matter pole of the organism. It results therefore that the informational system of the human body is
supported by seven informational circuits formed by the neuro-connections between the specific zones of the brain
corresponding to the informational subsystems, the cognitive centers, the sensors, transducers and execution
(motor/mobile) elements. The fundamental informational circuits assuring the survival are the reactive circuit, expressible by attitude, the epigenetic/genetic circuit, absorbing and codifying information to be transmitted to the next generations, and the metabolic circuit, connected to matter (matter pole). The presented analysis allows to
extend the informational modeling of consciousness to an Informational Model of Consciousness and Organism, fully describing the composition/functions of the organism in terms of information/matter and neurosciences concep
An Information Based Model of Consciousness Fully Explaining the Mind Normal/Paranormal Properties
ABSTRACT
The main informational components of consciousness are described as Operative Informational System (OIS)
assuring the reactive short-time adaptation and Programmed Informational System (PIS), assuring the life
maintenance and the species survival, working in an integrated manner with the informed matter IM (body). The
defined informational subsystems allow to describe consciousness as a sum of cognition centers defined by Ibelieve,
Iknow, Iwant, Ilove, Iam, Icreate and Icreated. The cognition center Ibelieve was defined as related with the anti-entropic field
of the bipolar universal matter/antimatter informational system, assisting the life structuring and health and
explaining the precognition, psychokinesis, near-death experiences and other "paranormal" phenomena. PIS
related activity of the cognition centers was described as the projected data in OIS by two components: (1)
personal status as survival needs; (2) the info-consequences on oneself perception and action impulses perceived
by Iam, Icreate and Icreated, reflecting together with Iknow, Iwant and Ilove the "normal" (regular) mind properties
Genetics and Economic Mobility
Presents a literature review on the link between genetic traits, such as cognitive skills, health, mental health, personality, and appearance, and academic and economic success. Discusses how the environment influences how those traits affect mobility
The acheulean handaxe : More like a bird's song than a beatles' tune?
© 2016 Wiley Periodicals, Inc. KV is supported by the Netherlands Organization for Scientific Research. MC is supported by the Canada Research Chairs Program, the Social Sciences and Humanities Research of Canada, the Canada Foundation for Innovation, the British Columbia Knowledge Development Fund, and Simon Fraser UniversityPeer reviewedPublisher PD
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Non-Genetic Transmission of Obesity - It's in Your Epigenes.
Obesity and its related metabolic comorbidities can be inherited across generations through non-genetic mechanisms. In a recent report, Huypens et al., using an in vitro fertilization approach, provide evidence that exposure to a high-fat diet modifies egg and sperm epigenetic information, rendering the progeny more prone to obesity.Our research is supported by the MRC (MC_UU_12012/4) and the British Heart Foundation (FS/12/64/30001 and PG/14/20/30769).This is the author accepted manuscript. It is currently under an indefinite embargo pending publication by Elsevier
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Natural selection favoring more transmissible HIV detected in United States molecular transmission network.
HIV molecular epidemiology can identify clusters of individuals with elevated rates of HIV transmission. These variable transmission rates are primarily driven by host risk behavior; however, the effect of viral traits on variable transmission rates is poorly understood. Viral load, the concentration of HIV in blood, is a heritable viral trait that influences HIV infectiousness and disease progression. Here, we reconstruct HIV genetic transmission clusters using data from the United States National HIV Surveillance System and report that viruses in clusters, inferred to be frequently transmitted, have higher viral loads at diagnosis. Further, viral load is higher in people in larger clusters and with increased network connectivity, suggesting that HIV in the United States is experiencing natural selection to be more infectious and virulent. We also observe a concurrent increase in viral load at diagnosis over the last decade. This evolutionary trajectory may be slowed by prevention strategies prioritized toward rapidly growing transmission clusters
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HIV transmission networks among transgender women in Los Angeles County, CA, USA: a phylogenetic analysis of surveillance data.
BackgroundTransgender women are among the groups at highest risk for HIV infection, with a prevalence of 27·7% in the USA; and despite this known high risk, undiagnosed infection is common in this population. We set out to identify transgender women and their partners in a molecular transmission network to prioritise public health activities.MethodsSince 2006, HIV protease and reverse transcriptase gene (pol) sequences from drug resistance testing have been reported to the Los Angeles County Department of Public Health and linked to demographic data, gender, and HIV transmission risk factor data for each case in the enhanced HIV/AIDS Reporting System. We reconstructed a molecular transmission network by use of HIV-TRAnsmission Cluster Engine (with a pairwise genetic distance threshold of 0·015 substitutions per site) from the earliest pol sequences from 22â398 unique individuals, including 412 (2%) self-identified transgender women. We examined the possible predictors of clustering with multivariate logistic regression. We characterised the genetically linked partners of transgender women and calculated assortativity (the tendency for people to link to other people with the same attributes) for each transmission risk group.Findings8133 (36·3%) of 22â398 individuals clustered in the network across 1722 molecular transmission clusters. Transgender women who indicated a sexual risk factor clustered at the highest frequency in the network, with 147 (43%) of 345 being linked to at least one other person (adjusted odds ratio [aOR] 2·0, p=0·0002). Transgender women were assortative in the network (assortativity 0·06, p<0·001), indicating that they tended to link to other transgender women. Transgender women were more likely than expected to link to other transgender women (OR 4·65, p<0·001) and cisgender men who did not identify as men who have sex with men (MSM; OR 1·53, p<0·001). Transgender women were less likely than expected to link to MSM (OR 0·75, p<0·001), despite the high prevalence of HIV among MSM. Transgender women were distributed across 126 clusters, and cisgender individuals linked to one transgender woman were 9·2 times more likely to link to a second transgender woman than other individuals in the surveillance database. Reconstruction of the transmission network is limited by sample availability, but sequences were available for more than 40% of diagnoses.InterpretationClustering of transgender women and the observed tendency for linkage with cisgender men who did not identify as MSM, shows the potential to use molecular epidemiology both to identify clusters that are likely to include undiagnosed transgender women with HIV and to improve the targeting of public health prevention and treatment services to transgender women.FundingCalifornia HIV and AIDS Research Program and National Institutes of Health-National Institute of Allergy and Infectious Diseases
Consciousness as information system of the human body
Starting from the observation of the binary character YES/NOT of our decisions in
relation to the information received from the environment, determining both our life and specie
evolution by adaptation, it is defined the info-creational field and thought as an information
operator on this field, allowing to describe the individual EGO as a receiver and producer
information system, based on an operational and a programmed informational subsystem.
Consciousness appears thus be an integrated information system which allows the adaptation to
the environment and survival of specie, supported by informed matter (physical body) to
maintain functionality of the whole. On this basis, there were identified two main informational
circuits of the human body controlled by the consciousness: (i) the attitude as a short-time
reaction circuit allowing the immediate adaptation to the environment; (ii) the informational
genetic transmission as a large-time process assuring both the evolution by the transference of
the new adaptation characteristics to the next generations and the survival of the specie.
Observing the anti-entropic nature of the information activity mobilized to support the living
structure, there were identified the anti-entropic, antigravitational and reverse temporal arrow
features that the thought could access under special focusing conditions, similar to those of
antimatter, explaining the paranormal capacities like premonition, psychotherapy, telekinesis
and levitation, particularly the cloud dissipation, induced/supported by the mind power
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