433 research outputs found
How Do They Do It? A Phenomenological Description of Stress and Coping in Radiation Therapists
This study aimed to better understand and describe the lived experiences of job-related stressors and associated coping mechanisms of radiation therapists (RTTs). The study employed a phenomenological qualitative method as to explore the experiences of 11 radiation therapists in select regional cancer centers in the Southeastern United States. The following questions were explored: (a) How do radiation therapists describe job-related stress? (b) What factors do radiation therapists identify as contributing to job-related stress? (c) What mechanisms do radiation therapists employ to cope with job-related stress they described? and (d) How do radiation therapists find motivation to continue in their chosen field in light of job-related stress? The data collection process included individual interviews, online focus groups, and personal journaling by the participants, whom were chosen through purposeful sampling. Data analysis was conducted via a hermeneutic interpretive approach following a systematic analytical guide as detailed by previous qualitative researchers. Findings suggested that the radiation therapists experience substantial stress in their work situations, which they most often attributed to uncontrollable situations, and they struggled with methods of coping, likely choosing to work through stressful situations in lieu of coping. The radiation therapists found intense motivation in their relationships with their patients, crediting them with the reasons for continuation in their careers
Perceptual Differences in School Climate Between Administrators and Teachers within Christian Schools
School climate has been researched for the past 100 years. However, there is a lack of school climate research focused on perceptual differences between school leaders and teachers. It is important to evaluate stakeholder differences, as principals are tasked with forming the climate of the school and teachers are responsible for relaying that climate to students. Furthermore, there is a lack of school climate studies conducted in private Christian schools. Christian school leaders need school climate data to help sustain and improve Christian education. The purpose of this causal comparative study is to evaluate perceptual differences between administrators and teachers in Christian schools in the southeast region of the United States. The participants were chosen from a convenience sample of high school teachers and administrators from Association of Christian Schools International (ACSI) member schools in the southeast region of the United States (N=50 teachers and N=50 administrators). The participants received an email requesting them to complete a survey by clicking on the survey link and responding to the questions. Data was collected from participants’ responses to the revised School-Level Environment Questionnaire (r-SLEQ). Multivariate analysis of variance (MANOVA) was used to determine if perceptual differences exist between teachers and administrators. The data analysis produced three significant findings. There were statistically significant differences in the overall school climate domain, the decision-making domain, and the school resources domain. This study reveals the specific areas in which Christian school educators should focus their attention in order to improve their school climate. Recommendations for further research include replicating this study in additional Christian school regions to increase generalizability
Organic parasite control for poultry and rabbits in British Columbia, Canada
Plants used for treating endo- and ectoparasites of rabbits and poultry in British Columbia included Arctium lappa (burdock), Artemisia sp. (wormwood), Chenopodium album (lambsquarters) and C. ambrosioides (epazote), Cirsium arvense (Canada thistle), Juniperus spp. (juniper), Mentha piperita (peppermint), Nicotiana sp. (tobacco), Papaver somniferum (opium poppy), Rubus spp. (blackberry and raspberry relatives), Symphytum officinale (comfrey), Taraxacum officinale (common dandelion), Thuja plicata (western redcedar) and Urtica dioica (stinging nettle)
Homocysteine concentrations in the cognitive progression of Alzheimer’s disease
Objectives: Hyperhomocysteinemia in Alzheimer’s disease (AD) is widely reported and appears to worsen as the disease progresses. While active dietary intervention with vitamins B12 and folate decreases homocysteine blood levels, with promising clinical outcomes in Mild Cognitive Impairment (MCI), this so far has not been replicated in established AD populations. The aim of the study is to explore the relationship between hyperhomocystenemia and relevant vitamins as the disease progresses.
Methods: In this longitudinal cohort study, 38 participants with mild to moderate AD were followed for an average period of 13 months. Plasma folate, vitamin B12 and homocysteine concentrations were measured at baseline and at follow-up. Dietary intake of B vitamins was also measured. Spearman’s correlations were conducted by homocysteine and B vitamin status.
Results: As expected, cognitive status significantly declined over the follow-up period and this was paralleled by a significant increase in homocysteine concentrations (p=0.006). However, during this follow-up period there was no significant decline in neither dietary intake, nor the corresponding blood concentrations of vitamin B12/folate, with both remaining within normal values. Changes in blood concentrations of B vitamins were not associated with changes in homocysteine levels (p>0.05).
Conclusion: In this study, the increase in homocysteine observed in AD patients as the disease progresses cannot be solely explained by dietary and blood levels of folate and vitamin B12. Other dietary and non-dietary factors may contribute to hyperhomocysteinemia and its toxic effect in AD, which needs to be explored to optimise timely intervention strategies
Ethnoveterinary medicines used for horses in Trinidad and in British Columbia, Canada
This paper investigates the commonalities in ethnoveterinary medicine used for horses between Trinidad (West Indies) and British Columbia (Canada). These research areas are part of a common market in pharmaceuticals and are both involved in the North American racing circuit. There has been very little research conducted on medicinal plants used for horses although their use is widespread. The data on ethnoveterinary medicines used for horses was obtained through key informant interviews with horse owners, trainers, breeders, jockeys, grooms and animal care specialists in two research areas: Trinidad and British Columbia (BC). A participatory validation workshop was held in BC. An extensive literature review and botanical identification of the plants was also done. In all, 20 plants were found to be used in treating racehorses in Trinidad and 97 in BC. Of these the most-evidently effective plants 19 of the plants used in Trinidad and 66 of those used in BC are described and evaluated in this paper. Aloe vera, Curcuma longa and Ricinus communis are used in both research areas. More research is needed in Trinidad to identify plants that respondents claimed were used in the past. Far more studies have been conducted on the temperate and Chinese medicinal plants used in BC and therefore these ethnoveterinary remedies reflect stronger evidence of efficacy
Perceptions of Five Middle School Science Teachers: A Suburban Success Story on the Texas Assessment of Knowledge and Skills Achievement for Eighth Grade African American Students
The purpose of this qualitative study was to examine a problem of practice present in an actual school district. The study examined the achievement gap that existed between African American and European American students in eighth grade science. Over the course of one school year, the perceptions of five eighth grade science teachers and an administrative team’s series of strategies were explored in a suburban middle school in Southeast Texas.
Since the enactment of the federal No Child Left Behind Act (2001), the achievement gap has been discussed and studied. However, few studies have investigated the strategies used by teachers to close the achievement gap for African American students who attend suburban schools.
This study examined the perceptions of five science teachers about the achievement gap at one suburban middle school, and identified and described the teaching methods and practices, aimed at closing the achievement gap as measured by the performance of African American students on the eighth grade Science Texas Assessment of Knowledge and Skills (TAKS) test. Participants were the eighth grade science teachers at the chosen school. The results yielded a reduction in the achievement gap for African American students in eighth grade science on the Texas Assessment of Knowledge and Skills; 90% of the African American students passed the Science TAKS test in comparison to the 77% pass rate the previous school year. Member checking and peer debriefing were used to establish trustworthiness.
Recommendations for future study include a comparison of culturally responsive teaching and Quantum Learning (2008) strategies, as well as areplication of the identified strategies in the study to other suburban and urban schools, and districts
Biclustering models for structured microarray data
©2005 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE.Microarrays have become a standard tool for investigating gene function and more complex microarray experiments are increasingly being conducted. For example, an experiment may involve samples from several groups or may investigate changes in gene expression over time for several subjects, leading to large three-way data sets. In response to this increase in data complexity, we propose some extensions to the plaid model, a biclustering method developed for the analysis of gene expression data. This model-based method lends itself to the incorporation of any additional structure such as external grouping or repeated measures. We describe how the extended models may be fitted and illustrate their use on real data
Housing, income support and mental health: Points of disconnection
There exists a disconnection between evolving policies in the policy arenas of mental health, housing, and income support in Canada. One of the complexities associated with analysing the intersection of these policies is that federal, provincial, and municipal level policies are involved. Canada is one of the few developed countries without a national mental health policy and because of the federal policy reforms of the 1970s, the provincial governments now oversee the process of deinstitutionalization from the hospital to the community level. During this same period the availability of affordable housing has decreased as responsibility for social housing has been transfered from the federal government to the provincial and/or municipal levels of government. Canada also stands alone in terms of being a developed nation without national housing policy instead what is considered "affordable" housing is partially dependant upon individuals' personal economic resources. As well, over the past decade rates of income supports have also been reduced. Psychiatric survivors have long been identified as being at risk for homelessness, with the disconnection existing between housing, income and mental health policies and the lack of a national policy in any of these policies areas further contributing to this risk
Multimedia Open Educational Resource Materials for Teaching-Online Diversity and Leadership: Aligning Bloom’s Taxonomy and Studio Habits of Mind
Objective: The purpose of this study was to explore, develop, test, and refine processes to incorporate meaningful and equitable use of open educational resources (OER) in online classrooms.
Method: The intent of this qualitative study was to use an action research process of interactive discussions between higher education practitioners to shape collective understanding of how to teach in an online learning environment using OER.
Results: The study resulted in the identification six exemplar learning opportunities which could be incorporated into the blended pedagogical model. Each exemplar OER included all four types of knowledge as defined by Bloom\u27s taxonomy and required skills of observe and envision as defined in the Studio Habits of Mind (SHoM). A second criteria for our purposive selection was that each exemplar could be used to teach in multiple contexts for multiple purposes across a spectrum of higher education online courses.
Conclusion: This study reminds us that educators need a new mindset to work with multimedia and visual resources. The blended pedagogical model provides scaffold teaching and learning opportunities that were not visible in either Bloom\u27s taxonomy or SHoM alone. This blended pedagogical model scaffolds the “how” when using a visual approach to curriculum development that may enrich the learning experiences of students when presented in online higher education classrooms.
Implication for Practice: Educators might replicate this study or transfer findings for purposes of comparing and testing further the use of OER in their online higher education classes to further engage student learning. Applying new understanding in a project that is shared with the larger learning group is essential as students understand and begin to own new skills and insights. The blended pedagogical model presented in this paper could be helpful to educators to maximize the benefits from the integration of technology and OERs to support online higher education
Xenoestrogen-Induced ERK-1 and ERK-2 Activation via Multiple Membrane-Initiated Signaling Pathways
Xenoestrogens can mimic or antagonize the activity of physiological estrogens, and the suggested mechanism of xenoestrogen action involves binding to estrogen receptors (ERs). However, the failure of various in vitro or in vivo assays to show strong genomic activity of xenoestrogens compared with estradiol (E(2)) makes it difficult to explain their ability to cause abnormalities in animal (and perhaps human) reproductive functions via this pathway of steroid action. E(2) has also been shown to initiate rapid intracellular signaling, such as changes in levels of intracellular calcium, cAMP, and nitric oxide, and activations of a variety of kinases, via action at the membrane. In this study, we demonstrate that several xenoestrogens can rapidly activate extracellular-regulated kinases (ERKs) in the pituitary tumor cell line GH(3)/B6/F10, which expresses high levels of the membrane receptor for ER-α(mER). We tested a phytoestrogen (coumestrol), organochlorine pesticides or their metabolites (endosulfan, dieldrin, and DDE), and detergent by-products of plastics manufacturing (p-nonylphenol and bisphenol A). These xenoestrogens (except bisphenol A) produced rapid (3–30 min after application), concentration (10(−14)–10(−8) M)-dependent ERK-1/2 phosphorylation but with distinctly different activation patterns. To identify signaling pathways involved in ERK activation, we used specific inhibitors of ERs, epidermal growth factor receptors, Ca(2+) signaling, Src and phosphoinositide-3 kinases, and a membrane structure disruption agent. Multiple inhibitors blocked ERK activation, suggesting simultaneous use of multiple pathways and complex signaling web interactions. However, inhibitors differentially affected each xenoestrogen response examined. These actions may help to explain the distinct abilities of xenoestrogens to disrupt reproductive functions at low concentrations
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