4,855 research outputs found
Proposal for an Integrated Raman-free Correlated Photon Source
We propose a dual-pump third-order nonlinear scheme for producing pairs of
correlated photons that is less susceptible to Raman noise than typical
spontaneous four wave mixing methods (SFWM). Beginning with the full multimode
Hamiltonian we derive a general expression for the joint spectral amplitude,
from which the probability of producing a pair of photons can be calculated. As
an example, we demonstrate that a probability of 0.028 pairs per pulse can be
achieved in an appropriately designed fused silica microfiber. As compared with
single pump SFWM in standard fiber, we calculate that our process shows
significant suppression of the spontaneous Raman scattering and an improvement
in the signal to noise ratio.Comment: 7 pages, 3 figures (two containing 2 subfigures
The growth kinetics of xenografts of human colorectal tumours in immune deprived mice.
The technique of labelled mitoses was used to examine cell proliferation within grafts of human colonic and rectal tumours in immune deprived mice. Most of the data were obtained on the first passage but in some cases up to the third passage was used. It was found to be difficult to obtain precise kinetic data on this type of tumour material, but the results did allow some estimates to be made, particularly of the duration of the G2 and S phases of the mitotic cycle. The average G2 duration was 6 h and the average S phase was 14 h. It is concluded that whilst xenografts may differ in a number of respects from the tumour in the patient, they nevertheless constitute a type of experimental tumour that is worthy of further study
Attacking Group Protocols by Refuting Incorrect Inductive Conjectures
Automated tools for finding attacks on flawed security protocols often fail to deal adequately with group protocols. This is because the abstractions made to improve performance on fixed 2 or 3 party protocols either preclude the modelling of group protocols all together, or permit modelling only in a fixed scenario, which can prevent attacks from being discovered. This paper describes Coral, a tool for finding counterexamples to incorrect inductive conjectures, which we have used to model protocols for both group key agreement and group key management, without any restrictions on the scenario. We will show how we used Coral to discover 6 previously unknown attacks on 3 group protocols
High intrinsic radiosensitivity of a newly established and characterised human embryonal rhabdomyosarcoma cell line.
A new human rhabdomyosarcoma cell line (HX170c) has been established from a paratesticular embryonal tumour in a 5-year-old male. The cells grew as an adherent monolayer with a doubling time of 32 h and showed pleomorphic features. Intermediate filament analysis revealed the line to be mesenchymal in origin (reactivity to vimentin and desmin antibodies). The line was tumorigenic in nude mice, possessed elevated levels of creatine phosphokinase (mainly of the MM isoenzyme form) and had a near diploid mean chromosome number of 50. In vitro cell cloning determinations gave colony forming efficiencies of 0.01% in soft agar and 24% in a monolayer anchorage-dependent assay. Radiosensitivity determinations using a monolayer clonogenic assay with feeder layer support showed the cells to be among the more radiosensitive human tumour cell types (surviving fraction at 2 Gy of 0.26) that have been investigated. Furthermore, experiments utilising continuous low dose rate radiation at 3.2 cGy min-1, showed that, under these experimental conditions, the cells possessed only a very low capacity to recover from radiation-induced damage (dose reduction factor at 1% cell survival of 1.07 for 150 versus 3.2 cGy min-1). As other human tumour cells of an embryonal cell origin (e.g. neuroblastoma and germ cell tumours of the testis) have also been shown to be radiosensitive it appears that sensitivity to radiation may be a common property of this group of tumours
- ā¦