The Protective Effect of the Mediterranean Diet: Focus on Cancer and Cardiovascular Risk

The lower occurrence of cancer and cardiovascular disease in the population around the Mediterranean basin has been linked to the dietary habits of the region. Indeed, this so-called Mediterranean diet is essentially different from the diets consumed in Western and Northern European countries and is rich in nuts, fruits, vegetables, legumes, whole-wheat bread, fish, and olive oil, with moderate amounts of red wine, which is mainly consumed during meals. Although a variety of cultural and religious traditions exist among the peoples of the Mediterranean area, olive oil, fish, and red wine hold a traditional and central position in the culinary routines of the region. The components of the diet contain an ample source of molecules with antioxidant and anti-inflammatory actions, among which omega-3 fatty acids, oleic acid, and phenolic compounds hold a prominent place. This review will summarize the results of important epidemiological studies that have investigated the protective effect of fish and olive oil on the risk of breast, prostate, and colorectal cancer and of wine on the risk of cardiovascular disease. The present review also aims to elucidate the various mechanisms by which various dietary components exhibit their beneficial action. In this respect, emphasis will be placed on the properties of omega-3 fatty acids from fish, oleic acid from olive oil, and phenolic compounds from olive oil and red wine

Noise in Electron Devices

Contains reports on one research project.Joint Services Electronics Programs (U. S. Army, U. S. Navy, and U. S. Air Force) under Contract DA 36-039-AMC-03200(E

Quantifying Volatility Reduction in German Day-ahead Spot Market in the Period 2006 through 2016

In Europe, Germany is taking the lead in the switch from the conventional to renewable energy. This poses new challenges as wind and solar energy are fundamentally intermittent, weather-dependent and less predictable. It is therefore of considerable interest to investigate the evolution of price volatility in this post-transition era. There are a number of reasons, however, that makes the practical studies difficult. For instance, EPEX prices can be zero or negative. Consequently, the standard approach in financial time series analysis to switch to logarithmic measures is inapplicable. Furthermore, in contrast to the stock market prices which are only available for trading days, EPEX prices cover the whole year, including weekends and holidays. Accordingly, there is a lot of underlying variability in the data which has nothing to do with volatility, but simply reflects diurnal activity patterns. An important distinction of the present work is the application of matrix decomposition techniques, namely the singular value decomposition (SVD), for defining an alternative notion of volatility. This approach is systematically more robust toward outliers and also the diurnal patterns. Our observations show that the day-ahead market is becoming less volatile in recent years

Regularisation for PCA- and SVD-type matrix factorisations

Singular Value Decomposition (SVD) and its close relative, Principal Component Analysis (PCA), are well-known linear matrix decomposition techniques that are widely used in applications such as dimension reduction and clustering. However, an important limitation of SVD/PCA is its sensitivity to noise in the input data. In this paper, we take another look at the problem of regularisation and show that different formulations of the minimisation problem lead to qualitatively different solutions

Pairing-excitation versus intruder states in 68Ni and 90Zr

A discussion on the nature of the 0+ states in 68Ni (Z=28, N=40) is presented and a comparison is made with its valence counterpart 90Zr (Z=40, N=50). Evidence is given for a 0+ proton intruder state at only ~2.2 MeV excitation energy in 68Ni, while the analogous neutron intruder states in 90Zr reside at 4126 keV and 5441 keV. The application of a shell-model description of 0+ intruder states reveals that many pair-scattered neutrons across N=40 have to be involved to explain the low excitation energy of the proton-intruder configuration in 68Ni.Comment: 10 pages, 2 figures, 1 tabl