1,803 research outputs found

    La Fotoprotección en la sociedad madrileña

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    Con la llegada del verano a todos nos apetece tomar el sol y lucir una piel más bronceada. El sol es una fuente de energía imprescindible que tiene múltiples beneficios como la síntesis de vitamina D, favorecer la circulación sanguínea e influir positivamente en nuestro estado de ánimo entre otras cosas. Sin embargo, sus radiaciones pueden tener efectos nocivos sobre la piel como quemaduras, envejecimiento prematuro, afecciones oculares, fotodermatosis y cáncer de piel. Estos efectos pueden producirse como consecuencia de una exposición inadecuada, excesiva e incontrolada al sol. Por eso, nos ha parecido interesante conocer los hábitos de la población respecto al uso de protectores solares. Debemos tener en cuenta que la radiación solar emitida por el sol es absorbida parcialmente por la capa de ozono, las nubes y la contaminación atmosférica. Todo ello actúa como un filtro sobre las radiaciones solares. Actualmente se está produciendo un adelgazamiento de la capa de ozono, que se está relacionando con el aumento de los efectos nocivos de las radiaciones del sol. Finalmente para protegernos de los rayos solares debemos utilizar fotoprotectores y otras medidas (gorros, gafas de sol, sombrilla…). Seguir una dieta rica en beta-carotenos y vitaminas también es aconsejable, en este sentido existen productos comerciales para complementar la dieta con estos nutrientes. Hemos centrado este trabajo en conocer el tipo de población que utiliza mayoritariamente protectores solares y el modo en que está lo utiliza. Para poder mejorar la atención farmacéutica sobre este tema debemos conocer cuáles son los hábitos de la población sobre la aplicación de los fotoprotectores y el conocimiento que tiene de su uso y aplicación, pudiendo incidir en las carencias que encontremos. Además, hemos querido saber qué tipo de fototipo de piel tienen los individuos encuestados, y así poder aconsejar la protección adecuada para su piel

    Proyecto de Investigación: La formación de los paisajes agrarios del Noroeste peninsular durante la Edad Media (siglos V al XII)

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    Presentamos los objetivos y los primeros resultados del proyecto de investigación La formación de los paisajes del Noroeste Peninsular durante la Edad Media (siglos V al XII). Exponemos los presupuestos teóricos y metodológicos de la arqueología agraria y nos acercamos a los resultados preliminares obtenidos en los tres casos de estudio abordados en nuestra investigación. [ABSTRACT] The paper introduces the aims and the preliminary outcomes of the research project entitled ‘The formation of agricultural landscapes in north western Iberia during the Middle Ages (V – XII centuries)’. Also, the text sets out the theoretical and methodological underpinnings of agrarian archaeology. Finally, the paper presents and explains the results achieved hitherto in the three archaeological case studies under investigation

    Global increase of the intensity of tropical cyclones under global warming based on their maximum potential intensity and CMIP6 models

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    Future changes in the intensity of tropical cyclones (TCs) under global warming are uncertain, although several studies have projected an upward trend in TC intensity. In this study, we examined the changes in the strength of TCs in the twenty-first century based on the Hurricane Maximum Potential Intensity (HuMPI) model forced with the sea surface temperature (SST) from the bias-corrected CMIP6 dataset. We first investigated the relationship between the mean lifetime maximum intensity (LMI) of major hurricanes (MHs) and the maximum potential intensity (MPI) using the SST from the Daily Optimum Interpolation SST database. The LMI of MHs and the MPI in the last two decades was, on average, 2–3% higher than mean values in the sub-period 1982–2000, suggesting a relationship between changes in MPI and LMI. From our findings, the projected changes in TC intensity in the near-future period (2016–2040) will be almost similar for SSP2-4.5 and SSP5-8.5 climate scenarios. However, TCs will be 9.5% and 17% more intense by the end (2071–2100) of the twenty-first century under both climate scenarios, respectively, compared with the mean intensity over the historical period (1985–2014). In addition, the MPI response to a warmed sea surface temperature per degree of warming is a 5–7% increase in maximum potential wind speed. These results should be interpreted as a projection of changes in TC intensity under global warming since the HuMPI formulation does not include environmental factors (i.e., vertical wind shear, mid-level moisture content and environmental stratification) that influence TC long-term intensity variations.Universidade de Vigo/CISU

    Mining Web Pages Using Features of Rendering HTML Elements in the Web Browser

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    The Web is the largest repository of useful information available for human users, but it is usual that Web Pages do not provide an API to get access to its information automatically. In order to solve this problem, Information Extractors are developed. We present a new methodology to induce Information Extractors from the Web. It is based on rendering HTML elements in the Web browser. The methodology uses a KDD process to mining a dataset with features of the elements in the Web page. An experimentation over 10 web sites has been made and the results show the effectiveness of the methodology.Ministerio de Ciencia y Tecnología TIN2007-64119Junta de Andalucía P07-TIC-02602Junta de Andalucía P08-TIC-410

    Regioselective synthesis of elusive 4,9-Dihydro-1H-Carbazoles by gold-catalyzed cycloisomerization of 3-Allenylmethylindoles

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    A general and efficient synthesis of 4,9-dihydro- 1H-carbazoles from 3-allenylmethylindoles is reported. The process, catalyzed by a cationic gold(I) complex, involves a formal C2−H bond activation of the indole unit by reaction with the allene. The nature of the substituents at the allylic and terminal positions of the allene moiety has a crucial effect on the regioselectivity of the cyclization, which is also influenced by the catalyst and the solvent employed. Moreover, some evidence of the contribution of different reaction routes is provided, which led us to propose a plausible multipathway mechanism consistent with all of the results described.MICINN and FEDER (CTQ2010-15358 and CTQ2009-09949/BQU) for financial support. E.A. thanks MEC for an FPU predoctoral fellowship. P.G.-G. and M.A.F.-R. thank MICINN for "Juan de la Cierva" and "Ramon y Cajal" contractsThis document is the Accepted Manuscript version of a Published Work that appeared in final form in Journal of organic chemistry, copyright © American Chemical Society after peer review and technical editing by the publisher

    Bartonella Endocarditis in Spain: Case Reports of 21 Cases

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    Endocarditis por Bartonella; Endocarditis infecciosaBartonella endocarditis; Infective endocarditisEndocarditis per Bartonella; Endocarditis infecciosaBlood culture negative endocarditis (BCNE) is frequent in infective endocarditis (IE). One of the causes of BCNE is fastidious microorganisms, such as Bartonella spp. The aim of this study was to describe the epidemiologic, clinical characteristics, management and outcomes of patients with Bartonella IE from the “Spanish Collaboration on Endocarditis-Grupo de Apoyo al Manejo de la Endocarditis infecciosa en España (GAMES)”cohort. Here we presented 21 cases of Bartonella IE. This represents 0.3% of a total of 5590 cases and 2% of the BCNE from the GAMES cohort. 62% were due to Bartonella henselae and 38% to Bartonella quintana. Cardiac failure was the main presenting form (61.5% in B. hensalae, 87.5% in B. quintana IE) and the aortic valve was affected in 85% of the cases (76% in B. henselae, 100% in B. quintana IE). Typical signs such as fever were recorded in less than 40% of patients. Echocardiography showed vegetations in 92% and 100% of the patients with B. henselae and B. quintana, respectively. Culture was positive only in one patient and the remaining were diagnosed by serology and PCR. PCR was the most useful tool allowing for diagnosis in 16 patients (100% of the studied valves). Serology, at titers recommended by guidelines, only coincided with PCR in 52.4%. Antimicrobial therapy, in different combinations, was used in all cases. Surgery was performed in 76% of the patients. No in-hospital mortality was observed. One-year mortality was 9.4%. This article remarks the importance for investigating the presence of Bartonella infection as causative agent in all BCNE since the diagnosis needs specific microbiological tools and patients could benefit of a specific treatment

    Bispyrrolidinoindoline Epi(poly)thiodioxopiperazines (BPI-ETPs) and simplified mimetics: structural characterization, bioactivities, and total synthesis

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    Within the 2,5-dioxopiperazine-containing natural products generated by “head-to-tail” cyclization of peptides, those derived from tryptophan allow further structural diversification due to the rich chemical reactivity of the indole heterocycle, which can generate tetracyclic fragments of hexahydropyrrolo[2,3-b]indole or pyrrolidinoindoline skeleton fused to the 2,5-dioxopiperazine. Even more complex are the dimeric bispyrrolidinoindoline epi(poly)thiodioxopiperazines (BPI-ETPs), since they feature transannular (poly)sulfide bridges connecting C3 and C6 of their 2,5-dioxopiperazine rings. Homo- and heterodimers composed of diastereomeric epi(poly)thiodioxopiperazines increase the complexity of the family. Furthermore, putative biogenetically generated downstream metabolites with C11 and C11’-hydroxylated cores, as well as deoxygenated and/or oxidized side chain counterparts, have also been described. The isolation of these complex polycyclic tryptophan-derived alkaloids from the classical sources, their structural characterization, the description of the relevant biological activities and putative biogenetic routes, and the synthetic efforts to generate and confirm their structures and also to prepare and further evaluate structurally simple analogs will be reported.Xunta de Galicia | Ref. GRC ED431C 2021/045Ministerio de Economía | Ref. PID2019-107855RB-I00Xunta de Galicia | Ref. ED-431G/02-FEDE

    La inserción profesional en el ámbito académico de los estudiantes avanzados de la carrera de Sociología de la UBA: ¿un sueño imposible?

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    En esta ponencia se analiza las expectativas de inserción en el ámbito académico de los estudiantes avanzados de la carrera de sociología de la UBA. Para ello se utilizarán los resultados provenientes del proyecto UBACyT “La enseñanza de metodología de investigación en sociología: una mirada desde los estudiantes”. A través de dicha investigación, se ha intentado reflexionar acerca de aspectos vinculados a la formación metodológica ofrecida por la Carrera de Sociología, desde la perspectiva de los estudiantes a medida que progresan en su cursada. Una de las líneas derivadas del trabajo investigativo mencionado, estudia las expectativas de inserción profesional entre los estudiantes que se encuentran próximos a su egreso, siendo esta temática la enfocada en esta ponencia.Mesa 29: Juventud divino tesoro: jóvenes, trabajo y educación.Facultad de Humanidades y Ciencias de la Educació
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