成人看護学実習において自己効力感を高める実習指導の検討 : 実習状況別の臨地実習自己効力感の違いおよびECTBを用いた実習指導評価との関連

成人看護学実習における実習状況別の臨地実習自己効力感の違いおよび、学生による実習指導評価との関連を明らかにすることを目的とし、効果的な実習指導方法への示唆を得る。成人看護学実習を履修した看護学生３年生91名を対象とし、臨地実習自己効力感および日本語版ECTBを用いた実習指導評価の自記式質問紙調査を実施した。その結果、成人看護学実習経験回数別における臨地実習自己効力感は、「対象の理解・援助効力感」の［患者の症状や状態を観察し、症状の変化に気づくこと］のみ、成人看護学実習２回目のほうが有意に高く、その他、成人看護学実習内容や受け持ち患者数などによる有意差はみられなかった。臨地実習自己効力感と実習指導評価の相関では、臨地実習自己効力感の「対象理解・援助効力感」と「指導者との関係性維持・学習姿勢効力感」が、ECTBのすべての構成要素に正の有意な相関を示した。また、臨地実習自己効力感の「友人との関係性維持効力感はECTBの「実践的な指導」「学習意欲への刺激」に正の有意な相関を示した。本研究により、実習指導者による実践的・理論的な指導、かつ学習意欲への刺激や学生への理解がなされるような指導は、学生の対象理解や看護援助への自信となり、指導者との関係性の構築や学習へ向かう姿勢を高め、自己効力感が向上することが示唆された

Size dependent lattice constant change of thiol self-assembled monolayer modified Au nanoclusters studied by grazing incidence x-ray diffraction

Size and lattice constant of thiol self-assembledmonolayer (SAM)-modified gold nanoclusters (GNCs) assembled on Au(111) surfaces after each electrochemical treatment were investigated using grazing incidence x-ray diffraction (GIXRD). When the potential was swept between 0 and 1.3 V (vs. Ag/AgCl), the size and lattice constant of GNCs slightly decreased due to the oxidative desorption of the SAMs. As the number of potential cycles increased, the size of GNCs started to increase due to the aggregation, while the lattice constant continued to decrease due to further desorption of the SAMs from the GNCs. After most of the SAMs were removed from the GNCs, the size and lattice constant monotonically increasedwith the number of potential cycles. The size dependent lattice constant change was observed when GNCs were smaller than similar to 35 angstrom

Amiodarone-induced reversible and irreversible hepatotoxicity: two case reports

Abstract Background Amiodarone is a highly effective treatment for supraventricular and ventricular tachyarrhythmia; however, it could be associated with several serious adverse effects, including liver injury. Case presentation We report the clinical and histological features of two contrasting Japanese patients with amiodarone-induced reversible and irreversible hepatotoxicity. One patient with amiodarone-induced irreversible hepatotoxicity showed liver cirrhosis during treatment with amiodarone and died of hepatic failure; the other patient, who had reversible hepatotoxicity, showed a reversible course of liver function and imaging after discontinuation of amiodarone. Conclusions We emphasize the importance of close monitoring of liver enzymes and evaluation of liver computed tomographic imaging as well as liver biopsy during treatment with amiodarone, and discontinuation should be considered when amiodarone-induced hepatotoxicity is suspected

Correction: The 5th edition of The World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms (vol 36, pg 1720, 2022)

10.1038/s41375-023-01962-5LEUKEMIA3791944-195