126 research outputs found
Secure Cloud using RGB value and Homomorphic Encryption for Shared Data in Cloud
Cloud computing is a promise computing technology where all the services are provided via Internet. Recent Years have seen increasing attractiveness of storing and managing personal data on the cloud. Preserving confidentiality of personal data while offering efficient functionalities thus becomes an important and pressing research issue. We all know the demand for privacy of information of enterprise has increased tremendously. For this, technologies such as data encryption methods are used. However a critical problem arises when there is a need of computation on encrypted data where privacy is established. At this situation homomorphic encryption can be applied. In this paper we propose the application that perform the operation on encrypted data and provides the same result on raw data as well as encrypted data when calculation to be performed. We also use RGB value for accountability purpose and proxy re-encryption technique for preventing chosen cipher text attacks.
DOI: 10.17762/ijritcc2321-8169.150613
Optimization of High Utility Itemset Mining from Large Transaction Databases on multi core processor
High utility itemset mining is an emerging era that extends frequent itemset mining to identify itemsets in a transaction database with utility values associated with every item above a given threshold. Researchers recently proposed algorithm TWU (Transaction Weighted Utility) has anti-monotone property for pruning the datasets, but it is an overestimate of itemset utility that leads to more search space. In this paper we present an algorithm that takes features of CTU-PROL which is proposed by Researchers. It uses TWU with pattern growth based on a compact utility pattern tree data structure. Our algorithm runs on multi-core processor when the main memory is insufficient to deal with large datasets. An experimental result shows a remarkable speedup for large datasets than the previous algorithms. It can mine large data set more efficiently of both dense and sparse data.
DOI: 10.17762/ijritcc2321-8169.150616
Urinary tract infection caused by Myroides spp. in diabetic patients: To be or not to be
Myroides is a non-fermentative, Gram-negative rod-like bacteria. It is a rare opportunistic pathogen which has been reported to cause many serious infections. Management of infections caused by Myroides can be challenging due to its high resistance to most antibiotics. We report three cases of urinary tract infection (UTI) due to Myroides species in patients with diabetes mellitus Type II. Myroides spp. isolated were resistant to all the antibiotics tested: Amoxicillin-clavulanic acid, piperacillin-tazobactam, cefepime, ceftriaxone-cefoperazone sulbactam, amikacin, gentamicin, imipenem, meropenem, ciprofloxacin, colistin, tigecycline, and co-trimoxazole. Two strains were sensitive to minocycline (minimum inhibitory concentration <1 μg/mL). Two patients had Foley’s catheter in place and one patient had urinary retention at the time of diagnosis. The infection in two cases was nosocomial, whereas one case appeared to have a community-acquired infection with Myroides. Clinicians should consider the possibility of Myroides as a pathogen in UTI in diabetic patients, especially in nosocomial settings
Safety evaluation of directly observed treatment short course (DOTS) regimen in a tertiary care hospital, Pune
Background: Directly observed treatment short course (DOTS) is a cornerstone of Revised National Tuberculosis Control Program of India. Adverse drug reactions (ADRs) induced by this therapy is common and it causes significant morbidity and mortality. Hence, the present study was undertaken to determine the incidence and pattern of ADRs and to assess causality and severity.Methods: We conducted prospective, observational study at DOTS center of tertiary care hospital, Pune. 150 pulmonary tuberculosis patients undergoing DOTS therapy were enrolled. They were monitored weekly in an intensive phase and monthly in the continuation phase. The suspected ADRs were recorded and assessed for causality and severity by standard algorithms.Results: Incidence of ADRs due to DOTS was 19.33% & total 35 ADRs had occurred in our study. Gastrointestinal intolerance, arthralgia & itching with or without rashes were most common ADRs (incidence rates: 12.67%, 2.67% and 2.67%, respectively). On evaluation of causality by Naranjo algorithm, majority of ADRs 91.43% were “possible.” As per WHO- Uppsala Monitoring Center scale, majority of ADRs 91.43% were “possible.” As per Modified Hartwig and Siegel scale, majority of ADRs were “moderate” (48.57%) but 8.57% were “severe.” Female gender was found to be a significant risk factor for developing ADRs (odds ratio: 3.08, 95% confidence interval: 1.33-7.12. 3.33%). ADRs & hepatotoxicity was major reason for defaulting from DOTS (60%).Conclusion: ADRs induced by DOTS are common and there is need of incorporating pharmacovigilance system for this vital public health program. Counseling of patients for timely prevention, detection, and management of ADRs will help in minimizing the further occurrence of ADRs
Effectiveness of low dose physostigmine for dose reduction of morphine in pain management
Background: This is an interventional study, undertaken in the experimental animal models for the evaluation of the antinociceptive potential of Physostigmine and its combination with Morphine at their sub-analgesic doses. The objective of the study was to evaluate the antinociceptive potential of Physostigmine alone and in combination with morphine.Methods: Antinociceptive effect of Physostigmine in three graded doses (50, 100 and 200 μg/kg) and combination of Physostigmine at low dose (50 μg/kg) with sub-analgesic dose of Morphine (0.1 mg/kg) and Morphine in analgesic dose (1 mg/kg) was evaluated by using Hot Water Bath method in albino rats.Results: Comparison of maximal possible effect in percentage (MPE in %) between groups at 90 minutes in control, Morphine, Physostigmine in 50, 100, 200 μg/ kg doses and combination group respectively, demonstrated significant difference (p <0.001) when compared by one way ANOVA test. There was no much increase in maximal possible effect in the tail withdrawal latency in Physostigmine 50 μg/kg (SC) treatment at 90 min (5.50±0.88) in comparison to control (NS) treatment group. Combination treatment of low doses of both Physostigmine 50 μg/kg + Morphine 0.1 mg/kg increased in maximal possible effect the tail withdrawal latency 90 min (53.87±1.38) in-comparison to control (NS) treatment group (6.17±0.92).Conclusions: Physostigmine is more potent antinociceptive than Morphine and Physostigmine potentiated the antinociceptive activity of low dose of standard drug Morphine
Papilliferous Keratoameloblastoma: Systematic review
Papilliferous keratoameloblastoma (PKA) is a rare entity, and not much is known about its clinicodemographic features or biological nature. This review aimed to provide clarity regarding the characterisation of the demographic, clinical, radiological and histopathological features of PKA. Case reports of PKA were identified through a systematic search across multiple databases. The search yielded a total of 10 cases, half of which were of Indian origin. All the cases invariably occurred in the mandibular posterior region and involved the right side; only one case primarily involved the left side of the mandible. PKA should be considered a variant of the conventional ameloblastoma that is towards the more aggressive end of the spectrum. It tends to occur in older individuals (in their fifth decade or older), with a marked propensity to occur in the right mandibular posterior region. Surgical resection with diligent follow-up is warranted in the treatment of PKA.
Keywords: Odontogenic Tumors; Ameloblastoma; Keratin; Odontogenic Keratocyst
Temporal Trends and Outcomes of Acute Myocardial Infarction in Patients With Cancer
Background: Data on outcomes of ST-elevation myocardial infarction (STEMI) in patients with cancer are scarce. We investigated the nationwide trends in admissions for STEMI, utilization of percutaneous coronary intervention (PCI), and in-hospital outcomes in patients with the three most common cancer diagnoses (lung, breast, and colon) compared to patients without cancer. Methods: We conducted an administrative database study using the Nationwide Inpatient Sample (NIS). All in-patient hospitalizations for STEMI from 2001 to 2011 were identified. Patients with concomitant diagnosis of lung, breast or colon cancer were identified using appropriate International classification of diagnosis (ICD 9-CM) codes. Primary outcome was utilization of PCI and in-hospital mortality in patients with cancer compared to those without cancer. Results: Utilization of PCI was 30.8% (1,191/3,871), 20.2% (4,541/22,480) and 17.3% (1,716/9,944) in patients with breast, lung and colon cancer, respectively. Among patients without any of these cancers, use of PCI was 49.6%. In-hospital mortality was highest in patients with lung cancer (57.1%) and lowest in patients without cancer (25.7%). Conclusions: Patients with cancer have significantly worse in-hospital mortality compared to those without cancer, partly due to a relatively lower rate of PCI utilization in cancer patients with STEMI
Wireless Charging: Its types, Standards and Applications
An electrical gadget can be powered without cords by providing electrical via an air pocket to the device in order to re-charge its capacity. The performance and practicality of cordless charging tech have noticeably enhanced lately. The introduction to cordless charging in this paper covers its basics. The evaluation of standards, which includes Qi and the A4WP, is then given, as well as a focus on their communications channels. Next, we put out a cutting-edge idea for cordless charger networking, which enables chargers to be linked for easier data gathering and management. We explain how the wireless charger network can be used to assign users to chargers, which demonstrates the usefulness in terms of a reduction costs for users to find the best chargers to recharge their mobile devices
Dissociable contributions of mediodorsal and anterior thalamic nuclei in visual attentional performance: a comparison using nicotinic and muscarinic cholinergic receptor antagonists
Background:
Thalamic subregions mediate various cognitive functions, including attention, inhibitory response control and decision making. Such neuronal activity is modulated by cholinergic thalamic afferents and deterioration of such modulatory signaling has been theorised to contribute to cognitive decline in neurodegenerative disorders. However, the thalamic subnuclei and cholinergic receptors involved in cognitive functioning remain largely unknown.
Aims:
We investigated whether muscarinic or nicotinic receptors in the mediodorsal thalamus and anterior thalamus contribute to rats’ performance in the five-choice serial reaction time task, which measures sustained visual attention and impulsive action.
Methods:
Male Long-Evans rats were trained in the five-choice serial reaction time task then surgically implanted with guide cannulae targeting either the mediodorsal thalamus or anterior thalamus. Reversible inactivation of either the mediodorsal thalamus or anterior thalamus were achieved with infusions of the γ-aminobutyric acid-ergic agonists muscimol and baclofen prior to behavioural assessment. To investigate cholinergic mechanisms, we also assessed the behavioural effects of locally administered nicotinic (mecamylamine) and muscarinic (scopolamine) receptor antagonists.
Results:
Reversible inactivation of the mediodorsal thalamus severely impaired discriminative accuracy and response speed and increased omissions. Inactivation of the anterior thalamus produced less profound effects, with impaired accuracy at the highest dose. In contrast, blocking cholinergic transmission in these regions did not significantly affect five-choice serial reaction time task performance.
Conclusions/interpretations:
These findings show the mediodorsal thalamus plays a key role in visuospatial attentional performance that is independent of local cholinergic neurotransmission
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