Limits to the critical current in Bi2Sr2Ca2Cu3Ox tape conductors: The parallel path model

An extensive overview of a model that describes current flow and dissipation in high-quality Bi2Sr2Ca2Cu3Ox superconducting tapes is provided. The parallel path model is based on a superconducting current running in two distinct parallel paths. One of the current paths is formed by grains that are connected at angles below 4°. Dissipation in this strongly linked backbone occurs within the grains and is well described by classical flux-creep theory. The other current path, the weakly linked network, is formed by superconducting grains that are connected at intermediate angles (4°–8°) where dissipation occurs at the grain boundaries. However, grain boundary dissipation in this weakly linked current path does not occur through Josephson weak links, but just as in the strongly linked backbone, is well described by classical flux creep. The results of several experiments on Bi2Sr2Ca2Cu3Ox tapes and single-grained powders that strongly support the parallel path model are presented. The critical current density of Bi2Sr2Ca2Cu3Ox tapes can be scaled as a function of magnetic field angle over the temperature range from 15 K to 77 K. Expressions based on classical flux creep are introduced to describe the dependence of the critical current density of Bi2Sr2Ca2Cu3Ox tapes on the magnetic field and temperature

In vitro plant regeneration and Agrobacterium tumefaciens-mediated transformation of Datura stramonium (Solanaceae).

Premise of the Study:Datura stramonium is a pharmacologically and evolutionarily important plant species in the family Solanaceae. Stable transformation methodology of this species would be advantageous for future genetic studies. Methods:In vitro plant regeneration and Agrobacterium tumefaciens-mediated transformation techniques were developed for D. stramonium based on methods reported for tomato. A binary vector containing pAtUBQ10::erGFP was used for transformation. Results:We recovered primary transformants harboring the green fluorescent protein (GFP) transgene that resulted in expression of fluorescence in all tissues analyzed. Transformants were allowed to self-pollinate, and two of five progeny contained the GFP transgene and displayed fluorescence identical to the primary transformants. Discussion:We have demonstrated the first stable transformation in the genus Datura. This is a key first step to study the genetic basis of traits in this evolutionarily interesting species

Tomography of the red supergiant star {\mu} Cep

A tomographic method, aiming at probing velocity fields at depth in stellar atmospheres, is applied to the red supergiant star {\mu} Cep and to snapshots of 3D radiative-hydrodynamics simulation in order to constrain atmospheric motions and relate them to photometric variability.Comment: 2 pages, 2 figures, accepted as Proceedings of IAU Symposium No. 343, 201

A survey of the hoverflies of northeastern Algeria (Diptera: Syrphidae)

A survey of the hoverfly fauna of northeastern Algeria was carried out in 1991 and 1992, and seventy-three species recorded. Four species are new for Algeria: Dasysyrphus albostriatus, Chamaesyrphus lusitanicus, Brachypalpus laphriformis and Spilomyia maroccana. The genera Dasysyrphus, Chamaesyrphus and Brachypalpus are new for Algeria. Data on the distribution and the seasonal pattern of each species are provided. Species richness was found highest amongst wetlands (up to 38) and forested hills (up to 29). In contrast, degraded sites held the lowest numbers of hoverflies. Species such as Episyrphus balteatus, Sphaerophoria scripta, Syritta pipiens and Eristalis tenax were widespread and abundant, whereas others were rare (Platycheirus albimanus) or confined to forested hills, such as the North African endemic Volucella liquida. A good knowledge of the Syrphidae will pave the way to a close monitoring of global changes affecting the region and the conservation of an important but much neglected group in one of the foremost biodiversity hotspots of the Maghreb.Keywords: Syrphids, distribution, biodiversity, conservation, Algeria

A holistic approach to carbon-enhanced metal-poor stars

By considering the various CEMP subclasses separately, we try to derive, from the specific signatures imprinted on the abundances, parameters (such as metallicity, mass, temperature, and neutron source) characterizing AGB nucleosynthesis from the specific signatures imprinted on the abundances, and separate them from the impact of thermohaline mixing, first dredge-up, and dilution associated with the mass transfer from the companion.To put CEMP stars in a broad context, we collect abundances for about 180 stars of various metallicities, luminosity classes, and abundance patterns, from our own sample and from literature. First, we show that there are CEMP stars which share the properties of CEMP-s stars and CEMP-no stars (which we call CEMP-low-s stars). We also show that there is a strong correlation between Ba and C abundances in the s-only CEMP stars. This strongly points at the operation of the 13C neutron source in low-mass AGB stars. For the CEMP-rs stars (seemingly enriched with elements from both the s- and r-processes), the correlation of the N abundances with abundances of heavy elements from the 2nd and 3rd s-process peaks bears instead the signature of the 22Ne neutron source. Adding the fact that CEMP-rs stars exhibit O and Mg enhancements, we conclude that extremely hot conditions prevailed during the thermal pulses of the contaminating AGB stars. Finally, we argue that most CEMP-no stars (with no overabundances for the neutron-capture elements) are likely the extremely metal-poor counterparts of CEMP neutron-capture-rich stars. We also show that the C enhancement in CEMP-no stars declines with metallicity at extremely low metallicity ([Fe/H]~< -3.2). This trend is not predicted by any of the current AGB models.Comment: 27 pages, 24 figures, accepted for publication in A&

The temperature and chronology of heavy-element synthesis in low-mass stars

Roughly half of the heavy elements (atomic mass greater than that of iron) are believed to be synthesized in the late evolutionary stages of stars with masses between 0.8 and 8 solar masses. Deep inside the star, nuclei (mainly iron) capture neutrons and progressively build up (through the slow-neutron-capture process, or s-process) heavier elements that are subsequently brought to the stellar surface by convection. Two neutron sources, activated at distinct temperatures, have been proposed: 13C and 22Ne, each releasing one neutron per alpha-particle (4He) captured. To explain the measured stellar abundances, stellar evolution models invoking the 13C neutron source (which operates at temperatures of about one hundred million kelvin) are favoured. Isotopic ratios in primitive meteorites, however, reflecting nucleosynthesis in the previous generations of stars that contributed material to the Solar System, point to higher temperatures (more than three hundred million kelvin), requiring at least a late activation of 22Ne. Here we report a determination of the s-process temperature directly in evolved low-mass giant stars, using zirconium and niobium abundances, independently of stellar evolution models. The derived temperature supports 13C as the s-process neutron source. The radioactive pair 93Zr-93Nb used to estimate the s-process temperature also provides, together with the pair 99Tc-99Ru, chronometric information on the time elapsed since the start of the s-process, which we determine to be one million to three million years.Comment: 30 pages, 10 figure

Simulating the impact of tax incentives using a type choice model for lease cars

Tax incentives for hybrid and electric cars are one of the possible policy instruments to reduce the CO2 emissions of cars. This paper looks at the impacts of this policy in the context of The Netherlands, where up to 2016 substantial tax incentives were provided to fuel efficient lease cars, especially for hybrid and electric lease cars. For this analysis this paper uses a new model of vehicle type choice. Existing models for the choice among car type alternatives either exclude electric and hybrid cars or are based on stated preference data. In both cases, the models usually focus on privately-owned cars. The car type choice model for lease cars, that is used in this paper, includes electric and hybrid alternatives and is estimated on revealed preference data from lease car users in The Netherlands. Simulations with this model show that the tax incentives provided over the period 2011–2016 have led to a reduction in CO2 emissions of lease cars, but also to an increase in the share of diesel cars and local air pollution

Hematopoietic arginase 1 deficiency results in decreased leukocytosis and increased foam cell formation but does not affect atherosclerosis

Background and aimsArginase1 (Arg1), an M2 macrophage marker, plays a critical role in a number of immunological functions in macrophages, which are the main cell type facilitating atherosclerotic lesion development. Arg1 uses the substrate l-arginine to create l-ornithine, a precursor molecule required for collagen formation and vascular smooth muscle cell differentiation. By reducing l-arginine availability, Arg1 limits the production of nitric oxide (NO), a pro-atherogenic factor in macrophages. In endothelial cells, conversely, NO is strongly anti-atherogenic. However, until now, the role of Arg1 in atherosclerosis is largely unknown. The aim of this study is to specifically investigate the effect of Arg1 deletion in hematopoietic cells on atherosclerosis susceptibility.MethodsLdlr KO mice were transplanted with Arg1flox/flox;Tie2-Cre (Arg1 KO) bone marrow (BM) or wildtype (WT) BM. After 8 weeks of recovery on chow diet, recipients mice were fed a Western-Type Diet (WTD) for 10 weeks to induce atherosclerosis.ResultsAfter 10-week WTD challenge, blood leukocyte counts were decreased by 25% (p p = 0.05) in Ldlr KO mice transplanted with Arg1 KO BM compared to mice transplanted with WT BM. The decrease in leukocytes was due to lower B lymphocyte counts. However, oxLDL-specific antibodies were increased in plasma of Ldlr KO mice transplanted with Arg1 KO BM compared to WT BM transplanted controls, whereas oxLDL-specific IgM was not affected. On the other hand, peritoneal foam cells in Arg1 KO BM recipients were increased 3-fold (p ConclusionsDeletion of Arg1 in hematopoietic cells adversely affects blood leukocyte counts and increases foam cell formation. However, no effects on atherosclerosis could be demonstrated, indicating that hematopoietic Arg1 function is not a decisive factor in atherosclerotic plaque formation.Article / Letter to editorLeiden Academic Centre for Drug Researc

Hematopoietic arginase 1 deficiency results in decreased leukocytosis and increased foam cell formation but does not affect atherosclerosis

Background and aimsArginase1 (Arg1), an M2 macrophage marker, plays a critical role in a number of immunological functions in macrophages, which are the main cell type facilitating atherosclerotic lesion development. Arg1 uses the substrate l-arginine to create l-ornithine, a precursor molecule required for collagen formation and vascular smooth muscle cell differentiation. By reducing l-arginine availability, Arg1 limits the production of nitric oxide (NO), a pro-atherogenic factor in macrophages. In endothelial cells, conversely, NO is strongly anti-atherogenic. However, until now, the role of Arg1 in atherosclerosis is largely unknown. The aim of this study is to specifically investigate the effect of Arg1 deletion in hematopoietic cells on atherosclerosis susceptibility.MethodsLdlr KO mice were transplanted with Arg1flox/flox;Tie2-Cre (Arg1 KO) bone marrow (BM) or wildtype (WT) BM. After 8 weeks of recovery on chow diet, recipients mice were fed a Western-Type Diet (WTD) for 10 weeks to induce atherosclerosis.ResultsAfter 10-week WTD challenge, blood leukocyte counts were decreased by 25% (p p = 0.05) in Ldlr KO mice transplanted with Arg1 KO BM compared to mice transplanted with WT BM. The decrease in leukocytes was due to lower B lymphocyte counts. However, oxLDL-specific antibodies were increased in plasma of Ldlr KO mice transplanted with Arg1 KO BM compared to WT BM transplanted controls, whereas oxLDL-specific IgM was not affected. On the other hand, peritoneal foam cells in Arg1 KO BM recipients were increased 3-fold (p ConclusionsDeletion of Arg1 in hematopoietic cells adversely affects blood leukocyte counts and increases foam cell formation. However, no effects on atherosclerosis could be demonstrated, indicating that hematopoietic Arg1 function is not a decisive factor in atherosclerotic plaque formation.Article / Letter to editorLeiden Academic Centre for Drug Researc