On the gravitational field of static and stationary axial symmetric bodies with multi-polar structure

We give a physical interpretation to the multi-polar Erez-Rozen-Quevedo solution of the Einstein Equations in terms of bars. We find that each multi-pole correspond to the Newtonian potential of a bar with linear density proportional to a Legendre Polynomial. We use this fact to find an integral representation of the $\gamma$ function. These integral representations are used in the context of the inverse scattering method to find solutions associated to one or more rotating bodies each one with their own multi-polar structure.Comment: To be published in Classical and Quantum Gravit

Higgs mediated Double Flavor Violating top decays in Effective Theories

The possibility of detecting double flavor violating top quark transitions at future colliders is explored in a model-independent manner using the effective Lagrangian approach through the $t \to u_i\tau \mu$ ($u_i=u,c$) decays. A Yukawa sector that contemplates $SU_L(2)\times U_Y(1)$ invariants of up to dimension six is proposed and used to derive the most general flavor violating and CP violating $q_iq_jH$ and $l_il_jH$ vertices of renormalizable type. Low-energy data, on high precision measurements, and experimental limits are used to constraint the $tu_iH$ and $H\tau \mu$ vertices and then used to predict the branching ratios for the $t \to u_i\tau \mu$ decays. It is found that this branching ratios may be of the order of $10^{-4}-10^{-5}$, for a relative light Higgs boson with mass lower than $2m_W$, which could be more important than those typical values found in theories beyond the standard model for the rare top quark decays $t\to u_iV_iV_j$ ($V_i=W,Z,\gamma, g$) or $t\to u_il^+l^-$. %% LHC experiments, by using a total integrated luminosity of $\rm 3000 fb^{-1}$ of data, will be able to rule out, at 95% C.L., DFV top quark decays up to a Higgs mass of 155 GeV/$c^2$ or discover such a process up to a Higgs mass of 147 GeV/$c^2$.Comment: 24 pages, 11 figure

Pharmacological activation of FOXO3 suppresses triple-negative breast cancer in vitro and in vivo

Triple-negative breast cancer (TNBC) is the most lethal form of breast cancer. Lacking effective therapeutic options hinders treatment of TNBC. Here, we show that bepridil (BPD) and trifluoperazine (TFP), which are FDA-approved drugs for treatment of schizophrenia and angina respectively, inhibit Akt-pS473 phosphorylation and promote FOXO3 nuclear localization and activation in TNBC cells. BPD and TFP inhibit survival and proliferation in TNBC cells and suppress the growth of TNBC tumors, whereas silencing FOXO3 reduces the BPD- and TFP-mediated suppression of survival in TNBC cells. While BPD and TFP decrease the expression of oncogenic c-Myc, KLF5, and dopamine receptor DRD2 in TNBC cells, silencing FOXO3 diminishes BPD- and TFP-mediated repression of the expression of these proteins in TNBC cells. Since c-Myc, KLF5, and DRD2 have been suggested to increase cancer stem cell-like populations in various tumors, reducing these proteins in response to BPD and TFP suggests a novel FOXO3-dependent mechanism underlying BPD- and TFP-induced apoptosis in TNBC cells

Cropland Capture – A Game for Improving Global Cropland Maps

Current satellite-derived global land-cover products, which are crucial for many modelling and monitoring applications, show large disagreements when compared with each another. To help improve global land cover (in particular the cropland class), we developed a game called Cropland Capture. This is a simple cross-platform game for collecting image classifications that will be used to develop and validate global cropland maps in the future. In this paper, we describe the game design of Cropland Capture in detail, including aspects such as simplicity,efficiency in data collection and what mechanisms were implemented to ensure data quality.We also discuss the impact of incentives on attracting and sustaining players in the game

Cropland Capture: A gaming approach to improve global land cover

Ponencias, comunicaciones y pósters presentados en el 17th AGILE Conference on Geographic Information Science "Connecting a Digital Europe through Location and Place", celebrado en la Universitat Jaume I del 3 al 6 de junio de 2014.Accurate and reliable information on global cropland extent is needed for a number of applications, e g. to estimate potential yield losses in the wake of a drought or for assessing future scenarios of climate change on crop production. However, current global land cover and cropland products are not accurate enough for many of these applications. One way forward is to increase the amount of data that are used to create these maps as well as for validation purposes. One method for doing this is to involve citizens in the classification of satellite imagery as undertaken using the Geo-Wiki tool. This paper outlines Cropland Capture, which is simplified game version of Geo-Wiki in which players classify satellite imagery based on whether they can see evidence of cropland or not. On overview of the game is provided along with some initial results from the first 3 months of game play. The paper concludes with a discussion of the future steps in this research

Collider Production of TeV Scale Black Holes and Higher-Curvature Gravity

We examine how the production of TeV scale black holes at colliders is influenced by the presence of Lovelock higher-curvature terms in the action of models with large extra dimensions. Such terms are expected to arise on rather general grounds, e.g., from string theory and are often used in the literature to model modifications to the Einstein-Hilbert action arising from quantum and/or stringy corrections. While adding the invariant which is quadratic in the curvature leads to quantitative modifications in black hole properties, cubic and higher invariants are found to produce significant qualitative changes, e.g., classically stable black holes. We use these higher-order curvature terms to construct a toy model of the black hole production cross section threshold. For reasonable parameter values we demonstrate that detailed measurements of the properties of black holes at future colliders will be highly sensitive to the presence of the Lovelock higher-order curvature terms.Comment: 37 pages, 11 figures, references adde

LACO-Wiki: A land cover validation tool and a new, innovative teaching resource for remote sensing and the geosciences

The validation of land cover products is an important step in the workflow of generating a land cover map from remotely-sensed imagery. Many students of remote sensing will be given exercises on classifying a land cover map followed by the validation process. Many algorithms exist for classification, embedded within proprietary image processing software or increasingly as open source tools. However, there is little standardization for land cover validation, nor a set of open tools available for implementing this process. The LACO-Wiki tool was developed as a way of filling this gap, bringing together standardized land cover validation methods and workflows into a single portal. This includes the storage and management of land cover maps and validation data; step-by-step instructions to guide users through the validation process; sound sampling designs; an easy-to-use environment for validation sample interpretation; and the generation of accuracy reports based on the validation process. The tool was developed for a range of users including producers of land cover maps, researchers, teachers and students. The use of such a tool could be embedded within the curriculum of remote sensing courses at a university level but is simple enough for use by students aged 13-18. A beta version of the tool is available for testing at: http://www.lacowiki.net

On-site correlation in valence and core states of ferromagnetic nickel

We present a method which allows to include narrow-band correlation effects into the description of both valence and core states and we apply it to the prototypical case of nickel. The results of an ab-initio band calculation are used as input mean-field eigenstates for the calculation of self-energy corrections and spectral functions according to a three-body scattering solution of a multi-orbital Hubbard hamiltonian. The calculated quasi-particle spectra show a remarkable agreement with photoemission data in terms of band width, exchange splitting, satellite energy position of valence states, spin polarization of both the main line and the satellite of the 3p core level.Comment: 14 pages, 10 PostScript figures, RevTeX, submitted to PR