The Effects of a Core Strengthening Program on Functional Walking Endurance and the Perception of Fall Risk in Individuals over the Age of 65

https://digitalcommons.misericordia.edu/research_posters2026/1018/thumbnail.jp

Treatment of Clear Cell Renal Cell Carcinoma (ccRCC) in Interventional Radiology

This project focuses on clear cell renal cell carcinoma (ccRCC) and the role that interventional radiology plays in treating this form of cancer. Clear cell renal cell carcinoma is the most common form of kidney cancer and is often diagnosed using diagnostic imaging such as CT scans, MRIs, and biopsies. This research includes information explaining what ccRCC is, its common symptoms, prognosis, methods of treatment, and what interventional radiology is. Some forms of treatment include surgery and immunotherapy. The main treatment of this project is minimally invasive ablation therapy. Techniques such as radiofrequency ablation, microwave ablation, and cryoablation use imaging guidance to treat tumors while limiting damage to surrounding healthy tissue. These procedures can be especially helpful for patients who may not be good candidates for surgery. Overall, this research highlights how interventional radiology is becoming an important part of cancer treatment and how minimally invasive procedures may improve a patient\u27s outcome and survival rates.https://digitalcommons.misericordia.edu/research_posters2026/1001/thumbnail.jp

Assessing Aerobic and Anaerobic Exercise as Therapies for Sarcopenia

Sarcopenia is an age-related condition represented by progressive changes in muscle physiology that results in the loss of muscle mass and strength. The onset varies amongst individuals and can be influenced by various factors. On the cellular level, mitochondrial dysfunction and disruptions at neuromuscular junctions have been associated with the progression of sarcopenia. The condition ultimately reduces mobility, increases mortality, and hinders quality of life in older populations, necessitating an understanding of effective therapies. Exercise was linked to symptom reduction of sarcopenia. Evidence indicated aerobic exercise and anaerobic exercise influence distinct molecular pathways involved in muscle physiology. Literature assessed the roles of anaerobic and aerobic exercise in influencing molecular pathways, specifically in relation to mitochondrial function, NMJ integrity, and protein synthesis. Findings from the analysis found that aerobic exercise functions through the Sesn2, AMPK/PGC-1α, and β-HB/HCAR2-PPARG signaling pathways. Collectively, these pathways improved mitochondrial biogenesis, reduced oxidative stress, and improved cellular metabolism to limit muscle atrophy. In contrast, anaerobic exercise promoted muscle hypertrophy through PGC-1α4 pathways. PGC-1α4 was involved in the activation of IGF1, repression of myostatin, and enhanced glycolysis which increased hypertrophy. Anaerobic exercise was linked to enhanced satellite cell availability and upregulated neuromuscular communication for improved functionality. In all, anaerobic exercise specifically targets mechanisms for muscle growth and strengthening to counteract the atrophy and muscular decline of sarcopenia, while aerobic exercise creates the cellular conditions necessary for muscular growth. Therefore, both exercise types should be utilized together to generate maximal activation of physiological pathways and most effectively mitigate sarcopenia.https://digitalcommons.misericordia.edu/research_posters2026/1002/thumbnail.jp

Computed Tomography: Contrast Induced Acute Kidney Injury

Abstract Computed tomography is a widely used imaging modality in clinical practice due to its ability to produce detailed cross-sectional images of the body. The administration of iodinated contrast agents enhances the visualization of internal structures and diagnostic accuracy. While pre-contrast scans provide important baseline information, contrast enhanced imaging can further aid in the detection of various pathologies. However, the use of contrast media has raised concerns regarding its potential to contribute to acute kidney injury (AKI), a sudden decline in renal function typically identified in changes in creatinine levels and glomerular filtration rate (GFR). This research reviews current evidence on contrast- associated AKI. Findings from studies indicate that contrast use does not significantly increase the risk of AKI in the general population. Instead, elevated risk is primarily observed in patients with pre-existing kidney disease, reduced GFR, diabetes, advanced age, or dehydration. These results suggest that while contrast is safe, careful patient assessment remains essential. Monitoring kidney function and implementing preventative measures, such as adequate hydration, can help reduce the likelihood of renal complications in higher risk individuals. The study highlights the importance of renal complications in higher risk individuals. Future research should focus on improving risk assessment strategies and further clarifying the relationship between contrast exposure and kidney function in vulnerable population.https://digitalcommons.misericordia.edu/research_posters2026/1005/thumbnail.jp

Mobile Stroke Units: Improving Stroke Care

This project examines the role of Mobile Stroke Units (MSUs) in improving stroke diagnosis and treatment time in emergency care. Strokes occur when blood flow to the brain is interrupted, requiring rapid evaluation to reduce brain damage and improve patient outcomes. This study focuses on how MSUs, which are specialized ambulances equipped with computed tomography (CT) scanners and trained medical personnel, allow imaging and clinical decision-making to occur before hospital arrival. The project highlights the importance of CT imaging in quickly identifying stroke type, including ischemic and hemorrhagic strokes, which directly impacts treatment selection. MSU workflow allows for faster diagnosis, real-time neurologist consultation, and earlier treatment initiation compared to standard emergency medical services (EMS), where imaging and decisions are delayed until hospital arrival. Findings suggest that MSUs significantly reduce treatment delays, improve coordination between healthcare providers, and support better patient outcomes by limiting brain tissue damage. This research also identifies future implications, including expanded use of MSUs in rural areas, advancements in telemedicine, and continued improvements in emergency stroke care systems. Overall, MSUs represent an important advancement in prehospital care by shifting stroke treatment earlier in the care process.https://digitalcommons.misericordia.edu/research_posters2026/1006/thumbnail.jp

Cryoablation to Treat Cancer Utilizing Computed Tomography Guidance

This research examines the effectiveness of cryoablation, a minimally invasive treatment for tumor destruction. Cryoablation works by using freezing temperatures to the targeted tissues, leading to cell damage and eventually cell death. It is being utilized more frequently to treat various cancers, such as: liver, lung, breast, renal, and prostate. This research analyzes current literature and experimental findings to evaluate how cryoablation contributes to improved treatment outcomes and reduced damage to surrounding healthy tissues. Cryoablation offers several advantages over traditional treatment options including, reduced recovery time, lower complication rates, and the ability to precisely target tumors. Imaging guidance through computed tomography during the procedure allows for accurate monitoring and control of the treatment area. The results suggest that cryoablation is an effective alternative for surgery, chemotherapy, and radiation therapy. These findings highlight the growing role of cryoablation in modern oncology. Future research should focus on long-term patient outcomes and continued advancements in imaging and procedural techniques to further improve the safety and effectiveness of cryoablation.https://digitalcommons.misericordia.edu/research_posters2026/1004/thumbnail.jp

The Role of Mammography in Breast Cancer Diagnosis

Abstract Breast cancer remains one of the most common cancers affecting women, making early detection through mammography essential for improving patient outcomes. Breast cancer continues to impact millions of women each year. This capstone project shows the different types of breast cancer and their appearance on mammographic imaging. The main focus includes ductal carcinoma in situ, lobular carcinoma in situ, invasive ductal carcinoma, and invasive lobular carcinoma. The display of images demonstrate the main differences within each type of breast cancer. Each type presents with distinct imaging characteristics. This research aims to improve understanding of the various types of breast cancer and emphasize the importance of mammography for early detection and education. Increased awareness of imaging characteristics can lead to earlier detection, improved patient care, and better outcomes. This research also highlights the importance of proper positioning and image quality. The differences between screening and diagnostic mammograms are highlighted within the research and show how important taking care of your health should be. Keywords: detection, breast cancer, increased awarenesshttps://digitalcommons.misericordia.edu/research_posters2026/1007/thumbnail.jp

Magnetic Resonance Imaging of Multiple Sclerosis

Magnetic resonance imaging (MRI) is a key tool in the diagnosis and monitoring of multiple sclerosis (MS). MRI allows doctors to see lesions in the brain and spinal cord and track disease activity over time. MS is an autoimmune neuroinflammatory disorder affecting the central nervous system. MS affects an estimated 900,000 people in the United States. MS most often develops in young adults, typically between the ages of 20 and 30. MS can lead to physical disability, cognitive difficulties, and a reduced quality of life. Globally, studies show that the incidence and burden of MS have increased over the past decades. This highlights the importance of early diagnosis and effective monitoring for patient outcomes. MS is treated with medication to slow the progression of the disease, steroids for flare-ups, treatment to manage symptoms, therapy to help with movement and daily activities, and healthy lifestyle support. Although MRI is effective for monitoring and detecting MS plaques, ongoing research suggests that future advancements in MRI techniques and biomarkers may improve early diagnosis and help predict disease progression more accurately.https://digitalcommons.misericordia.edu/research_posters2026/1009/thumbnail.jp

How AI Is Used in Computed Tomography

This project explains artificial intelligence (AI) and how it is used in computed tomography (CT). AI and CT are both defined, and the project shows how both relate to each other to create a better overall outcome of the studies. Different uses of AI are demonstrated in the following ways: patient positioning, 3D analysis, and within a lung screening study. Even though there is only one example of using AI in a lung screening study, AI can be used in almost every study to either measure, identify, or locate. Arteries, nodules, and tumors are some examples that AI can detect within CT, therefore making it an important new aspect. A few advantages of AI are in the project such as it can improve efficiency and productivity. A few disadvantages are also listed such as making sure human expertise doesn’t go away with the addition of AI. Both advantages and disadvantages give certain viewpoints to decide whether AI should stay and continue to grow in the medical imaging field.https://digitalcommons.misericordia.edu/research_posters2026/1010/thumbnail.jp

Contrast-Enhanced Spectral Mammography

Contrast-Enhanced Spectral Mammography (CESM) is an advanced breast imaging technique that enhances the detection and characterization of breast lesions, more specifically in patients with dense breast tissue where conventional mammography is limited. This research explores the principles, clinical applications, advantages, and limitations of CESM. The technique utilizes dual-energy imaging combined with intravenous iodinated contrast to highlight areas of increased vascularity, which are often seen with malignancy. CESM provides both anatomical and functional imaging in one efficient examination. Studies demonstrate that CESM offers higher sensitivity and comparable specificity to traditional mammography, with diagnostic performance approaching that of breast MRI while being more cost-effective and accessible. Clinical applications include lesion detection, preoperative staging, and monitoring treatment response. Despite its benefits, CESM does present some limitations such as increased radiation dose and risks associated with contrast administration. Emerging advancements in artificial intelligence are further enhancing diagnostic accuracy and workflow efficiency. The findings suggest that CESM is a valuable tool in breast cancer imaging and has the potential to greatly improve clinical decision-making. Future research should focus on optimizing patient selection, minimizing risks, and integrating artificial intelligence to further advance the capabilities of CESM.https://digitalcommons.misericordia.edu/research_posters2026/1020/thumbnail.jp