6 research outputs found
An Empirical Approach to Understanding the Relationship Between Recombination and Fitness
The persistence of sex is a recurrent conundrum in evolutionary biology because
sex is costly. These costs may be accounted for by looking at the outcome of sex, namely
that sex causes genetic mixing. Recombination is one of the processes by which sex causes genetic mixing; determining when recombination is advantageous may alleviate some of the costs of sex. The advantages of recombination are in the effects of recombination and the influences thereupon. The first experiment focuses on the effects of recombination on the mean fitness and variance in fitness. A second experiment examines the influences on
recombination by addressing whether recombination is a general response to poor
condition. Specifically, the impact on recombination rate of genotypes with variable fitness is investigated. Differing fitness effects are not correlated to recombination rates. Conversely, coincidence, a recombination related trait, is positively correlated with fitness.MAS
Data from: The effect of deleterious mutations and age on recombination in Drosophila melanogaster
At the population level, recombination mediates the efficiency with which selection can eliminate deleterious mutations. At the individual level, deleterious alleles may influence recombination, which would change the rate at which linkage disequilibrium is eroded and thereby alter the efficiency with which deleterious alleles are purged. Here we test whether the presence of a deleterious allele on one autosome affects recombination on another autosome. We find that deleterious alleles not only alter the rate but also the pattern of recombination. However, there is little support that different deleterious alleles affect recombination in a consistent manner. Because we have detailed information on individual females across their life times, we are able to examine how recombination patterns change with age and find that these patterns are also affected by the presence of deleterious alleles. The differences among genotypes or among age classes is large enough to add substantial noise to genetic mapping experiments that do not consider these sources of variation
C2DataByAgeForArchiving
"C2" data, offspring produced by ag
C3DataByAgeForArchiving
"C3" data, offspring produced by ag
C3TotalsDataForArchiving
"C3" data, lifetime total offspring productio
C2TotalsDataForArchiving
"C2" data, lifetime offspring productio