Undesigning sound: AdriftPM’s Portable Soundscapes

This is the author accepted manuscript. The final version is available from the publisher via the DOI in this record.In July 2015, Adrift Performance Makers developed the project Portable Soundscapes: An Acoustic Travelogue, travelling down from Portsmouth, UK, to Thessaloniki, Greece, through Paris, Munich, Zagreb, and Belgrade. Carrying pre-recorded Southsea sound clips in their luggage, they listened out for unexpected voicings, misplaced soundtracks, fleeting sonic passersby. The project was curated as a series of online responses to inadvertent encounters with unfamiliar sonic environments. AdriftPM developed DIY strategies of aural dramaturgy, such as sonic conflations, sonic invitations, impromptu compositions, short poetic responses, and dubious definitions of sound terminology. This project revealed sound design as the enabling condition of a theatre, as the very organizing principle of a performative dramaturgy of listening, therefore effecting a reversal of conventional understandings of theatre sound design, which presuppose theatre as the context and sound as the designed intervention. This article seeks to lend an attentive ear to such unspoken assumptions. What if the complexity of the project posits the listener as both the deviser of the audio project and the spectator of the ongoing process that is the project? What happens when both audience and performance are diffused across a variety of media? What practices of listening, designing and archiving are required when Europe is your stage

Mapping heterogeneous research infrastructure metadata into a unified catalogue for use in a generic virtual research environment

Virtual Research Environments (VREs), also known as science gateways or virtual laboratories, assist researchers in data science by integrating tools for data discovery, data retrieval, workflow management and researcher collaboration, often coupled with a specific computing infrastructure. Recently, the push for better open data science has led to the creation of a variety of dedicated research infrastructures (RIs) that gather data and provide services to different research communities, all of which can be used independently of any specific VRE. There is therefore a need for generic VREs that can be coupled with the resources of many different RIs simultaneously, easily customised to the needs of specific communities. The resource metadata produced by these RIs rarely all adhere to any one standard or vocabulary however, making it difficult to search and discover resources independently of their providers without some translation into a common framework. Cross-RI search can be expedited by using mapping services that harvest RI-published metadata to build unified resource catalogues, but the development and operation of such services pose a number of challenges. In this paper, we discuss some of these challenges and look specifically at the VRE4EIC Metadata Portal, which uses X3ML mappings to build a single catalogue for describing data products and other resources provided by multiple RIs. The Metadata Portal was built in accordance to the e-VRE Reference Architecture, a microservice-based architecture for generic modular VREs, and uses the CERIF standard to structure its catalogued metadata. We consider the extent to which it addresses the challenges of cross-RI search, particularly in the environmental and earth science domain, and how it can be further augmented, for example to take advantage of linked vocabularies to provide more intelligent semantic search across multiple domains of discourse

COVID-19 Pandemic: Prevention and protection measures to be adopted at the workplace

SARS-CoV-2, identified in Wuhan, China, for the first time in December 2019, is a new viral strain, which has not been previously identified in humans; it can be transmitted both by air and via direct and indirect contact; however, the most frequent way it spreads is via droplets. Like the other viruses belonging to the same family of coronaviruses, it can cause from mild flu-like symptoms, such as cold, sore throat, cough and fever, to more severe ones such as pneumonia and breathing difficulties, and it can even lead to death. Since no effective specific drug therapy has been found yet, nor any vaccine capable of limiting the spread of this pathogen, it is important for ways of preventing the spread of this infection to be established. The purpose of our research was to provide a protocol to prevent the spread of SARS-CoV-2 infection in light of the limited information related to this coronavirus. In detail, we analysed and searched targeted evidence-based guidelines issued in the various countries affected by this epidemic up till now. In addition, we analyzed the recommendations for the prevention and control of other epidemics caused by other pathogens belonging to the same family of coronaviruses or others that present the same mechanisms of transmission. General organizational measures regarding the containment and management of the epidemiological emergency of COVID-19 have been imposed by the competent authorities for an adequate and proportionate management of the evolution of the epidemiological situation. The prevention and protection organizational measures therefore aim to minimize the probability of being exposed to SARS-CoV-2. For this purpose, measures must also be taken at work to avoid new infections or even the spread of the virus where it has already been present. Furthermore, environmental measures are aimed at reducing the risk of transmission of SARS-CoV-2 to individuals through contact with infected subjects, objects, equipment, or contaminated environmental surfaces. Protective devices must be used whenever there is potentially close contact with a suspect case, especially when the potentially infected person does not wear a surgical mask that could reduce the spread of viruses in the environment. By adopting this specific prevention and protection measures recommended in the workplace, it will be possible to help overcome this COVID-19 pandemic

Building an Integrated Enhanced Virtual Research Environment Metadata Catalogue

Purpose The purpose of this paper is to boost multidisciplinary research by the building of an integrated catalogue or research assets metadata. Such an integrated catalogue should enable researchers to solve problems or analyse phenomena that require a view across several scientific domains. Design/methodology/approach There are two main approaches for integrating metadata catalogues provided by different e-science research infrastructures (e-RIs): centralised and distributed. The authors decided to implement a central metadata catalogue that describes, provides access to and records actions on the assets of a number of e-RIs participating in the system. The authors chose the CERIF data model for description of assets available via the integrated catalogue. Analysis of popular metadata formats used in e-RIs has been conducted, and mappings between popular formats and the CERIF data model have been defined using an XML-based tool for description and automatic execution of mappings. Findings An integrated catalogue of research assets metadata has been created. Metadata from e-RIs supporting Dublin Core, ISO 19139, DCAT-AP, EPOS-DCAT-AP, OIL-E and CKAN formats can be integrated into the catalogue. Metadata are stored in CERIF RDF in the integrated catalogue. A web portal for searching this catalogue has been implemented. Research limitations/implications Only five formats are supported at this moment. However, description of mappings between other source formats and the target CERIF format can be defined in the future using the 3M tool, an XML-based tool for describing X3ML mappings that can then be automatically executed on XML metadata records. The approach and best practices described in this paper can thus be applied in future mappings between other metadata formats. Practical implications The integrated catalogue is a part of the eVRE prototype, which is a result of the VRE4EIC H2020 project. Social implications The integrated catalogue should boost the performance of multi-disciplinary research; thus it has the potential to enhance the practice of data science and so contribute to an increasingly knowledge-based society. Originality/value A novel approach for creation of the integrated catalogue has been defined and implemented. The approach includes definition of mappings between various formats. Defined mappings are effective and shareable.Published929-9514IT. Banche datiJCR Journa

Effect of dietary seaweed (Ascophyllum nodosum) supplementation on milk mineral concentrations, transfer efficiency, and hematological parameters in lactating Holstein cows

This study investigated the effect of feeding seaweed (Ascophyllum nodosum) to dairy cows on milk mineral concentrations, feed-to-milk mineral transfer efficiencies and hematological parameters. Lactating Holstein cows (n = 46) were allocated to one of 2 diets (n = 23 each): (i) control (CON; without seaweed), and (ii) seaweed (SWD; replacing 330 g/d of dried corn meal in CON with 330 g/d dried A. nodosum). All cows were fed the CON diet for 4 weeks before the experiment (adaptation period); and animals were then fed the experimental diets for 9 weeks. Samples included sequential 3-week composite feed samples, a composite milk sample on the last day of each week, and a blood sample at the end of the study. Data were statistically analyzed using a linear mixed effects model with diet, week, and their interaction as fixed factors; cow (nested within diet) as a random factor and data collected on the last day of the adaptation period as covariates. Feeding SWD increased milk concentrations of Mg (+6.6 mg/kg), P (+56 mg/kg), and I (+1720 μg/kg). It also reduced transfer efficiency of Ca, Mg, P, K, Mn, and Zn, and increased transfer efficiency of Mo. Feeding SWD marginally reduced milk protein concentrations while there was no effect of SWD feeding on cows' hematological parameters. Feeding A. nodosum increased milk I concentrations, which can be beneficial when feed I concentration is limited or in demographics or populations with increased risk of I deficiency (e.g., female adolescents, pregnant women, nursing mothers). However, care should also be taken when feeding SWD to dairy cows because, in the present study, milk I concentrations were particularly high and could result in I intakes that pose a health risk for children consuming milk.The project leading to these results has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement no. 730924 (SmartCow). The analysis of macrominerals and trace elements in feed, milk, and blood plasma was funded by the University of Reading (Reading, UK); special thanks go to the laboratory personnel at the University of Reading who supported the analysis of feed, milk, and blood plasma. This output reflects only the authors' views, and the European Union cannot be held responsible for any use that may be made of the information contained therein. The data set supporting the conclusions of this article is available on request from the corresponding authors. Eric E. Newton: conceptualization, methodology, software, validation, formal analysis, investigation, data curation, writing–original draft, writing–review and editing, visualization. Katerina Theodoridou: conceptualization, methodology, resources, writing–review and editing, supervision, project administration, funding acquisition. Marta Terré: project administration, investigation, resources, writing–review and editing. Sharon Huws: writing–review and editing. Partha Ray: conceptualization, methodology, software, supervision. Christopher K. Reynolds: writing–review and editing, supervision. N. Prat: investigation, resources. D. Sabrià: investigation, resources. Sokratis Stergiadis: conceptualization, methodology, resources, data curation, writing–original draft, writing–review and editing, visualization, supervision, project administration. All authors reviewed and approved the manuscript. Animals were managed with common rearing conditions under the supervision of Institute of Agrifood Research and Technology (IRTA, Monells, Spain) technicians and the approval of the Animal Care Committee of the Government of Catalonia (authorization code 11392). The authors have not stated any conflicts of interest.info:eu-repo/semantics/publishedVersio

Prognostic factors related to sequelae in childhood bacterial meningitis: Data from a Greek meningitis registry

<p>Abstract</p> <p>Background</p> <p>Bacterial meningitis (BM) is a life-threatening disease, often related with serious complications and sequelae. Infants and children who survive bacterial meningitis often suffer neurological and other sequelae.</p> <p>Methods</p> <p>A total of 2,477 patients aged 1 month to 14 years old hospitalized in a Children's Hospital in Greece diagnosed with acute bacterial meningitis were collected through a Meningitis Registry, from 1974 to 2005. Clinical, laboratory and other parameters (sex, age, pathogen, duration of symptoms before and after admission) were evaluated through univariate and multivariate analysis with regard to sequelae. Analysis of acute complications were also studied but not included in the final model.</p> <p>Results</p> <p>The rate of acute complications (arthritis and/or subdural effusion) was estimated at 6.8% (152 out of 2,251 patients, 95%CI 5.8-7.9) while the rate of sequelae (severe hearing loss, ventriculitis, hydrocephalus or seizure disorder) among survivors was estimated at 3.3% (73 out of 2,207 patients, 95%CI 2.6-4.2). Risk factors on admission associated with sequelae included seizures, absence of hemorrhagic rash, low CSF glucose, high CSF protein and the etiology of meningitis. A combination of significant prognostic factors including presence of seizures, low CSF glucose, high CSF protein, positive blood culture and absence of petechiae on admission presented an absolute risk of sequelae of 41.7% (95%CI 15.2-72.3).</p> <p>Conclusions</p> <p>A combination of prognostic factors of sequelae in childhood BM may be of value in selecting patients for more intensive therapy and in identifying possible candidates for new treatment strategies.</p

Evaluation of Correlation between Sleep and Psychiatric Disorders in a Population of Night Shift Workers: A Pilot Study

Background: Insomnia is the perception of inadequate, insufficient or non-restorative sleep. Of all sleep-related disorders, insomnia is the most common. It is important to remember that the sleep-wake cycle also plays a central role in the genesis of anxiety and depression. The aim of our study is to evaluate the association between sleep disturbances and anxiety and depression in a group of workers of both sexes who perform night shift work. Methods: Information on sleep disorders was collected by administering the Insomnia Severity Index (ISI) questionnaire. Statistical analysis was conducted using the Chi-square test to assess whether there were any differences between sex for those who were healthy or who were diagnosed with psychiatric disorders. Results: The results showed that there was a good percentage of subjects with insomnia problems, impairing normal daily activities and promoting the onset of fatigue, daytime sleepiness, cognitive performance deficits and mood disorders. Conclusion: We highlighted how anxious and depressive anxiety disorders are more pronounced in people who suffer from altered sleep-wake rhythms. Further research in this direction could prove to be fundamental for understanding the genesis of the onset of other disorders as well

Neurocognitive profiles in help-seeking individuals: comparison of risk for psychosis and bipolar disorder criteria

Background. Neurocognitive deficits are important aspects of the schizophrenic disorders because they have a strong impact on social and vocational outcomes. We expanded on previous research by focusing on the neurocognitive profiles of persons at high risk (HR) or ultra-high risk (UHR) for schizophrenic and affective psychoses. Our main aim was to determine whether neurocognitive measures are sufficiently sensitive to predict a group affiliation based on deficits in functional domains. Method. This study included 207 help-seeking individuals identified as HR (n=75), UHR (n=102) or at high risk for bipolar disorder (HRBip; n=30), who were compared with persons comprising a matched, healthy control group (CG; n=50). Neuropsychological variables were sorted according to their load in a factor analysis and were compared among groups. In addition, the likelihood of group membership was estimated using logistic regression analyses. Results. The performance of HR and HRBip participants was comparable, and intermediate between the controls and UHR. The domain of processing speed was most sensitive in discriminating HR and UHR [odds ratio (OR) 0.48, 95% confidence interval (CI) 0.28-0.78, p=0.004] whereas learning and memory deficits predicted a conversion to schizophrenic psychosis (OR 0.47, 95% CI 0.25-0.87, p=0.01). Conclusions. Performances on neurocognitive tests differed among our three at-risk groups and may therefore be useful in predicting psychosis. Overall, cognition had a profound effect on the extent of general functioning and satisfaction with life for subjects at risk of psychosis. Thus, this factor should become a treatment target in itsel

Performance and milk quality parameters of Jersey crossbreds in low-input dairy systems

Previous work has demonstrated some benefit from alternative breeds in low-input dairying, although there has been no systematic analysis of the simultaneous effect of Jersey crossbreeding on productivity, health, fertility parameters or milk nutritional quality. This work aimed to understand the effects of, and interactions/interrelations between, dairy cow genotypes (Holstein-Friesian (HF), Holstein-Friesian × Jersey crossbreds (HF × J)) and season (spring, summer, autumn) on milk yield; basic composition; feed efficiency, health, and fertility parameters; and milk fatty acid (FA) profiles. Milk samples (n=219) and breed/diet data were collected from 74 cows in four UK low-input dairy farms between March and October 2012. HF × J cows produced milk with more fat (+3.2 g/kg milk), protein (+2.9 g/kg milk) and casein (+2.7 g/kg milk); and showed higher feed, fat, and protein efficiency (expressed as milk, fat and protein outputs per kg DMI) than HF cows. Milk from HF × J cows contained more C4:0 (+2.6 g/kg FA), C6:0 (+1.9 g/kg FA), C8:0 (+1.3 g/kg FA), C10:0 (+3.0 g/kg FA), C12:0 (+3.7 g/kg FA), C14:0 (+4.6 g/kg FA) and saturated FA (SFA; +27.3 g/kg milk) and less monounsaturated FA (MUFA; -23.7 g/kg milk) and polyunsaturated FA (-22.3 g/kg milk). There was no significant difference for most health and fertility parameters, but HF × J cows had shorter calving interval (by 39 days). The superior feed, fat and protein efficiency of HF × J cows, as well as shorter calving interval can be considered beneficial for the financial sustainability of low-input dairy farms; and using such alternative breeds in crossbreeding schemes may be recommended. Although statistically significant, it is difficult to determine if differences observed between HF and HF × J cows in fat composition are likely to impact human health, considering average population dairy fat intakes and the relatively small difference. Thus, the HF × J cow could be used in low-input dairying to improve efficiency and productivity without impacting milk nutritional properties

Navigating paediatric virology through the COVID‑19 era (Review).

The present review article presents the key messages of the 8th Workshop on Paediatric Virology organised virtually by the Institute of Paediatric Virology based on the island of Euboea in Greece. The major topics covered during the workshop were the following: i) New advances in antiviral agents and vaccines against cytomegalovirus; ii) hantavirus nephropathy in children; iii) human rhinovirus infections in children requiring paediatric intensive care; iv) complications and management of human adenovirus infections; v) challenges of post‑coronavirus disease 2019 (COVID‑19) syndrome in children and adolescents; and vi) foetal magnetic resonance imaging in viral infections involving the central nervous system. The COVID‑19 era requires a more intensive, strategic, global scientific effort in the clinic and in the laboratory, focusing on the diagnosis, management and prevention of viral infections in neonates and children