3,096 research outputs found
Numerical simulation of solar coronal magnetic fields
Many aspects of solar activity are believed to be due to the stressing of the coronal magnetic field by footpoint motions at the photosphere. The results are presented of a fully spectral numerical simulation which is the first 3-D time dependent simulation of footpoint stressing in a geometry appropriate for the corona. An arcade is considered that is initially current-free and impose a smooth footpoint motion that produces a twist in the field of approx 2 pi. The footprints were fixed and the evolution was followed until the field relaxes to another current-free state. No evidence was seen for any instability, either ideal or resistive and no evidence for current sheet formation. The most striking feature of the evolution is that in response to photospheric motions, the field expands rapidly upward to minimize the stress. The expansion has two important effects. First, it suppresses the development of dips in the field that could support dense, cool material. For the motions assumed, the magnetic field does not develop a geometry suitable for prominence formation. Second, the expansion inhibits ideal instabilities such as kinking. The results indicate that simple stearing of a single arcade is unlikely to lead to solar activity such as flares or prominences. Effects are discussed that might possibly lead to such activity
First Scientific Results From The Infrared Astronomical Satellite (IRAS)
The Infrared Astronomical Satellite (IRAS) was successfully launched on 25 January 1983 and terminated science data acquisition on 22 November 1983. The in-orbit performance of the telescope has been described in two previous papers in these proceedings. A previous description of very preliminary scientific results from the mission has been given in these proceedings, while far more extensive reports have been given elsewhere. In this paper we will summarize some of the results obtained to date from the IRAS data. The work to date has sampled only a small fraction of the IRAS data; the study of the data from the IRAS survey will continue for many years to come
A New Brief Measure of Oral Quality of Life
INTRODUCTION. We developed a brief measure of the impact of oral conditions on individual functioning and well-being, known as oral quality of life. METHODS. Among older male veterans (N = 827) and community dental patients (N = 113), we administered surveys consisting of extant oral quality of life items, using clinical dental data from the veteran samples. We assigned each oral quality of life item to a theoretical dimension, conducted an iterative series of multitrait scaling analyses to examine the item-fit with the dimensions, reduced the number of items, and examined the psychometric characteristics of new scales and their association with clinical indices. RESULTS. We developed two brief oral quality of life scales, one consisting of 12 items and the other of 6, the latter a subset of the former. Each demonstrated sound psychometric properties and was sensitive to clinical indices. CONCLUSION. The two brief oral quality of life scales can be used to assess the population-based impact of oral conditions as well as outcomes of dental care.National Institute of Dental and Craniofacial Research (U54 DE14264-02); U.S. Department of Veterans Affairs Health Services Research and Development Service (IIR 93.025, HFP 91-012, RCS 02-066-1), National Institutes of Health (U54 DE014264, K24 DE000419, K24 DE018211
Clinical features, anaesthetic management and perioperative complications seen in three horses with pheochromocytoma
Three horses presenting with colic signs to the Equine Referral Hospital at The Royal Veterinary College underwent general anaesthesia between September 2013 and November 2017 for emergency exploratory laparotomy. No obvious cause for the colic signs was identified in two horses, while a haemoperitoneum was identified in the third. All horses were euthanased within 12 hours of surgery due to deteriorating haemodynamic instability and/or intractable pain. Postmortem examination revealed an adrenal mass in each case, confirmed to be a pheochromocytoma on histopathology. In retrospect, each horse had some hallmark characteristics consistent with a functional pheochromocytoma, including hyperglycaemia and hyperlactataemia. Extremely high packed cell volume (PCV) (>65 per cent) was also identified in two horses, with a high-normal PCV found in the haemoperitoneum case. Perioperative haemodynamic instability was predominantly characterised by episodes of intermittent hypertension and tachycardia
Protocol for a prospective double-blind, randomised, placebo-controlled feasibility trial of octreotide infusion during liver transplantation
Introduction Liver transplantation is a complex operation that can provide significant improvements in quality of life and survival to the recipients. However, serious complications are common and include major haemorrhage, hypotension and renal failure. Blood transfusion and the development of acute kidney injury lead to both short-term and long-term poor patient outcomes, including an increased risk of death, graft failure, length of stay and reduced quality of life. Octreotide may reduce the incidence of renal dysfunction, perioperative haemorrhage and enhance intraoperative blood pressure. However, octreotide does have risks, including resistant bradycardia, hyperglycaemia and hypoglycaemia and QT prolongation. Hence, a randomised controlled trial of octreotide during liver transplantation is needed to determine the cost-efficacy and safety of its use; this study represents a feasibility study prior to this trial.
Methods and analysis We describe a multicentre, double-blind, randomised, placebo-controlled feasibility study of continuous infusion of octreotide during liver transplantation surgery. We will recruit 30 adult patients at two liver transplant centres. A blinded infusion during surgery will be administered in a 2:1 ratio of octreotide:placebo. The primary outcomes will determine the feasibility of this study design. These include the recruitment ratio, correct administration of blinded study intervention, adverse event rates, patient and clinician enrolment refusal and completion of data collection. Secondary outcome measures of efficacy and safety will help shape future trials by assessing potential primary outcome measures and monitoring safety end points. No formal statistical tests are planned. This manuscript represents study protocol number 1.3, dated 2 June 2021.
Ethics and dissemination This study has received Research Ethics Committee approval. The main study outcomes will be submitted to an open-access journal.
Trial sponsor The Joint Research Office, University College London, UK.
Neither the sponsor nor the funder have any role in study design, collection, management, analysis and interpretation of data, writing of the study report or the decision to submit the report for publication.
Trial registration The study is registered with ClinicalTrials.gov (NCT04941911) with recruitment due to start in August 2021 with anticipated completion in July 2022.
Clinical trials unit Surgical and Interventional Group, Division of Surgery & Interventional Science, University College London
Super-Poincare' algebras, space-times and supergravities (I)
A new formulation of theories of supergravity as theories satisfying a
generalized Principle of General Covariance is given. It is a generalization of
the superspace formulation of simple 4D-supergravity of Wess and Zumino and it
is designed to obtain geometric descriptions for the supergravities that
correspond to the super Poincare' algebras of Alekseevsky and Cortes'
classification.Comment: 29 pages, v2: minor improvements at the end of Section 5.
The Mersey Estuary : sediment geochemistry
This report describes a study of the geochemistry of
the Mersey estuary carried out between April 2000 and
December 2002. The study was the first in a new programme
of surveys of the geochemistry of major British estuaries
aimed at enhancing our knowledge and understanding of the
distribution of contaminants in estuarine sediments.
The report first summarises the physical setting, historical
development, geology, hydrography and bathymetry of the
Mersey estuary and its catchment. Details of the sampling
and analytical programmes are then given followed by a
discussion of the sedimentology and geochemistry. The
chemistry of the water column and suspended particulate
matter have not been studied, the chief concern being with
the geochemistry of the surface and near-surface sediments
of the Mersey estuary and an examination of their likely
sources and present state of contamination
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