THE EFFECT OF 8-WEEK EXERCISE PROGRAM ON SOME HEMATOLOGICAL PARAMETERS IN OBESE CHILDREN

The aim of this study was to investigate the effects of eight weeks exercise program on some hematological parameters in obese and overweight children. A total of 44 boys aged 14-16 were included in the study. The obese group was divided into two groups as 22, and overweight group 22. Body mass index (BMI) values were used to determine obesity in the formation of groups. The children who participated in the study were selected activities according to the branches which lasted 60 minutes in 3 days a week for 3 weeks and the walking program was increased. Blood samples taken at rest and at the end of the study; WBC (leukocyte), RBC (erythrocyte), hemoglobin (HGB), hematocrit (HCT), platelet (PLT), mean platelet volume (MPV) and platelet distribution width (PDW) levels were analyzed. SPSS 22.0 statistical program (SPSS Inc., Chicago, Illinois, USA) was used for the statistical analysis of the data. Independent Samples T test for comparison of binary groups; Paired Samples T tests were used to analyze the difference between pre-test and post-test groups. At the end of the exercise, statistically significant differences were found in body weight, MCV, MPV and PDW values between the pre-test and post-test of the measured values of obese subjects (p <0.05). The body weight, BMI, RBC, HGB, HCT, MPV and PDW values of the overweight group were statistically significant (p<0.05). There was no significant difference between the groups in obese and overweight groups (p>0.05). As a result, it can be said that the obese and overweight group caused changes in hematological parameters and the overweight group was more likely to be affected by the exercise than the obese group.  Article visualizations

The relationship between some physical fitness characteristics and body composition of elite wrestlers

The aim of present study was to investigate the relationship between elite wrestlers' body composition and static strength, anaerobic power and static balance characteristics. Eleven elite male freestyle wrestlers (age = 18.8 ± 1.1 years, height = 170.9 ± 5.3 cm, weight = 75.2 ± 9.6 kg, BMI = 25.7 ± 2.4 kg/m2) who struggle in Turkish Wrestling Super League from Bursa Metropolitan Municipality Sports Club, voluntary participated. Subjects’ height, weight, body composition, balance (Peri Length 443.1 ± 140.6 cm, Aria Gap P 20.6 ± 12.9 cm), anaerobic power (106.3 ± 16.8 kg/m/sec), back strength (140.2 ± 30.7 kg) and grip strength (47.6 ± 6.4 kg) test were measured. Pearson correlation coefficient were performed to determine the relationship between variables. In conclusion, anaerobic power, strength and balance are related to body composition components such as height, body weight, BMI, arm and leg fat %, muscle mass and body weight

Magnetically Levitated Microrobotic Mixer

Microfluidic systems, when combined with microrobots, offer enhanced precision in chemical synthesis by precisely controlling reaction conditions. These systems, when integrated with analytical tools, allow for real-time monitoring and are cost-efficient due to their minimal volume requirements, thereby reducing risks associated with hazardous chemicals. In our study, we have investigated the mixing efficiency of Thymolphthalein indicator with NaOH solution in a magnetically levitated microrobotic mixer. A PMMA microfluidic chip was used to transfer fluid containing two different solutions and achieve fast and efficient mixing. By adjusting five different flow rates and altering the rotational speeds of the microrobots, the mixing efficiency was observed. The studies were carried out under the laminar regime, with incompressible Newtonian flow rates and varying actuator speeds. The measurement of mixing efficiency was accomplished through the calculation of changes in pixel intensity observed in microscopic images acquired throughout the mixing process. The presence of the microrobots resulted in the best efficiency at 80.37% at 500 rpm and 7 mL/min flow rate. Their potential in advanced reactions, such as nanoparticle synthesis and encapsulation, suggests promising avenues for improving product yields.Comment: 5 pages, 2 figures, 1 tabl

B-mode ultrasound assessment of carotid artery structural features in patients with normocalcaemic hyperparathyroidism

Introduction: Normocalcaemic hyperparathyroidism is a condition first defined in 2008, characterized by normal se- rum calcium and high parathormone levels. Although normocalcaemic hyperparathyroidism is considered to have a milder clinical picture compared to asymptomatic primary hyperparathyroidism, recent studies have shown that it may be associated with osteoporosis, insulin resistance, metabolic syndrome, and cardiovascular risk factors. Considering that normo- calcaemic hyperparathyroidism may pose a cardiovascular risk in the setting of carotid atherosclerosis, we sought to examine the structural features of the carotid artery in patients with normocalcaemic hyperparathyroidism compared to a control group. Material and Methods: After excluding patients with hypertension, diabetes, and dyslipidaemia (other factors contributing to atheroscle- rosis), 37 (32 females, 5 males) patients with normocalcaemic hyperparathyroidism with a mean age of 51.2 +/- 8 (min: 32, max: 66) years and 40 controls (31 females, 9 males) with a mean age of 49.3 +/- 7.5 (min: 34, max: 64) years with normal serum albumin-corrected calcium and parathyroid hormone levels were included in the study. Structural features of the carotid artery including intima-media thickness (mean and maximum), lumen diameter, and the presence of plaque were assessed using B-mode ultrasound. Results: On ANCOVA analysis corrected for atherosclerotic factors (body mass index, waist circumference, fasting plasma glucose, serum cholesterol, lipid, and blood pressure), greater mean intima-media thickness was found in patients with normocalcaemic hyperparathyroidism than in controls (0.65 mm vs. 0.59 mm, respectively) (p = 0.023). Maximum ca- rotid intima-media thickness was also greater in patients with normocalcaemic hyperparathyroidism compared to controls (0.80 mm vs. 0.75 mm, respectively) (p = 0.044). The study groups did not show a significant difference in lumen diameter and the presence of carotid plaque. In addition, a negative correlation was found between parathormone (PTH) level and lumen diameter. Conclusion: The findings of this study show that as with asymptomatic primary hyperparathyroidism, normocalcaemic hyperparathy- roidism may be associated with increased cardiovascular risk by predisposing to atherosclerosis. (Endokrynol Pol 2023; 74 (1): 67-73

Hypophosphatasia Presenting with Pyridoxine-Responsive Seizures, Hypercalcemia, and Pseudotumor Cerebri: Case Report

Hypophosphatasia (HPP) is an inborn error of metabolism characterized by defective bone mineralization caused by a deficiency in alkaline phosphatase (ALP) activity due to mutations in the tissue-nonspecific ALP (TNALP) gene. The clinical expression of the disease is variable. Six forms of HPP are identified according to age at presentation and clinical features. Patients with the infantile form are normal at birth. First symptoms appear within the first 6 months of life. Along with skeletal findings, HPP patients may present with hypercalcemia, seizures, pseudotumor cerebri, and pulmonary insufficiency. Seizures in HPP are refractory to conventional antiepileptic drugs, but are responsive to pyridoxine. Herein, we report a case of HPP who presented with pyridoxine-responsive seizures in the early neonatal period and was found to have hypercalcemia, skeletal demineralization and increased intracranial pressure. Key words: Hypophosphatasia, pyridoxine-responsive seizures, bisphosphonates, alkaline phosphatase, bone resorption, hypercalcemi

Comparison of muscle activation during push-ups exercise on stable and unstable surfaces

Bu çalışmada, instabilite cihazlarında ve sabit zeminde yapılan şınav egzersizi sırasında Pectoralis Majör (PM), Antreior Deltoid (AD) ve Triceps Brachii (TB) kaslarının elektromiyografik aktivasyonlarının belirlenmesi amaçlanmıştır. 18-25 yaş aralığında 25 katılımcı, sabit bir yüzey, her iki taraf da kullanılan top (BOSU), Pilates topu ve Fonksiyonel egzersiz bandı (TRX) üzerinde çapraz geçişli deney tasarımında şınav egzersizi uyguladı. Katılımcılar 2 saniye iniş, 2 saniye çıkış fazı olmak üzere 3 tekrardan oluşan şınav hareketini sırasıyla 4 zeminde uyguladı. Egzersiz sırasında PM, AD ve TB kaslarının amplitüdünü belirlemek için yüzey elektromiyografisi (sEMG) kullanıldı. sEMG genliği, kasların izometrik kasılmaları sırasında en yüksek tepe tork değerini veren maksimum istemli kasılma (MİK) yöntemi kullanılarak normalleştirildi. PM kasında TRX’te sabit zemin ve BOSU’ya göre önemli ölçüde daha yüksek normalize sEMG amplitüdü (%MİK) değerleri tespit edildi. AD kasında Pilates topunda diğer zeminlere göre önemli ölçüde daha düşük %MİK değerleri tespit edildi. TB kasında sabit yüzey ve BOSU’ya kıyasla TRX ve Pilates topunda önemli ölçüde daha yüksek %MİK değerleri tespit edilirken BOSU’da sabit zemine göre daha yüksek değerler tespit edildi. TRX’te şınav PM, AD, TB kasları için daha fazla zorluk isteyen antrenörler için iyi bir seçenek olabilirken; AD kası için şınav egzersizinde pilates topunu tercih etmek doğru olmayabilir.In this study, it was aimed to determine the electromyographic activations of Pectoralis Major (PM), Anterior Deltoid (AD), and Triceps Brachii (TB) muscles during push-up exercises performed on instability devices and a stable surface. Twenty-five participants aged 18-25 performed push-ups in an experimental crossover design on a stable surface, both sides utilized ball (BOSU), Pilates ball, and TRX Suspension Trainer (TRX). Participants completed the push-up exercise consisting of 3 repetitions, 2 seconds of descent, and 2 seconds of ascent, on four floors, respectively. Surface electromyography (sEMG) was used to determine the amplitude of the PM, AD, and TB muscles during exercise. The sEMG amplitude was normalized using the maximum voluntary contraction (MİK) method, which gives the highest peak torque value during isometric contractions of the muscles. Significantly higher normalized sEMG amplitude (%MİK) values were detected in the PM muscle compared to the stable surface and BOSU in TRX. In the AD muscle, significantly lower %MİK values were detected on the Swiss Ball compared to the other surfaces. Compared to the stable surface and BOSU in the TB muscle, significantly higher %MİK values were detected in the TRX and Swiss Ball, while higher values were detected in the BOSU than in the stable surface. While TRX can be a good option for trainers who want more challenge for the PM, AD, and TB muscles, It may not be suitable to prefer the Swiss Ball in push-up exercise for AD muscle

Acute effects of different types of exercises on insulin-like growth factor-1, homocysteine and cortisol levels in veteran athletes

This study aimed to investigate acute effects of table tennis(physical+cognitive exercise), aerobic running (physical exercise), and chess (cognitive exercise) exercise sessions of veteran male athletes in their branches on the serum homocysteine (Hcy), insulin growth factor-1 (IGF-1), and cortisol (Cor) levels. Thirty veteran athletes [10 table tennis players (TT), 10 long-distance runners (LR), 10 chess players (CP)] and 10 sedentary controls (SC) between 50 and 65 years of age participated in the study. Blood samples were obtained before and immediately after exercise to determine serum Hcy, IGF-1, and Cor levels. According to their branch, each veteran athlete performed exercise sessions (70-75% of the participants' heart rate reserve) of 10-min of warm-up followed by 40-min of table tennis, aerobic running, or chess. TT and LR groups demonstrated significant increases in the serum IGF-1, Cor, and Hcy levels from pre to post-exercise (p0.05). LR group had a greater serum Cor increase than all exercise groups (p<0.05). The TT group showed significantly greater changes in serum Cor levels than the CP group (p<0.05). In conclusion, although a single bout of aerobic running and table tennis exercise induces a remarkable increase in all measured biomarkers, chess exercise only elicits an increase in Hcy levels. Although aerobic running is more effective in increasing Cor levels than other types of exercise, the current study's findings suggest that serum Hcy and IGF-1 levels in veteran male athletes are not affected by the type of exercise

Acute effects of different warm-up protocols on athlete's performance

Bu araştırmanın amacı, farklı ısınma protokollerinin elit sporcuların performansı üzerine akut etkilerinin incelenmesidir. Materyal ve Metot: Araştırmanın denek grubu, Uludağ Üniversitesi Spor Bilimleri Fakültesi'nde eğitim hayatına devam eden ve çeşitli liglerde en az yedi yıldır futbol oynayan ve son altı ay içerisinde herhangi bir sakatlık geçirmemiş (ortalama boy 175.30 ± 6.59 cm, yaş 21.35 ± 1.66 yıl ve vücut ağırlığı 66.66 ± 7.49 kg) olan 20 erkek gönüllü öğrenciden oluşmaktadır. Deneklere 24 saat arayla üç farklı ısınma protokolü uygulanmıştır. Bunlar, (1) germe egzersizleri protokolü (GEP), (2) pliometrik egzersizler protokolü (PEP) ve (3) süspansiyon egzersizler protokolünden (SEP) oluşmaktadır. Denekler her ısınma protokolünden önce 5 dakika genel ısınma yapmış ve hemen sonrasında ön testler yapılmıştır. Isınma protokolünün uygulanmasından hemen sonra da son test yapılmıştır. Deneklere ön ve son test olarak statik denge, dikey sıçrama, 30 metre sürat, reaksiyon ve esneklik testleri uygulanmıştır. Verilerin analizi için SPSS 22.0 for Windows programı kullanılmıştır. Elde edilen verilerin karşılaştırılması Paired-Samples T testi ile yapılmıştır. Anlamlılık düzeyi p<0.05 olarak kabul edilmiştir. Bulgular: Ön test ve son test verilerinin analizi sonucunda, statik denge testinde üç protokolde de anlamlı bir fark tespit edilmemiştir (p<0.05). Dikey sıçrama testi incelendiğinde, GEP'te istatistiksel olarak anlamlı bir gerileme tespit edilirken, PEP ve SEP'te bir fark tespit edilmemiştir (p<0.05). Reaksiyon değerleri incelendiğinde üç protokolde de anlamlı bir fark tespit edilmemiştir (p<0.05). Sürat değerleri incelendiğinde, GEP'te istatistiksel olarak anlamlı gerileme, PEP ve SEP'te anlamlı gelişme tespit edilmiştir (p<0.05). Esneklik değerleri incelendiğinde üç protokolde de istatistiksel olarak anlamlı bir gelişme olduğu tespit edilmiştir (p<0.05). Sonuç: GEP'te anaerobik güç ve sürat testlerinde istatistiksel olarak anlamlı gerileme, esneklikte anlamlı gelişme görülmüştür. PEP ve SEP'te sürat ve esneklik değerlerinde anlamlı gelişme görülmüştür. Çıkan sonuçlara göre sıçrama ve sürat gerektiren sporlarda pliometrik ve süspansiyon egzersizlerle yapılan ısınmaların, esneklik gerektiren sporlarda da germe egzersizlerinin de dâhil edildiği ısınmaların daha faydalı olacağı düşünülmektedir.The aim of present study was to investigate the acute effects of different warm-up protocols on elite athlete's performance. Materials and Methods: Subject group of the study was consisted of twenty volunteer male students from Uludag University Sport Sciences Faculty who have been playing soccer at various leagues for at least seven years and those who have had no injury for last six months. Three different warm-up methods were applied to the subjects at 24 hours intervals. These were (1) stretching exercises protocol (SEP), plyometric exercises protocol (PEP) and suspension exercises protocol (SUEP). Subjects performed general warm up during 5 minutes and after then pre-tests were measured before each warm up protocol. After each warm up protocol, post-tests were measured. All subjects were tested on static balance, vertical jump, 30 m. sprint, reaction time and flexibility performances. All data were analyzed using Paired Sample T-tests using SPSS Statistics v.22 (Chicago, IL, USA), and significance was set at an alpha level of 0.05. Results: As a result of analysis of test data, no significant difference was detected in the static balance test in the three protocols (p<0.05). When the vertical jump test (anaerobic power test) results were analyzed, whilst a statistically significant decrease was detected in SEP, no difference was detected in PEP and SUEP (p<0.05). When the reaction time test results were analyzed, no difference was detected in the three protocols (p<0.05). When the speed test results were analyzed, a statistically significant decrease in SEP and statistically significant increase in PEP and SUAP were detected (p<0.05). When the flexibility test results were analyzed, a statistically significant increase was detected in the three protocols (p<0.05). Conclusion: A statistically significant decrease in the values of anaerobic power and speed, significant improvement in flexibility was observed in GEP. A significant improvement was observed in the values of speed and flexibility in PEP and SEP. According to the results, in sports that require speed and jumping, whilst plyometric and suspension warm up exercises are thought to be beneficial, in sports that require flexibility, the inclusion of static stretching to these exercises is thought to be beneficial

Donör nefrektomi uygulanan olgularda hipertansiyon gelişimi ve risk faktörlerini belirlemek

Bu tezin, veri tabanı üzerinden yayınlanma izni bulunmamaktadır. Yayınlanma izni olmayan tezlerin basılı kopyalarına Üniversite kütüphaneniz aracılığıyla (TÜBESS üzerinden) erişebilirsiniz.[Abstarct Not Available

İnvestigation the flame retardancy properties of Cotton fabric treated with nanosols containing Huntite-hydromagnesite

Bu tez çalışması Pamukkale Üniversitesi Bilimsel Araştırma Projeleri Koordinasyon birimi tarafından 2018FEBE070 tarafından nolu proje ile desteklenmiştir.Yaşamın her alanında kullandığımız araç gereçlerin yangın riskine karşı iyi korunması gerekmektedir. “Yanabilirlik” bu ürünlerin en önemli dezavantajı konumundadır. Güç tutuşurluk maddelerinin eklenmesi ile herhangi bir yangın kazası durumunda zararlar ve kayıplar engellenebilmektedir. Bu nedenle yaşamsal alanda kullanılan ürünlere eklenen güç tutuşurluk maddeleri giderek önem kazanmaktadır. Huntit-hidromanyezit mineral karışımı; güç tutuşurluk malzemesi, boya, plastik, polimer, özel lastik ve ilaç sanayisinde kullanılmaktadır. Huntithidromanyezit karışım mineralinin en önemli özelliği güç tutuşurluk etkinliği olmasıdır. Literatürde huntit-hidromanyezit karışımlarının polimer kompozitlere güç tutuşurluk dolgu maddesi olarak ilave edildiği çalışmalar bulunmasına rağmen tekstil malzemelerine sol-jel yöntemi kullanılarak aktarıldığı az sayıda çalışma bulunmaktadır.Bu tez çalışmasında, pamuklu kumaşlara güç tutuşurluk özelliği kazandırmak için sol-jel yöntemi ile güç tutuşurluk özelliğine sahip huntithidromanyezit minerali ilave edilerek nanosoller hazırlanıp pamuklu kumaşlara aktarılmıştır. Bu amaç için öncelikle huntit-hidromanyezit tozlarının silanlar ve yükseltgen maddeler kullanılarak yüzey modifikasyonu yapılmıştır. Ardından yüzey modifikasyonu gerçekleştirilmiş huntit-hidromanyezit katkılı ve silan esaslı nanosoller hazırlanarak pamuklu kumaşlara emdirme-kurutma-fiksaj yöntemi ile kaplama yapılmıştır. Kaplanmış kumaşların morfolojik yapısını belirlemek için FTIR-ATR ve SEM-EDS cihazları kullanılarak analizler yapılmıştır. Güç tutuşurluk özelliklerini belirlemek için kaplanmış kumaşların LOI testi, DTA-TG analizleri, koni kalorimetre analizi, dikey güç tutuşurluk testi, kül içeriği tespiti ve piroliz gaz kromatografisi-kütle spektroskopisi analizi gerçekleştirilmiştir. Ayrıca kaplanmış kumaşların kütlesel artış, beyazlık ve sarılık ve mukavemet değerlerini belirlemek için analizler yapılmıştır.In all fields of life the tools and equipment we used must be well protected against fire risk. “Flammability” is the major disadvantage of these products. The addition of flame retardants to the products can prevent damages and losses in case of a fire accident. Therefore, adding flame retardants to products are becoming increasingly important to use of them. Huntite-hydromagnesite mixture is used in flame retardant, dying, plastic, polymer, special rubber and pharmaceutical industries. Flame retardancy is the most important property of huntitehydromagnesite mixture. In literature, there are studies where huntitehydromagnesite mixtures were added to polymer composites as flame retardant fillers. However, there is limited reported study in which huntite-hydromagnesite mixture are transferred to textile materials by sol-gel method. In this thesis, nanosols consisting of huntite-hydromagnesite mineral and silanes were prepared by sol-gel method and transferred to cotton fabric to achive flame retardant coated cotton fabrics. For this purpose, the surface modification of huntite-hydromagnesite powders has been carried out using silanes and oxidizing agents. After that, surface modified huntite-hydromagnesite powders and silane based nanosols were prepared and coated to cotton fabrics by pad-dry-cure method. Morphological structures of coated facbric were determined by FTIR-ATR and SEM-EDS instruments. LOI test, DTA-TG analysis, cone calorimeter analysis, vertical flame retardancy test, ash content analysis and pyrolysis gas chromatography-mass spectroscopy analysis were carried out to determine flame retardancy properties of coated fabrics. In addition, tensile strength, add-on, whiteness and yellowness index values of coated fabrics were measured