7,225 research outputs found

    Harmonic Superspaces and Superconformal Fields

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    Representations of four-dimensional superconformal groups on harmonic superfields are discussed. It is argued that any representation can be given as a superfield on many superflag manifolds. Representations on analytic superspaces do not require constraints. We discuss short representations and how to obtain them as explicit products of fundamental fields. We also discuss superfields that transform under supergroups.Comment: 7 pages, JHEP Proceedings style. Contribution to the Proceedings of the TMR Conference "Non-Perturbative Quantum Effects 2000," Paris, September 200

    Admissions of International Graduate Students: Art or Science? A Business School Experience

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    International students are often well represented in graduate programmes in North America and Europe. Information on foreign countries' education systems and grading schemes is available but cross-country comparisons are often challenging and highly subjective. Therefore, universities have a clear need for calibrating admissions of international students to ensure a fair and cost effective selection process. By comparing the performance of international students in their host institution with their entry qualifications we devise a simple approach to detecting systematic biases in the perceived quality of the applicants and propose corrective actions. We find that by using public information on cross-country comparisons of academic qualifications, country selection biases can occur and produce a substantial impact on international students' performance and failure rates. Our model is based on admission data that are routinely collected by universities which should ensure its broad applicability.admissions, country bias, entry qualifications, failure probability

    Testing the use of viscous remanent magnetisation to date flood events

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    © 2015 Muxworthy, Williams and Heslop. Using erratics associated with large flood events, this paper assesses whether their viscous remanent magnetisation (VRM) can be used to date the flood events. We tested this method using flood erratics from three large events: (1) the Late Pleistocene Bonneville mega-flood in Idaho, USA, (~14–18 ka), (2) the 1918 A.D. Mt. Katla, Iceland, eruption and associated jökulhaup (meltwater flood) at Mýrdalssandur, and (3) the Markarfljót jökulhaup due to an earlier eruption of Mt. Katla (~2.5 ka). We measured 236 specimens, 66 of which yielded clear identifiable and measurable viscous magnetisation signals from erratics with clustered VRM directions. From the VRM unblocking temperatures, age estimates were made. The age estimate for the most recent event (Mýrdalssandur) worked well, with a median estimated age of 80 years (with individual erratic estimates distributed between 61–105 years) compared to the known age of 91 years. The ages of the other two events were over-estimated. The estimates for Markarfljót [15 ka (7–33 ka)] were based on the results of just one erratic. For the Bonneville flood the estimates were too old, however, this locality had the largest uncertainty in the ambient temperature used in the age determination; the VRM acquired is strongly dependent on the ambient temperature, the older the event the greater the uncertainty. Southern Idaho currently has hot summers, with average summer maximum temperatures of ~31°C, but a mean annual temperature of only ~ 9°C. It is suggested that the VRM dating method works best for recent events (<2–3 ka) where the ambient temperature history can be constrained

    Personalisation in mental health: A review of the evidence

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    Terrestrial laser scanning and 3D imaging: Heritage case study – The Black Gate, Newcastle Upon Tyne

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    This paper offers a case study on the recording of a section of wall on a complex heritage building, the Black Gate in Newcastle upon Tyne. The paper adopts case study methodology to assess the appropriateness of using a long range scanner based upon pulse technology for the recording of part of this historic structure and describes the scanning instruments adopted as well as the selection of appropriate software for the pre-processing and documentation. The study offers an overview of the survey planning stages, field operation, and processing of 3D point cloud data using the third party software adopted, including problems encountered. Issues emerging are discussed, in both the 2D and 3D modelling of detailed surfaces from point cloud data, and in the process of software selection, data preparation and export, pre-processing of point cloud data, meshing and the creation of 2D geometry and 3D animations. The paper describes the end results offered as deliverables for this project, and offers recommendations for a working method that can produce data suitable for producing stone-by-stone elevation drawings. The work processes and cost / time indicators are included in this case study and conclusions will consider whether the technique adopted could lead to an improved solution for heritage recording compared to those traditional techniques which are currently employed to produce stone-by-stone elevations. Areas for future research are identified

    Noise from spatial heterogeneity changes signal amplification magnitude and increases the variability in dose responses

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    In most molecular level simulations, spatial heterogeneity is neglected by the well-mixed condition assumption. However, the signals of biomolecular networks are affected from both time and space, which are responsible for diverse physiological responses. To account the spatial heterogeneity in the kinetic model, we consider multiple subvolumes of a reaction, introduce parameters representing transfer of ligands between the volumes, and reduce this to an error-term representing the difference between the well-mixed condition and the actual spatial factors. The error-term approach allows modelling of varying spatial heterogeneity without increasing computational burden exponentially. The effect of varying this term, d, between 0 (well-mixed) and 1 (no mixing) and of adding noise to the kinetic constants was then investigated and correlated with knowledge of the behaviour of real systems and situations where network models are inadequate. The spatial distribution effects on the epidermal growth factor receptor (EGFR) in human mammary epithelial tissue, which is involved in proliferation and tumorigenesis, are studied by introducing noisy kinetic constants. The steady-state of the dose response in the EGFR is strongly affected by spatial fluctuations. The ligand-bound receptor is reduced up to 50% from the response without spatial fluctuations and the variance of the steady-state is increased at least 2-fold from the one for no spatial fluctuations. On the other hand, dynamic properties such as the rising time and overshoot are less sensitive to spatial noise

    Stochastic noise and synchronisation during Dictyostelium aggregation make cAMP oscillations robust

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    The molecular network, which underlies the oscillations in the concentration of adenosine 3′, 5′-cyclic monophosphate (cAMP) during the aggregation phase of starvation-induced development in Dictyostelium discoideum, achieves remarkable levels of robust performance in the face of environmental variations and cellular heterogeneity. However, the reasons for this robustness remain poorly understood. Tools and concepts from the field of control engineering provide powerful methods for uncovering the mechanisms underlying the robustness of these types of biological systems. Using such methods, two important factors contributing to the robustness of cAMP oscillations in Dictyostelium are revealed. First, stochastic fluctuations in the molecular interactions of the intracellular network, arising from random or directional noise and biological sources, play an important role in preserving stable oscillations in the face of variations in the kinetics of the network. Second, synchronisation of the aggregating cells through the diffusion of extracellular cAMP appears to be a key factor in ensuring robustness to cell-to-cell variations of the oscillatory waves of cAMP observed in Dictyostelium cell cultures. The conclusions have important general implications for the robustness of oscillating biomolecular networks (whether seen at organism, cell, or intracellular levels and including circadian clocks or Ca2+ oscillations, etc.), and suggest that such analysis can be conducted more reliably by using models including stochastic simulations, even in the case where molecular concentrations are very high

    Using a Flow Through device to reconstruct the thermal gradient in the water column based on G. inflata Mg/Ca

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    We present Mg/Ca analyses performed via a Flow Through sequential dissolution device connected to an ICP-OES on the planktonic foraminifer Globorotalia inflata. The aim of the study is to explore the possibility to reconstruct the thermal gradient in the water column by separating non-crusted and crusted calcite phases in the tests of G. inflata using the difference between their Mg/Ca ratios as a measure of the thermal gradient. An important assumption is that the non-crusted part of the tests is calcified in shallow, warmer water than the crusted part. For analyses a range of different preparation steps were used to determine the ideal way of separating the phases. Foraminifer tests were (not) cleaned, (not) crushed, and (not) pulverized before online analysis with the FT device. To analyze samples with a FT device the foraminifer tests are placed on a filter with a mesh of 0.45 μm preventing clay minerals to wash through. A sequential dissolution protocol first rinses the samples with buffered Seralpur water before QD HNO3 is added in small steps to create a ramp of increasing acid strength. As acid is kept constant at each concentration for several minutes, dissolution of a specific calcite phase can take place. Initial results show that it is most effective to slightly crush the tests without applying standard cleaning procedures, but rather analyze them without cleaning. Samples were selected from the South Atlantic (core tops and specific downcore samples) and the Mediteterranean (plankton tows). All samples were chosen based on previous work on them to provide comparison with routinely analysed Mg/Ca ratios. The South Atlantic samples have been analyzed extensively as bulk samples separated in difference size fractions and crusted vs. non-crusted (Groeneveld and Chiessi). The Mediterranean samples were not only analyzed as bulk samples but also by Laser Ablation ICP-MS (von Raden et al.). Results show that bulk analyses are reliably reproduced by the FT method, especially for samples which are dominated by crusted calcite. Samples which were uncrusted often gave much higher Mg/Ca ratios than the bulk analyses. These higher Mg/Ca ratios mainly occur in the plankton tow samples and were also identified with Laser Ablation ICP-MS. A possible reason for this could be the presence of a high Mg amorphous calcite layer on the outside of foraminifer tests which have not completed their calcification yet as was recently also pointed out in several other studies. Identification of the crusted and uncrusted phases, and therewith a thermal gradient, seems to give the expected differences but a more rigorous statistical treatment is needed to pinpoint singular dissolution phases
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