Combinatorics of Hard Particles on Planar Graphs

We revisit the problem of hard particles on planar random tetravalent graphs in view of recent combinatorial techniques relating planar diagrams to decorated trees. We show how to recover the two-matrix model solution to this problem in this purely combinatorial language.Comment: 35 pages, 20 figures, tex, harvmac, eps

Trace anomaly of the conformal gauge field

The proposed by Bastianelli and van Nieuwenhuizen new method of calculations of trace anomalies is applied in the conformal gauge field case. The result is then reproduced by the heat equation method. An error in previous calculation is corrected. It is pointed out that the introducing gauge symmetries into a given system by a field-enlarging transformation can result in unexpected quantum effects even for trivial configurations.Comment: 9 pages, LaTeX file, BI-TP 93/3

B006 Effects of losartan in an experimental model of metabolic syndrome

IntroductionA large body of experimental and clinical evidence indicates that some AT1 receptor antagonists may have beneficial metabolic effects in addition to their well-known cardiovascular actions. Whether or not these metabolic effects are related to additional PPARγ agonist activity of some AT1 antagonists is still under debate. Therefore, the aim of the present study was to check the cardiovascular and metabolic effects of losartan lacking any PPAR agonist activity in a suitable experimental model of metabolic syndrome, namely SHHF rats (Spontaneously Hypertensive, Heart Failure). These rats exhibit obesity, hypertension, dyslipidemia and glucose intolerance. They lack leptin receptors. WKY and SH rats were considered as control of SHHF rats.MethodsLosartan was delivered in the drinking water (10mg/kg/day during 3 months) to 12-week-old male rats. Cardiovascular and metabolic parameters were measured at the end of the treatment and compared to those of untreated SHHF rats at the same age. Intravenous glucose tolerance tests (IVGTT) were also performed. Total cholesterol, LDL, HDL, triglycerides and glucose were measured on plasma samples (0,5ml) taken from caudal veins. Blood pressure was measured (right femoral artery) under pentobarbital anaesthesia (60mg/kg, ip).Mean values±SEM are presented. P values < 0.05 were considered significant. Unpaired Student¡¦s t-tests were used for intergroup comparisons.ResultsEffects of a 3-month treatment are shown in the previous table (SHHF rats).* : p<0.05Losartan impaired significantly glucose tolerance in SHHF rats.The treatment had no significant metabolic effect in WKY and SH rats.ConclusionOur study showed that, at an antihypertensive dose, losartan impaired glucose tolerance, fasted glycaemia, plasma triglycerides and free fatty acids in SHHF rats whereas it had no significant metabolic effect in WKY and SH rats

Three osculating walkers

We consider three directed walkers on the square lattice, which move simultaneously at each tick of a clock and never cross. Their trajectories form a non-crossing configuration of walks. This configuration is said to be osculating if the walkers never share an edge, and vicious (or: non-intersecting) if they never meet. We give a closed form expression for the generating function of osculating configurations starting from prescribed points. This generating function turns out to be algebraic. We also relate the enumeration of osculating configurations with prescribed starting and ending points to the (better understood) enumeration of non-intersecting configurations. Our method is based on a step by step decomposition of osculating configurations, and on the solution of the functional equation provided by this decomposition

ARIA 2016 : Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle

European Innovation Partnership on Active and Healthy Ageing Reference Site MACVIA-France, EU Structural and Development Fund Languedoc-Roussillon, ARIA.Peer reviewedPublisher PD

The hidden burden of adult allergic rhinitis : UK healthcare resource utilisation survey

Funding Funding for this survey was provided by Meda Pharma.Peer reviewedPublisher PD