552 research outputs found

    Applying the Student-Athlete Success Wheel: Examining the Academic and Social Experiences of Intercollegiate Student-Athletes

    Get PDF
    The present study investigated how different elements of the Student-Athlete Success Wheel play a role in helping intercollegiate athletes at a Midwestern Division I university to be successful in both their roles: student and athlete. Student-athlete participants (n=63) were asked to rate the influence of the 10 ‘spokes’ of the Student-Athlete Success Wheel on their daily lives. Additionally, respondents provided qualitative feedback about the most beneficial aspect of the Student-Athlete Success Wheel and made suggestions on how to improve the student-athlete experience. After analyzing the data, the results indicated that the three elements most valuable to student-athletes were motivation, relationship building, and mentors. Potential reasons justifying the three most valuable ‘spokes’ were provided, as well as recommendations for how to improve areas that were not rated as highly. Because this is the first academic study that applies the Student-Athlete Success Wheel, more research is needed to confirm the results of this study.https://openprairie.sdstate.edu/honors_isp/1016/thumbnail.jp

    Hepatitis C Testing and Treatment Access Among People Who Inject Drugs

    Get PDF
    Hepatitis C (HCV) remains a global issue as it affects 2-3% of the world’s population. Despite Canada’s universal access to healthcare, barriers to accessing testing and treatment for HCV has contributed to approximately 250,000 Canadians living with chronic HCV. People who inject drugs (PWID) account for about 60% of all HCV cases in Canada, making them the primary target for public health interventions, namely prevention and harm reduction. Harm reduction efforts have proven effective to reduce the incidence of infectious diseases and to prevent overdoses, but there remains a large proportion of individuals living with the virus who are unaware of their status and who require treatment. Current HCV discourse lacks a local understanding of barriers and facilitators in the Canadian context. This study explored the experience of accessing HCV testing and treatment among PWID, identifying barriers and facilitators to HCV care throughout the individual’s journey from diagnosis to cure within four domains of access: acceptability, availability, affordability, and geographic accessibility. The role of the client-provider relationship and the impact of harm reduction was also considered as it hinders or facilitates the accessibility of HCV testing and treatment. Qualitative interviews were conducted with clients (self-identified current or former intravenous substance user) and health providers in the Waterloo and Peel Regions of Ontario. Stigma and misinformation of HCV and substance use were regarded as systemic forces that perpetuate oppression, reflected throughout all access domains on a community and individual level. Facilitators and solutions identified in this study indicate a need to apply community health models and resources, more widely adopt harm reduction and patient- centred approaches to clinical care, and further consider or utilize intersectoral action to ensure equitable access to health services

    Planetree Model BLOOMS Success

    Get PDF
    https://digitalcommons.misericordia.edu/research_posters2020/1039/thumbnail.jp

    Evidence Based Practice Project: Families Struggling with Sexual Abuse and/ or Incest

    Get PDF
    Structural family therapy was examined for effectiveness when working with family populations that struggle with incest and / or sexual abuse. This evidence based project reviewed and studied research to effectively create curriculum. The primary goal of structural family therapy is to assist families in mapping the family structure through boundary making, hierarchies, and subsystems to help clients resolve individual mental health symptoms and relational problems, interventions include stabilization, psychoeducation, coping mechanisms, creating boundaries, expressing emotions, and restructuring roles. Enactments and symbolic representation was found to be beneficial when progressing to goals in a therapy setting

    Differential Responses of Targeted Lung Redox Enzymes to Rat Exposure to 60 or 85% Oxygen

    Get PDF
    Rat exposure to 60% O2 (hyper-60) or 85% O2 (hyper-85) for 7 days confers susceptibility or tolerance, respectively, of the otherwise lethal effects of exposure to 100% O2. The objective of this study was to determine whether activities of the antioxidant cytosolic enzyme NAD(P)H:quinone oxidoreductase 1 (NQO1) and mitochondrial complex III are differentially altered in hyper-60 and hyper-85 lungs. Duroquinone (DQ), an NQO1 substrate, or its hydroquinone (DQH2), a complex III substrate, was infused into the arterial inflow of isolated, perfused lungs, and the venous efflux rates of DQH2 and DQ were measured. Based on inhibitor effects and kinetic modeling, capacities of NQO1-mediated DQ reduction (Vmax1) and complex III-mediated DQH2 oxidation (Vmax2) increased by ∼140 and ∼180% in hyper-85 lungs, respectively, compared with rates in lungs of rats exposed to room air (normoxic). In hyper-60 lungs, Vmax1 increased by ∼80%, with no effect on Vmax2. Additional studies revealed that mitochondrial complex I activity in hyper-60 and hyper-85 lung tissue homogenates was ∼50% lower than in normoxic lung homogenates, whereas mitochondrial complex IV activity was ∼90% higher in only hyper-85 lung tissue homogenates. Thus NQO1 activity increased in both hyper-60 and hyper-85 lungs, whereas complex III activity increased in hyper-85 lungs only. This increase, along with the increase in complex IV activity, may counter the effects the depression in complex I activity might have on tissue mitochondrial function and/or reactive oxygen species production and may be important to the tolerance of 100% O2 observed in hyper-85 rats

    The D.C. disc armature traction motor: research into the design and performance of d.c. axial-field machines for use in battery electric traction

    Get PDF
    With growing interest in battery electric vehicles, the use of the disc armature motor, with its inherent high efficiency and power density, is investigated for such applications. With the need to establish an optimum design for a given specification a computer-aided design procedure is developed with due regard to the motor operating principles and the performance of existing prototypes. This procedure presents a large number of alternative designs to meet a specification in terms of the voltage , power and speed requirement. The magnet material to be used is the only other necessary input to the program, although various restrictions may be applied if desired. With the use of a duplex wave winding sometimes called for, and in certain cases alternative methods of connection available, a study is made of a particular winding in terms of the e.m.f.s generated in the primary armature paths and those short-circuited by the brushes. It is shown that an optimum arrangement exists and if this is not specified,significant deterioration in motor performance results as verified experimentally. The thermal performance of the motor is discussed and appropriate rating conditions are proposed as an aid to future design. Finally the use of the motor in a practical application is studied with the aid of a simulation model of an electric vehicle and practical road testing. It is shown that improvements in overall vehicle performance result when a disc armature motor is specified in place of a comparable series wound machine

    In vivo Detection of Hyperoxia-induced Pulmonary Endothelial Cell Death Using \u3csup\u3e99m\u3c/sup\u3eTc-Duramycin

    Get PDF
    Introduction 99mTc-duramycin, DU, is a SPECT biomarker of tissue injury identifying cell death. The objective of this study is to investigate the potential of DU imaging to quantify capillary endothelial cell death in rat lung injury resulting from hyperoxia exposure as a model of acute lung injury. Methods Rats were exposed to room air (normoxic) or \u3e 98% O2 for 48 or 60 hours. DU was injected i.v. in anesthetized rats, scintigraphy images were acquired at steady-state, and lung DU uptake was quantified from the images. Post-mortem, the lungs were removed for histological studies. Sequential lung sections were immunostained for caspase activation and endothelial and epithelial cells. Results Lung DU uptake increased significantly (p \u3c 0.001) by 39% and 146% in 48-hr and 60-hr exposed rats, respectively, compared to normoxic rats. There was strong correlation (r2 = 0.82, p = 0.005) between lung DU uptake and the number of cleaved caspase 3 (CC3) positive cells, and endothelial cells accounted for more than 50% of CC3 positive cells in the hyperoxic lungs. Histology revealed preserved lung morphology through 48 hours. By 60 hours there was evidence of edema, and modest neutrophilic infiltrate. Conclusions Rat lung DU uptake in vivo increased after just 48 hours of \u3e 98% O2 exposure, prior to the onset of any substantial evidence of lung injury. These results suggest that apoptotic endothelial cells are the primary contributors to the enhanced DU lung uptake, and support the utility of DU imaging for detecting early endothelial cell death in vivo

    A preferred vision for administering elementary schools : a reflective essay

    Get PDF
    I believe in visionary, instructional, organizational, collaborative, ethical, and political leadership in administrating a school community. I know all students can achieve quality education if the right accommodations are developed for each learning situation. Administrators need to promote educational excellence for all stakeholders. As an administrator, I will promote and advocate for a school community where all students will learn and achieve lifelong knowledge and skills so they can become future leaders in our society. I believe educators must be held accountable for every student to reach their maximum potential in achieving academic and social success. As a principal, my focus will be ensuring that each and every student will learn and achieve at his or her highest potential

    Quantification of Bronchial Circulation Perfusion in Rats

    Get PDF
    The bronchial circulation is thought to be the primary blood supply for pulmonary carcinomas. Thus, we have developed a method for imaging and quantifying changes in perfusion in the rat lung due to development of the bronchial circulation. A dual-modality micro-CT/SPECT system was used to detect change in perfusion in two groups of rats: controls and those with a surgically occluded left pulmonary artery. Both groups were imaged following injections on separate days i) 2mCi of Tc99m labeled macroaggregated albumin (MAA) into the left carotid artery (IA) and ii) a similar injection into the femoral vein (IV). The IA injection resulted in Tc99m accumulation in capillaries of the systemic circulation including the bronchial circulation, whereas the IV resulted in Tc99m accumulation in the pulmonary capillaries. Ordered subset expectation maximization (OSEM) was used to reconstruct the SPECT image volumes and a Feldkamp algorithm was used to reconstruct the micro-CT image volumes. The micro-CT and SPECT volumes were registered, the SPECT image volume was segmented using the right and left lung boundaries defined from the micro-CT volume, and the ratio of IA radioactivity accumulation in the left lung to IV radioactivity accumulation in both lungs was used as a measure of left lung flow via the bronchial circulation. This ratio was ~0.02 for the untreated rats compared to the treated animals that had an increased flow ratio of ~0.21 40 days after left pulmonary artery occlusion. This increase in flow to the occluded left lung via the bronchial circulation suggests this will be a useful model for further investigating antiangiogenic treatments
    corecore