11,376 research outputs found

    Combinatorics of reductions between equivalence relations

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    We discuss combinatorial conditions for the existence of various types of reductions between equivalence relations, and in particular identify necessary and sufficient conditions for the existence of injective reductions.Comment: 7 pages, 2 figure

    Direct Detection of Giant Close-In Planets Around the Source Stars of Caustic-Crossing Microlensing Events

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    We propose a direct method to detect close-in giant planets orbiting stars in the Galactic bulge. This method uses caustic-crossing binary microlensing events discovered by survey teams monitoring the bulge to measure light from a planet orbiting the source star. When the planet crosses the caustic, it is more magnified than the source star; its light is magnified by two orders of magnitude for Jupiter size planets. If the planet is a giant close to the star, it may be bright enough to make a significant deviation in the light curve of the star. Detection of this deviation requires intensive monitoring of the microlensing light curve using a 10-meter class telescope for a few hours after the caustic. This is the only method yet proposed to directly detect close-in planets around stars outside the solar neighborhood.Comment: 4 pages, 2 figures. Submitted to ApJ Letter

    Magnification as a Tool in Weak Lensing

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    Weak lensing surveys exploit measurements of galaxy ellipticities. These measurements are subject to errors which degrade the cosmological information that can be extracted from the surveys. Here we propose a way of using the galaxy data themselves to calibrate the measurement errors. In particular, the cosmic shear field, which causes the galaxies to appear elliptical, also changes their sizes and fluxes. Information about the sizes and fluxes of the galaxies can be added to the shape information to obtain more robust information about the cosmic shear field. The net result will be tighter constraints on cosmological parameters such as those which describe dark energy.Comment: 4 pages, 2 figure

    Liver Transplantation to Provide Low-Density-Lipoprotein Receptors and Lower Plasma Cholesterol in a Child with Homozygous Familial Hypercholesterolemia

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    A six-year-old girl with severe hypercholesterolemia and atherosclerosis had two defective genes at the low-density-lipoprotein (LDL) receptor locus, as determined by biochemical studies of cultured fibroblasts. One gene, inherited from the mother, produced no LDL receptors; the other gene, inherited from the father, produced a receptor precursor that was not transported to the cell surface and was unable to bind LDL. The patient degraded intravenously administered 125I-LDL at an extremely low rate, indicating that her high plasma LDL-cholesterol level was caused by defective receptor-mediated removal of LDL from plasma. After transplantation of a liver and a heart from a normal donor, the patient's plasma LDL-cholesterol level declined by 81 per cent, from 988 to 184 mg per deciliter. The fractional catabolic rate for intravenously administered 125I-LDL, a measure of functional LDL receptors in vivo, increased by 2.5-fold. Thus, the transplanted liver, with its normal complement of LDL receptors, was able to remove LDL cholesterol from plasma at a nearly normal rate. We conclude that a genetically determined deficiency of LDL receptors can be largely reversed by liver transplantation. These data underscore the importance of hepatic LDL receptors in controlling the plasma level of LDL cholesterol in human beings. (N Engl J Med 1984; 311: 1658–64.). © 1984, Massachusetts Medical Society. All rights reserved
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