Metz – 8 rue des Robert

Identifiant de l'opération archéologique : F1357200100082A Date de l'opération : 2001 (EV) Située à l'angle de la rue des Robert et de la rue Kellermann, cette parcelle d'une surface de 570 m2 a fait l'objet d'une opération de diagnostic. Le terrain, perturbé par plusieurs excavations modernes, n'a livré aucun indice archéologique

Verdun – Hôpital Saint-Nicolas, pôle mère-enfant

Identifiant de l'opération archéologique : F1355200100037 Date de l'opération : 2001 (EV) Le projet de réalisation d'un pôle « Mère-Enfant », au sein de l'hôpital Saint-Nicolas, a motivé une campagne de sondages de diagnostic, portant sur une emprise de l'ordre de 4 000 m2. Situé extra muros, au sud de l'espace urbanisé ancien, le quartier Saint-Nicolas est occupé dès le XIIIe s., comme en témoigne la donation vers 1220 par l'évêque Jean d'Apremont d'un prieuré préexistant, qui devient, en 1..

Verdun

Identifiant de l'opération archéologique : F1355200100037 Date de l'opération : 2001 (EV) Le projet de réalisation d'un pôle « Mère-Enfant », au sein de l'hôpital Saint-Nicolas, a motivé une campagne de sondages de diagnostic, portant sur une emprise de l'ordre de 4 000 m2. Situé extra muros, au sud de l'espace urbanisé ancien, le quartier Saint-Nicolas est occupé dès le XIIIe s., comme en témoigne la donation vers 1220 par l'évêque Jean d'Apremont d'un prieuré préexistant, qui devient, en 1..

Functional Diversification of Fungal Glutathione Transferases from the Ure2p Class

The glutathione-S-transferase (GST) proteins represent an extended family involved in detoxification processes. They are divided into various classes with high diversity in various organisms. The Ure2p class is especially expanded in saprophytic fungi compared to other fungi. This class is subdivided into two subclasses named Ure2pA and Ure2pB, which have rapidly diversified among fungal phyla. We have focused our analysis on Basidiomycetes and used Phanerochaete chrysosporium as a model to correlate the sequence diversity with the functional diversity of these glutathione transferases. The results show that among the nine isoforms found in P. chrysosporium, two belonging to Ure2pA subclass are exclusively expressed at the transcriptional level in presence of polycyclic aromatic compounds. Moreover, we have highlighted differential catalytic activities and substrate specificities between Ure2pA and Ure2pB isoforms. This diversity of sequence and function suggests that fungal Ure2p sequences have evolved rapidly in response to environmental constraints

Comparison of mosquito and fly derived DNA as a tool for sampling vertebrate biodiversity in suburban forests in Berlin, Germany

The use of invertebrate‐derived DNA (iDNA) is a promising non‐invasive tool to monitor wildlife. While most studies have been carried out in dense tropical and sub‐tropical forests and have focused on the use of a single category of invertebrates, this study compares the use of flies and mosquitoes‐derived DNA to assess vertebrate diversity in semi‐urban environments. We conducted our sampling in four different forest plots in Berlin, Germany. Pools of flies and non‐bloodfed mosquitoes were metabarcoded using 108‐bp vertebrate‐specific 12 S rRNA (12 S‐V5) and 94‐bp mammal‐specific 16 S rRNA (16Smam) mitochondrial markers, and individual bloodfed mosquitoes were sequenced using the 340‐bp vertebrate‐specific 12 S rRNA fragment (Mam‐12 S‐340). Most sequencing was only successful for mammal species. From the fly pools, we detected 10 mammal species using 16Smam, and six species using 12 S‐V5. From the non‐bloodfed mosquito pools, we only amplified putative contaminant DNA, indicating that mosquito females without visual signs of a blood meal carry no traces of vertebrate DNA. Finally, in the bloodfed mosquitoes, we identified four mammal species. We did not find significant differences in the proportion of mammal species detected regarding the total available number of species between sampling localities. Fly samples were easier to obtain and more abundant over the sampled localities compared to mosquito samples. We conclude that, while there are a few advantages in using mosquito blood meals, the use of flies in the detection of wildlife in a suburban environment is more effective in terms of collection of samples and detection of vertebrates, although this technique is limited to few mammal species in the urban environment

Microglia maintain structural integrity during fetal brain morphogenesis

Microglia (MG), the brain-resident macrophages, play major roles in health and disease via a diversity of cellular states. While embryonic MG display a large heterogeneity of cellular distribution and transcriptomic states, their functions remain poorly characterized. Here, we uncovered a role for MG in the maintenance of structural integrity at two fetal cortical boundaries. At these boundaries between structures that grow in distinct directions, embryonic MG accumulate, display a state resembling post-natal axon-tract-associated microglia (ATM) and prevent the progression of microcavities into large cavitary lesions, in part via a mechanism involving the ATM-factor Spp1. MG and Spp1 furthermore contribute to the rapid repair of lesions, collectively highlighting protective functions that preserve the fetal brain from physiological morphogenetic stress and injury. Our study thus highlights key major roles for embryonic MG and Spp1 in maintaining structural integrity during morphogenesis, with major implications for our understanding of MG functions and brain development.</p

Metz (Moselle). Lycée Fabert

Thion Pierre. Metz (Moselle). Lycée Fabert. In: Archéologie médiévale, tome 25, 1995. p. 334

Florange (Moselle). Rue du Bourg.

Thion Pierre. Florange (Moselle). Rue du Bourg. . In: Archéologie médiévale, tome 21, 1991. p. 354

Vic-sur-Seille (Moselle). 10, rue de la Gare.

Thion Pierre. Vic-sur-Seille (Moselle). 10, rue de la Gare. . In: Archéologie médiévale, tome 21, 1991. pp. 377-378