HEAT TRANSFER ANALYSIS OF HEAT GENERATING WIRE USING FINITE ELEMENT METHOD

This paper describes the numerical results of the heat transfer from heat generating wire at different conditions by finite element method. The parametric effects on heat transfer were investigated. The varied parameters included ambient conditions, as well as the shape of the cross-section. The numerical results show that the type of the medium where the heat generating wire immerges has strong effects on the heatdissipation rate. As the size of the diameter the heat dissipation to the ambient is decreased. The effects of free convection conditions on the wire surface are also significant. However, the effect of the shape of the cross-section is not very strong. The results presented in this paper provide useful information for the application of heat generating wire

Intraocular Lens Opacification following Intracameral Injection of Recombinant Tissue Plasminogen Activator to Treat Inflammatory Membranes after Cataract Surgery

Purpose. To report 7 cases of intraocular lens (IOL) opacification following treatment of postoperative anterior chamber fibrin with recombinant tissue plasminogen activator (rtPA) after cataract surgery. Methods. Retrospective case series of 7 eyes in 7 patients who developed IOL opacification after receiving rtPA for anterior chamber inflammatory membrane formation resulting from phacoemulsification cataract surgery. Three explanted IOLs were investigated with light microscopy, histochemical analysis, scanning electron microscopy, and X-ray spectrometry. Results. All patients underwent uncomplicated cataract surgery and posterior chamber hydrophilic IOL implantation. Anterior chamber inflammatory membranes developed between 1 and 4 weeks of surgery and were treated with intracameral rtPA. IOL opacification was noted between 4 weeks and 6 years after rtPA treatment with reduced visual acuity, and IOL exchange was carried out in 3 patients. Light microscopy evaluation revealed diffuse fine granular deposits on the anterior surface/subsurface of IOL optic that stained positive for calcium salts. Scanning electron microscopy (SEM) and energy-dispersive X-ray spectrometry (EDS) confirmed the presence of calcium and phosphate on the IOL. Conclusions. Intracameral rtPA, though rapidly effective in the treatment of anterior chamber inflammatory membranes following cataract surgery, may be associated with IOL opacification

Oxy-functionalization of olefins with neat and heterogenized binuclear V(IV)O and Fe(II) complexes: effect of steric hindrance on product selectivity and output in homogeneous and heterogeneous phase

Neat {[VO(sal2bz)]2; [Fe(sal2bz)(H2O)2]2·2H2O} and zeolite-Y immobilized {[VO(sal2bz)]2-Y; [Fe(sal2bz)(H2O)2]2-Y} binuclear complexes have been prepared and characterized by spectroscopic techniques (IR, UV–vis), elemental analyses (CHN, ICP-OES), thermal study (TGA), scanning electron micrograph (SEM), adsorption study (BET) and X-ray diffraction (XRD) patterns. Neat (homogeneous) and immobilized (heterogeneous) complexes were employed as catalysts in the oxidation of olefins, namely, cyclohexene, limonene and α-pinene in the presence of 30% hydrogen peroxide. 100% conversion of cyclohexene and α-pinene was obtained while limonene was oxidized up to 90%. Homogeneous catalysts showed highly selective result as neat [VO(sal2bz)]2 complex has provided 87% cyclohexane-1,2-diol and neat [Fe(sal2bz)(H2O)2]2·2H2O complex has provided 79% verbenone in oxidation of cyclohexene and α-pinene, respectively. We have observed that due to steric hindrance, formation of olefinic oxidation products increases on moving from α-pinene to limonene and limonene to cyclohexene. Additionally. recovered heterogeneous catalysts showed intact results up to two consecutive runs. Probable catalytic mechanism has been proposed for oxidation of cyclohexene

Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19

IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19. Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19. DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 non–critically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022). INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (n = 257), ARB (n = 248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; n = 10), or no RAS inhibitor (control; n = 264) for up to 10 days. MAIN OUTCOMES AND MEASURES The primary outcome was organ support–free days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes. RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ support–free days among critically ill patients was 10 (–1 to 16) in the ACE inhibitor group (n = 231), 8 (–1 to 17) in the ARB group (n = 217), and 12 (0 to 17) in the control group (n = 231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ support–free days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively). CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes. TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570

Image1_Efficient and eco-friendly treatment of wastewater through sustainable purification using agricultural waste and coagulation kinetic modelling.JPEG

This scientific manuscript presents a comprehensive investigation into the purification of municipal sewage water through the utilization of agricultural waste materials [Arachis hypogaea shells (AHS), Triticum aestivum straw (TAS), and Gossypium herbaceum shells (GHS)]. The treatment process involved a modified approach with 24 hs of aeration and the addition of 1 gm of agricultural waste biomaterials. The performance of the bio-coagulant was evaluated by monitoring the reduction of physico−chemical parameters. AHS exhibited remarkable turbidity removal efficiency of 93.37%, supported by pseudo−first and pseudo−second−order kinetic modelling. The application of agricultural waste materials significantly reduced key parameters, including solids (up to 70%–80%), dissolved oxygen (DO) (50%), biological oxygen demand (BOD) and chemical oxygen demand (COD) (up to 90%). Principal Component Analysis (PCA) showed the significant positive loading of PC1 (84.71%) that influencing the dual treatments of wastewater. Statistical analysis (p ≤ 0.05) confirmed the effectiveness of agricultural biomaterials in sewage water treatment compared to pre−treated water. The turbidity coagulation pseudo−first−order and pseudo−second−order kinetic modelling also revealed the efficiency against turbidity reduction in municipal sewage water. The findings underscore the significance of utilizing agricultural waste materials for sustainable and efficient purification of municipal sewage water, addressing water pollution and enhancing wastewater treatment processes.</p

Observation of the Ξb−\Xi^-_\mathrm{b}→\toψ\psi(2S)Ξ−\Xi^- decay and studies of the Ξb∗0\Xi_\mathrm{b}^{\ast{}0} baryon in proton-proton collisions at s\sqrt{s} = 13 TeV

The first observation of the decay $\Xi^-_\mathrm{b}$$\to$$\psi$(2S)$\Xi^-$ and measurement of the branching ratio of $\Xi^-_\mathrm{b}$$\to$$\psi$(2S)$\Xi^-$ to $\Xi^-_\mathrm{b}$$\to$ J/$\psi$$\Xi^-$ are presented. The J/$\psi$ and $\psi$(2S) mesons are reconstructed using their dimuon decay modes. The results are based on proton-proton colliding beam data from the LHC collected by the CMS experiment at $\sqrt{s}$ = 13 TeV in 2016-2018, corresponding to an integrated luminosity of 140 fb$^{-1}$. The branching fraction ratio is measured to be $\mathcal{B}$($\Xi^-_\mathrm{b}$$\to$$\psi$(2S)$\Xi^-$)/$\mathcal{B}$($\Xi^-_\mathrm{b}$$\to$ J/$\psi$$\Xi^-$) = 0.84$^{+0.21}_{-0.19}$ (stat) $\pm$ 0.10 (syst) $\pm$ 0.02 ($\mathcal{B}$), where the last uncertainty comes from the uncertainties in the branching fractions of the charmonium states. New measurements of the $\Xi_\mathrm{b}^{\ast{}0}$ baryon mass and natural width are also presented, using the $\Xi_\mathrm{b}^-\pi^+$ final state, where the $\Xi^-_\mathrm{b}$ baryon is reconstructed through the decays J/$\psi \Xi^-$, $\psi$(2S)$\Xi^-$, J/$\psi \Lambda$K$^-$, and J/$\psi \Sigma^0$K$^-$. Finally, the fraction of the $\Xi^-_\mathrm{b}$ baryons produced from $\Xi_\mathrm{b}^{\ast{}0}$ decays is determined

Search for heavy neutral leptons in final states with electrons, muons, and hadronically decaying tau leptons in proton-proton collisions at s \sqrt{s} = 13 TeV

A search for heavy neutral leptons (HNLs) of Majorana or Dirac type using proton-proton collision data at $\sqrt{s}$ = 13 TeV is presented. The data were collected by the CMS experiment at the CERN LHC and correspond to an integrated luminosity of 138 fb$^{−1}$. Events with three charged leptons (electrons, muons, and hadronically decaying tau leptons) are selected, corresponding to HNL production in association with a charged lepton and decay of the HNL to two charged leptons and a standard model (SM) neutrino. The search is performed for HNL masses between 10 GeV and 1.5 TeV. No evidence for an HNL signal is observed in data. Upper limits at 95% confidence level are found for the squared coupling strength of the HNL to SM neutrinos, considering exclusive coupling of the HNL to a single SM neutrino generation, for both Majorana and Dirac HNLs. The limits exceed previously achieved experimental constraints for a wide range of HNL masses, and the limits on tau neutrino coupling scenarios with HNL masses above the W boson mass are presented for the first time.[graphic not available: see fulltext

Search for pair production of scalar and vector leptoquarks decaying to muons and bottom quarks in proton-proton collisions at s\sqrt{s} = 13 TeV

International audienceA search for pair production of scalar and vector leptoquarks (LQs) each decaying to a muon and a bottom quark is performed using proton-proton collision data collected at $\sqrt{s}$ = 13 TeV with the CMS detector at the CERN LHC, corresponding to an integrated luminosity of 138 fb$^{-1}$. No excess above standard model expectation is observed. Scalar (vector) LQs with masses less than 1810 (2120) GeV are excluded at 95% confidence level, assuming a 100% branching fraction of the LQ decaying to a muon and a bottom quark. These limits represent the most stringent to date

Search for long-lived particles using displaced vertices and missing transverse momentum in proton-proton collisions at s\sqrt{s} = 13 TeV

A search for the production of long-lived particles in proton-proton collisions at a center-of-mass energy of 13 TeV at the CERN LHC is presented. The search is based on data collected by the CMS experiment in 2016-2018, corresponding to a total integrated luminosity of 137 fb$^{-1}$. This search is designed to be sensitive to long-lived particles with mean proper decay lengths between 0.1 and 1000 $\mu$m, whose decay products produce a final state with at least one displaced vertex and missing transverse momentum. A machine learning algorithm, which improves the background rejection power by more than an order of magnitude, is applied to improve the sensitivity. The observation is consistent with the standard model background prediction, and the results are used to constrain split supersymmetry (SUSY) and gauge-mediated SUSY breaking models with different gluino mean proper decay lengths and masses. This search is the first CMS search that shows sensitivity to hadronically decaying long-lived particles from signals with mass differences between the gluino and neutralino below 100 GeV. It sets the most stringent limits to date for split-SUSY models and gauge-mediated SUSY breaking models with gluino proper decay length less than 6 $\mu$m