Redukcja ekspozycji na promieniowanie podczas ablacji migotania przedsionków z wykorzystaniem systemu elektroanatomicznego 3D zintegrowanego z fluoroskopią w codziennej praktyce klinicznej

Introduction. Fluoroscopy integration with three dimensional (3D) electroanatomical mapping system may allow dose reduction while invasive electrophysiological procedures. In this retrospective study we present real-population experience with integrated model. Material and methods. Ninety-six patients with paroxysmal atrial fibrillation (AF) after radiofrequency pulmonary vein isolation have been analyzed. In 48 patients, 3D mapping system integrated with fluoroscopy (Carto 3 UniVu) has been used. Clinical and peri-procedural data, inclusive, fluoroscopy time and dose, in-hospital complications and efficacy rate at 6 months have been compared. Results. Patients treated with classic 3D mapping system were significantly older (p = 0.036). Both fluoroscopy mean time (11.6 ± 4.3 vs. 6.7 ± 2.9 minutes, p < 0.05) and a median of the fluoroscopy dose [460.0 (IQR: 288.0–785.5) vs. 271.0 (IQR 145.0–535.0) mGy, p < 0.05] have been significantly reduced by using Carto3 UniVu. Total procedure time was comparable between groups. Periprocedural complications and recurrence of clinical arrhythmia rate in 6-month follow-up were comparable. Conclusions. Utilization of novel 3D mapping systems with classic fluoroscopy integration supports the radiation time and the dose reduction during AF ablation procedure, without any adverse impact on the total procedure time, complication or success rate. This real-life population results corresponds with previously presented prospective studies.Wstęp. Integracja obrazu fluoroskopowego z systemem obrazowania elektroanatomicznego 3D może zmniejszać ekspozycję na promieniowanie jonizujące podczas zabiegów elektrofizjologicznych. W tym retrospektywnym badaniu zaprezentowano wyniki stosowania zintegrowanego systemu elektroanatomicznego u pacjentów poddawanych ablacji migotania przedsionków w codziennej praktyce. Materiał i metody. Przeanalizowano 96 pacjentów z napadowym migotaniem przedsionków poddanych zabiegowi izolacji żył płucnych prądem o częstotliwości radiowej. U 48 z nich wykorzystano system elektroanatomiczny 3D zintegrowany z fluoroskopią (Carto 3 UniVu). U pozostałych zastosowano klasyczny system elektroanatomiczny 3D (Carto 3). Analizie poddano dane kliniczne, a także okołozabiegowe, w szczególności dawkę i czas skopii, a także częstość powikłań i nawrotu arytmii w okresie 6 miesięcy. Wyniki. Pacjenci leczeni z użyciem klasycznego systemu 3D byli istotnie starsi (p = 0,036). We wszystkich przypadkach uzyskano całkowitą izolację żył płucnych. Zarówno średni czas skopii (11,6 ± 4,3 vs. 6,7 ± 2,9 min; p &lt; 0,05), jak i mediana dawki (460,0 [IQR 288,0–785,5] vs. 271,0 [IQR 145,0–535,0] mGy; p &lt; 0,05) były istotnie mniejsze u pacjentów w grupie, w której stosowano Carto 3 UniVu. Całkowity czas zabiegu w obu grupach był porównywalny. Częstości powikłań okołozabiegowych oraz nawrotu klinicznej arytmii były porównywalne w obu grupach. Wnioski. Wykorzystanie nowego systemu elektroanatomicznego 3D zintegrowanego z klasyczną fluoroskopią pozwala na zmniejszenie ekspozycji na promieniowanie jonizujące podczas zabiegów ablacji migotania przedsionków, nie wpływając jednocześnie negatywnie na czasu zabiegu, ryzyko komplikacji czy skuteczność. Dane te, uzyskane w toku codziennej praktyki, korespondują z wcześniejszymi dowodami uzyskanymi z badań klinicznych

Les droits disciplinaires des fonctions publiques : « unification », « harmonisation » ou « distanciation ». A propos de la loi du 26 avril 2016 relative à la déontologie et aux droits et obligations des fonctionnaires

The production of tt‾ , W+bb‾ and W+cc‾ is studied in the forward region of proton–proton collisions collected at a centre-of-mass energy of 8 TeV by the LHCb experiment, corresponding to an integrated luminosity of 1.98±0.02 fb−1 . The W bosons are reconstructed in the decays W→ℓν , where ℓ denotes muon or electron, while the b and c quarks are reconstructed as jets. All measured cross-sections are in agreement with next-to-leading-order Standard Model predictions.The production of $t\overline{t}$, $W+b\overline{b}$ and $W+c\overline{c}$ is studied in the forward region of proton-proton collisions collected at a centre-of-mass energy of 8 TeV by the LHCb experiment, corresponding to an integrated luminosity of 1.98 $\pm$ 0.02 \mbox{fb}^{-1}. The $W$ bosons are reconstructed in the decays $W\rightarrow\ell\nu$, where $\ell$ denotes muon or electron, while the $b$ and $c$ quarks are reconstructed as jets. All measured cross-sections are in agreement with next-to-leading-order Standard Model predictions

Multidifferential study of identified charged hadron distributions in ZZ-tagged jets in proton-proton collisions at s=\sqrt{s}=13 TeV

Jet fragmentation functions are measured for the first time in proton-proton collisions for charged pions, kaons, and protons within jets recoiling against a $Z$ boson. The charged-hadron distributions are studied longitudinally and transversely to the jet direction for jets with transverse momentum 20 $< p_{\textrm{T}} < 100$ GeV and in the pseudorapidity range $2.5 < \eta < 4$. The data sample was collected with the LHCb experiment at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 1.64 fb$^{-1}$. Triple differential distributions as a function of the hadron longitudinal momentum fraction, hadron transverse momentum, and jet transverse momentum are also measured for the first time. This helps constrain transverse-momentum-dependent fragmentation functions. Differences in the shapes and magnitudes of the measured distributions for the different hadron species provide insights into the hadronization process for jets predominantly initiated by light quarks.Comment: All figures and tables, along with machine-readable versions and any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-013.html (LHCb public pages

Study of the B−→Λc+Λˉc−K−B^{-} \to \Lambda_{c}^{+} \bar{\Lambda}_{c}^{-} K^{-} decay

The decay $B^{-} \to \Lambda_{c}^{+} \bar{\Lambda}_{c}^{-} K^{-}$ is studied in proton-proton collisions at a center-of-mass energy of $\sqrt{s}=13$ TeV using data corresponding to an integrated luminosity of 5 $\mathrm{fb}^{-1}$ collected by the LHCb experiment. In the $\Lambda_{c}^+ K^{-}$ system, the $\Xi_{c}(2930)^{0}$ state observed at the BaBar and Belle experiments is resolved into two narrower states, $\Xi_{c}(2923)^{0}$ and $\Xi_{c}(2939)^{0}$, whose masses and widths are measured to be $$m(\Xi_{c}(2923)^{0}) = 2924.5 \pm 0.4 \pm 1.1 \,\mathrm{MeV}, \\ m(\Xi_{c}(2939)^{0}) = 2938.5 \pm 0.9 \pm 2.3 \,\mathrm{MeV}, \\ \Gamma(\Xi_{c}(2923)^{0}) = \phantom{000}4.8 \pm 0.9 \pm 1.5 \,\mathrm{MeV},\\ \Gamma(\Xi_{c}(2939)^{0}) = \phantom{00}11.0 \pm 1.9 \pm 7.5 \,\mathrm{MeV},$$ where the first uncertainties are statistical and the second systematic. The results are consistent with a previous LHCb measurement using a prompt $\Lambda_{c}^{+} K^{-}$ sample. Evidence of a new $\Xi_{c}(2880)^{0}$ state is found with a local significance of $3.8\,\sigma$, whose mass and width are measured to be $2881.8 \pm 3.1 \pm 8.5\,\mathrm{MeV}$ and $12.4 \pm 5.3 \pm 5.8 \,\mathrm{MeV}$, respectively. In addition, evidence of a new decay mode $\Xi_{c}(2790)^{0} \to \Lambda_{c}^{+} K^{-}$ is found with a significance of $3.7\,\sigma$. The relative branching fraction of $B^{-} \to \Lambda_{c}^{+} \bar{\Lambda}_{c}^{-} K^{-}$ with respect to the $B^{-} \to D^{+} D^{-} K^{-}$ decay is measured to be $2.36 \pm 0.11 \pm 0.22 \pm 0.25$, where the first uncertainty is statistical, the second systematic and the third originates from the branching fractions of charm hadron decays.Comment: All figures and tables, along with any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-028.html (LHCb public pages

Measurement of the ratios of branching fractions R(D∗)\mathcal{R}(D^{*}) and R(D0)\mathcal{R}(D^{0})

The ratios of branching fractions $\mathcal{R}(D^{*})\equiv\mathcal{B}(\bar{B}\to D^{*}\tau^{-}\bar{\nu}_{\tau})/\mathcal{B}(\bar{B}\to D^{*}\mu^{-}\bar{\nu}_{\mu})$ and $\mathcal{R}(D^{0})\equiv\mathcal{B}(B^{-}\to D^{0}\tau^{-}\bar{\nu}_{\tau})/\mathcal{B}(B^{-}\to D^{0}\mu^{-}\bar{\nu}_{\mu})$ are measured, assuming isospin symmetry, using a sample of proton-proton collision data corresponding to 3.0 fb${ }^{-1}$ of integrated luminosity recorded by the LHCb experiment during 2011 and 2012. The tau lepton is identified in the decay mode $\tau^{-}\to\mu^{-}\nu_{\tau}\bar{\nu}_{\mu}$. The measured values are $\mathcal{R}(D^{*})=0.281\pm0.018\pm0.024$ and $\mathcal{R}(D^{0})=0.441\pm0.060\pm0.066$, where the first uncertainty is statistical and the second is systematic. The correlation between these measurements is $\rho=-0.43$. Results are consistent with the current average of these quantities and are at a combined 1.9 standard deviations from the predictions based on lepton flavor universality in the Standard Model.Comment: All figures and tables, along with any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-039.html (LHCb public pages

Observation of the B0 → ρ0ρ0 decay from an amplitude analysis of B0 → (π+π−)(π+π−) decays

Proton–proton collision data recorded in 2011 and 2012 by the LHCb experiment, corresponding to an integrated luminosity of 3.0 fb−1 , are analysed to search for the charmless B0→ρ0ρ0 decay. More than 600 B0→(π+π−)(π+π−) signal decays are selected and used to perform an amplitude analysis, under the assumption of no CP violation in the decay, from which the B0→ρ0ρ0 decay is observed for the first time with 7.1 standard deviations significance. The fraction of B0→ρ0ρ0 decays yielding a longitudinally polarised final state is measured to be fL=0.745−0.058+0.048(stat)±0.034(syst) . The B0→ρ0ρ0 branching fraction, using the B0→ϕK⁎(892)0 decay as reference, is also reported as B(B0→ρ0ρ0)=(0.94±0.17(stat)±0.09(syst)±0.06(BF))×10−6