The Strategic Factors of Knowledge Management Success in Achieving Organizational Agility on the Model (APQC) (Case study: Automotive-Related Companies)

In this paper, various models were offered in the field of critical success factors for knowledge management. The quality and efficiency of America (APQC) that includes five factors of knowledge sharing culture, senior management perspective, teaching and learning, information technologies and reservoir maintenance documents were selected to check the status of organizational agility in the organization of the guidelines presented in this context. The agility of the organization was to check the status of Zhang honest. In this study, questionnaires were used to collect the information and the reliability of the questionnaire was checked through Cronbach's alpha and the reliability of organizational agility questionnaire was obtained 0.946 and knowledge management questionnaire reliability was 0.989. The study population were managers, experts and employees of Company A in the automotive industry. The company had 1400 members and 91 subjects were selected as sample by sampling method. The questionnaires provided by the two models were randomly distributed among them. The regression analysis showed that in separate relationship with the agility of these factors, the five factors were effective in achieving organizational agility, but at the same time examining these factors, only three factors including senior management perspectives, learning and container's documents, and the agility of effective organization played a role

Investigation of mutations in exons 19-23 MYH7 gene in hypertrophic cardiomyopathy patients using PCR-SSCP/HA technique in Chaharmahal va Bakhtiari province

زمینه و هدف: کاردیومایوپاتی هایپرتروفی (HCM) رایج ترین نوع از بیماری های قلبی است که 2/0 درصد از جمعیت جهان را تحت تأثیر قرار داده و همچنین رایج ترین علت مرگ قلبی ناگهانی در جوانان زیر 35 سال است. حدود 35 درصد موارد بیماری مربوط به اگزون های 24- 8 از ژن MYH7 است. هدف این مطالعه بررسی احتمال حضور جهش های مربوط به ژن MYH7 در اگزون های 23-19 در بیماران HCM استان چهارمحال و بختیاری بود. روش بررسی: در این مطالعه تجربی 30 بیمار مبتلا به HCM به روش نمونه گیری آسان از بین مراجعین به کلینیک قلب دانشگاه علوم پزشکی شهرکرد انتخاب شدند. در این بیماران DNAبه روش استاندارد فنل-کلروفرم استخراج شد. اگزون های مورد نظر با استفاده از روش PCR تکثیر و با روش SSCP به صورت تک رشته تبدیل شد و همراه نمونه های دو رشته ای روی ژل پلی آکریل آمید الکتروفورز گردید. سپس باندهای مشکوک تعیین توالی گردید و نتایج با استفاده از نرم افزار Chromas تجزیه و تحلیل شدند. یافته ها: در اگزون های 20، 21 و 23 تغییری مشاهده نشد، اما در اگزون های 19 و 22 دو جهش R719W و R870H یافت شد که به ترتیب در دو و یک نفر از بیماران وجود داشتند. نتیجه گیری: از آنجا که تغییرات در اگزون های 19 و 22 باعث تغییر اسید آمینه ای در میوزین بتا می شود، جهش‌های ژن MYH7 در این اگزون ها، احتمالاً سهم به سزایی در بیماران HCM این استان دارند. به هر صورت، لازم است برای نتیجه گیری بهتر، بیماران بیشتری مورد مطالعه قرار گیرند

Effect of health on economic growth: A panel data study of developed and developing countries

In this paper, we investigate the effect of health, such as fertility rate, total (birth per woman), life expectancy at birth, total (years) and mortality rate, under-5(per 1000 live birth), as well as capital stock on the economic growth of 16 developed countries and 14 developing countries using Panel Unit Root and Panel Data Model for the period 1990-2010. In this investigation we have found that capital stock and life expectancy have a statistically significant positive effect on economic growth in both groups of countries. Mortality rate has a statistically significant negative effect on economic growth in both groups of countries. On the other hand fertility rate has a statistically significant positive effect on economic growth in developed countries while it has a statistically significant negative effect on economic growth in developing countries. Also the study results show that the fixed effects approach is more appropriate

Effect of health on economic growth: A panel data study of developed and developing countries

In this paper, we investigate the effect of health, such as fertility rate, total (birth per woman), life expectancy at birth, total (years) and mortality rate, under-5(per 1000 live birth), as well as capital stock on the economic growth of 16 developed countries and 14 developing countries using Panel Unit Root and Panel Data Model for the period 1990-2010. In this investigation we have found that capital stock and life expectancy have a statistically significant positive effect on economic growth in both groups of countries. Mortality rate has a statistically significant negative effect on economic growth in both groups of countries. On the other hand fertility rate has a statistically significant positive effect on economic growth in developed countries while it has a statistically significant negative effect on economic growth in developing countries. Also the study results show that the fixed effects approach is more appropriate

Effect of health on economic growth: A panel data study of developed and developing countries

In this paper, we investigate the effect of health, such as fertility rate, total (birth per woman), life expectancy at birth, total (years) and mortality rate, under-5(per 1000 live birth), as well as capital stock on the economic growth of 16 developed countries and 14 developing countries using Panel Unit Root and Panel Data Model for the period 1990-2010. In this investigation we have found that capital stock and life expectancy have a statistically significant positive effect on economic growth in both groups of countries. Mortality rate has a statistically significant negative effect on economic growth in both groups of countries. On the other hand fertility rate has a statistically significant positive effect on economic growth in developed countries while it has a statistically significant negative effect on economic growth in developing countries. Also the study results show that the fixed effects approach is more appropriate

Study of three common mitochondrial mutations in Arab patients with nonsyndromic hearing loss in Khuzestan province, I.R.Iran

زمینه و هدف : ناشنوایی یکی از شایع ترین اختلالات حسی –عصبی است که در هر 1000 تولد زنده رخ می دهد. بیشتر ناشنوایی ها منشا ژنتیکی داشته و حدود 2-0 موارد ناشنوایی مربوط به جهش در ژن های میتوکندریایی است. این مطالعه با هدف بررسی فراوانی سه جهش میتوکندریایی A1555G ، A3243G و A7445G در ناشنوایان غیر سندرمیک استان خوزستان انجام شده است. روش بررسی: در این مطالعه توصیفی 62 دانش آموز ناشنوای غیر سندرومیک با الگوی اتوزومی مغلوب عرب استان خوزستان به روش آسان انتخاب شدند. DNA با روش استاندارد فنل کلروفرم استخراج و جهش های احتمالی در سه ژن میتوکندریایی شامل A1555G ، G3243A و A7445G با روش چند شکلی طول قطعه محدود ( PCR-RFLP ) غربالگری شد. در نهایت جهش های احتمالی به روش توالی یابی مستقیم مورد بررسی و تائید قرار گرفتند. یافته ها: در این مطالعه هیچ یک از جهش های A1555G ، A3243G و A7445G یافت نشد، با این حال دو جهش G3316A و A7445C در دو بیمار مورد مطالعه یافت شد. نتیجه گیری: این مطالعه نشان می دهد که جهش های میتوکندریایی G3316A و A7445C مسئول تعداد کمی از ناشنوایی های قبل از زبان باز کردن در جمعیت استان خوزستان می باشند و جهش های A1555G ، A3243G و A7445G در ایجاد ناشنوایی در این جمعیت نقشی نداشته اند. مطالعه ی حاضر خواهد توانست مشاوران ژنتیک در استان خوزستان را در برنامه مشاوره ژنتیک ناشنوایی خانواده ی بیماران ناشنوا یاری کند

Molecular Characterization of Paederus Spp (Coleoptera: Staphylinidae, Paederinae) the Agent of Human Linear Dermatitis in the Caspian Sea Coast, North of Iran

Background: A combined morphological and molecular survey was performed to determine the agent of human linear dermatitis Paederus Fabricius, 1775 (Coleoptera: Staphylinidae, Paederinae) species composition in Mazandaran Prov­ince in the Caspian Sea coast in northern Iran, where most of linear dermatitis cases of the country occurred. Methods: Altogether, 397 Paederus specimens were collected from May to August 2021 and classified using morphological characters and ITS2-rDNA sequence analysis. Results: Morphological investigation revealed that all the specimens were Paederus fuscipes. ITS2 polymerase chain reaction (PCR) direct-sequences and the profiles of restriction fragment length polymorphism (RFLP) derived from digestion of PCR products by HinfI, HpaII, and SalI enzymes were identical confirming the morphological results, implying that all specimens belonged to a single taxon. Conclusion: Paederus fuscipes (Fabricius, 1775) is considered the dominant taxon and responsible for linear dermatitis in Ma­zandaran Province. To our knowledge, we have provided the first molecular typing of Paederus beetles at the species level, suggesting that ITS2-rDNA characterization is an alternative tool for species discrimination of Paederus spp

Levels of Blood Biomarkers among Patients with Myocardial Infarction in Comparison to Control Group

BACKGROUND: Myocardial infarction (MI) as a term for a heart attack happens due to reduced blood flow to heart myocardium and lack of oxygen supply caused by plaques inthe interior walls of coronary arteries. With respect to the importance of MI etiology, we aimed to study the relationship of MI and blood examination variables.METHODS: This study was conducted in Mazandaran Heart Center as a hospital-based case-control Comprising 894 participants including 465 cases and 429 controls, individually matched by sex and age. Considered blood markers were analyzed using routine laboratory methods and equipment.RESULTS: Of all participants, 64.3% of the cases and 51.0% of the controls were males with a mean age of 61.2 (±13.8) in cases and 62.4 (±14.) in controls. We could not find any differences between cases and controls for total cholesterol (TC), low-density lipoprotein (LDL), high-density lipoprotein (HDL), and alkaline-phosphatase (ALP) (P>0.05). However, levels of creatine-kinase-muscle/brain (CK-MB) (P<0.0001), fasting-blood-sugar (FBS) (P<0.0001), aspartateaminotransferase (AST) (P<0.0001), alanine-transferase (ALT) (P<0.0001) and erythrocyte sedimentation rate (ESR) (P=0.001) were significantly higher in cases compared to the controls (P<0.05). Multivariable analyses revealed that the risk of MI was associated with high levels of AST (adjusted OR=24.3, 95%CI=3.5±165.6, P=0.001) and LDL (adjusted OR=7.4, 95%CI=1.0±51.8, P=0.001).CONCLUSION: Our investigation indicated that the levels of CK-MB, FBS, AST, ALT and ESR were significantly higher in patients with MI. Besides, our findings showed that the risk of MI in cases with high levels of AST and LDL was about 24 and 7 times more than the control group respectively

Extraction and Determination of Crocin in Saffron Samples by Dispersive Liquid-Liquid Microextraction

The main component responsible for color in saffron is crocin with the chemical formula of C44H64O24. Crocin is one of several carotenoids in nature that is soluble in water. This solubility is one of the reasons for its widespread usage as a colorant in food and medicine compared to other carotenoids. The coloring strength of saffron is one of the major factors that determine the quality of the saffron stigma. It will be evaluated with measuring of crocin. Microextraction is the newest and easiest method that can be successfully applied for the preconcentration and separation of crocin in saffron samples. The advantages of this method are faster, cheaper and easier analysis by UV-Vis spectrophotometry in measurement of crocin compared to the chromatographic analysis methods. The studies showed that the type and volume of disperser and extractant solvent have a significant effect on the efficiency of crocin extraction. In this work, acetone as the disperser solvent and dichlorometane as the extractant solvent were found to be suitable combinations. Under the optimal conditions, the calibration curve was linear in the range of 0.15-0.00001 μg mL-1 and the limit of detection (LOD) was calculated based on 3 Sb/m (where, Sb and m are the standard deviation of the blank and slop ratio of the calibration curve respectively) was 0.000008 μg mL-1. The procedure was applied to saffron samples and the good recovery percent for the saffron samples was obtained

Valuing a gas-fired power plant: A comparison of ordinary linear models, regime-switching approaches, and models with stochastic volatility

Energy prices are often highly volatile with unexpected spikes. Capturing these sudden spikes may lead to more informed decision-making in energy investments, such as valuing gas-fired power plants, than ignoring them. In this paper, non-linear regime-switching models and models with mean-reverting stochastic volatility are compared with ordinary linear models. The study is performed using UK electricity and natural gas daily spot prices and suggests that with the aim of valuing a gas-fired power plant with and without operational flexibility, non-linear models with stochastic volatility, specifically for logarithms of electricity prices, provide better out-of-sample forecasts than both linear models and regime-switching models.Energy spot prices Hamilton filter Markov regime switching Stochastic volatility Variogram