9 research outputs found
Customer-focused product development : An outdoor industry perspective
Being customerâfocused is often considered to be a key success factor inproductâ or service development. This kind of approach may comprise manythings in practice, such as formal or informal methods and activities that arecarried out to identify and meet, or preferably exceed, customer needs andexpectations. The overall purpose of this thesis is to contribute to a greaterknowledge about the use and function of methods, activities and tools regardingcustomerâfocused product development in the outdoor industry.The thesis is based on three papers, all related to customerâfocused productdevelopment within the outdoor industry. Two empirical studies have beenconducted. In the first one, the outdoor companiesâ own experiences of customerinvolvement in product development are examined. In the second study, the useand function of environmental labels as drivers of attractive quality within theoutdoor industry are explored.A new methodology for customerâfocused product development is alsopresented. It is aimed to be used as a handsâon support for designing for thesatisfaction of customer needs at different levels in practice, especially those thathave been found to be important in the creation of attractive quality and customerloyalty
Designing for the satisfaction of high-level needs : introducing the Ideation Need Mapping (INM) methodology
Purposeâ The purpose of this paper is to introduce a methodology that can support the process of understanding and designing for the satisfaction of high-level needs in practice. The satisfaction of high-level needs has seldom been in focus when it comes to customer satisfaction surveys or the process of new product or service development. However, needs do occur on various levels, and the satisfaction of high-level needs actually appears to have the greatest potential for the creation of loyalty among customers and customer satisfaction. The satisfaction of high-level needs has furthermore been pointed out as a strategy for the creation of attractive quality.Design/methodology/approachâ The paper is based on literature studies and the application of the Ideation Need Mapping (INM) methodology in a specific case.Findingsâ The paper presents the INM methodology that could be used for guiding product and service innovation in practice. More specifically, the methodology supports the process of understanding and designing for the satisfaction of high-level needs.Originality/valueâ This paper aims to contribute to envisioning and demonstrating how the understanding of, and design for, satisfaction of high-level needs can be done in practice
FrÄn Paris till Ragunda : En översikt av processen att överföra Parisavtalet till kommunal aktion
Syftet med denna rapport Ă€r att belysa processen att föra över det internationella Paris-klimatavtalet frĂ„n 2015 till först nationell nivĂ„ och sedan vidare till regional (JĂ€mtlands lĂ€n) och slutligen till kommunal nivĂ„ (Ragunda). Avsikten med rapporten Ă€r inte att med precision analysera situationen, utan vĂ„r ambition Ă€r snarare att lyfta fram olika frĂ„gestĂ€llningar som kan utgöra en grund för fortsatt reflektion och diskussion. SvĂ„righeterna att möta kraven pĂ„ kontinuerlig reduktion av klimatrelaterade utslĂ€pp Ă€r omfattande och lösningsvĂ€garna Ă€nnu delvis okĂ€nda, vilket i sig gör att man mĂ„ste uppvisa stor uthĂ„llighet med ett mycket lĂ„ngsiktigt arbete. Vi har inom ramen för Interreg-projekt SMICE[1] deltagit i arbetet med framtagandet av Region JĂ€mtland HĂ€rjedalens Energi- och klimatstrategi för 2020-2030, vid lanseringen av densamma samt i nĂ€rmare dialog med representanter för en av Ă„tta kommuner i regionen, Ragunda kommun. Vad gĂ€ller Ragunda kommun kan studien inte pĂ„visa nĂ„gon förĂ€ndring i kommunens styrning och pĂ„verkan i den ekonomiska styrningen, detta gĂ€ller för kommunens budget för 2020 samt det pĂ„gĂ„ende budgetarbetet för 2021. Intentionerna i energi- och klimatstrategin visar sig Ă€nnu inte i nĂ„gon större utstrĂ€ckning i kommunens verksamhet, trots en vilja bland politiker och tjĂ€nstemĂ€n att bidra till mĂ„luppfyllelse. De förĂ€ndringar som beslutsfattare önskar ske i vĂ„rt samhĂ€lle bromsas i den kommunala kontexten av en rad hindrande faktorer. En slutsats frĂ„n rapporten Ă€r att det finns en klar prioriteringsproblematik mellan klimatrelaterade mĂ„l och rena vĂ€lfĂ€rdsmĂ„l. Det som ytterligare förvĂ€rrar denna problematik Ă€r att förutsĂ€ttningar för kollektiva samverkanslösningar i glesbygd Ă€r sĂ€mre jĂ€mfört med förutsĂ€ttningarna för tĂ€tbefolkade omrĂ„den. En annan slutsats Ă€r att det Ă€r svĂ„rt att svara pĂ„ frĂ„gan vilken insats eller aktivitet som Ă€r mest klimatoptimal. Ofta beror svaret pĂ„ hur frĂ„gan stĂ€lls. Denna problematik gör att det kan vara svĂ„rt att pĂ„ kommunal nivĂ„ ta beslut som faktiskt gynnar klimatet och miljön pĂ„ bĂ„de kort och lĂ„ng sikt. [1][1] Samskapande Mittnordisk Innovationsarena för CirkulĂ€r Ekonomi (SMICE) Ă€r ett Interreg projekt med syfte att hitta sĂ€tt att accelerera omstĂ€llningen i JĂ€mtland-HĂ€rjedalen och Tröndelag mot âett grönt skifteâ. Projektet har utforskat samskapande och har med en bred ansats sökt sammankoppla nĂ€ringsliv, medborgare och aktörer i innovationssystemet för att utveckla aktiviteter som stĂ€rker cirkulĂ€ra ekonomi. Projektettid har pĂ„gĂ„tt perioden 2017â2020
More value from fewer resources : How to expand value stream mapping with ideas from circular economy
Purpose: The purpose of this paper is to discuss recent trends in the circular economy and investigate how value stream mapping (VSM) can be extended to more fully include some of the critical aspects of circular economy. Design/methodology/approach: The findings are based on previous research that has explored the usage of VSM to include aspects of the environment and sustainability aspects. These ideas are then expanded to new ways to use VSM by mapping value of a product as it is; used, maintained, re-used, remanufactured, recycled, incinerated or used for landfill. The authors test out this approach through application in the waste management sector to identify possibilities for improvement and new business opportunities in what now is considered waste. Findings: This paper introduces an expanded version of VSM that refines the existing Lean toolbox for exploring value and mapping value in a circular economy. Practical implications: The aim of this paper is to expand the relevance and practical value of VSM as the world economy increasingly moves toward a circular one. Originality/value: Today, VSM is a widespread method within Lean manufacturing that scrutinizes value creation within an organization or within a value chain. This paper describes how VSM can be refined to explore value streams in the afterlife of a product and explore waste as a resource utilization opportunity
Customer involvement in product development: experiences from Scandinavian outdoor companies
In this paper the outdoor gear and clothing companieĆ experiences ofcustomerinvolvement in product development are investigated and discussed. The purpose is to examine howcustomersare involved in product development and whether the companies believe there is a need for greater involvement. The study focuses on threecustomergroups: users, retailers and professional users. Surveys were sent out to 33 Swedish and Norwegian companies within the Scandinavian Outdoor Group. The results of the study indicate that the companies think there is a need to involve the users more than today in the early phases of the product development process. Smaller companies seem to have a need for greater user involvement. Most of the participants also explained that they would increase theircustomerinvolvement if they had more time and greater financial resources. © 2011 Published by Elsevier Ltd
Kokbok för förÀndringsledare : Metdoder för att stötta engagerade mÀnniskor att förverkliga idéer
Det hÀr Àr en kokbok för förÀndringsledare. Du kan anvÀnda denna bok om du ska leda  utvecklingsaktiviteter och letar efter bra och beprövade metoder för att leda grupper  och processer. Vi beskriver metoderna som vi har anvÀnt inom vÄrt projekt SMICE, i  vilket sammanhang metoderna anvÀnts och nÀr de olika metoderna fungerat bra. VÄr förhoppning med att nedteckna dessa metoder Àr att du ska inspireras och vÄgar  prova nÄgot nytt för att skapa nytta. Vi tror att ett detaljerat sÀtt att dokumentera  metoderna gör dem mer anvÀndbara för dig men ocksÄ för oss sjÀlva.  Metoderna Àr graderade efter vilket behov av förkunskap och förberedelser du behöver,  frÄn det enklaste, dÀr du kan öppna kokboken och anvÀnda metoden pÄ en gÄng, till  metoder som krÀver utbildning eller specialistkompetens innan du sÀtter igÄng. Boken Àr indelad i fyra huvuddelar; Starta, Forma, Utveckla och förankra och Bygga vidare. Till dessa delar har vi identifierat metodstöd som kan anvÀndas vid en rad olika tillfÀllen;  vid idégenerering, vid idéutveckling, vid affÀrsutveckling, för att inspirera, för att skapa  samsyn och samverkan och för att mobilisera större grupper av mÀnniskor och  organisationer. NÄgot för alla, alltsÄ. Avslutningsvis finner du tips och stöd för att  driva dessa utvecklingsprocesser pÄ distans med digitala verktyg i digitala möten. Ska vi sammanfatta nÄgon lÀrdom av detta arbete sÄ blir det vÄra nycklar som presenteras pÄ nÀsta sida. Du kan se dessa nycklar som vÄra bÀsta rÄd för att du ska lyckas med ditt  arbete med att leda processer och att ordna möten. Lycka till! Metoderna har testats och utvecklats inom SMICE - Samskapande Mittnordisk  Innovationsarena för CirkulÀr Ekonomi, ett projekt inom Interreg som pÄgÄtt  2017-2020.
Deubiquitinase inhibition by WP1130 leads to ULK1 aggregation and blockade of autophagy
<p>Autophagy represents an intracellular degradation process which is involved in both regular cell homeostasis and disease settings. In recent years, the molecular machinery governing this process has been elucidated. The ULK1 kinase complex consisting of the serine/threonine protein kinase ULK1 and the adapter proteins ATG13, RB1CC1, and ATG101, is centrally involved in the regulation of autophagy initiation. This complex is in turn regulated by the activity of different nutrient- or energy-sensing kinases, including MTOR, AMPK, and AKT. However, next to phosphorylation processes it has been suggested that ubiquitination of ULK1 positively influences ULK1 function. Here we report that the inhibition of deubiquitinases by the compound WP1130 leads to increased ULK1 ubiquitination, the transfer of ULK1 to aggresomes, and the inhibition of ULK1 activity. Additionally, WP1130 can block the autophagic flux. Thus, treatment with WP1130 might represent an efficient tool to inhibit the autophagy-initiating ULK1 complex and autophagy.</p
SLC9A6 Mutations Cause X-Linked Mental Retardation, Microcephaly, Epilepsy, and Ataxia, a Phenotype Mimicking Angelman Syndrome
Linkage analysis and DNA sequencing in a family exhibiting an X-linked mental retardation (XLMR) syndrome, characterized by microcephaly, epilepsy, ataxia, and absent speech and resembling Angelman syndrome, identified a deletion in the SLC9A6 gene encoding the Na+/H+ exchanger NHE6. Subsequently, other mutations were found in a male with mental retardation (MR) who had been investigated for Angelman syndrome and in two XLMR families with epilepsy and ataxia, including the family designated as having Christianson syndrome. Therefore, mutations in SLC9A6 cause X-linked mental retardation. Additionally, males with findings suggestive of unexplained Angelman syndrome should be considered as potential candidates for SLC9A6 mutations