Remote device access in the new accelerator controls middleware

This paper presents the Remote Device Access (RDA) package developed at CERN in the framework of the joint PS/SL Controls Middleware project. The package design reflects the Accelerator Device Model in which devices, named entities in the control system, can be controlled via properties. RDA implements this model in a distributed environment with devices residing in servers that can run anywhere in the controls network. It provides a location-independent and reliable access to the devices from control programs. By invoking the device access methods, clients can read, write and subscribe to device property values. We describe the architecture and design of RDA its API, and CORBA-based implementations in Java and C++. First applications of RDA in the CERN accelerator control systems are described as well

GT: Picking up the Truth from the Ground for Internet Traffic

Much of Internet traffic modeling, firewall, and intrusion detection research requires traces where some ground truth regarding application and protocol is associated with each packet or flow. This paper presents the design, development and experimental evaluation of gt, an open source software toolset for associating ground truth information with Internet traffic traces. By probing the monitored host's kernel to obtain information on active Internet sessions, gt gathers ground truth at the application level. Preliminary exper- imental results show that gt's effectiveness comes at little cost in terms of overhead on the hosting machines. Furthermore, when coupled with other packet inspection mechanisms, gt can derive ground truth not only in terms of applications (e.g., e-mail), but also in terms of protocols (e.g., SMTP vs. POP3

Thermal convection in fluidized granular systems

Thermal convection is observed in molecular dynamic simulation of a fluidized granular system of nearly elastic hard disks moving under gravity, inside a rectangular box. Boundaries introduce no shearing or time dependence, but the energy injection comes from a slip (shear-free) thermalizing base. The top wall is perfectly elastic and lateral boundaries are either elastic or periodic. The observed convection comes from the effect of gravity and the spontaneous granular temperature gradient that the system dynamically develops.Comment: 4 pages, 5 figure

2n Gamete formation in the genus Brachiaria (Poaceae: Paniceae).

Microsporogenesis of several Brachiaria species of the Brazilian collection at Embrapa Beef Cattle has been analyzed in detail. This paper reports abnormal cytokinesis in three accessions of three different species (Brachiaria humidicola, 2n = 4x = 36, Brachiaria decumbens, 2n = 4x = 36, and Brachiaria dura, 2n = 6x = 54). Chromosomes paired in bi-, tri-, and quadrivalents in these accessions, whereas chromosome segregation at meiosis I was characterized by exclusion of laggards as micronuclei. In a high number of meiocytes, the first sign of cytokinesis appeared only in metaphase II and did not divide the meiocyte into a dyad. Total absence of cytokinesis was also detected among meiocytes in the second division. Since in both cases the two metaphase plates were very close, they favored the rejoining of chromosome sets after anaphase II and formed a restitutional nucleus in telophase II. Second cytokinesis occurred after telophase II in most meiocytes. Monads, dyads, and triads with n or 2n nuclei were observed among meiotic products. The 2n gametes observed correspond to the first division restitution (FDR). The number of affected cells in each accession was variable, but the number of microspores with restitutional nucleus, including those scored in tetrads and the released ones, did not exceed 9%. Although polyploidy is common in the genus Brachiaria, its origin is still unclear. Current results suggest that 2n gametes may have contributed to the evolutionary history of the genus.CNPGC

Recent cropping frequency, expansion, and abandonment in Mato Grosso, Brazil had selective land characteristics

This letter uses satellite remote sensing to examine patterns of cropland expansion, cropland abandonment, and changing cropping frequency in Mato Grosso, Brazil from 2001 to 2011. During this period, Mato Grosso emerged as a globally important center of agricultural production. In 2001, 3.3 million hectares of mechanized agriculture were cultivated in Mato Grosso, of which 500 000 hectares had two commercial crops per growing season (double cropping). By 2011, Mato Grosso had 5.8 million hectares of mechanized agriculture, of which 2.9 million hectares were double cropped. We found these agricultural changes to be selective with respect to land attributes —significant differences (p \u3c 0.001) existed between the land attributes of agriculture versus nonagriculture, single cropping versus double cropping, and expansion versus abandonment. Many of the land attributes (elevation, slope, maximum temperature, minimum temperature, initial soy transport costs, and soil) that were associated with an increased likelihood of expansion were associated with a decreased likelihood of abandonment (p \u3c 0.001). While land similar to agriculture and double cropping in 2001 was much more likely to be developed for agriculture than all other land, new cropland shifted to hotter, drier, lower locations that were more isolated from agricultural infrastructure (p \u3c 0.001). The scarcity of high quality remaining agricultural land available for agricultural expansion in Mato Grosso could be contributing to the slowdown in agricultural expansion observed there over 2006 to 2011. Land use policy analyses should control for land scarcity constraints on agricultural expansion

Research Directions in Network Service Chaining

Network Service Chaining (NSC) is a service deployment concept that promises increased flexibility and cost efficiency for future carrier networks. NSC has received considerable attention in the standardization and research communities lately. However, NSC is largely undefined in the peer-reviewed literature. In fact, a literature review reveals that the role of NSC enabling technologies is up for discussion, and so are the key research challenges lying ahead. This paper addresses these topics by motivating our research interest towards advanced dynamic NSC and detailing the main aspects to be considered in the context of carrier-grade telecommunication networks. We present design considerations and system requirements alongside use cases that illustrate the advantages of adopting NSC. We detail prominent research challenges during the typical lifecycle of a network service chain in an operational telecommunications network, including service chain description, programming, deployment, and debugging, and summarize our security considerations. We conclude this paper with an outlook on future work in this are

Non-Newtonian Couette-Poiseuille flow of a dilute gas

The steady state of a dilute gas enclosed between two infinite parallel plates in relative motion and under the action of a uniform body force parallel to the plates is considered. The Bhatnagar-Gross-Krook model kinetic equation is analytically solved for this Couette-Poiseuille flow to first order in the force and for arbitrary values of the Knudsen number associated with the shear rate. This allows us to investigate the influence of the external force on the non-Newtonian properties of the Couette flow. Moreover, the Couette-Poiseuille flow is analyzed when the shear-rate Knudsen number and the scaled force are of the same order and terms up to second order are retained. In this way, the transition from the bimodal temperature profile characteristic of the pure force-driven Poiseuille flow to the parabolic profile characteristic of the pure Couette flow through several intermediate stages in the Couette-Poiseuille flow are described. A critical comparison with the Navier-Stokes solution of the problem is carried out.Comment: 24 pages, 5 figures; v2: discussion on boundary conditions added; 10 additional references. Published in a special issue of the journal "Kinetic and Related Models" dedicated to the memory of Carlo Cercignan

Understanding the modifiable health systems barriers to hypertension management in Malaysia: a multi-method health systems appraisal approach.

BACKGROUND: The growing burden of non-communicable diseases in middle-income countries demands models of care that are appropriate to local contexts and acceptable to patients in order to be effective. We describe a multi-method health system appraisal to inform the design of an intervention that will be used in a cluster randomized controlled trial to improve hypertension control in Malaysia. METHODS: A health systems appraisal was undertaken in the capital, Kuala Lumpur, and poorer-resourced rural sites in Peninsular Malaysia and Sabah. Building on two systematic reviews of barriers to hypertension control, a conceptual framework was developed that guided analysis of survey data, documentary review and semi-structured interviews with key informants, health professionals and patients. The analysis followed the patients as they move through the health system, exploring the main modifiable system-level barriers to effective hypertension management, and seeking to explain obstacles to improved access and health outcomes. RESULTS: The study highlighted the need for the proposed intervention to take account of how Malaysian patients seek treatment in both the public and private sectors, and from western and various traditional practitioners, with many patients choosing to seek care across different services. Patients typically choose private care if they can afford to, while others attend heavily subsidised public clinics. Public hypertension clinics are often overwhelmed by numbers of patients attending, so health workers have little time to engage effectively with patients. Treatment adherence is poor, with a widespread belief, stemming from concepts of traditional medicine, that hypertension is a transient disturbance rather than a permanent asymptomatic condition. Drug supplies can be erratic in rural areas. Hypertension awareness and education material are limited, and what exist are poorly developed and ineffective. CONCLUSION: Despite having a relatively well funded health system offering good access to care, Malaysia's health system still has significant barriers to effective hypertension management. DISCUSSION: The study uncovered major patient-related barriers to the detection and control of hypertension which will have an impact on the design and implementation of any hypertension intervention. Appropriate models of care must take account of the patient modifiable health systems barriers if they are to have any realistic chance of success; these findings are relevant to many countries seeking to effectively control hypertension despite resource constraints

An African-specific haplotype in MRGPRX4 is associated with menthol cigarette smoking

In the U.S., more than 80% of African-American smokers use mentholated cigarettes, compared to less than 30% of Caucasian smokers. The reasons for these differences are not well understood. To determine if genetic variation contributes to mentholated cigarette smoking, we performed an exome-wide association analysis in a multiethnic population-based sample from Dallas, TX (N = 561). Findings were replicated in an independent cohort of African Americans from Washington, DC (N = 741). We identified a haplotype of MRGPRX4 (composed of rs7102322[G], encoding N245S, and rs61733596[G], T43T), that was associated with a 5-to-8 fold increase in the odds of menthol cigarette smoking. The variants are present solely in persons of African ancestry. Functional studies indicated that the variant G protein-coupled receptor encoded by MRGPRX4 displays reduced agonism in both arrestin-based and G protein-based assays, and alteration of agonism by menthol. These data indicate that genetic variation in MRGPRX4 contributes to inter-individual and inter-ethnic differences in the preference for mentholated cigarettes, and that the existence of genetic factors predisposing vulnerable populations to mentholated cigarette smoking can inform tobacco control and public health policies