Postal card from Joseph Roskelley

Postal card concerning a copy of the catalogue for Utah Agricultural College

Becoming a Goat: Leaving Mediocracy to the Sheep

Many new tutors can become quickly overwhelmed by their lack of experience coupled with a driving desire to perform well in the tutoring session. This dream to become a great tutor can be quickly snuffed out by lacking the confidence and the knowledge of how to achieve our full potential as tutors. In this essay, I will discuss two specific ways that we, as tutors, can go from “good” to “great” and ultimately become the tutors we strive to be. Through adaptability and positivity, we can leave behind the anxiety-stricken herd of aimless sheep and strike out on our own to become free-thinking goat-tutors

The Determinants of the Debt Maturity Decision for Real Estate Investment Trusts

This research uses the maturity of incremental bond issues and the weighted-average maturity of all outstanding debt and tests various theories from the corporate debt maturity literature to discover if real estate investment trust (REIT) debt maturity is influenced by liquidity risk, asymmetric information, personal taxes, and agency problems. The findings reveal that there is little to no evidence for the liquidity and asymmetric information hypotheses; however, there is evidence that personal taxes influence the maturity of REIT incremental debt issues, and agency problems play a role in determining the incremental and average debt maturity of REITs

The Use of a Mobile Compression Device Following a Lower Extremity Total Joint Arthroplasty Can Provide Venous Thromboembolic Prophylaxis Comparable to Current Pharmacological Anticoagulation Protocols

Background: Venous thromboembolisms (VTE) are an important complication following arthroplasty of the knees and hips, and proper prophylaxis protocol continues to be a source of debate in the medical community. In the past patients have been managed with pharmaceutical anticoagulants (eg, LMWH), mechanical compression, or a combination of the two. The inability to use mechanical compression on an outpatient basis has limited its use in the past, but the introduction of an outpatient mobile compression devices (MCDs) that monitors compliance has brought mobile compression devices to the forefront of VTE prophylaxis research. The aim of this review is to evaluate the use of MCDs as compared to pharmaceutical anticoagulants. Methods: Exhaustive search was conducted using Medline-OVID, CINAHL, and Web of Science using the keywords: mobile compression. All results were reviewed and selected according to the predefined eligibility criteria. Relevant articles were assessed for quality using GRADE. Results: Two studies met inclusion criteria and were included in this systematic review. A randomized control trial with 414 participants was unable to determine equivalency between the MCD and LMWH at VTE prophylaxis due to small sample size. They were however able to demonstrate a significant decrease in major bleeding events with use of the MCD. A prospective observational study with 23 260 participants demonstrated statistically noninferior VTE prophylaxis between the MCD group and the pharmaceutical anticoagulant group. Conclusion: Use of a MCD following a total joint arthroplasty (TJA) in the lower extremity may provide statistically noninferior VTE prevention rates when compared to the current pharmacological treatment options. Unlike pharmacologic anticoagulants, the use of a MCD does not increase the ris of a major bleeding event. This elimination of major bleeding complications makes implementation of MCD use following a TJA instead of anticoagulants a promising option for cost effective VTE prophylaxis. Keywords: Mobile compression, Arthroplasty, Venous thromboembolism, pharmaceutical anticoagulant

Cómo se decide la programación sobre salud en radio y televisión

Hace unos años, Estados Unidos era el país que producía más noticias de salud, pero la tendencia ha cambiado y en la actualidad muchos países igualan e incluso han superado esa barrera, debido a que el mercado de la difusión estadounidense está muy fragmentado. En el Seminario «Salud y opinión pública» se analizaron más a fondo dos casos de televisión: el de la CNN y el del programa «La 2 Noticias». En cuanto a la radio, el análisis de la información sobre salud que ofrecen las ondas españolas estuvo a cargo de un periodista y un médico que se dedican a la comunicación en salud

ERK1/2, PI3K and p70S6K are important mediators for HGF-induced migration and invasion in human ovarian cancer cells

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Podocalyxin in the Diagnosis and Treatment of Cancer

Kelly M. McNagny, Michael R. Hughes, Marcia L. Graves, Erin J. DeBruin, Kimberly Snyder, Jane Cipollone, Michelle Turvey, Poh C. Tan, Shaun McColl and Calvin D. Roskelle

Chitosan microparticles gel for In vitro 3D culture of human chondrocytes

[EN] Chondrocytes are frequently cultured embedded in gels that provide them with a three-dimensional environment. Nevertheless cells in these constructs cannot remodel their neighbourhood when producing their own extracellular matrix. In this work we explore 3D environments that the cells can easily remodel. For this, human mature chondrocytes were cultured in the three-dimensional environment created by chitosan microparticles whose diameter is in the order of magnitude of the cell size. Chondrocytes and microparticles suspensions were mixed and the agglomerates were cultured in static tubes in chondrogenic medium. The poor adhesion between cells and chitosan surface maintained the mobility of the ensemble. In these conditions chondrocytes are viable during the 28 days of culture. The cells produce glycosaminoglycans, S100 and collagen type II up to 14 days of culture although production of type I collagen is also noticeable.J.L. Gomez Ribelles acknowledges the support of the Spanish Ministerio de Ciencia e Innovacion through MAT2010-21611-C03-00 project (including the FEDER financial support). CIBER-BBN is an initiative funded by the VI National R&D&I Plan 2008-2011, Iniciativa Ingenio 2010, Consolider Program, CIBER Actions and financed by the Instituto de Salud Carlos III with assistance from the European Regional Development Fund. N Garcia-Giralt acknowledges the support by grants from the Generalitat de Catalunya (DIUE 2009 SGR 818, 2009 SGR 971) and the Red Tematica de Investigacion Cooperativa en Envejecimiento y Fragilidad (RETICEF) and FEDER funds. Grand MAT2007-66759-C03-02 of Plan Nacional del MINISTERIO DE EDUCACION Y CIENCIA are also acknowledged.Garcia-Giralt, N.; García Cruz, DM.; Nogues, X.; Escobar Ivirico, JL.; Gómez Ribelles, JL. (2013). Chitosan microparticles gel for In vitro 3D culture of human chondrocytes. RSC Advances. 3(18):6362-6368. doi:10.1039/c3ra23173aS6362636831