Diffusion imaging and tractography of congenital brain malformations.

Diffusion imaging is an MRI modality that measures the microscopic molecular motion of water in order to investigate white matter microstructure. The modality has been used extensively in recent years to investigate the neuroanatomical basis of congenital brain malformations. We review the basic principles of diffusion imaging and of specific techniques, including diffusion tensor imaging (DTI) and high angular resolution diffusion imaging (HARDI). We show how DTI and HARDI, and their application to fiber tractography, has elucidated the aberrant connectivity underlying a number of congenital brain malformations. Finally, we discuss potential uses for diffusion imaging of developmental disorders in the clinical and research realms

Robustness of proxy-based climate field reconstruction methods

We present results from continued investigations into the fidelity of covariance-based climate field reconstruction (CFR) approaches used in proxy-based climate reconstruction. Our experiments employ synthetic “pseudoproxy” data derived from simulations of forced climate changes over the past millennium. Using networks of these pseudoproxy data, we investigate the sensitivity of CFR performance to signal-to-noise ratios, the noise spectrum, the spatial sampling of pseudoproxy locations, the statistical representation of predictors used, and the diagnostic used to quantify reconstruction skill. Our results reinforce previous conclusions that CFR methods, correctly implemented and applied to suitable networks of proxy data, should yield reliable reconstructions of past climate histories within estimated uncertainties. Our results also demonstrate the deleterious impact of a linear detrending procedure performed recently in certain CFR studies and illustrate flaws in some previously proposed metrics of reconstruction skill

Augmentative and Alternative Communication and digital participation

Communication is a basic need for all people to fully participate in life. Persons with disabilities may face particular challenges in developing their communication skills and using them appropriately in different situations. Augmentative and Alternative Communication (AAC) tools and methods can assist individuals in this process. Increasing digitization has changed the way everyone communicates, and this offers opportunities for persons using AAC. This paper briefly outlines what has been achieved in terms of digitalization in AAC. The need for full, adapted access to technology is highlighted and research desiderata are identified.Peer Reviewe

The New Global Corporate Culture: A Comparative Survey Of The Corporate Cultures Of Japan And The United States In The 21st Century

Japan 2007, is not the same country it was during theeighties, when foreigners flocked to Tokyo, armed with copies of books such as How to Succeed in Japan: A Business Etiquette Primer. Globalization, fueled by the Internet and other advances in communications technology, is playing an ever greater role in business operations around the globe. Outside of business, these advances allow people on opposite sides of the globe to interact, and this interaction exposes others to new ideas, views, languages, and cultures. This study evaluates the shifts in the corporate cultures of Japan and the United States, through the framework of Hofstedes value dimensions over the past 25 years, through the use of surveys and interviews in both countries. This rich material is backed by examples of these shifts in both countries; in addition to a brief overview of the communicative differences of Japan and the United States. This study will allow not only business professionals and managers, but also students and teachers, to approach another culture with clear, current insight that gets past stereotypes to help foster success in engaging and working with counterparts in other parts of the world

The deep imprint of Roman sandals : evidence of long-lasting effectsof Roman rule on personality, economic performance, and well-beingin Germany

We investigate whether the Roman presence in the southern part of Germany nearly 2,000 years ago had a deep imprinting effect with long run consequences on a broad spectrum of measures ranging from present-day personality profiles to a number of socioeconomic outcomes and why. Todays populations living in the former Roman part of Germany score indeed higher on certain personality traits, have higher life and health satisfaction, longer life expectancy, generate more inventions and behave in a more entrepreneurial way. These findings help explain that regions under Roman rule have higher present-day levels of economic development in terms of GDP per capita. The effects hold when controlling for other potential historical influences. When addressing potential channels of a long term effect of Roman rule the data indicates that the Roman road network plays an important role as a mechanism in the imprinting that is still perceptible today

Cultural Imprinting:Ancient Origins of Entrepreneurship and Innovation in Germany

A region’s present-day economic performance can be deeply anchored in historical factors. We provide the first systematic evidence of a deep imprinting effect in the context of Roman rule in the south-western part of Germany nearly 2,000 years ago. Our analysis reveals that regions in the former Roman part of Germany show a stronger entrepreneurship and innovation culture today, evident by higher levels of quantity and quality entrepreneurship and innovation. The data indicate that this lasting 'Roman effect' was constituted by the early establishment of interregional social and economic exchange and related infrastructure. Our findings thus help in unpacking the hidden cultural roots of present-day economic performance, with important implications for research and economic policy