Teknologi Smartphone Android dan Aplikasinya sebagai Pengendali Pintu Air Daerah Aliran Sungai (DAS)

Pengoperasian pintu air pada aliran sungai saat ini masih menggunakan sistem manual dengan menggunakan campur tangan tenaga manusia untuk pengendali buka tutupnya. Hal ini mendorong peneliti untuk melakukan penelitian dengan sistem kendali berbasis smartphone berbasis android. Dalam penelitian ini penulis menggunakan smartphone android sebagai sarana untuk kendali pintu air. Smartphone dipilih oleh penulis karena saat ini menjadi alat komunikasi sehari-hari yang mobile di semua kalangan masyarakat sedangkan andriod merupakan sistem operasi yang sebagian besar dipakai pada smartphone tersebut. Smartphone berbasis android akan secara langsung mengendalikan buka tutup pintu Daerah Aliran Sungai (DAS) dengan menggunakan program aplikasi. Masukan dari aplikasi akan memberikan informasi perintah yang diberikan, selanjutnya akan diterima oleh sistem kendali yang terhubung pada mekanisme gerakan mekanik pintu air sungai. Peralatan kendali menggunakan perangkat Arduino Uno yang mampu mengubah signal digital menjadi gerakan mekanik dalam mengoperasikan pintu DAS. Hasil penelitian yang diperoleh, penggunaan perangkat kendali Arduino Uno tidak menyediakan ruang dalam pengelolaan database secara online, maka dibutuhkan software pendukung lainnya untuk mengatasi hal tersebut. Sebagai pengendali dan sistem android merupakan media penghubung informasi saling terkait merupakan sumber informasi yang terbuka

MAT-736: DEVELOPMENT OF HIGH STRENGTH NANO-SILICA MODIFIED RUBBERCRETE

Several research works have been carried out to study properties of concrete containing crumb rubber (rubbercrete) as a partial replacement to fine aggregate. Rubbercrete exhibits numerous benefits compared to conventional concrete such as lower in density, increased ductility, enhanced plastic capacity, higher toughness, higher impact resistance, better chloride penetration, lower thermal conductivity, higher noise reduction factor and better electrical resistivity. It has also been known to have better energy dissipation, durability and damping ratio. However, the main drawbacks of rubbercrete are decreasing in strengths and Young\u27s modulus. Therefore, to improve strengths of the rubbercrete, the crumb rubber has been pre-coated with nano-silica. Results have revealed that nano-silica modified rubbercrete can be produced with high strengths due to the densification of the interfacial transition zone (ITZ) and refining pore system of the rubbercrete

Utilization Pattern of Vancomycin in a University Teaching Hospital in Oman: Comparison with International Guidelines

Purpose: To assess the prescribing and utilization pattern of vancomycin in Sultan Qaboos University Hospital (SQUH) in Oman.Methods: A retrospective study that included in-patients at SQUH who had used vancomycin from January 1 2009 to December 31 2009 was conducted to determine the utilization patterns of the drug vis a vis to the Hospital Infection Control Practices Advisory Committee (HICPAC) guidelines and the North American Therapeutic Drug Monitoring Consensus (NATDMC) recommendations. Information regarding patient characteristics and vancomycin therapy were obtained from patients’ medical records.Statistical analyses were performed using descriptive statistics.Results: Out of 478 prescriptions for 365 patients, 79.1 % were considered inappropriate, based on HICPAC guidelines. This was mainly due to the continuous use of vancomycin following negative microbiological cultures for â-lactam-resistant Gram-positive microorganisms. Vancomycin wasprescribed mostly for treatment of sepsis (27.1 %), followed by prophylaxis against various clinical conditions (20.8 %). Therapeutic drug monitoring (TDM) practices at SQUH did not comply with NATDMC recommendations on the use of trough concentration in the specified range as a guide for monitoring of therapy.Conclusion: Irrational use of vancomycin was recorded in this study. The need for a restrictive policy and a revision of the current TDM in the setting are recommended..Keywords: Vancomycin, Drug utilization, Therapeutic drug monitoring, Infectio

Inverse model based adaptive control of magnetic levitation system

This paper presents, an adaptive finite impulse response (FIR) filter based controller used for the tracking of a ferric ball under the influence of magnetic force. The adaptive filter is designed online as approximate inverse system. To stabilize the open-loop unstable and highly nonlinear magnetic levitation system, PID controller is designed using polynomial approach. To improve the stability, an adaptive FIR filter is added along side the PID controller while the use of the proposed controller has improved tracking. Since adaptive FIR filters are inherently stable so the controller remains stable. Experimental results are included to highlight the excellent position tracking performance

Binding of IFT22 to the intraflagellar transport complex is essential for flagellum assembly

Intraflagellar transport (IFT) relies on motor proteins and the IFT complex to construct cilia and flagella. The IFT complex subunit IFT22/RabL5 has sequence similarity with small GTPases although the nucleotide specificity is unclear because of non-conserved G4/G5 motifs. We show that IFT22 specifically associates with G-nucleotides and present crystal structures of IFT22 in complex with GDP, GTP, and with IFT74/81. Our structural analysis unravels an unusual GTP/GDP-binding mode of IFT22 bypassing the classical G4 motif. The GTPase switch regions of IFT22 become ordered upon complex formation with IFT74/81 and mediate most of the IFT22-74/81 interactions. Structure-based mutagenesis reveals that association of IFT22 with the IFT complex is essential for flagellum construction in Trypanosoma brucei although IFT22 GTP-loading is not strictly required

SYNTHESIS, STRUCTURAL ELUCIDATION AND ANTIMICROBIAL EVALUATION OF 2-{4-(T-AMINO)-2-(BUT-2-YN-1-YL)}-1, 3 BENZOTHIAZOLE DERIVATIVES

Objective: A new series of 2-{4-(t-amino)-2-(but-2-yn-1-yl)}-1,3-benzothiazole derivatives, 2-[4-(pyrrolidin-1-yl)but-2-yn-1-yl]-1,3-benzothiazole (BZ2), 2-[4-(2-methylpiperidin-1-yl)but-2-yn-1-yl]-1,3-benzothiazole (BZ3), 2-[4-(piperidin-1-yl) but-2-yn-1-yl]-1,3-benzothiazole (BZ4), 2-[4-(azepan-1-yl)but-2-yn-1-yl]-1,3-benzothiazole (BZ5), 2-[4-(4-methylpiperazin-1-yl) but-2-yn-1-yl]-1,3-benzothiazole (BZ6), 2-[4-(2, 6-dimethylpiperidin-1-yl) but-2-yn-1-yl]-1, 3-benzothiazole (BZ7) were synthesized and screened in vitro as potential antimicrobial agents.Methods: In-vitro antimicrobial activity evaluation was done, by agar diffusion method and broth dilution test against Staphylococcus aureus ATCC 6538p, Candida albicans ATCC 10231, Pseudomonas aeruginosa ATCC 9027, Escherichia coli ATCC 8739, and Bacillus subtilis ATCC 6633. Minimum inhibitory concentration (MIC) and Minimum bactericidal concentration (MBC) were determined. The results of antimicrobial testing were compared to two positive control drugs ciprofloxacin (5 µg/ml) and fluconazole (500µg/ml).Results: Compound 2-[4-(azepan-1-yl) but-2-yn-1-yl]-1,3-benzothiazole (BZ5) showed the highest antibacterial activity against S. aureus with MIC value of 15.62 µg/ml while; Compound 2-[4-(2,6-dimethylpiperidin-1-yl)but-2-yn-1-yl]-1,3-benzothiazole (BZ7) exhibited the highest antibacterial activity against P. aeruginosa with MIC value of 31.25 µg/ml. Compounds 2-[4-(pyrrolidin-1-yl)but-2-yn-1-yl]-1,3-benzothiazole (BZ2) and 2-[4-(azepan-1-yl)but-2-yn-1-yl]-1,3-benzothiazole (BZ5) showed the highest antifungal activity against C. albicans with MIC value of 15.62 µg/ml (for both).Conclusion: The results obtained showed variation in the antibacterial and antifungal activity based on the structure of the cyclic amines in these amino acetylenic benzothiazole derivatives. Keywords: Benzothiazole, Aminoacetylenic, Antibacterial, Antifungal, Mannich reactio