Caracterização físicoquímica do mosto e do vinho de uvas Moscato Giallo cultivadas sob cobertura plástica.

O objetivo deste trabalho foi avaliar o efeito da cobertura plástica sobre o mosto e a qualidade do vinho da cultivar Moscato Giallo.bitstream/CNPUV-2009-09/10530/1/cot091.pd

Análise sensorial descritiva de vinhos tintos comerciais de Pinto Bandeira da safra 2006.

Clima, solo e relevo são fatores importantes que detenninam a composição química da uva e as caracterlsticas sensoriais dos vinhos. Os vinhedos implantados na região de Pinto Bandeira, localizada na Serra Gaúcha, estão a mais de 500· m de altitude podendo produzir uvas e, consequentemente, vinhos com caracterlsticas peculiares. As amostras anualmente encaminhadas para a avaliação sensorial no êmbito do Conselho Regulador da Asprovinho e da Embrapa Uva e Vinho, foram degustadas em 2006, por um painel de sete enôlogos.Resumo

Supersymmetric gyratons in five dimensions

We obtain the gravitational and electromagnetic field of a spinning radiation beam-pulse (a gyraton) in minimal five-dimensional gauged supergravity and show under which conditions the solution preserves part of the supersymmetry. The configurations represent generalizations of Lobatchevski waves on AdS with nonzero angular momentum, and possess a Siklos-Virasoro reparametrization invariance. We compute the holographic stress-energy tensor of the solutions and show that it transforms without anomaly under these reparametrizations. Furthermore, we present supersymmetric gyratons both in gauged and ungauged five-dimensional supergravity coupled to an arbitrary number of vector supermultiplets, which include gyratons on domain walls.Comment: 25 pages, no figures, uses JHEP3.cls. Final version to appear in CQ

Cobertura plástica: contribuição para a melhoria da qualidade dos vinhos?

A sanidade das uvas é um aspecto importante na definição da qualidade dos vinhos. Esta é relevante por que algumas doenças fúngicas, além de prejudicarem a produção das uvas propriamente dita, afetam a qualidade do vinho, durante o processo de vinificação e no produto final, acentuando odores indesejáveis e acéticoso Uvas com Botrytis cinerea, por exemplo, contêm tirosinases e lacases, que são enzimas responsáveis pela oxidação enzimática dos compostos fenólicos, prejudicando a cor, o aroma e o sabor dos vinhos.bitstream/item/200268/1/9329-2008-p.17-18.pd

Biological effects of EF24, a curcumin derivative, alone or combined with mitotane in adrenocortical tumor cell lines

Background: Curcumin has numerous properties and is used in many preclinical conditions, including cancer. It has low bioavailability, while its derivative EF24 shows enhanced solubility. However, its effects have never been explored in adrenocortical tumor cell models. The efficacy of EF24 alone or combined with mitotane (reference drug for adrenocortical cancer) was evaluated in two adrenocortical tumor cell lines, SW13 and H295R. Method and Results: EF24 reduced cell viability with an IC50 (half maximal inhibitory concentration) of 6.5 \ub1 2.4 \ub5M and 4.9 \ub1 2.8 \ub5M for SW13 and H295R cells, respectively. Combination index (EF24 associated with mitotane) suggested an additivity effect in both cell lines. Cell cycle analysis revealed an increase in subG0/G1 phase, while motility assay showed a decrease in migratory cell capacity, and similarly, clonogenic assay indicated that EF24 could reduce colony numbers. Furthermore, Wnt/\u3b2-catenin, NF-\u3baB, MAPK, and PI3k/Akt pathways were modulated by Western blot analysis when treating cells with EF24 alone or combined with mitotane. In addition, intracellular reactive oxygen species levels increased in both cell lines. Conclusion: This work analyzed EF24 in adrenocortical tumor cell lines for the first time. These results suggest that EF24 could potentially impact on adrenocortical tumors, laying the foundation for further research in animal models

Efeito da cobertura plástica na composição de vinhos Moscato Giallo.

A utilização da cobertura plástica impermeável sobre as linhas de cultivo para a produção de uvas destinadas à vinificação é bastante incipiente. Deste modo, há poucas informações a respeito da influência desta tecnologia sobre a qualidade enológIca dos vinhos.Resumo

Anticancer Effects of Wild Mountain Mentha longifolia Extract in Adrenocortical Tumor Cell Models

Mint [Mentha longifolia (L.) Hudson] is an aromatic plant that belongs to Lamiaceae family. It is traditionally used as herbal tea in Europe, Australia and North Africa and shows numerous pharmacological effects, such as spasmolytic, antioxidant, antimicrobial and anti-hemolytic. Recently, its antiproliferative role has been suggested in a small number of tumor cell models, but no data are available on adrenocortical carcinoma, a malignancy with a survival rate at 5 years of 20%\u201330% which frequently metastasize. This work aimed to study the effects of Mentha longifolia L. crude extract (ME) on two adrenocortical tumor cell models (H295R and SW13 cells). Chemical composition of ME was assessed by gas-chromatography/mass spectrometry and NMR spectroscopy analysis. Brine shrimp lethality assay showed ME effects at >0.5 \ub5g/\ub5l (p 0.5 \ub5g/\ub5l, p 0.5 \ub5g/\ub5l, p < 0.05), while Wright staining demonstrated the presence of both necrotic and apoptotic cells. Cell cycle analysis showed a strong increase in subG0/G1 phase, related to cell death. Furthermore, MAPK and PI3k/Akt pathways were modulated by Western blot analysis when treating cells with ME alone or combined with mitotane. The crude methanolic extract of wild mountain mint can decrease cell viability, vitality and survival of adrenocortical tumor cell models, in particular of SW13 cells. These data show the potential anticancer effects of ME, still more work is needed to corroborate these findings

Aroma de vinhos Lorena elaborados com diferentes leveduras.

A liberação dos terpenos em uvas moscatéis, pela ação de glicosidases das leveduras, pode aumentar e/ou modificar o aroma de vinhos. Este experimento comparou as características sensoriais de vinhos BRS Lorena (Malvasia Bianca x Seyval) elaborados com diferentes leveduras.Resumo

Accurate Machine Learning Atmospheric Retrieval via a Neural Network Surrogate Model for Radiative Transfer

Atmospheric retrieval determines the properties of an atmosphere based on its measured spectrum. The low signal-to-noise ratio of exoplanet observations require a Bayesian approach to determine posterior probability distributions of each model parameter, given observed spectra. This inference is computationally expensive, as it requires many executions of a costly radiative transfer (RT) simulation for each set of sampled model parameters. Machine learning (ML) has recently been shown to provide a significant reduction in runtime for retrievals, mainly by training inverse ML models that predict parameter distributions, given observed spectra, albeit with reduced posterior accuracy. Here we present a novel approach to retrieval by training a forward ML surrogate model that predicts spectra given model parameters, providing a fast approximate RT simulation that can be used in a conventional Bayesian retrieval framework without significant loss of accuracy. We demonstrate our method on the emission spectrum of HD 189733 b and find good agreement with a traditional retrieval from the Bayesian Atmospheric Radiative Transfer (BART) code (Bhattacharyya coefficients of 0.9843--0.9972, with a mean of 0.9925, between 1D marginalized posteriors). This accuracy comes while still offering significant speed enhancements over traditional RT, albeit not as much as ML methods with lower posterior accuracy. Our method is ~9x faster per parallel chain than BART when run on an AMD EPYC 7402P central processing unit (CPU). Neural-network computation using an NVIDIA Titan Xp graphics processing unit is 90--180x faster per chain than BART on that CPU.Comment: 16 pages, 4 figures, submitted to PSJ 3/4/2020, revised 1/22/2021. Text restructured and updated for clarity, model updated and expanded to work for range of hot Jupiters, results/plots updated, two new appendices to further justify model selection and methodolog

Black strings in AdS_5

We present non-extremal magnetic black string solutions in five-dimensional gauged supergravity. The conformal infinity is the product of time and S^1xS_h, where S_h denotes a compact Riemann surface of genus h. The construction is based on both analytical and numerical techniques. We compute the holographic stress tensor, the Euclidean action and the conserved charges of the solutions and show that the latter satisfy a Smarr-type formula. The phase structure is determined in the canonical ensemble, and it is shown that there is a first order phase transition from small to large black strings, which disappears above a certain critical magnetic charge that is obtained numerically. For another particular value of the magnetic charge, that corresponds to a twisting of the dual super Yang-Mills theory, the conformal anomalies coming from the background curvature and those arising from the coupling to external gauge fields exactly cancel. We also obtain supersymmetric solutions describing waves propagating on extremal BPS magnetic black strings, and show that they possess a Siklos-Virasoro reparametrization invariance.Comment: 40 pages, 7 figures, JHEP3. v2: minor corrections, 2 references added. v3: typos in holographic stress tensor corrected, 3 references adde