The Effect of RANKL/OPG Balance on Reducing Implant Complications

Despite the phenomenal success of implants particularly in the realms of dentistry and orthopaedics, there are still challenges to overcome. The failure of implants resulting from infection, prosthetic loosening, and non-union continue to be the most notorious examples. The cascade of fracture healing and bone repair, especially with the presence of an implant, is complex because it involves a multifaceted immune response alongside the intricate process of bone formation and remodelling. Bone loss is a serious clinical problem that is frequently accompanied by chronic inflammation, illustrating that there is a convoluted relationship between inflammation and bone erosion. The effects of pro-inflammatory factors play a significant role in initiating and maintaining osteoclastogenesis that results in bone resorption by osteoclasts. This is because there is a disruption of the relative ratio between Receptor Activator of Nuclear Factor κB-Ligand (RANKL) and osteoprotegerin (OPG), which is central to modulating bone repair and remodelling. This review aims to provide a background to the bone remodelling process, the bone repair cascade post-implantation, and the associated complications. Furthermore, current clinical solutions that can influence bone formation via either internal or extrinsic mechanisms will be described. These efficacious treatments for osteolysis via targeting the RANKL/OPG ratio may be crucial to reducing the incidence of related implant failures in the future

Modeling and Optimization of the Dilute Sulfuric Acid Treatment on Corn Stover at Low Temperature

Corn stover was hydrolyzed using dilute sulfuric acid at concentrations of 2, 4, and 6% over reaction times up to 300 minutes at 80oC. The concentrations of sugars (xylose and glucose) and degradation product (furfural) were determined and the kinetic parameters of mathematical models for predicting them in the hydrolysates were obtained. According to the models, an optimal condition for hydrolysis was achieved which was 5% H2SO4 at 80°C for 240min and the liquor contained up to 13.21g/l xylose, 5.07g /l glucose and 0.80g/l furfural. The hydrolysates obtained from corn stover can be used to produce hydrogen and methane by anaerobic fermentation process. The models could be used successfully to predict the concentrations of xylose, glucose and furfural within 0-300min under experimental acid concentration

Efficient scheme for one-way quantum computing in thermal cavities

We propose a practical scheme for one-way quantum computing based on efficient generation of 2D cluster state in thermal cavities. We achieve a controlled-phase gate that is neither sensitive to cavity decay nor to thermal field by adding a strong classical field to the two-level atoms. We show that a 2D cluster state can be generated directly by making every two atoms collide in an array of cavities, with numerically calculated parameters and appropriate operation sequence that can be easily achieved in practical Cavity QED experiments. Based on a generated cluster state in Box$^{(4)}$ configuration, we then implement Grover's search algorithm for four database elements in a very simple way as an example of one-way quantum computing.Comment: 6 pages, 3 figure

Quantum information processing using Josephson junctions coupled through cavities

Josephson junctions have been shown to be a promising solid-state system for implementation of quantum computation. The significant two-qubit gates are generally realized by the capacitive coupling between the nearest neighbour qubits. We propose an effective Hamiltonian to describe charge qubits coupled through the cavity. We find that nontrivial two-qubit gates may be achieved by this coupling. The ability to interconvert localized charge qubits and flying qubits in the proposed scheme implies that quantum network can be constructed using this large scalable solid-state system.Comment: 5 pages, to appear in Phys Rev A; typos corrected, solutions in last eqs. correcte

Superconductivity and single crystal growth of Ni0:05TaS2

Superconductivity was discovered in a Ni0:05TaS2 single crystal. A Ni0:05TaS2 single crystal was successfully grown via the NaCl/KCl flux method. The obtained lattice constant c of Ni0:05TaS2 is 1.1999 nm, which is significantly smaller than that of 2H-TaS2 (1.208 nm). Electrical resistivity and magnetization measurements reveal that the superconductivity transition temperature of Ni0:05TaS2 is enhanced from 0.8 K (2H-TaS2) to 3.9 K. The charge-density-wave transition of the matrix compound 2H-TaS2 is suppressed in Ni0:05TaS2. The success of Ni0:05TaS2 single crystal growth via a NaCl/KCl flux demonstrates that NaCl/KCl flux method will be a feasible method for single crystal growth of the layered transition metal dichalcogenides.Comment: 13pages, 6 figures, Published in SS

Single crystal growth and characterizations of Cu0.03TaS2 superconductors

Single crystal of Cu0.03TaS2 with low copper intercalated content was successfully grown via chemical iodine-vapor transport. The structural characterization results show that the copper intercalated 2H-Cu0.03TaS2 single crystal has the same structure of the CdI2-type structure as the parent 2H-TaS2 crystal. Electrical resistivity and magnetization measurements reveal that 2H-Cu0.03TaS2 becomes a superconductor below 4.2 K. Besides, electrical resistivity and Hall effects results show that a charge density wave transition occurs at TCDW = 50 K.Comment: 14 pages, 6 figures,revised versio

Study of J/psi decays to Lambda Lambdabar and Sigma0 Sigma0bar

The branching ratios and Angular distributions for J/psi decays to Lambda Lambdabar and Sigma0 Sigma0bar are measured using BESII 58 million J/psi.Comment: 11 pages, 5 figure

Measurements of J/psi Decays into 2(pi+pi-)eta and 3(pi+pi-)eta

Based on a sample of 5.8X 10^7 J/psi events taken with the BESII detector, the branching fractions of J/psi--> 2(pi+pi-)eta and J/psi-->3(pi+pi-)eta are measured for the first time to be (2.26+-0.08+-0.27)X10^{-3} and (7.24+-0.96+-1.11)X10^{-4}, respectively.Comment: 11 pages, 6 figure

BESII Detector Simulation

A Monte Carlo program based on Geant3 has been developed for BESII detector simulation. The organization of the program is outlined, and the digitization procedure for simulating the response of various sub-detectors is described. Comparisons with data show that the performance of the program is generally satisfactory.Comment: 17 pages, 14 figures, uses elsart.cls, to be submitted to NIM