KINESIOLOGÍA Y ENFERMEDAD PULMONAR OBSTRUCTIVA CRÓNICA

RESUMENLos pacientes con Enfermedad Pulmonar Obstructiva Crónica (EPOC) junto con desarrollar las alteraciones respiratorias propias de la patología desarrollan también alteraciones multisistémicas que repercuten principalmente en la musculatura respiratoria y periférica, reduciendo la capacidad de tolerancia física del paciente a las actividades diarias.Junto al tratamiento médico, la kinesiología representa una importante herramienta terapéutica, ya que se orienta a mantener las capacidades físicas del paciente, tanto en sus condicionantes respiratorias como motoras.El objetivo de este artículo es mostrar la importancia de la kinesiología en este grupo de pacientes, tanto durante su periodo de hospitalización como en el período de rehabilitación después del alta.SUMMARYThe majority of patients with Chronic Obstructive Pulmonary Disease (COPD) develop the classic respiratory alterations, as well as systemic dysfunctions, by which contribute to the deterioration of the respiratory and the skeletal muscles. Consequently, all of this muscle dysfunction reduce the physical capacity in the COPD patients to develop their diary activities.The physical therapy as a complementary treatment of the medical management, is an important therapeutic tool to maintain the physical abilities of the COPD patients as much in the respiratory function as in the motor area.This paper attempts to review the importance of the physical therapy in the COPD patients, such as in the hospitalization time and in the consecutive rehabilitation time

Supplementary data for article: Keškić, T.; Čobeljić, B.; Gruden, M.; Anđelković, K.; Pevec, A.; Turel, I.; Radanović, D.; Zlatar, M. What Is the Nature of Interactions of BF4–, NO3–, and ClO4– to Cu(II) Complexes with Girard’s T Hydrazine? When Can Binuclear Complexes Be Formed? Crystal Growth & Design 2019, 19 (8), 4810–4821. https://doi.org/10.1021/acs.cgd.9b00760

Supporting information for: [https://doi.org/10.1021/acs.cgd.9b00760]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789/3679

Influence of exposure to cold thermal environment on core and skin temperatures

Exposure to extreme cold triggers in humans various of physiological responses, which is necessary to control is necessary when it comes to occupational exposure. The objective of the present study was to analyze the evolution of core temperature, mean skin temperature during exposure to extreme cold (-20 degrees C), with the usual protection for this type of exposure. From a total of 12 healthy individuals using a climatic chamber, intra-abdominal temperature and skin temperature were measured during and after the exposure period. The results demonstrate a decrease in core temperature and mean skin temperature at the initial moments of the test, from an increase to the end of exposure. The choice of individual protective equipment with the appropriate thermal insulation as well as the protection of the extremities is fundamental in order to guarantee the safety and the comfort of the exposed individuals. Further studies should be conducted using larger samples with a greater diversity of individual factors

Exploring the Role of Relational Practices in Water Governance Using a Game-Based Approach

The growing complexity and interdependence of water management processes requires the involvement of multiple stakeholders in water governance. Multi-party collaboration is increasingly vital at both the strategy development and implementation levels. Multi-party collaboration involves a process of joint decision-making among key stakeholders in a problem domain directed towards the future of that domain. However, the common goal is not present from the beginning; rather, the common goal emerges during the process of collaboration. Unfortunately, when the conflicting interests of different actors are at stake, the large majority of environmental multi-party efforts often do not reliably deliver sustainable improvements to policy and/or practice. One of the reasons for this, which has been long established by many case studies, is that social learning with a focus on relational practices is missing. The purpose of this paper is to present the design and initial results of a pilot study that utilized a game-based approach to explore the effects of relational practices on the effectiveness of water governance. This paper verifies the methods used by addressing the following question: are game mechanisms, protocols for facilitation and observation, the recording of decisions and results, and participant surveys adequate to reliably test hypotheses about behavioral decisions related to water governance? We used the “Lords of the Valley” (LOV) game, which focuses on the local-level management of a hypothetical river valley involving many stakeholders. We used an observation protocol to collect data on the quality of relational practices and compared this data with the quantitative outcomes achieved by participants in the game. In this pilot study, we ran the game three times with different groups of participants, and here we provide the outcomes within the context of verifying and improving the methods

Supplementary data for article: Milenković, M. R.; Papastavrou, A. T.; Radanović, D. D.; Pevec, A.; Jagličić, Z.; Zlatar, M.; Gruden, M.; Vougioukalakis, G. C.; Turel, I.; Anđelković, K. K.; et al. Highly-Efficient N-Arylation of Imidazole Catalyzed by Cu(II) Complexes with Quaternary Ammonium-Functionalized 2-Acetylpyridine Acylhydrazone. Polyhedron 2019, 165, 22–30. https://doi.org/10.1016/j.poly.2019.03.001

Related to accepted version: [http://cherry.chem.bg.ac.rs/handle/123456789/2865]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789/2858]Supplementary material for: [https://www.sciencedirect.com/science/article/pii/S0277538719301664?via%3Dihub

Highly-efficient N-arylation of imidazole catalyzed by Cu(II) complexes with quaternary ammonium-functionalized 2-acetylpyridine acylhydrazone

The reaction of (E)-N,N,N-trimethyl-2-oxo-2-(2-(1-(pyridin-2-yl)ethylidene)hydrazinyl)ethan-1-aminium-chloride (HLCl) with copper(II) perchlorate led to mononuclear [CuLCl]ClO 4 complex (1). The same reaction with excess of sodium azide gives dinuclear azido double end-on bridged Cu(II) complex [Cu 2 L 2 (μ- 1,1 -N 3 ) 2 ](ClO 4 ) 2 (2). In both complexes hydrazone ligand is NNO coordinated in monodeprotonated formally neutral zwitter-ionic form. Complexes were characterized by elemental analysis, IR spectroscopy and single-crystal X-ray crystallography. Variable‐temperature magnetic susceptibility measurements for dinuclear Cu(II) complex showed intra-dimer ferromagnetic coupling between Cu(II) ions (J = 7.4 cm −1 ). DFT-BS calculations provided explanation for magnetic properties of dinuclear Cu(II) complex. Both complexes were shown to highly efficiently catalyze the N-arylation of imidazole and benzimidazole with electron-poor or electron-rich aryl iodides, under user-friendly and sustainable conditions.This is the peer-reviewed version of the following article: Milenković, M. R.; Papastavrou, A. T.; Radanović, D.; Pevec, A.; Jagličić, Z.; Zlatar, M.; Gruden, M.; Vougioukalakis, G. C.; Turel, I.; Anđelković, K.; et al. Highly-Efficient N-Arylation of Imidazole Catalyzed by Cu(II) Complexes with Quaternary Ammonium-Functionalized 2-Acetylpyridine Acylhydrazone. Polyhedron 2019, 165, 22–30. [https://doi.org/10.1016/j.poly.2019.03.001]Supplementary material: [http://cherry.chem.bg.ac.rs/handle/123456789/3006

Supplementary data for the article: Darmanović, D.; Shcherbakov, I. N.; Duboc, C.; Spasojević, V.; Hanžel, D.; Anđelković, K.; Radanović, D.; Turel, I.; Milenković, M.; Gruden, M.; et al. Combined Experimental and Theoretical Investigation of the Origin of Magnetic Anisotropy in Pentagonal Bipyramidal Isothiocyanato Co(II), Ni(II), and Fe(III) Complexes with Quaternary-Ammonium-Functionalized 2,6-Diacetylpyridine Bisacylhydrazone. Journal of Physical Chemistry C 2019, 123 (51), 31142–31155. https://doi.org/10.1021/acs.jpcc.9b08066

Supplementary material for: [https://doi.org/10.1021/acs.jpcc.9b08066]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789/3855]Related to accepted version: [http://cherry.chem.bg.ac.rs/handle/123456789/3856

Density functional theory study of the multimode Jahn-Teller effect – ground state distortion of benzene cation

The multideterminental-DFT approach performed to analyze Jahn-Teller (JT) active molecules is described. Extension of this method for the analysis of the adiabatic potential energy surfaces and the multimode JT effect is presented. Conceptually a simple model, based on the analogy between the JT distortion and reaction coordinates gives further information about microscopic origin of the JT effect. Within the harmonic approximation the JT distortion can be expressed as a linear combination of all totally symmetric normal modes in the low symmetry minimum energy conformation, which allows calculating the Intrinsic Distortion Path, IDP, exactly from the high symmetry nuclear configuration to the low symmetry energy minimum. It is possible to quantify the contribution of different normal modes to the distortion, their energy contribution to the total stabilization energy and how their contribution changes along the IDP. It is noteworthy that the results obtained by both multideterminental-DFT and IDP methods for different classes of JT active molecules are consistent and in agreement with available theoretical and experimental values. As an example, detailed description of the ground state distortion of benzene cation is given

Supporting information for: "Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity"

In this paper, Cu(II), Mn(II) and Zn(II) complexes with N,N,N-trimethyl-2-oxo-2-(2-(1-(thiazol-2-yl)ethylidene)hydrazinyl)ethan-1-aminium chloride (HL1Cl) were synthesized and characterized by single-crystal X-ray diffraction, IR spectroscopy, elemental analysis and DFT calculations. In all three complexes, a ligand (L1) is coordinated in a deprotonated formally neutral zwitterionic form via NNO donor set atoms. Cu(II) and Zn(II) form mononuclear penta-coordinated complexes [CuL1(N3)(CH3OH)]BF4 and [ZnL1(N3)2], respectively, while Mn(II) forms a binuclear [Mn2L12(μ-1,1-N3)2(N3)2]·2CH3OH complex, with unusual distorted trigonal-prismatic geometry around the metal centers. The antimicrobial activity of these complexes was tested against a panel of Gram-negative and Gram-positive bacteria, two yeasts and one fungal strain. The binuclear Mn(II) complex showed antifungal activity of similar intensity to amphotericin B. Based on the results of the brine shrimp test and DPPH radical scavenging activity, the most active Cu(II) and Mn(II) complexes were selected for evaluation of cytotoxic activity against five malignant cancer cell lines (HeLa, A375, MCF7, PC-3 and A549) and one normal cell line HaCaT. Both complexes showed significant activity. It should be pointed out that the activity of the Mn(II) complex against the MCF7 breast cancer cell line is only slightly weaker than that of cisplatin, but with selectivity to the tumor cell line in comparison to normal HaCaT cells, which is non-existent in the case of cisplatin.The supporting information for: Stevanović, Nevena, Zlatar, Matija, Novaković, Irena, Pevec, Andrej, Radanović, Dušanka, Matić, Ivana Z., Đorđić Crnogorac, Marija, Stanojković, Tatjana, Vujčić, Miroslava, Gruden, Maja, Sladić, Dušan, Anđelković, Katarina, Turel, Iztok, Čobeljić, Božidar, "Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity" in Dalton Transactions, 51, no. 1 (2022):185-196, [https://doi.org/10.1039/D1DT03169D]Published article: [https://cherry.chem.bg.ac.rs/handle/123456789/4857]Related crystallographic data (CCDC 2110386): [https://cherry.chem.bg.ac.rs/handle/123456789/4859]Related crystallographic data (CCDC 2110387): [https://cherry.chem.bg.ac.rs/handle/123456789/4860]Related crystallographic data (CCDC 2110388): [https://cherry.chem.bg.ac.rs/handle/123456789/4861