Weather and resource information as tools for dealing with farmer–pastoralist conflicts in the Sahel

Conflicts between pastoralists and farmers in the Sahel mainly arise from competition over land and water resources or because of livestock damage to crops. Rather than being linked to larger environmental change processes such as climate change, conflicts are often caused by inappropriate zoning of land, governance and unequal power relations between stakeholders. However, conflicts may be affected by more short-term weather and resource information that guide mobility of pastoralists. In this paper, we therefore explore if improved weather and resource information and improvement in its communication could prevent conflicts or reduce their severity. Based on a survey of key stakeholders involved in dissemination of weather and resource information and studies on pastoral access to and use of information, we conclude that improved information may both reduce and increase the level of conflict, depending on the context. Communication of information will need to go beyond just the weather and resource information and also include the multiple options for herd movements as well as providing information on herd crowding and potential conflict areas

Leucine supplementation differentially enhances pancreatic cancer growth in lean and overweight mice

Kristyn A Liu1†, Laura M Lashinger1†, Audrey J Rasmussen1† and Stephen D Hursting12* Author Affiliations 1 Department of Nutritional Sciences, University of Texas at Austin, Austin, TX 78723, USA 2 Department of Molecular Carcinogenesis, University of Texas M.D. Anderson Cancer Center, 1808 Park Road 1c, Smithville, TX 78957, USABackground: The risk of pancreatic cancer, the 4th deadliest cancer for both men and women in the United States, is increased by obesity. Calorie restriction (CR) is a well-known dietary regimen that prevents or reverses obesity and suppresses tumorigenesis in a variety of animal models, at least in part via inhibition of mammalian target of rapamycin (mTOR) signaling. Branched-chain amino acids (BCAA), especially leucine, activate mTOR and enhance growth and proliferation of myocytes and epithelial cells, which is why leucine is a popular supplement among athletes. Leucine is also increasingly being used as a treatment for pancreatic cancer cachexia, but the effects of leucine supplementation on pancreatic tumor growth have not been elucidated. Results: Supplementation with leucine increased pancreatic tumor growth in both lean (104 ± 17 mm3 versus 46 ± 13 mm3; P <0.05) and overweight (367 ± 45 mm3 versus 230 ± 39 mm3; P <0.01) mice, but tumor enhancement was associated with different biological outcomes depending on the diet. In the lean mice, leucine increased phosphorylation of mTOR and downstream effector S6 ribosomal protein, but in the overweight mice, leucine reduced glucose clearance and thus increased the amount of circulating glucose available to the tumor. Conclusion: These findings show that leucine supplementation enhances tumor growth in both lean and overweight mice through diet-dependent effects in a murine model of pancreatic cancer, suggesting caution against the clinical use of leucine supplementation for the purposes of skeletal muscle enhancement in cachectic patients.Nutritional Science

Journal of African Christian Biography

A publication of the Dictionary of African Christian Biography with U.S. offices located at the Center for Global Christianity and Mission at Boston University. This issue focuses on: WOMEN --- 1. Biographies of Kimpa Vita by Norbert Brockman, Mark R. Lipschutz and R. Kent Rasmussen, and Tsimba Mabiala. 2. "The Life and Visions of Krəstos Śämra, a Fifteenth-Century Ethiopian Woman Saint,"--chapter from African Christian Biography: Stories, Lives and Challenges (D. L. Robert, editor) by Wendy Laura Belcher 3. "Queen Njinga and Her Faiths: Religion and Politics in Seventeenth-Century Angola"--chapter from African Christian Biography: Stories, Lives and Challenges (D. L. Robert, editor) by Linda Heywood. 4. Book Notes, by B. Restric

A theory-based longitudinal investigation examining predictors of self-harm in adolescents with and without bereavement experiences

Background Research has demonstrated that exposure to suicide can lead to increased vulnerability for self-harm or suicide. As a result, ideation to action models of suicide (e.g., the Integrated Motivational-Volitional Model of Suicide; IMV) recognise exposure as a significant risk factor which may be implicated in the translation of thoughts into actions. However, few studies have tested this theoretical link explicitly within an adolescent population, and examined how it compares to other types of bereavements. Methods A 6-month prospective questionnaire study was conducted with 185 Scottish adolescents aged 11-17 (113 adolescents also completed the questionnaire at follow-up). The questionnaire included measures on experiences with bereavement and lifetime engagement in self-harm, as well as measures of defeat, entrapment, social support, coping, and other psychological variables. Results At baseline, 12% of young people reported exposure to a suicide death, and 61% to a non-suicide death. In addition, 21% of pupils reported ever engaging in self-harm, while 23% had experienced self-harm ideation without engaging in it. Cross-sectional multivariate logistic regressions showed that family social support, glorifying/normalising beliefs about suicide, and family self-harm were significantly associated with self-harm group membership (control, ideation, or enactment groups). At follow-up, 10% of pupils reported exposure to a suicide death and 16% to a non-suicide death for the first time. A total of 26% of the sample reported self-harm at T2 (11% of participants for the first time), and 24% reported self-harm ideation without engaging in it. Multivariate analyses found that self-harm ideation and family self-harm at baseline were the only variables to predict self-harm group membership prospectively, in the expected directions. Bereavement experiences, whether by suicide or non-suicide, did not predict self-harm group status at baseline nor at follow-up. Conclusions This study provides support for the validity of a theoretical model of suicide, even though predictive ability over the 6-months period was limited. Although difficulties with recruitment may have limited the statistical power, this study provides insight into the prevalence and experiences of suicide bereavement among adolescents and the factors related to the onset and maintenance of self-harm

Governing for ecosystem health and human wellbeing

Governance arrangements and processes influence access to and benefits from ecosystem services, and therefore the potential for ecosystem services to alleviate poverty. Governance also then influences the health of ecosystems. This chapter learns from decades of governance-related research to identify how to make ecosystem governance more effectively ‘pro-poor’. It is informed by a systematic mapping of literature related to governance of ecosystem services and renewable natural resources for improved wellbeing and poverty alleviation, expert interviews and a workshop with government and non-government actors across a range of sectors from both North and South. The chapter is organised around the concept of trade-offs, considering first ecosystem-focused approaches, then rights-based approaches and lastly, participatory approaches to governance. The chapter further addresses the relevance of scale and multiple administrative levels (multi-level governance) and the importance of informal, or socially embedded, institutions. The chapter concludes that there is no single governance approach that can definitively deliver on improved ecosystem health and human wellbeing, that trade-offs are inevitable and governance is therefore an inherently political process