Power of Municipal Corporations to Lay Off Employees, Atwood v. Judge

At a time when the future of the American economy appears bleak, and the necessity to curtail vital urban services becomes commonplace in our cities, the significance of the decision rendered by the Ohio Court of Appeals for Columbiana County in Atwood v. Judge\u27 deserves to be noted. The tension between the public interest in maintaining vital services within the community and the state mandate\u27 that a city operate within its budget is not satisfactorily resolved by the court

C∗C^*-algebras generated by truncated Toeplitz operators

We obtain an analogue of Coburn's description of the Toeplitz algebra in the setting of truncated Toeplitz operators. As a byproduct, we provide several examples of complex symmetric operators which are not unitarily equivalent to truncated Toeplitz operators having continuous symbols.Comment: 12 page

Spatial isomorphisms of algebras of truncated Toeplitz operators

We examine when two maximal abelian algebras in the truncated Toeplitz operators are spatially isomorphic. This builds upon recent work of N. Sedlock, who obtained a complete description of the maximal algebras of truncated Toeplitz operators.Comment: 24 page

Common Cyclic Vectors for Normal Operators

If μis a finite compactly supported measure on C, then the set Sμ of multiplication operators Mᵩ : L2 (μ) --\u3e L2 (μ), Mᵩ f = ᵩ f, where ᵩ ϵ L ∞ (μ) is injective on a set of full μ measure, is the complete set of cyclic multiplication operators on L2 (μ) In this paper, we explore the question as to whether or not Sμ has a common cyclic vecto

Common Cyclic Vectors for Unitary Operators

In this paper, we determine whether or not certain natural classes of unitary multiplication operators on L2(dƟ) have common cyclic vectors. For some classes which have common cyclic vectors, we obtain a classification of these vectors

Truncated Toeplitz Operators on Finite Dimensional Spaces

In this paper, we study the matrix representations of compressions of Toeplitz operators to the finite dimensional model spaces H2ƟBH2, where B is a finite Blaschke product. In particular, we determine necessary and sufficient conditions - in terms of the matrix representation - of when a linear transformation on H2ƟBH2 is the compression of a Toeplitz operator. This result complements a related result of Sarason [6]

Creditor\u27s Rights in Ohio: An Extensive Revision

House Bill No. 254, effective August 26, 1982, involves a balancing of competing interests as well as an attempt to bring Ohio law into compliance with the procedural requirements mandated, on Constitutional grounds, by various U.S. Supreme Court cases. It involves a cost-benefit analysis because, in making decisions in this area, one must balance the costs associated with procedural requirements against the benefits afforded to consumers. The costs involved are costs to consumers, as there is little doubt that any costs associated with the procedural requirements in effect since August 26, 1982, will be borne by consumers. To be sure, financial institutions are subject to financial and regulatory constraints. However, given any reasonable assumptions about elasticity of demand, the financial institutions have the economic power to pass increased costs on. Of course, we are talking about primary demand, not selective demand; selective demand is not an issue since all financial institutions will be subject to procedural requirement of H.B. 254. As for regulation, this author is not aware of any regulations that would prevent financial institutions from passing the procedural cost on to consumers

Can Reproductive Health Voucher Programs Improve Quality of Postnatal Care? A Quasi-Experimental Evaluation of Kenya’s Safe Motherhood Voucher Scheme

This study tests the group-level causal relationship between the expansion of Kenya’s Safe Motherhood voucher program and changes in quality of postnatal care (PNC) provided at voucher-contracted facilities. We compare facilities accredited since program inception in 2006 (phase I) and facilities accredited since 2010-2011 (phase II) relative to comparable non-voucher facilities. PNC quality is assessed using observed clinical content processes, as well as client-reported outcome measures. Two-tailed unpaired t-tests are used to identify differences in mean process quality scores and client-reported outcome measures, comparing changes between intervention and comparison groups at the 2010 and 2012 data collection periods. Difference-in-differences analysis is used to estimate the reproductive health (RH) voucher program’s causal effect on quality of care by exploiting group-level differences between voucher-accredited and non-accredited facilities in 2010 and 2012. Participation in the voucher scheme since 2006 significantly improves overall quality of postnatal care by 39% (p=0.02), where quality is defined as the observable processes or components of service provision that occur during a PNC consultation. Program participation since phase I is estimated to improve the quality of observed maternal postnatal care by 86% (p=0.02), with the largest quality improvements in counselling on family planning methods (IRR 5.0; p=0.01) and return to fertility (IRR 2.6; p=0.01). Despite improvements in maternal aspects of PNC, we find a high proportion of mothers who seek PNC are not being checked by any provider after delivery. Additional strategies will be necessary to standardize provision of packaged postnatal interventions to both mother and new-born. This study addresses an important gap in the existing RH literature by using a strong evaluation design to assess RH voucher program effectiveness on quality improvement

Combinatorial approaches for mitigating resistance to KRAS-targeted therapies.

Approximately 15% of all cancer patients harbor mutated KRAS. Direct inhibitors of KRAS have now been generated and are beginning to make progress through clinical trials. These include a suite of inhibitors targeting the KRASG12C mutation commonly found in lung cancer. We investigated emergent resistance to representative examples of different classes of Ras targeted therapies. They all exhibited rapid reactivation of Ras signaling within days of exposure and adaptive responses continued to change over long-term treatment schedules. Whilst the gene signatures were distinct for each inhibitor, they commonly involved upregulation of upstream nodes promoting mutant and wild type Ras activation. Experiments to reverse resistance unfortunately revealed frequent desensitization to members of a panel of anti-cancer therapeutics, suggesting that salvage approaches are unlikely to be feasible. Instead, we identified triple inhibitor combinations that resulted in more durable responses to KRAS inhibitors and that may benefit from further pre-clinical evaluation