1,086 research outputs found

    The Effects of Ankle Taping and Bracing on Agility, Vertical Jump, and Power

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    Leonard, T. M., Rotay, J. S., Paulson, S., Sanders, J., Shippensburg University, Shippensburg, PA Ankle sprains are the most common injury in athletics. Ankle bracing and taping are widely used in order to prevent ankle injuries. Purpose: The primary purpose was to examine the effects of ankle taping and bracing on agility, maximum vertical jump (MVJ) height, and vertical power. The secondary purpose was to determine if there were performance differences in training status (athletic vs. non-athletic) between the conditions. Methods: Nineteen participants (Age 20.6±1.5 yr, Height 173.7±11.9 cm, Mass 77.3±18.0 kg) volunteered. Of the 19 participants, 10 (8 male, 2 female, Age 21.1±1.4 yr, Height 178.6±12.4 cm, Mass 81.52±19.7 kg) were classified as athletic and 9 (3 male, 6 female, Age 20.1±1.5 yr, Height 168.5±10.0 cm, Mass 72.6±15.8 kg) were non-athletic. Subjects completed three counter-balanced conditions (control, braced, and taped). The tests were a countermovement standing MVJ, vertical jump displacement test (VJD), and the Illinois Agility test (IA). The VJD was used to calculate power. Results: There were no significant differences between conditions for the MVJ test (M: Taped = 23.2 in; Braced = 23.3 in; Control = 23.3 in; p = .79), power from the VJD test (M: Taped = 103.8 kg∙m∙s-1; Braced = 103.0 kg∙m∙s-1; Control = 106.1 kg∙m∙s-1; p = .10) or the IA test (M: Taped = 18.1 s; Braced = 18.2 s; Control = 17.9 s; p = .43). There were statistically significant differences in training status for all measurements (p \u3c .05); however, training status did not affect performance across conditions. Conclusion: According to these results, ankle bracing or taping did not significantly impair agility or MVJ and power performance. However, these measurements were affected by the training statuses of the individuals regardless of the condition

    High Prevalence of Microvascular Complications in Adults With Type 1 Diabetes and Newly Diagnosed Celiac Disease

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    Objective: The implications of celiac disease (CD) in adult patients with type 1 diabetes are unknown, with respect to diabetes-related outcomes including glycemic control, lipids, microvascular complications, quality of life, and the effect of a gluten-free diet (GFD). We identified CD in adults with type 1 diabetes and investigated the effect of a GFD on diabetes-related complications. Research design and methods: This was a case-control study conducted at a U.K. teaching hospital. Patients with type 1 diabetes aged >16 years (n = 1,000) were assessed for CD. HbA1c, lipid profile, quality of life, retinopathy stage, nephropathy stage, and degree of neuropathy before and after 1 year on a GFD were assessed. Results: The prevalence of CD was 33 per 1,000 subjects (3.3% [95% CI 2.3–4.6]). At diagnosis of CD, adult type 1 diabetic patients had worse glycemic control (8.2 vs. 7.5%, P = 0.05), lower total cholesterol (4.1 vs. 4.9, P = 0.014), lower HDL cholesterol (1.1 vs. 1.6, P = 0.017), and a higher prevalence of retinopathy (58.3 vs. 25%, P = 0.02), nephropathy (41.6 vs. 4.2%, P = 0.009), and peripheral neuropathy (41.6 vs. 16.6%, P = 0.11). There was no difference in quality of life (P > 0.1). After 1 year on a GFD, only the lipid profile improved overall, but in adherent individuals HbA1c and markers for nephropathy improved. Conclusions: Adults with undetected CD and type 1 diabetes have worse glycemic control and a higher prevalence of retinopathy and nephropathy. Treatment with a GFD for 1 year is safe in adults with type 1 diabetes and does not have a negative impact on the quality of life. Long-term microvascular and neurologic complications are responsible for major morbidity and mortality in type 1 diabetes (1). Intensive glycemic control reduces these complications and improves quality of life (1). Even patients with good glycemic control have complications, suggesting that other factors increase the risk (2). Coexisting medical problems may be a confounding factor when managing glycemic control (2). The association between celiac disease (CD) and type 1 diabetes was recognized over 30 years ago, particularly by pediatricians. The prevalence of CD in patients with adult type 1 diabetes has been reported as 1.8–8.4% (3–6). Despite a large number of prevalence studies, other important clinical factors have not been well investigated, including glycemic control, quality of life, microvascular complications, cardiac risk factors, and bone mineral density. Investigations of the effect of CD on glycemic control have been conflicting, with some studies showing improvement (7) and some deterioration (4,8) and others showing no effect (9). The difficulty in interpreting these studies is that most involve pediatric populations and are small, retrospective, and uncontrolled, leaving this question unanswered. There have been no quality-of-life assessments before and after the diagnosis of CD to assess the impact of the diagnosis and a subsequent gluten-free diet (GFD) (3). Adapting to a GFD with the restrictions of a diabetic diet may negatively impact quality of life. Peripheral neuropathy affects up to 30% of patients with adult type 1 diabetes and is a major cause of morbidity (1). Neuropathy is associated with both type 1 diabetes and CD; therefore, patients with both conditions may have a higher prevalence (10,11). In gluten-sensitive neuropathy, the pathophysiological changes lie in the humoral immune response, and a GFD seems to be beneficial (12,13). There are no studies examining neuropathy in patients with type 1 diabetes and CD or the effect of a GFD. One study examined whether CD may contribute to autonomic neuropathy in a cohort of patients with type 1 diabetes. They found no difference in the prevalence of positive antibodies in patients with and without autonomic neuropathy (14). Two previous studies have examined the effect of CD on diabetic nephropathy but were conflicting (15,16). There are currently no studies examining the prevalence of retinopathy in individuals with both type 1 diabetes and CD. Recent data in nondiabetic CD cohorts have shown a reduced risk of ischemic heart disease, possibly attributed to lower cholesterol levels and a lower prevalence of hypertension (17). Reduced bone mineral density has been associated with both CD and type 1 diabetes, but there are little data on people with both conditions (18). The aim of our study was to identify undetected CD in adult patients with type 1 diabetes and investigate the effect on diabetes-related complications before and after a GFD

    Chandra observation of two shock fronts in the merging galaxy cluster Abell 2146

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    We present a new Chandra observation of the galaxy cluster Abell 2146 which has revealed a complex merging system with a gas structure that is remarkably similar to the Bullet cluster. The X-ray image and temperature map show a cool 2 –3 keV subcluster with a ram pressure stripped tail of gas just exiting the disrupted 6 − 7 keV primary cluster. From the sharp jump in the temperature and density of the gas, we determine that the subcluster is preceded by a bow shock with a Mach number M= 2.2 ± 0.8, corresponding to a velocity v= 2200+1000−900 km s−1 relative to the main cluster. We estimate that the subcluster passed through the primary core only 0.1 –0.3 Gyr ago. In addition, we observe a slower upstream shock propagating through the outer region of the primary cluster and calculate a Mach number M= 1.7 ± 0.3. Based on the measured shock Mach numbers M∌ 2 and the strength of the upstream shock, we argue that the mass ratio between the two merging clusters is between 3 and 4 to one. By comparing the Chandra observation with an archival Hubble Space Telescope observation, we find that a group of galaxies is located in front of the X-ray subcluster core but the brightest cluster galaxy is located immediately behind the X-ray peak

    Lower gastrointestinal symptoms are associated with worse glycemic control and quality of life in type 1 diabetes mellitus

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    Objectives Lower gastrointestinal symptoms are not well characterized in people with type 1 diabetes, and the effects on quality of life and glycemic control are unknown. This study aimed to determine the prevalence of lower gastrointestinal symptoms and the effects on glycemic control and quality of life, and to investigate for underlying causes. Research design and methods This is a prospective, cohort study in secondary care. Patients with type 1 diabetes completed a gastrointestinal symptom questionnaire and the Short Form 36 V.2 quality of life questionnaire and had their hemoglobin A1c measured. Patients with diarrhea were offered reassessment and investigation as per the national guidelines. Controls without diabetes were used to compare symptom prevalence and quality of life scores. Results 706 with type 1 diabetes (mean age 41.9 years) and 604 controls (mean age 41.9 years) were enrolled. Gastrointestinal symptoms were significantly more frequent in type 1 diabetes compared with controls, in particular constipation (OR 2.4), diarrhea (OR 2.5), alternating bowel habit (OR 2.1), abdominal pain (OR 1.4), floating stools (OR 2.7), bloating (OR 1.4) and flatulence (OR 1.3) (all p<0.05). Previous pancreatitis was more frequent in type 1 diabetes (OR 4.6), but other gastrointestinal conditions were not. Gastrointestinal symptoms were associated with poorer glycemic control (p<0.01) and worse quality of life particularly in those with diarrhea. Investigation of those with diarrhea, including those with alternating bowel habit, (n=105), identified a cause in 72.3% with subsequent change in management. Conclusions Gastrointestinal symptoms are twice as common in type 1 diabetes and associated with poorer quality of life and glycemic control. Investigation of diarrhea in people with type 1 diabetes leads to a high yield of treatable conditions and a change in management in about three-quarters

    Helium and Iron in X-ray galaxy clusters

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    I discuss the role of the sedimentation of helium in galaxy cluster cores on the observed X-ray properties and present a history of the metal accumulation in the ICM, with new calculations with respect to my previous work following the recent evidence of a bi-modal distribution of the delay time in Supernovae Type Ia.Comment: 6 pages. To appear in the Proceedings of "Heating vs. Cooling in Galaxies and Clusters of Galaxies", August 2006, Garching (Germany

    On the geometric distance between quantum states with positive partial transposition and private states

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    We prove an analytic positive lower bound for the geometric distance between entangled positive partial transpose (PPT) states of a broad class and any private state that delivers one secure key bit. Our proof holds for any Hilbert space of finite dimension. Although our result is proven for a specific class of PPT states, we show that our bound nonetheless holds for all known entangled PPT states with non-zero distillable key rates whether or not they are in our special class.Comment: 16 page

    Multipartite entangled states in coupled quantum dots and cavity-QED

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    We investigate the generation of multipartite entangled state in a system of N quantum dots embedded in a microcavity and examine the emergence of genuine multipartite entanglement by three different characterizations of entanglement. At certain times of dynamical evolution one can generate multipartite entangled coherent exciton states or multiqubit WW states by initially preparing the cavity field in a superposition of coherent states or the Fock state with one photon, respectively. Finally we study environmental effects on multipartite entanglement generation and find that the decay rate for the entanglement is proportional to the number of excitons.Comment: 9 pages, 4 figures, to appear in Phys. Rev.

    Herbivorous turtle ants obtain essential nutrients from a conserved nitrogen-recycling gut microbiome.

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    Nitrogen acquisition is a major challenge for herbivorous animals, and the repeated origins of herbivory across the ants have raised expectations that nutritional symbionts have shaped their diversification. Direct evidence for N provisioning by internally housed symbionts is rare in animals; among the ants, it has been documented for just one lineage. In this study we dissect functional contributions by bacteria from a conserved, multi-partite gut symbiosis in herbivorous Cephalotes ants through in vivo experiments, metagenomics, and in vitro assays. Gut bacteria recycle urea, and likely uric acid, using recycled N to synthesize essential amino acids that are acquired by hosts in substantial quantities. Specialized core symbionts of 17 studied Cephalotes species encode the pathways directing these activities, and several recycle N in vitro. These findings point to a highly efficient N economy, and a nutritional mutualism preserved for millions of years through the derived behaviors and gut anatomy of Cephalotes ants
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