Evidence-Based Health Care for Children: What Are We Missing?

Proposes a new framework for evaluating evidence in health care that takes into account interventions in child health promotion, which aim to change children's physical, social, or emotional environment and may take longer for the effects to show

CLIC Background Studies and optimization of the innermost tracker elements

The harsh machine background at the Compact Linear Collider (CLIC) forms a strong constraint on the design of the innermost part of the tracker. For the CLIC Conceptual Design Report, the detector concepts developed for the International Linear Collider (ILC) were adapted to the CLIC environment. We present the new layout for the Vertex Detector and the Forward Tracking Disks of the CLIC detector concepts, as well as the background levels in these detectors. We also study the dependence of the background rates on technology parameters like thickness of the active layer and detection threshold.Comment: 7 pages, 5 figures, LCWS 201

Development in a biologically inspired spinal neural network for movement control

In two phases, we develop neural network models of spinal circuitry which self-organises into networks with opponent channels for the control of an antagonistic muscle pair. The self-organisation is enabled by spontaneous activity present in the spinal cord. We show that after the process of self-organisation, the networks have developed the possibility to independently control the length and tension of the innerated muscles. This allows the specification of joint angle independent from the specification of joint stiffness. The first network comprises only motorneurons and inhibitory interneurons through which the two channels interact. The inhibitory interneurons prevent saturation of the motorneuron pools, which is a necessary condition for independent control. In the second network, however, the neurons in the motorneuron pools obey the size-principle, which is a threat to the desired invariance of joint angle for varying joint stiffness, because of the different amplification of inputs in the case these inputs are not equal. To restore the desired invariance the second network ha.s been expanded with Renshaw cells. The manner in which they are included in the circuitry corrects the problem caused by the addition of the size-principle. The results obtained from the two models compare favourably with the FLETE-model for spinal circuitry (Bullock & Grossberg, 1991; Bullock et al., HJ93; Bullock & Contreras-Vidal, 1993) which has been successful in explaining several phenomena related to motor control.Fulbright Scholarship; Office of Naval Research (N00014-92-J-1309, N00014-95-1-0409

Extracting the top-quark running mass using ttˉt\bar{t}+1-jet events produced at the Large Hadron Collider

We present the calculation of the next-to-leading order QCD corrections for top-quark pair production in association with an additional jet at hadron colliders, using the modified minimal subtraction scheme to renormalize the top-quark mass. The results are compared to measurements at the Large Hadron Collider run I. In particular, we determine the top-quark running mass from a fit of the theoretical results presented here to the LHC data

IAC user manual

The User Manual for the Integrated Analysis Capability (IAC) Level 1 system is presented. The IAC system currently supports the thermal, structures, controls and system dynamics technologies, and its development is influenced by the requirements for design/analysis of large space systems. The system has many features which make it applicable to general problems in engineering, and to management of data and software. Information includes basic IAC operation, executive commands, modules, solution paths, data organization and storage, IAC utilities, and module implementation

Top quark precision physics at the International Linear Collider

Top quark production in the process $e^+e^- \rightarrow t\bar{t}$ at a future linear electron positron collider with polarized beams is a powerful tool to determine the scale of new physics. Studies at the \ttbar threshold will allow for precise determination of the top quark mass in a well defined theoretical framework. At higher energies vector, axial vector and tensorial CP conserving couplings can be separately determined for the photon and the $Z^0$ component in the electro-weak production process. The sensitivity to new physics would be dramatically improved w.r.t. to what expected from LHC for electroweak couplings.Comment: White paper for Snowmass CSS 201

Septic Arthritis Caused by Legionella dumoffii in a Patient with Systemic Lupus Erythematosus-Like Disease

We describe a patient with systemic lupus erythematosus (SLE)-like disease on immunosuppressive treatment who developed septic arthritis of the knee involving Legionella dumoffii. Cultures initially remained negative. A broad-range 16S PCR using synovial fluid revealed L. dumoffii rRNA genes, a finding that was subsequently confirmed by positive Legionella culture results

Modulating active sites in MOFs for improved Lewis acid or base catalysis

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