Relación entre las tecnologías para el ocio y el tiempo libre y el índice de masa corporal (IMC) en escolares de etnia gitana e inmigrantes marroquíes

La obesidad se ha convertido en la epidemia del siglo XXI (OMS). Este estudio tiene el objetivo de encontrar la prevalencia de sobrepeso u obesidad en escolares de etnia gitana e inmigrantes marroquíes y su relación con el Índice de Masa Corporal (IMC) y con las tecnologías para el ocio y el tiempo libre. Han sido analizados 130 sujetos, con edades comprendidas entre 6 y 12 años (n1= 66 niños; n2= 64 niñas) del CEIP Aníbal del barrio marginal de Los Mateos de Cartagena. El 75% de los niños83 con un IMC no saludable tiene en sus hogares una videoconsola y más del 65% no practica ningún tipo de actividad física (AF) fuera del centro

The chemical, microbiological and volatile composition of kefir-like beverages produced from red table grape juice in repeated 24-h fed-batch subcultures

The aim of this work was to study the production of kefir-like beverages via the fed-batch fermentation of red table grape juice at initial pHs of 3.99 (fermentation A) and 5.99 (fermentation B) with kefir grains during 4 repeated 24-h fed-batch subcultures. All kefir-like beverages (KLB) were characterized by low alcoholic grade (≤3.6%, v/v) and lactic and acetic acid concentrations. The beverages obtained from fermentation B had lower concentrations of sugars and higher microbial counts than the KLB obtained in fermentation A. Additionally, the KLB samples from fermentation B were the most aromatic and had the highest contents of alcohols, esters, aldehydes and organic acids, in contrast with the nonfermented juice and KLB from fermentation A. These results indicate the possibility of obtaining red table grape KLB with their own distinctive aromatic characteristics and high content in probiotic viable cells, contributing to the valorization of this fruit.Ministerio de Ciencia, Innovación y Universidades | Ref. FPU16/04077Universidad Nacional de Jaén (Perú) | Ref. 2017-I-PRONABEC—Per

Validation of quantitative flow ratio-derived virtual angioplasty with post-angioplasty fractional flow reserve—the QIMERA-I study

Producción CientíficaBackground: Quantitative flow ratio (QFR) virtual angioplasty with pre-PCI residual QFR showed better results compared with an angiographic approach to assess post-PCI functional results. However, correlation with pre-PCI residual QFR and post-PCI fractional flow reserve (FFR) is lacking. Methods: A multicenter prospective study including consecutive patients with angiographically 50–90% coronary lesions and positive QFR results. All patients were evaluated with QFR, hyperemic and non-hyperemic pressure ratios (NHPR) before and after the index PCI. Pre-PCI residual QFR (virtual angioplasty) was calculated and compared with post-PCI fractional flow reserve (FFR), QFR and NHPR. Results: A total of 84 patients with 92 treated coronary lesions were included, with a mean age of 65.5 ± 10.9 years and 59% of single vessel lesions being the left anterior descending artery in 69%. The mean vessel diameter was 2.82 ± 0.41 mm. Procedural success was achieved in all cases, with a mean number of implanted stents of 1.17 ± 0.46. The baseline QFR value was 0.69 ± 0.12 and baseline FFR and NHPR were 0.73 ± 0.08 and 0.82 ± 0.11, respectively. Mean post-PCI FFR increased to 0.87 ± 0.05 whereas residual QFR had been estimated as 0.95 ± 0.05, showing poor correlation with post-PCI FFR (0.163; 95% CI:0.078–0.386) and low diagnostic accuracy (30.9%, 95% CI:20–43%). Conclusions: In this analysis, the results of QFR-based virtual angioplasty did not seem to accurately correlate with post-PCI FFR

Everolimus plus minimized tacrolimus on kidney function in liver transplantation: REDUCE, a prospective, randomized controlled study

Background and aim: reduction in calcineurin inhibitor levels is considered crucial to decrease the incidence of kidney dysfunction in liver transplant (LT) recipients. The aim of this study was to evaluate the safety and impact of everolimus plus reduced tacrolimus (EVR + rTAC) vs. mycophenolate mofetil plus tacrolimus (MMF + TAC) on kidney function in LT recipients from Spain. Methods: the REDUCE study was a 52-week, multicenter, randomized, controlled, open-label, phase 3b study in de novo LT recipients. Eligible patients were randomized (1:1) 28 days post-transplantation to receive EVR + rTAC (TAC levels <_ 5 ng/mL) or to continue with MMF + TAC (TAC levels = 6-10 ng/mL). Mean estimated glomerular filtration rate (eGFR), clinical benefit in renal function, and safety were evaluated. Results: in the EVR + rTAC group (n = 105), eGFR increased from randomization to week 52 (82.2 [28.5] mL/min/1.73 m2 to 86.1 [27.9] mL/min/1.73 m2) whereas it decreased in the MMF + TAC (n = 106) group (88.4 [34.3] mL/min/1.73 m2 to 83.2 [25.2] mL/min/1.73 m2), with significant (p < 0.05) differences in eGFR throughout the study. However, both groups had a similar clinical benefit regarding renal function (improvement in 18.6 % vs. 19.1 %, and stabilization in 81.4 % vs. 80.9 % of patients in the EVR + rTAC vs. MMF + TAC groups, respectively). There were no significant differences in the incidence of acute rejection (5.7 % vs. 3.8 %), deaths (5.7 % vs. 2.8 %), and serious adverse events (51.9 % vs. 44.0 %) between the 2 groups. Conclusion: EVR + rTAC allows a safe reduction in tacrolimus exposure in de novo liver transplant recipients, with a significant improvement in eGFR but without significant differences in renal clinical benefit 1 year after liver transplantation

Revista de Revistas.

-Archivos de Neurobiología (enero-febrero, 1989). -Actas Luso-Españolas de Neurología, Psiquiatría y Ciencias Afines(marzo-abril, 1989, número 2, volumen XVII). -Acta Psiquiatrica Scandinavica, abril, 1989. -American Journal of Psychiatry, qbril, 1989. -British Journal ofPsychiatry, abril, 1989, volumen 154. -Hospital and Community Psychiatry, abril, 1989

Revista de Revistas.

Revisión de publicaciones de mayo de 1989 -Acta Psychiatrica Scandinavica, vol. 79, n.O 5, may, 1989. -American Journal of Psychiatry, vol. 146, n.O 5, may, 1989. -Archives of General Psychiatry, vol. 46, may, 1989. -British Journal ofPsychiatry, vol. 154, may, 1989. -Family Process, vol. 28, n.O 2, june, 1989. -Hospital and Community, vol. 40, n.O 5, may, 1989