10,415 research outputs found
Contact urticaria to giraffe hair
Background: Immediate-type hypersensitivity to animal proteins is a common problem in people occupationally exposed to animals. Methods: A 19-year-old female working as a voluntary zookeeper in her off-time suffered from hives on her forearms following contact to the fur of a giraffe. For diagnostic evaluation, skin prick tests, assessment of specific serum IgE antibodies, and basophil activation tests were performed. Results: Skin prick tests with a standard series of common aeroallergens were positive for various pollens. Prick testing with native materials was positive for extracts of hair from two different giraffe subspecies in the patient, but not in control subjects. By CAP-FEIA, no specific serum IgE antibodies to dander of a large variety of animals were found in the patient. In the basophil activation test, expression of the activation marker CD63 was induced by extract of giraffe hair on the cells from the patient, but not on those from unaffected controls. Conclusions: This patient suffers from an `exotic' immediate-type contact allergy to giraffe hair. Copyright (C) 2005 S. Karger AG, Basel
Political Ambition and Legislative Behavior in the European Parliament
Members of the European Parliament (MEP) typically follow one of two career paths, either advancing within the European Parliament itself or returning to higher office in their home states. We argue that these different ambitions condition legislative behavior. Specifically, MEPs seeking domestic careers defect from group-leadership votes more frequently and oppose legislation that expands the purview of supranational institutions. We show how individual, domestic-party, and national level variables shape the careers available to MEPs and, in turn, their voting choices. To test the argument, we analyze MEPs' roll-call voting behavior in the 5th session of the EP (1999-2004) using a random effects model that captures idiosyncrasies in voting behavior across both individual MEPs and specific roll-call votes.published or submitted for publicationnot peer reviewe
Magnetoresistance Effects in SrFeO(3-x): Dependence on Phase Composition and Relation to Magnetic and Charge Order
Single crystals of iron(IV) rich oxides SrFeO(3-x) with controlled oxygen
content have been studied by Moessbauer spectroscopy, magnetometry,
magnetotransport measurements, Raman spectroscopy, and infrared ellipsometry in
order to relate the large magnetoresistance (MR) effects in this system to
phase composition, magnetic and charge order. It is shown that three different
types of MR effects occur. In cubic SrFeO3 (x = 0) a large negative MR of 25%
at 9 T is associated with a hitherto unknown 60 K magnetic transition and a
subsequent drop in resistivity. The 60 K transition appears in addition to the
onset of helical ordering at ~130 K. In crystals with vacancy-ordered
tetragonal SrFeO(3-x) as majority phase (x ~0.15) a coincident
charge/antiferromagnetic ordering transition near 70 K gives rise to a negative
giant MR effect of 90% at 9 T. A positive MR effect is observed in tetragonal
and orthorhombic materials with increased oxygen deficiency (x = 0.19, 0.23)
which are insulating at low temperatures. Phase mixtures can result in a
complex superposition of these different MR phenomena. The MR effects in
SrFeO(3-x) differ from those in manganites as no ferromagnetic states are
involved
Inductive effects in neighboring-group participation. Destabilization of carbocations by CC double bonds in solvolyses of 2,2,5,5-tetramethylcyclopent-3-en-1-yl tosylates
New developments in the management of major depressive disorder and generalized anxiety disorder: role of quetiapine
Quetiapine has demonstrated efficacy in schizophrenia, bipolar disorder and in the treatment of specific symptom clusters such as agitation and sleep problems in mood disorders. In this review, randomized controlled studies demonstrating efficacy, safety and tolerability of quetiapine in major depressive disorder (MDD) and general anxiety disorder (GAD) are evaluated. The results show that quetiapine monotherapy and quetiapine augmentation of antidepressant treatment in MDD and GAD are efficacious for short-term and maintenance treatment at a dose range between 50 and 300 mg/day. Quetiapine appears to have a specific but overall mild side-effect profile, though, some adverse effects such as sedation and somnolence may lead to withdrawal from treatment in some patients. Overall, the available evidence suggests that there is a significant role for quetiapine in the treatment of MDD and GAD
The development of AIDS policy in Thailand: the factors influencing the policy development process from 1984 to 1993
Master of ArtsCenter for Southeast Asian StudiesUniversity of Michiganhttps://deepblue.lib.umich.edu/bitstream/2027.42/149091/1/013850105.pd
Enzyme-linked immunosorbent assay for urinary albumin at low concentrations
We describe an enzyme-linked immunosorbent assay (ELISA) for urinary albumin. It requires only commercially available reagents, can detect as little as 16 micrograms of albumin per liter, and analytical recovery ranges from 92 to 116%. The assay is simple, rapid, and inexpensive. Albumin excretion was 6.2 (SD 4.1) mg/24 h in healthy subjects (n = 40), 14.7 (SD 7.2) mg/24 h in albumin-test-strip-negative Type I diabetics (n = 11), and 19.7 (SD 16.2) mg/24 h in patients with essential hypertension (n = 12)
Unconventional conductance plateau transitions in quantum Hall wires with spatially correlated disorder
Quantum transport properties in quantum Hall wires in the presence of
spatially correlated random potential are investigated numerically. It is found
that the potential correlation reduces the localization length associated with
the edge state, in contrast to the naive expectation that the potential
correlation increases it. The effect appears as the sizable shift of quantized
conductance plateaus in long wires, where the plateau transitions occur at
energies much higher than the Landau band centers. The scale of the shift is of
the order of the strength of the random potential and is insensitive to the
strength of magnetic fields. Experimental implications are also discussed.Comment: 5 pages, 4 figure
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