Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

Nationalism and racial Hellenism in nineteenth‐century England and France

This article assesses the part played by physical anthropology and classical archaeology in the transformation of nineteenth‐century English and French nationalisms into racial Hellenisms. At that time the anthropological ideas of race and racial determinism introduced the body into conceptions of national identity and community. Physical anthropologists placed the Greek body at the centre of their studies, claiming, first, that the Greek physique, and particularly that of the ancient Greek athlete, recorded in the newly discovered Pheidian and Polycletan sculpture, was biologically perfect; second, that the perfection of the Greek athlete was due to race, in the sense of biological inheritance, as well as to athletics; third, that in accordance with the theory of racial determinism, ancient Greek civilization and political power were due to the peculiarities of Greek biology; and fourth, that the Greek body was the type of all other European nations in their fullest physical development. The nationalism and positivism of nineteenth‐century European thought led European nations to accept these ideas and to claim a Greek physical and cultural identity. The belief that all Europeans were Greek had important practical consequences for English and French life, prompting an emphasis on the care for the body through open‐air exercises in imitation of the Greeks, and producing a new classical revival on a national scale. However, although physical anthropology was a European discipline, national peculiarities and rivalries produced variations both in the timing and in the form of English and French Hellenisms