101 research outputs found
I support sustainability but only when doing so reflects fabulously on me: can green narcissists be cultivated?
Sustainability research has coalesced around the notion that many environmental problems can be framed as social dilemmas in which conflicts often arise between consumers’ pursuit of individual, short-term and self-directed goals and their support for collective, long-term and socially-oriented interests. The need to address this challenge is simultaneously becoming more important and challenging for macromarketers and policy makers as the incidence of individualistic consumer traits (e.g., narcissism and self-esteem), already high in general population, continues to grow throughout Western societies. This article examines why and how such individualistic tendencies (here, narcissistic exhibitionism) may impact consumers’ pro-environmental behavior. This research identifies an underlying mechanism (i.e., altruism) for the proposed effect. The potential effects of manageable boundary conditions for this relationship are also proposed and tested across four studies
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Impact of 13-valent pneumococcal conjugate vaccine (PCV13) in a pandemic similar to the 2009 H1N1 in the United States
Background: High rates of bacterial coinfection in autopsy data from the 2009 H1N1 influenza (“flu”) pandemic suggest synergies between flu and pneumococcal disease (PD) during pandemic conditions, and highlight the importance of interventions like the 13-valent pneumococcal conjugate vaccine (PCV13) that may mitigate the impact of a pandemic. Methods: We used a decision-analytic model, estimated from published sources, to assess the impact of pediatric vaccination with PCV13 versus the 7-valent vaccine (PCV7) on PD incidence and mortality in a normal flu season (10% flu incidence) and in a pandemic similar to 2009-2010 H1N1 (20% flu incidence, mild virulence, high impact in children). Both direct and indirect (herd) effects against PD were considered. Effectiveness of PCV13 was extrapolated from observed PCV7 data, using assumptions of serotype prevalence and PCV13 protection against the 6 serotypes not in PCV7. To simulate 2009–2010 H1N1, autopsy data were used to estimate the overall proportion of flu deaths with bacterial coinfections. By assuming that increased risk of death during the pandemic occurred among those with comorbidity (using obesity as proxy) and bacterial coinfections primarily due to S. pneumoniae or S. aureus, we estimated the proportion co-infected among all (fatal and non-fatal) flu cases (7.6% co-infected with any organism; 2.2% with S. pneumoniae). PD incidence, mortality, and total healthcare costs were evaluated over a 1-year horizon. Results: In a normal flu season, compared to PCV7, PCV13 is expected to prevent an additional 13,400 invasive PD (IPD) cases, 399,000 pneumonia cases, and 2,900 deaths, leading to cost savings of 1.0 B compared to PCV7. Conclusions: In a flu pandemic similar to the 2009–2010 H1N1, protection against the 6 additional serotypes in PCV13 would likely be effective in preventing pandemic-related PD cases, mortality, and associated costs
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Modeling the impact of the 13-valent pneumococcal conjugate vaccine serotype catch-up program using United States claims data
Background: Analysis of US claims data from April 2010 to June 2011 estimated that 39% of the 13-valent pneumococcal conjugate vaccine (PCV13) catch-up eligible cohort would ever receive the catch-up vaccination; a previous analysis assumed 87%. Methods: This updated figure was applied to a previously published 10-year Markov model while holding all other inputs constant. Results: Our model estimated that the catch-up program as currently implemented is estimated to prevent an additional 1.7 million cases of disease in children aged ≤59 months over a 10-year period, compared with routine PCV13 vaccination with no catch-up program. Conclusions: Because 39% catch-up uptake is less than the level of completion of the 4-dose primary PCV13 series, vaccine-preventable cases of pneumococcal disease and related deaths could be decreased further with additional uptake of catch-up vaccination in the catch-up eligible cohort
Phenological changes of oceanic phytoplankton in the 1980s and 2000s as revealed by remotely sensed ocean-color observations
We investigated the phenology of oceanic phytoplankton at large scales over two 5-year time periods: 1979–1983 and 1998–2002. Two ocean-color satellite data archives (Coastal Zone Color Scanner (CZCS) and Sea-viewing Wide Field-of-view Sensor (SeaWiFS)) were used to investigate changes in seasonal patterns of concentration-normalized chlorophyll. The geographic coverage was constrained by the CZCS data distribution. It was best for the Northern Hemisphere and also encompassed large areas of the Indian, South Pacific, and Equatorial Atlantic regions. For each 2° pixel, monthly climatologies were developed for satellite-derived chlorophyll, and the resulting seasonal cycles were statistically grouped using cluster analysis. Five distinct groups of mean seasonal cycles were identified for each half-decade period. Four types were common to both time periods and correspond to previously identified phytoplankton regimes: Bloom, Tropical, Subtropical North, and Subtropical South. Two other mean seasonal cycles, one in each of the two compared 5-year periods, were related to transitional or intermediate states (Transitional Tropical and Transitional Bloom). Five mean seasonal cycles (Bloom, Tropical, Subtropical North, and Subtropical South, Transitional Bloom) were further confirmed when the whole SeaWiFS data set (1998–2010) was analyzed. For ~35% of the pixels analyzed, characteristic seasonal cycles of the 1979–1983 years differed little from those of the 1998–2002 period. For ~65% of the pixels, however, phytoplankton seasonality patterns changed markedly, especially in the Northern Hemisphere. Subtropical regions of the North Pacific and Atlantic experienced a widespread expansion of the Transitional Bloom regime, which appeared further enhanced in the climatology based on the full SeaWiFS record (1998–2010), and, as showed by a more detailed analysis, is associated to La Niña years. This spatial pattern of Transitional Bloom regime reflects a general smoothing of seasonality at macroscale, coming into an apparent greater temporal synchrony of the Northern Hemisphere. The Transitional Bloom regime is also the result of a higher variability, both in space and time. The observed change in phytoplankton dynamics may be related not only to biological interactions but also to large-scale changes in the coupled atmosphere–ocean system. Some connections are indeed found with climate indices. Changes were observed among years belonging to opposite phases of ENSO, though discernible from the change among the two periods and within the SeaWiFS era (1998–2010). These linkages are considered preliminary at present and are worthy of further investigation
Neurophysiologic effects of spinal manipulation in patients with chronic low back pain
<p>Abstract</p> <p>Background</p> <p>While there is growing evidence for the efficacy of SM to treat LBP, little is known on the mechanisms and physiologic effects of these treatments. Accordingly, the purpose of this study was to determine whether SM alters the amplitude of the motor evoked potential (MEP) or the short-latency stretch reflex of the erector spinae muscles, and whether these physiologic responses depend on whether SM causes an audible joint sound.</p> <p>Methods</p> <p>We used transcranial magnetic stimulation to elicit MEPs and electromechanical tapping to elicit short-latency stretch reflexes in 10 patients with chronic LBP and 10 asymptomatic controls. Neurophysiologic outcomes were measured before and after SM. Changes in MEP and stretch reflex amplitude were examined based on patient grouping (LBP vs. controls), and whether SM caused an audible joint sound.</p> <p>Results</p> <p>SM did not alter the erector spinae MEP amplitude in patients with LBP (0.80 ± 0.33 vs. 0.80 ± 0.30 μV) or in asymptomatic controls (0.56 ± 0.09 vs. 0.57 ± 0.06 μV). Similarly, SM did not alter the erector spinae stretch reflex amplitude in patients with LBP (0.66 ± 0.12 vs. 0.66 ± 0.15 μV) or in asymptomatic controls (0.60 ± 0.09 vs. 0.55 ± 0.08 μV). Interestingly, study participants exhibiting an audible response exhibited a 20% decrease in the stretch reflex (p < 0.05).</p> <p>Conclusions</p> <p>These findings suggest that a single SM treatment does not systematically alter corticospinal or stretch reflex excitability of the erector spinae muscles (when assessed ~ 10-minutes following SM); however, they do indicate that the stretch reflex is attenuated when SM causes an audible response. This finding provides insight into the mechanisms of SM, and suggests that SM that produces an audible response may mechanistically act to decrease the sensitivity of the muscle spindles and/or the various segmental sites of the Ia reflex pathway.</p
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Harmful algal blooms along the North American west coast region: History, trends, causes, and impacts
Along the Pacific coast of North America, from Alaska to Mexico, harmful algal blooms (HABs) have caused losses to natural resources and coastal economies, and have resulted in human sicknesses and deaths for decades. Recent reports indicate a possible increase in their prevalence and impacts of these events on living resources over the last 10–15 years. Two types of HABs pose the most significant threat to coastal ecosystems in this “west coast” region: dinoflagellates of the genera Alexandrium, Gymnodinium, and Pyrodinium that cause paralytic shellfish poisoning (PSP) and diatoms of the genus Pseudo-nitzschia that produce domoic acid (DA), the cause of amnesic shellfish poisoning (ASP) in humans. These species extend throughout the region, while problems from other HABs (e.g., fish kills linked to raphidophytes or Cochlodinium, macroalgal blooms related to invasive species, sea bird deaths caused by surfactant-like proteins produced by Akashiwo sanguinea, hepatotoxins from Microcystis, diarrhetic shellfish poisoning from Dinophysis, and dinoflagellate-produced yessotoxins) are less prevalent but potentially expanding. This paper presents the state-of-knowledge on HABs along the west coast as a step toward meeting the need for integration of HAB outreach, research, and management efforts.Keywords: Alexandrium, Harmful algal blooms, Pseudo-nitzschia, Domoic acid, Paralytic shellfish poisoning, Heterosigm
Public health and economic impact of vaccination with 7-valent pneumococcal vaccine (PCV7) in the context of the annual influenza epidemic and a severe influenza pandemic
Background: Influenza pandemic outbreaks occurred in the US in 1918, 1957, and 1968. Historical evidence suggests that the majority of influenza-related deaths during the 1918 US pandemic were attributable to bacterial pneumococcal infections. The 2009 novel influenza A (H1N1) outbreak highlights the importance of interventions that may mitigate the impact of a pandemic. Methods: A decision-analytic model was constructed to evaluate the impact of 7-valent pneumococcal conjugate vaccine (PCV7) on pneumococcal disease incidence and mortality during a typical influenza season (13/100) and a severe influenza pandemic (30/100). Outcomes were compared for current PCV7 vaccination practices vs. no vaccination. The model was estimated using published sources and includes indirect (herd) protection of non-vaccinated persons. Results: The model predicts that PCV7 vaccination in the US is cost saving for a normal influenza season, reducing pneumococcal-related costs by 7.3 billion in costs and prevent 512,000 cases of IPD, 719,000 cases of pneumonia, 62,000 IPD deaths, and 47,000 pneumonia deaths; 84% of deaths are prevented due to indirect (herd) protection in the unvaccinated. Conclusions: PCV7 vaccination is highly effective and cost saving in both normal and severe pandemic influenza seasons. Current infant vaccination practices may prevent >1 million pneumococcal-related deaths in a severe influenza pandemic, primarily due to herd protection
Seafarer citizen scientist ocean transparency data as a resource for phytoplankton and climate research
The oceans' phytoplankton that underpin the marine food chain appear to be changing in abundance due to global climate change. Here, we compare the first four years of data from a citizen science ocean transparency study, conducted by seafarers using home-made Secchi Disks and a free Smartphone application called Secchi, with contemporaneous satellite ocean colour measurements. Our results show seafarers collect useful Secchi Disk measurements of ocean transparency that could help future assessments of climate-induced changes in the phytoplankton when used to extend historical Secchi Disk data
“Managing through Failure”: More than an Oxymoron?
This article includes observations and principles to assist managers in their efforts to lead subordinates and themselves through failure
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