8,082 research outputs found
A Graph-Based Approach to Address Trust and Reputation in Ubiquitous Networks
The increasing popularity of virtual computing environments such as Cloud and Grid computing is helping to drive the realization of ubiquitous and pervasive computing. However, as computing becomes more entrenched in everyday life, the concepts of trust and risk become increasingly important. In this paper, we propose a new graph-based theoretical approach to address trust and reputation in complex ubiquitous networks. We formulate trust as a function of quality of a task and time required to authenticate agent-to-agent relationship based on the Zero-Common Knowledge (ZCK) authentication scheme. This initial representation applies a graph theory concept, accompanied by a mathematical formulation of trust metrics. The approach we propose increases awareness and trustworthiness to agents based on the values estimated for each requested task, we conclude by stating our plans for future work in this area
Evolution of magnetic fields and energetics of flares in active region 8210
To better understand eruptive events in the solar corona, we combine sequences of multi-wavelength observations and modelling of the coronal magnetic field of NOAA AR 8210, a highly flare-productive active region. From the photosphere to the corona, the observations give us information about the motion of magnetic elements (photospheric magnetograms), the location of flares (e.g., H, EUV or soft X-ray brightenings), and the type of events (H blueshift events). Assuming that the evolution of the coronal magnetic field above an active region can be described by successive equilibria, we follow in time the magnetic changes of the 3D nonlinear force-free (nlff) fields reconstructed from a time series of photospheric vector magnetograms. We apply this method to AR 8210 observed on May 1, 1998 between 17:00 UT and 21:40 UT. We identify two types of horizontal photospheric motions that can drive an eruption: a clockwise rotation of the sunspot, and a fast motion of an emerging polarity. The reconstructed nlff coronal fields give us a scenario of the confined flares observed in AR 8210: the slow sunspot rotation enables the occurence of flare by a reconnection process close to a separatrix surface whereas the fast motion is associated with small-scale reconnections but no detectable flaring activity. We also study the injection rates of magnetic energy, Poynting flux and relative magnetic helicity through the photosphere and into the corona. The injection of magnetic energy by transverse photospheric motions is found to be correlated with the storage of energy in the corona and then the release by flaring activity. The magnetic helicity derived from the magnetic field and the vector potential of the nlff configuration is computed in the coronal volume. The magnetic helicity evolution shows that AR 8210 is dominated by the mutual helicity between the closed and potential fields and not by the self helicity of the closed field which characterizes the twist of confined flux bundles. We conclude that for AR 8210 the complex topology is a more important factor than the twist in the eruption process
Holographic perfect fluidity, Cotton energy-momentum duality and transport properties
We investigate background metrics for 2+1-dimensional holographic theories
where the equilibrium solution behaves as a perfect fluid, and admits thus a
thermodynamic description. We introduce stationary perfect-Cotton geometries,
where the Cotton--York tensor takes the form of the energy--momentum tensor of
a perfect fluid, i.e. they are of Petrov type D_t. Fluids in equilibrium in
such boundary geometries have non-trivial vorticity. The corresponding bulk can
be exactly reconstructed to obtain 3+1-dimensional stationary black-hole
solutions with no naked singularities for appropriate values of the black-hole
mass. It follows that an infinite number of transport coefficients vanish for
holographic fluids. Our results imply an intimate relationship between
black-hole uniqueness and holographic perfect equilibrium. They also point
towards a Cotton/energy--momentum tensor duality constraining the fluid
vorticity, as an intriguing boundary manifestation of the bulk mass/nut
duality.Comment: V3: 1+39 pages, JHEP versio
The clinical significance of urinary tract infection and Asymptomatic Bacteriuria in Type 2 Diabetes Mellitus patients in the general practices of Varna region - Bulgaria
Background: The urinary system of diabetics is one of their most frequently affected body systems. Periodic urine analysis reveals that asymptomatic bacteriuria is very often detected in this population. Objectives: The aim of the study is to estimate the clinical significance of upper urinary tract infection (UUT/) and asymptomatic bacteriuria (ABU) in diabetics in a general practice setting, their clinical characteristics, incidence, course, evolution and complications. Methods: We tested 560 patients with type 2 diabetes mellitus (DM) from 12 general practices ofVarna region, Bulgaria in a prospective study. We traced ABU in the group for 2 years. There were 310 female patients (55.4%) mean age 52.5 ± 3.2 years and duration of DM was 8.5 ± 2.8 years. Results: The results showed that in 11.14% ABU was significant. Only 4.82% of diabetics developed upper urinary tract infection and the complications from it were very rare: 0.89% pyonephrosis and 0.89% sepsis. Conclusions: Our conclusion was that upper urinary tract infection in diabetics was not as severe as reported in the literature. Pyelonephritis had a benign course and only 16.6% of our patients developed chronic renal failure a few years later but the reason for its development was not diabetic nephropathy. All these facts show that ABU disappears spontaneously in most diabetics. Relevance to general practice: We discuss the question: is it necessary for every case of ABU in diabetics in general practice to be treated and isn't it time to revaluate the postulated antibiotic treatment for diabetics with ABU?peer-reviewe
Preimplantation biopsy predicts delayed graft function, glomerular filtration rate and long-term graft survival of transplanted kidneys
Background
The predictive value of preimplantation biopsies for long-term graft function is often limited by conflicting results. The aim of this study was to evaluate the influence of time-zero graft biopsy histological scores on early and late graft function, graft survival and patient survival, at different time points.
Methods
We retrospectively analyzed 284 preimplantation biopsies at a single center, in a cohort of recipients with grafts from live and deceased donors (standard and nonstandard), and their impact in posttransplant renal function after a mean follow-up of 7 years (range 1–16). Implantation biopsy score (IBS), a combination score derived from 4 histopathological aspects, was determined from each sample. The correlation with incidence of delayed graft function (DGF), creatinine clearance (1st, 3rd and 5th posttransplant year) and graft and patient survival at 1 and 5 years were evaluated.
Results
Preimplantation biopsies provided somewhat of a prognostic index of early function and outcome of the transplanted kidney in the short and long term. In the immediate posttransplantation period, the degree of arteriolosclerosis and interstitial fibrosis correlated better with the presence of DGF. IBS values between 4 and 6 were predictive of worst renal function at 1st and 3rd years posttransplant and 5-year graft survival. The most important histological finding, in effectively transplanted grafts, was the grade of interstitial fibrosis. Patient survival was not influenced by IBS.
Conclusions
Higher preimplantation biopsy scores predicted an increased risk of early graft losses, especially primary nonfunction. Graft survival (at 1st and 5th years after transplant) but not patient survival was predicted by IBS
The quantum-classical transition in thermally seeded parametric downconversion
We address the pair of conjugated field modes obtained from
parametric-downconversion as a convenient system to analyze the
quantum-classical transition in the continuous variable regime. We explicitly
evaluate intensity correlations, negativity and entanglement for the system in
a thermal state and show that a hierarchy of nonclassicality thresholds
naturally emerges in terms of thermal and downconversion photon number. We show
that the transition from quantum to classical regime may be tuned by
controlling the intensities of the seeds and detected by intensity
measurements. Besides, we show that the thresholds are not affected by losses,
which only modify the amount of nonclassicality. The multimode case is also
analyzed in some detail.Comment: 12 pages, 3 figure
The quantum-classical transition in thermally seeded parametric downconversion
We address the pair of conjugated field modes obtained from
parametric-downconversion as a convenient system to analyze the
quantum-classical transition in the continuous variable regime. We explicitly
evaluate intensity correlations, negativity and entanglement for the system in
a thermal state and show that a hierarchy of nonclassicality thresholds
naturally emerges in terms of thermal and downconversion photon number. We show
that the transition from quantum to classical regime may be tuned by
controlling the intensities of the seeds and detected by intensity
measurements. Besides, we show that the thresholds are not affected by losses,
which only modify the amount of nonclassicality. The multimode case is also
analyzed in some detail.Comment: 12 pages, 3 figure
Using the standard THC unit to regulate THC content in legal cannabis markets [Commentary]
Abstract not available
'Standard THC Units':a proposal to standardise dose across all cannabis products and methods of administration
BACKGROUND: Cannabis products are becoming increasingly diverse, and they vary considerably in concentrations of ∆9 -tetrahydrocannabinol (THC) and cannabidiol (CBD). Higher doses of THC can increase the risk of harm from cannabis, while CBD may partially offset some of these effects. Lower Risk Cannabis Use Guidelines currently lack recommendations based on quantity of use, and could be improved by implementing standard units. However, there is currently no consensus on how units should be measured or standardised across different cannabis products or methods of administration.ARGUMENT: Existing proposals for standard cannabis units have been based on specific methods of administration (e.g. joints) and these may not capture other methods including pipes, bongs, blunts, dabbing, vaporizers, vape pens, edibles and liquids. Other proposals (e.g. grams of cannabis) cannot account for heterogeneity in THC concentrations across different cannabis products. Similar to alcohol units, we argue that standard cannabis units should reflect the quantity of active pharmacological constituents (dose of THC). On the basis of experimental and ecological data, public health considerations, and existing policy we propose that a 'Standard THC Unit' should be fixed at 5 milligrams of THC for all cannabis products and methods of administration. If supported by sufficient evidence in future, consumption of Standard CBD Units might offer an additional strategy for harm reduction.CONCLUSIONS: Standard THC Units can potentially be applied across all cannabis products and methods of administration to guide consumers and promote safer patterns of use.</p
'Standard THC Units':a proposal to standardise dose across all cannabis products and methods of administration
Background and Aims
Cannabis products are becoming increasingly diverse, and vary considerably in concentrations of ∆9-tetrahydrocannabinol (THC) and cannabidiol (CBD). Higher doses of THC can increase the risk of harm from cannabis, while CBD may partially offset some of these effects. Lower Risk Cannabis Use Guidelines currently lack recommendations based on quantity of use, and could be improved by implementing standard units. However, there is currently no consensus on how units should be measured or standardized among different cannabis products or methods of administration.
Argument
Existing proposals for standard cannabis units have been based on specific methods of administration (e.g. joints) and these may not capture other methods, including pipes, bongs, blunts, dabbing, vaporizers, vape pens, edibles and liquids. Other proposals (e.g. grams of cannabis) cannot account for heterogeneity in THC concentrations among different cannabis products. Similar to alcohol units, we argue that standard cannabis units should reflect the quantity of primary active pharmacological constituents (dose of THC). On the basis of experimental and ecological data, public health considerations and existing policy, we propose that a ‘standard THC unit’ should be fixed at 5 mg THC for all cannabis products and methods of administration. If supported by sufficient evidence in future, consumption of standard CBD units might offer an additional strategy for harm reduction.
Conclusions
Standard ∆9-tetrahydrocannabinol (THC) units can potentially be applied among all cannabis products and methods of administration to guide consumers and promote safer patterns of use
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