Instagram travel influencers coping with covid-19 travel disruption

A significant portion of today’s marketing is done through social media influencers, that is, through bloggers with established online credibility in a certain area who are recognized and followed by a sizable online audience. In the travel and hospitality industry, the influencer marketing is primarily done through Instagram due to its emphasis on visual images rather than texts. Covid-19 related travel restrictions and shrinking social media advertisement in travel industry have heavily impacted travel influencers, reducing their income and forcing many out of business. We present the outcomes of a study of the top 150 online travel influencers. The analysis is based on 11,000 photographs and texts published in two time periods before and during COVID-19 epidemics. We found that COVID-19 has induced transformative changes in the influencers’ online behavior reflected in changes in their posting frequency, themes, and expressed emotions

Enhanced bone apposition to Brazilian microrough titanium surfaces

It has recently been reported that machined and microrough (micro) Brazilian titanium (Ti) implants have good production standards. The aim of this study was to evaluate in vivo bone formation around 2 different implant surfaces placed in dog's mandible. Thirty-two screw-typed Ti implants were used in this study. Mandibular premolars were extracted in 8 dogs and, after 12 weeks, 2 machined (Neodent Titamax, Brazil) and 2 micro implants (Neodent Titamax Porous, Brazil) were placed in each animal. Biopsies were taken at 3 and 8 weeks post-implantation and stained with Stevenel's blue and Alizarin red for histomorphometric measurements of bone-to-implant contact (BIC), bone area between threads (BABT) and bone area within the mirror area (BAMA). Data were analyzed statistically by two-way ANOVA (&#945;=0.05). While at 3 weeks micro implants exhibited significantly more BIC than machined ones (55 &plusmn; 12.5% and 35.6 &plusmn; 15%, p<0.05), no significant difference in such parameter was detected at 8 weeks (51.2 &plusmn; 21% and 48.6 &plusmn; 18.1%, p>0.05). There were no significant differences in BABT and BAMA between the implants. Micro surfaces promoted higher contact osteogenesis. These data indicate that this commercial micro Ti implant surface enhances contact osteogenesis at an early post-implantation period when compared to the machined one.Estudos recentes demonstram que implantes nacionais de titânio (Ti) usinados e micro-rugosos apresentam padrões adequados de produção. O objetivo deste estudo foi de avaliar a neo-formação óssea in vivo em 2 tipos diferentes de implantes colocados em mandíbulas de cães. Trinta e dois implantes rosqueáveis de Ti foram utilizados neste estudo. Os pré-molares mandibulares de 8 cães foram extraídos e, após 12 semanas, 2 implantes usinados (Neodent Titamax) e 2 implantes micro-rugosos (Neodent Titamax Porous) foram colocados em cada animal. Após 3 e 8 semanas da implantação os espécimes foram biopsiados, corados com Stevenel's blue e Alizarin red e analisados histomorfometricamente quanto à porcentagem de contato-osso-implante (COI), área de osso mineralizado entre as roscas (OMER) e área de osso mineralizado na área em espelho (OMAE). Os resultados foram analisados estatisticamente pelo teste de ANOVA a dois fatores. Os implantes micro-rugosos apresentaram maior COI do que os implantes controle em 3 semanas (55,0 &plusmn; 12,5% e 35,6 &plusmn; 15,0%; p<0,05), enquanto não houve diferença em 8 semanas (51,2 &plusmn; 21,0% e 48,6 &plusmn; 18,1%; p>0,05). Não houve diferença quanto ao OMER e OMAE. Esses dados nos indicaram que os implantes micro-rugosos utilizados neste estudo aumentam a osteogênese de contato nos períodos iniciais pós-implantação quando comparados com implantes usinados.(FAPESP) São Paulo Research Foundation(CNPq) The National Council for Scientific and Technological Developmen

Prevalence of suicide risk and comorbidities in postpartum women in Pelotas

AbstractObjectivesTo evaluate the prevalence of suicide risk and comorbidities in postpartum women.MethodsThis is a cross-sectional study of postpartum women. The sample comprised mothers who have received prenatal care from the Brazilian National System of Public Heath in the city of Pelotas. Suicide risk and other mental disorders were evaluated using the Mini International Neuropsychiatric Interview (MINI). A yes answer on one of the six interview questions was considered a sign of suicide risk.ResultsThe sample consisted of 919 postpartum women. The 11.5% suicide prevalence was 4.62 (CI 2.45, 8.73) times higher in women with low educational levels. Women with comorbid depression or an anxiety disorder showed a 17.04 (CI 2.27; 19.96) times greater risk of suicide than those who did not suffer from any mood disorder.ConclusionLower education levels and psychiatric disorders are associated with suicide risk. Bipolar disorder is the psychiatric disorder with the highest impact on suicide risk

Aplicação de Ferramentas CAE/CAD e Inventor como demonstração de forças nos planos horizontal e inclinado para a primeira série do ensino médio

O conceito abordado para elaboração do projeto é o estudo dinâmico de forças com destaque no projeto para análise em um plano horizontal e inclinado conteúdo esse de difícil visualização por parte da maioria dos discentes em relação ao fenômeno ocorrido. Ferramentas CAE/CAD (do Inglês, Engenharia Auxiliada por computador e Desenho assistido por Computador) despertarão a curiosidade dos alunos, integrando-os à tecnologia e dando sentido ao que estudam em sala de aula, já que apresentam uma demonstração prática de como o conteúdo de aplicação de forças poderá ser útil para a vida de todos os discentes, não só os que pretendem ter uma carreira focada na área de exatas ou particularmente na área de Engenharia

Análisis de expedientes dentales endodónticos de pacientes tratados en una universidad pública del sur de Brasil

Dental record has a fundamental role in dentist performance. This study evaluated the standard registration of dental records of patients submitted to endodontic treatment for undergraduate students (CG) and specialists endodontics students (CE) in a public university in the south of Brazil. The sample was obtained by convenience, consecutively and included dental records patients of a public university in the south of Brazil who were treated at CE and clinical records of patients who were treated at CG, during on the year 2014. Was analyzed the description of endodontic treatment, data retrieved was scored and rated using a modification of the scoring system proposed by Streiner & Norman (1996) and quality of radiographs was performed according to the guidelines of “National Radiological Protection Board”. At dental records were analyzed, 223 belong to CG and 219 belong CE. The records from CE and CG had similar information on the evaluated parameters, except for “presence of rubber dam” and “presence of abbreviature in the description” (Mann-Whitney Test, P = 0.386). The absence of periapical radiographs was higher in CE than CG records (CE = 36.77%; CG = 0.46%). (Mann-Whitney test, P<0.0001). There was a predominance of periapical radiographs with the grades “excellent” and “diagnostically acceptable” in both groups.The quality of records generally obtained good results. The incorporation of new science into the educational program like electronic records and digital imaging techniques, facilitating the constant updating of data related to health and treatment of patients improving the record of the evolution of procedures.O prontuário odontológico tem papel fundamental na atuação do cirurgião-dentista. Este estudo avaliou o padrão de registro de prontuários odontológicos de pacientes submetidos ao tratamento endodôntico por alunos de graduação (GC) e alunos especialistas em endodontia (CE) em uma universidade pública do sul do Brasil. Amostra foi obtida por conveniência, de forma consecutiva e incluiu prontuários odontológicos de pacientes atendidos por CE e prontuários de pacientes atendidos por GC, durante o ano de 2014. Foi analisada a descrição do tratamento endodôntico, os dados recuperados foram pontuados e avaliados usando uma modificação do sistema de pontuação proposto por Streiner & Norman (1996) e a qualidade das radiografias foi analisada de acordo com as diretrizes do “National Radiological Protection Board”. Nos prontuários odontológicos foram analisados, 223 pertencentes ao GC e 219 pertencentes ao CE. Os prontuários do CE e do CG apresentaram informações semelhantes sobre os parâmetros avaliados, exceto para “presença de isolamento absoluto” e “presença de abreviaturas na descrição” (Teste de Mann-Whitney, P = 0,386). A ausência de radiografias periapicais foi maior em CE do que os registros do CG (CE = 36,77%; CG = 0,46%) (Teste de Mann-Whitney, P <0,0001). Houve predomínio de radiografias periapicais com notas “excelente” e “diagnóstico aceitável” em ambos os grupos. A qualidade dos registros obteve bons resultados. Conclui-se que a incorporação de novas ciências ao programa educacional como prontuários eletrônicos e técnicas de imagem digital, facilita a atualização constante dos dados relacionados à saúde e tratamento dos pacientes, melhorando o registro da evolução dos procedimentos.El registro dental juega un papel fundamental en el desempeño del odontólogo. Este estudio evaluó el patrón de registro de registros dentales de pacientes sometidos a tratamiento de endodoncia por estudiantes de pregrado (GC) y estudiantes especialistas en endodoncia (EC) en una universidad pública en el sur de Brasil. La muestra se obtuvo por conveniencia, de forma consecutiva, e incluyó registros dentales de pacientes tratados por CE y registros médicos de pacientes tratados por GC durante 2014. La descripción del tratamiento endodóntico, los datos recuperados fueron puntuados y evaluados utilizando una modificación del sistema de puntuación propuesto por Streiner & Norman (1996) y se analizó la calidad de las radiografías de acuerdo con las directrices de la National Radiological Protection Board. En los registros dentales se analizaron 223 pertenecientes al GC y 219 pertenecientes a la CE. Las historias clínicas de la CE y CG presentaron información similar sobre los parámetros evaluados, excepto por “presencia de aislamiento absoluto” y “presencia de abreviaturas en la descripción” (prueba de Mann-Whitney, p = 0,386). La ausencia de radiografías periapicales fue mayor en los registros de EC que en los de GC (EC = 36,77%; GC = 0,46%) (prueba de Mann-Whitney, P <0,0001). Hubo un predominio de radiografías periapicales con puntajes de “excelente” y “diagnóstico aceptable” en ambos grupos. La calidad de los registros en general tuvo buenos resultados. Se concluye que la incorporación de nuevas ciencias al programa educativo, como la historia clínica electrónica y las técnicas de imagen digital, facilita la actualización constante de los datos relacionados con la salud y el tratamiento de los pacientes, mejorando el registro de la evolución de los procedimientos

Comments on “the organization of pharmaceutical services by ‘health region’ in Brazil’s Unified Health System”

O presente estudo teve o objetivo de caracterizar os serviços farmacêuticos prestados no Sistema Único de Saúde do Brasil sob a ótica das redes de atenção à saúde em regiões de saúde contempladas no Projeto QualiSUS-Rede. O estudo teve delineamento transversal, com coleta de dados de dezembro de 2013 a julho de 2015 em todos os estabelecimentos públicos de saúde que realizavam entrega/armazenamento de medicamentos (n = 4.938) de 465 municípios e Distrito Federal em 43 regiões de saúde. Os resultados mostram a existência de pelo menos um serviço gerencial de apoio à rede de saúde além do armazenamento de medicamentos em todas as regiões (> 90%). E de forma irregular entre as Regiões, há a oferta de pelo menos um serviço assistencial nos pontos de atenção pelos profissionais farmacêuticos, ocorrendo em maior proporção na Região Sudeste (74,3%) e menor na Nordeste (43,3%). Os resultados reforçam a necessidade da efetiva estruturação da assistência farmacêutica nas RAS superando uma visão restritiva das suas atividades, que valoriza quase que exclusivamente seu componente logístico de apoio a rede em detrimento da clínica. É igualmente importante ampliar e aprimorar o acesso da população aos medicamentos assim como e qualificar o cuidado em saúde ofertado aos usuários do sistema.This study aimed to describe and characterize the pharmaceutical services provided in Brazil’s Unified Health System (SUS) from the point of view of the healthcare networks that are organized by region in the QualiSUS-Rede Project. This was a cross-sectional study, with data collected from December 2013 to July 2015, in public health establishments that carried out delivery or warehousing of medications (n = 4,938), in 465 municipalites, and the Federal District, in 43‘Health Regions’. The results show the existence of at least one management service supporting the health network, and warehousing of medications in all the regions (> 90%). It also showed the availability of at least one healthcare service, in healthcare locations, by pharmaceutical professionals is irregular between the Regions, being highest in the Southeastern Region (74.3%), and lowest in the Northeastern Region (43.3%). The results underpine the need for effective structuring of pharmaceutical assistance in the SUS networks, overcoming the current restrictive vision of its activities, which gives value almost exclusively to the logistical component of support to the network, to the detriment of the clinical component. It is also important to expand, and improve the quality of, the population’s access to medical drugs, and improve the quality of the healthcare offered to users of the system

Aging, neurocognitive impairment and adherence to antiretroviral therapy in human immunodeficiency virus-infected individuals

AbstractBackground/objectiveThere is an increasing number of older patients with human immunodeficiency virus infection due to the success of antiretroviral therapy, the improved prognosis and life expectancy of patients, and the higher number of new infections among older individuals. The main objective of the present study was to compare the characteristics of older human immunodeficiency virus patients with those of younger patients.Materials and methodsWe conducted a cross-sectional study with human immunodeficiency virus-infected patients who were treated at the Specialized Care Service (Serviço de Assistência Especializada) for human immunodeficiency virus/AIDS in the city of Pelotas, South Brazil. Sociodemographic information as well as data on human immunodeficiency virus infection and treatment were collected. All participants underwent psychiatric and neurocognitive assessments, and their adherence to antiretroviral therapy was evaluated.ResultsA total of 392 patients participated in the study, with 114 patients aged 50 years and older. The characteristics showing significant differences between older and younger human immunodeficiency virus-infected patients included race/ethnicity, comorbidities, duration and adherence to antiretroviral therapy, currently undetectable viral load, and cognitive impairment. Compared to younger patients, older patients were at higher risk of exhibiting cognitive impairment [OR 2.28 (95% CI: 1.35–3.82, p=0.002)] and of having increased adherence to antiretroviral therapy [OR 3.11 (95% CI: 1.67–5.79, p<0.001)].ConclusionsThe prevalence of neurocognitive impairment remained high in human immunodeficiency virus-infected patients despite antiretroviral therapy. In the present study, the prevalence of this type of impairment was significantly higher in patients aged ≥50 years, most likely due to aging, human immunodeficiency virus infection, and a possible synergistic effect between these factors. Despite this higher prevalence, older patients exhibited higher rates of adherence to antiretroviral therapy and of undetectable human immunodeficiency virus viral load

Zmym4 is required for early cranial gene expression and craniofacial cartilage formation

The Six1 transcription factor plays important roles in the development of cranial sensory organs, and point mutations underlie craniofacial birth defects. Because Six1’s transcriptional activity can be modulated by interacting proteins, we previously screened for candidate interactors and identified zinc-finger MYM-containing protein 4 (Zmym4) by its inclusion of a few domains with a bona fide cofactor, Sine oculis binding protein (Sobp). Although Zmym4 has been implicated in regulating early brain development and certain cancers, its role in craniofacial development has not previously been described

Prevalência e fatores associados ao sobrepeso e à obesidade em adolescentes

OBJECTIVE: To assess the prevalence and factors associated to overweight and obesity in urban area adolescents. METHODS: A cross-sectional population-based study was carried out in the municipality of Pelotas, Southern Brazil, between 2001 and 2002. Adolescents between 15 and 18 years old were weighed, measured and asked to complete a self-administered questionnaire. Of 90 areas drawn, 86 dwellings were visited in each area, comprising a total of 960 adolescents interviewed. Overweight and obesity prevalences were defined based on the body mass index, according to cutoff values and adjusted to age and sex. Multivariate analysis with Poisson regression was performed using a hierarchical model of variables associated to overweight and obesity. RESULTS: Overweight and obesity prevalences were 20.94% and 5% respectively. There was found an inverse relationship between obesity and age and schooling. An association of overweight and obesity with reporting parents' obesity (p=0.03) and adolescents' sexual maturation (p=0.01) was seen. Dieting and skipping meals were associated to obesity with a risk of 3.98 (95% CI: 1.83-8.67) and 2.54 (95% CI: 1.22-5.29) respectively. CONCLUSIONS: Overweight and obesity prevalences in the area studied are of concern despite adolescents' behaviors to prevent to obesity. There is a need to implement more effective campaigns to provide better guidance to adolescents.OBJETIVO: Determinar a prevalência e os fatores associados ao sobrepeso e à obesidade em adolescentes de zona urbana. MÉTODOS: Estudo transversal de base populacional, realizado no município de Pelotas, Rio Grande do Sul, de 2001 a 2002. Adolescentes entre 15 e 18 anos de idade foram medidos, pesados e responderam a questionário auto-aplicável. De 90 setores sorteados, foram visitados 86 domicílios em cada setor, totalizando 960 adolescentes. A prevalência de sobrepeso e obesidade foi definida a partir do índice de massa corporal, mediante a utilização dos pontos de corte, ajustados à idade e ao sexo. Realizou-se análise multivariada com regressão de Poisson, considerando um modelo hierárquico das variáveis associadas ao sobrepeso e à obesidade. RESULTADOS: A prevalência de sobrepeso e de obesidade foi 20,9% e 5%, respectivamente. A relação entre a obesidade e idade e escolaridade do adolescente foi inversa. Verificou-se associação de sobrepeso e obesidade com o relato de obesidade dos pais (p=0,03) e maturação sexual do adolescente (p=0,01). Os hábitos de fazer dieta e omitir refeições foram associados à obesidade, com riscos de 3,98 (IC 95%: 1,83-8,67) e 2,54 (IC 95%: 1,22-5,29), respectivamente. CONCLUSÕES: A prevalência de sobrepeso e obesidade na região são preocupantes a despeito do comportamento dos adolescentes para prevenir a obesidade. É necessária a implantação de campanhas mais eficazes, direcionadas a orientar melhor os adolescentes