487 research outputs found

    Memórias de um Economista: Schacht e a Alemanha nos Anos 1920

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    Esta dissertação versa sobre a Alemanha nos anos 1920. Inicialmente será apresentado o teatro de operações da Primeira Guerra Mundial (1914-1918), mencionando as perdas humanas e materiais e enfatizando algumas das principais batalhas que compuseram este grande conflito, como as batalhas de Marne e Somme. Após, dado o fim da primeira guerra, mostrar-se-á a nova reorganização territorial da Europa, com a desintegração de impérios e o surgimento de novos países. Em seguida, discute-se sobre as reparações de guerra, bem como os imensos obstáculos no caminho para a plena restauração da ordem econômica mundial. Adiante, são colocadas as percepções e memórias do economista alemão, Hjalmar Schacht, a respeito do período em questão. Schacht foi secretário da moeda, presidente do Reichsbank e ministro da economia no período entreguerras, e por ocupar tais posições, se auto intitulava o guardião da moeda alemã, o que exigiu dele mais que controlar a política monetária, mas também lutar intransigentemente pelo fim das reparações de guerra

    Freire and planning education: The pedagogy of hope for faculty and students.

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    This paper focuses on UK higher education (HE), but the circumstances it describes have parallels throughout the Global North. Its purpose is to offer hope to faculty and students despondent about the possibility of changing a HE system inimical to much-valued aspects of professional (including planning) education. This paper argues that a Freirean-inflected understanding of reflection can create conditions in which students and faculty have the possibilities of developing a shared, and radical, understanding of the shortcomings of current HE and identify real, if sometimes modest, opportunities for change in the short term

    Corrigendum: Effects of a 3-week inpatient multidisciplinary body weight reduction program on body composition and physical capabilities in adolescents and adults with obesity

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    A correction has been made to Funding. The correct Funding statement is: “Research funded by the Italian Ministry of Health.” The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated

    The Appetite-Suppressant and GLP-1-Stimulating Effects of Whey Proteins in Obese Subjects are Associated with Increased Circulating Levels of Specific Amino Acids

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    The satiating effect of whey proteins depends upon their unique amino acid composition because there is no difference when comparing whey proteins or a mix of amino acids mimicking the amino acid composition of whey proteins. The specific amino acids underlying the satiating effect of whey proteins have not been investigated to date. Aims and Methods. The aim of the present study was to evaluate the appetite-suppressant effect of an isocaloric drink containing whey proteins or maltodextrins on appetite (satiety/hunger measured by a visual analogue scale or VAS), anorexigenic gastrointestinal peptides (circulating levels of glucagon-like peptide 1 (GLP-1) and peptide tyrosine tyrosine (PYY)) and amino acids (circulating levels of single, total [TAA] and branched-chain amino acids [BCAA]) in a cohort of obese female subjects (n = 8; age: 18.4 \ub1 3.1 years; body mass index, BMI: 39.2 \ub1 4.6 kg/m2). Results. Each drink significantly increased satiety and decreased hunger, the effects being more evident with whey proteins than maltodextrins. Similarly, circulating levels of GLP-1, PYY and amino acids (TAA, BCAA and alanine, arginine, asparagine, citrulline, glutamine, hydroxyproline, isoleucine, histidine, leucine, lysine, methionine, ornithine, phenylalanine, proline, serine, threonine, tyrosine, and valine) were significantly higher with whey proteins than maltodextrins. In subjects administered whey proteins (but not maltodextrins), isoleucine, leucine, lysine, methionine, phenylalanine, proline, tyrosine, and valine were significantly correlated with hunger (negatively), satiety, and GLP-1 (positively). Conclusions. Eight specific amino acids (isoleucine, leucine, lysine, methionine, phenylalanine, proline, tyrosine, and valine) were implicated in the appetite-suppressant and GLP-1-stimulating effects of whey proteins, which may be mediated by their binding with nutrient-sensing receptors expressed by L cells within the gastrointestinal wall. The long-term satiating effect of whey proteins and the effectiveness of a supplementation with these amino acids (i.e., as a nutraceutical intervention) administered during body weight reduction programs need to be further investigated

    Dust survival rates in clumps passing through the Cas A reverse shock -- II. The impact of magnetic fields

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    Dust grains form in the clumpy ejecta of core-collapse supernovae where they are subject to the reverse shock, which is able to disrupt the clumps and destroy the grains. Important dust destruction processes include thermal and kinetic sputtering as well as fragmentation and grain vaporization. In the present study, we focus on the effect of magnetic fields on the destruction processes. We have performed magneto-hydrodynamical simulations using AstroBEAR to model a shock wave interacting with an ejecta clump. The dust transport and destruction fractions are computed using our post-processing code Paperboats in which the acceleration of grains due to the magnetic field and a procedure that allows partial grain vaporization have been newly implemented. For the oxygen-rich supernova remnant Cassiopeia A we found a significantly lower dust survival rate when magnetic fields are aligned perpendicular to the shock direction compared to the non-magnetic case. For a parallel field alignment, the destruction is also enhanced but at a lower level. The survival fractions depend sensitively on the gas density contrast between the clump and the ambient medium and on the grain sizes. For a low-density contrast of 100100, e.g., 55\,nm silicate grains are completely destroyed while the survival fraction of 1μ1\,\mum grains is 8686\,per cent. For a high-density contrast of 10001000, 9595\,per cent of the 55\,nm grains survive while the survival fraction of 1μ1\,\mum grains is 2626\,per cent. Alternative clump sizes or dust materials (carbon) have non-negligible effects on the survival rate but have a lower impact compared to density contrast, magnetic field strength, and grain size.Comment: Accepted by MNRAS. Author accepted manuscript. Accepted on 23/01/2023. 24 pages, 21 Figure

    Effects of a 3-Week In-Hospital Body Weight Reduction Program on Cardiovascular Risk Factors, Muscle Performance, and Fatigue : A Retrospective Study in a Population of Obese Adults with or without Metabolic Syndrome

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    Background: In clinical practice, there is the diffuse conviction that obese subjects with metabolic syndrome may be more difficult to treat. Objectives and methods: The aim of the present study was that to investigate the effectiveness of a 3-week in-hospital body weight reduction program (BWRP) in a large population of obese subjects with and without metabolic syndrome (n = 1922; 222 men and 1700 women, age range 18-83 yr). Outcomes such as body mass index (BMI), total (TOT) and HDL cholesterol, systolic and diastolic blood pressures (SBP and DBP, respectively), coronary heart disease (CHD) score, fatigue severity score (FSS), and stair climbing test (SCT) time were evaluated before and after the intervention (\u394). A sex-, BMI-, and age-related stratification of the obese population with or without metabolic syndrome was applied. Results: When compared to obese subjects without metabolic syndrome, at the basal conditions, obese subjects had a poorer cardiometabolic profile, as demonstrated by higher triglycerides, TOT-cholesterol, DBP, SBP, and CHD score, and a more compromised muscle performance (evaluated by SCT), associated with more perception of fatigue (measured by FSS). Nevertheless, obese subjects with metabolic syndrome obtained more benefits from BWRP than those without metabolic syndrome for some outcomes (i.e., \u394TOT-cholesterol, \u394SBP, and \u394CHD score). Despite these differences, the BWRP-induced weight loss was similar between the two groups (i.e., \u394BMI) as well as the gain of muscle performance (i.e., \u394SCT) and the reduction of fatigue (i.e., \u394FSS). Interestingly, the potentially deleterious fall in HDL-cholesterol levels after BWRP was less evident in obese subjects with metabolic syndrome than those without metabolic syndrome. When pooling all data, the \u394CHD score was associated with age, sex, and metabolic syndrome. The remaining outcomes, such as \u394BMI, \u394FSS, and \u394SCT time, were associated with sex and age but not with metabolic syndrome. Finally, \u394BMI was positively correlated with \u394CHD score, \u394FSS, and \u394SCT time in both obese subjects without metabolic syndrome and obese subjects with metabolic syndrome. Conclusions: When comparing obese subjects undergoing a BWRP, metabolic syndrome is not a negative predictive factor affecting the effectiveness of this intervention in terms of weight loss, muscle performance, and psychological well-being

    Cardiometabolic Index (CMI) and Visceral Adiposity Index (VAI) Highlight a Higher Risk of Metabolic Syndrome in Women with Severe Obesity

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    Recent evidence shows that simple and inexpensive anthropometric measurements can be used to identify, at an early stage, women with obesity at increased risk of developing metabolic syndrome (MetS). Thus, the aim of this study was to compare the accuracy of five different indexes of adiposity and/or body composition in identifying MetS in a group of 876 women (mean age ± SD: 52.1 ± 13.8 years; body mass index (BMI): 43.6 ± 6.1 kg m−2). The following indexes were determined for each subject: waist-to-hip ratio (WHR), waist-to-height ratio (WtHR), body mass fat index (BMFI), visceral adiposity index (VAI), and cardiometabolic index (CMI). Overall, the presence of MetS was detected in 544 patients (62%). Pearson correlation coefficients were calculated to evaluate the relationships between body composition indexes and metabolic characteristics of the women. Receiver operating characteristic (ROC) analysis was used to determine the best predictor for each adiposity index among metabolic risk factors. The ROC analysis showed VAI (AUC = 0.84) and CMI (AUC = 0.86) showed the best performance in predicting MetS. Differences were found between the ROC area of CMI and VAI with all other indexes (p 0.92 for WHR, >0.76 for WtHR, >30.1 kg m−1 for BMFI, >1.94 for VAI, and >0.84 for CMI. In addition, VAI and CMI were the most sensitive and specific indexes compared with other indexes. In conclusion, VAI and CMI represent the most useful and reliable indexes to be used for detecting MetS in women suffering from obesity in clinical practice

    Pathological gambling in adolescence: A narrative review

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    Pathological gambling is an emerging and increasing phenomenon in Western counties. This work is aimed at reviewing the existing literature on this topic, paying special attention to its development, course and outcome in adolescence. We will explore epidemiological data, the instruments for the diagnostic and clinical assessment, the course and the outcome of the disorder, the comorbidity with other psychiatric syndromes and disorders. The main risk factors will be described at individual, social and community level. We provide an overview of the available pharmacological and psychological treatments and we report a clinical vignette in order to describe the psychological and psychopathological features of pathological gambling in adolescence

    Potential role of omega-3 polyunsaturated fatty acids in pediatric food allergy

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    Polyunsaturated fatty acids (PUFAs) are involved both in immune system regulation and inflammation. In particular, within the PUFAs category, omega-3 (ω-3) may reduce inflammation, whereas omega-6 (ω-6) PUFAs are generally considered to have a proinflammatory effect. Recent evidence highlights an imbalance in the ω-3: ω-6 ratio with an increased intake of ω-6, as a consequence of the shift towards a westernized diet. In critical age groups such as infants, toddlers and young children, as well as pregnant and lactating women or fish allergic patients, ω-3 intake may be inadequate. This review aims to discuss the potential beneficial effects of PUFAs on pediatric food allergy prevention and treatment, both at prenatal and postnatal ages. Data from preclinical studies with PUFAs supplementation show encouraging effects in suppressing allergic response. Clinical studies results are still conflicting about the best timing and dosages of supplementation and which individuals are most likely to benefit; therefore, it is still not possible to draw firm conclusions. With regard to food-allergic children, it is still debated whether PUFAs could slow disease progression or not, since consistent data are lacking. In conclusion, more data on the effects of ω-3 PUFAs supplementation alone or in combination with other nutrients are warranted, both in the general and food allergic population
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