3,222 research outputs found

    Toward a new social contract theory in organization science

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    Includes bibliographic references (p. 23-29)

    Comparison of epifluorescent viable bacterial count methods

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    Two methods, the 2-(4-Iodophenyl) 3-(4-nitrophenyl) 5-phenyltetrazolium chloride (INT) method and the direct viable count (DVC), were tested and compared for their efficiency for the determination of the viability of bacterial populations. Use of the INT method results in the formation of a dark spot within each respiring cell. The DVC method results in elongation or swelling of growing cells that are rendered incapable of cell division. Although both methods are subjective and can result in false positive results, the DVC method is best suited to analysis of waters in which the number of different types of organisms present in the same sample is assumed to be small, such as processed waters. The advantages and disadvantages of each method are discussed

    Numerical simulations of supersonic flow through oscillating cascade sections

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    A finite difference code was developed for modeling inviscid, unsteady supersonic flow by solution of the compressible Euler equations. The code uses a deforming grid technique to capture the motion of the airfoils and can model oscillating cascades with any arbitrary interblade phase angle. A flat plate cascade is analyzed, and results are compared with results from a small perturbation theory. The results show very good agreement for both the unsteady pressure distributions and the integrated force predictions. The reason for using the numerical Euler code over a small perturbation theory is the ability to model real airfoils that have thickness and camber. Sample predictions are presented for a cascade of loaded airfoils and show appreciable differences in the unsteady surface pressure distributions when compared with the flat plate results

    Numerical analysis of supersonic flow through oscillating cascade sections by using a deforming grid

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    A finite difference code was developed for modeling inviscid, unsteady supersonic flow by solution of the compressible Euler equations. The code uses a deforming grid technique to capture the motion of the airfoils and can model oscillating cascades with any arbitrary interblade phase angle. A flat plate cascade is analyzed, and results are compared with results from a small-perturbation theory. The results show very good agreement for both the unsteady pressure distributions and the integrated force predictions. The reason for using the numerical Euler code over a small-perturbation theory is the ability to model real airfoils that have thickness and camber. Sample predictions are presented for a section of the rotor on a supersonic throughflow compressor designed at NASA Lewis Research Center. Preliminary results indicate that two-dimensional, flat plate analysis predicts conservative flutter boundaries

    An Evaluation of a District Level Professional Development Program for School Leaders

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    This study evaluated a district-based leadership institute for effectiveness of role transition for newly appointed administrators. The researcher used a non-experimental descriptive design utilizing a mixed-method approach of qualitative and quantitative data to evaluate the program. The population surveyed included a convenience sample of 23 administrators who participated in a district-based professional development program implemented for school leaders. A survey was devised based upon Georgia Leadership Institute for School Improvement (GLISI) and Human Capital Development & Education Leader Performance Support\u27s (H-ELPS), 8 Roles Assessment-District survey. The instrument focused on the key roles of school leaders used to distinguish the type of leadership skills one possesses including; the curriculum, assessment and instruction leader, data analysis leader, relationship leader, operational/process /process leader and the change leader. The study results from the data indicated the favorability and homogenous rating of the 6 leadership domains perceived by the respondents. These findings suggest that the perception of the Leaders Institute was overall effective for the participants in the district. Overwhelmingly most participants would be willing to continue employment in the district for 5 more years as a result of the program. Follow-up studies are advised to garner higher response rates to determine if the results are similar

    Reciprocal intronic and exonic histone modification regions in humans.

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    While much attention has been focused on chromatin at promoters and exons, human genes are mostly composed of intronic sequences. Analyzing published surveys of nucleosomes and 41 chromatin marks in humans, we identified histone modifications specifically associated with 5' intronic sequences, distinguishable from promoter marks and bulk nucleosomes. These intronic marks were spatially reciprocal to trimethylated histone H3 Lys36 (H3K36me3), typically transitioning near internal exons. Several marks transitioned near bona fide exons, but not near nucleosomes at exon-like sequences. Therefore, we examined whether splicing affects histone marking. Even with considerable changes in regulated alternative splicing, histone marks were stable. Notably, these findings are consistent with exon definition influencing histone marks. In summary, we show that the location of many intragenic marks in humans can be distilled into a simple organizing principle: association with 5' intronic or 3' exonic regions

    Microbial biofilm studies of the environmental control and life support system water recovery test for Space Station Freedom

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    NASA is developing a water recovery system (WRS) for Space Station Freedom to reclaim human waste water for reuse by astronauts as hygiene or potable water. A water recovery test (WRT) currently in progress investigates the performance of a prototype of the WRS. Analysis of biofilm accumulation, the potential for microbially influenced corrosion (MIC) in the WRT, and studies of iodine disinfection of biofilm are reported. Analysis of WRT components indicated the presence of organic deposits and biofilms in selected tubing. Water samples for the WRT contained acid-producing and sulfate-reducing organisms implicated in corrosion processes. Corrosion of an aluminum alloy was accelerated in the presence of these water samples; however, stainless steel corrosion rates were not accelerated. Biofilm iodine sensitivity tests using an experimental laboratory scale recycled water system containing a microbial check valve (MCV) demonstrated that an iodine concentration of 1 to 2 mg/L was ineffective in eliminating microbial biofilm. For complete disinfection, an initial concentration of 16 mg/L was required, which was gradually reduced by the MCV over 4 to 8 hours to 1 to 2 mg/L. This treatment may be useful in controlling biofilm formation

    Analysis of debris from Spacelab Space Life Sciences-1

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    Airborne microbiological and particulate contamination generated aboard Spacelab modules is a potential safety hazard. In order to shed light on the characteristics of these contaminants, microbial and chemical/particulate analyses were performed on debris vacuumed from cabin and avionics air filters in the Space Life Sciences-1 (SLS-1) module of the Space Transportation System 40 (STS-40) mission 1 month after landing. The debris was sorted into categories (e.g., metal, nonmetal, hair/fur, synthetic fibers, food particles, insect fragments, etc.). Elemental analysis of particles was done by energy dispersive analysis of x rays (metals) and Fourier transform infrared spectroscopy (nonmetals). Scanning electron micrographs were done of most particles. Microbiological samples were grown on R2A culture medium and identified. Clothing fibers dominated the debris by volume. Other particles, all attributed to the crew, resulted from abrasions and impacts during missions operations (e.g., paint chips, plastic, electronic scraps and clothing fibers). All bacterial species identified are commonly found in the atmosphere or on the human body. Bacillus sp. was the most frequently seen bacterium. One of the bacterial species, Enterobacter agglomerans, could cause illness in crew members with depressed immune systems

    Ebola, Politics and Ecology: Beyond the ‘Outbreak Narrative’

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    The origin of the Ebola outbreak in West Africa has been traced to the likely confluence of a virus, a bat, a two-year-old child and an underequipped rural health centre. Understanding how these factors may have combined in south-eastern Guinea near the end of 2013 requires us to rethink elements of the familiar Ebola ‘outbreak narrative’, as propagated by the international media, in a deeper political, economic and ecological context. This includes examining the social, ecological and epidemiological evidence and questioning long-held and misplaced assumptions about rural resource users, rural livelihoods, deforestation and environmental change, and the role of development in both the current crisis and in realising a more resilient future. Emerging research indicates that demography, patterns of land use and of human-wildlife interaction are all implicated in zoonotic ‘spillover’ events, but cannot be generalised across cases and localities. This is because these patterns are highly contextual and variable regionally and locally due to divergent and dynamic sociopolitical, economic and ecological histories.UK Department for International Developmen

    Euler flow predictions for an oscillating cascade using a high resolution wave-split scheme

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    A compressible flow code that can predict the nonlinear unsteady aerodynamics associated with transonic flows over oscillating cascades is developed and validated. The code solves the two dimensional, unsteady Euler equations using a time-marching, flux-difference splitting scheme. The unsteady pressures and forces can be determined for arbitrary input motions, although only harmonic pitching and plunging motions are addressed. The code solves the flow equations on a H-grid which is allowed to deform with the airfoil motion. Predictions are presented for both flat plate cascades and loaded airfoil cascades. Results are compared to flat plate theory and experimental data. Predictions are also presented for several oscillating cascades with strong normal shocks where the pitching amplitudes, cascade geometry and interblade phase angles are varied to investigate nonlinear behavior
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