437 research outputs found
Katedra Nauki Administracji i Prawa Administracyjnego Wydziału Prawno-Ekonomicznego Uniwersytetu Poznańskiego w okresie dwudziestolecia międzywojennego. Organizacja i główne kierunki badawczo-dydaktyczne
The aim of the article is to analyse source materials related to the functioning of the Chair of Administration Science and Administrative Law at the University of Poznań. The study discusses the problems experienced by the then-contemporary scientific and lecturing staff, and also characterised the atypical structure of the Faculty of Law and Economics, as composed of the sections of state law and economy. The organization of the chairs of administrative law at the University of Poznań was separated and their main research and development directions and the most important representatives were indicated. The article broadly discusses the issue of teaching administrative law in comparison to other chairs of the University of Poznań, so that the conclusions give the best possible image of the discussed subject.Celem artykułu jest analiza materiałów źródłowych związanych z funkcjonowaniem Katedry Nauki Administracji i Prawa Administracyjnego na Uniwersytecie Poznańskim. W opracowaniu omówiono problemy, z jakimi borykali się ówcześni pracownicy naukowo-dydaktyczni, scharakteryzowano także nietypową strukturę Wydziału Prawno-Ekonomicznego. Wyodrębniono organizację katedr prawa administracyjnego funkcjonujących na Uniwersytecie Poznańskim oraz wskazano ich główne kierunki badawczo-rozwojowe i najważniejszych przedstawicieli. W pracy szeroko umiejscowiona została pozycja nauczania prawa administracyjnego na tle innych katedr Uniwersytetu Poznańskiego, tak aby końcowe wnioski dały najlepszy obraz istoty omawianego przedmiotu
Penile fracture with urethral rupture - case report
Introduction
Penile fracture is a rupture of the tunica albuginea of the corpus cavernosum caused by an erect penis injury. It is noticed that hematomas always accompany penile fractures. We present a rare case of penile fracture between corpus cavernosus and urethra without hematoma formation.
Case Presentation:
A 41-year-old male patient presented to the emergency department due to a continuous flow of blood from his urethra, which started an hour earlier due to a penile injury during vigorous sexual intercourse. There was no audible 'snap' sound, but the incident was followed by severe pain and immediate loss of tumescence. His bleeding continued until surgery. No hematoma was observed – Figure 1. A urethrography was performed, and afterward, an experienced urologist inserted a catheter without encountering any resistance. The patient was diagnosed with rupturing the tunica albuginea of the corpus cavernosum and the urethra. No hematoma was found, and primary revision was performed. Urethra and tunica albuginea was sutured. After four weeks catheter was removed. The patient recovered with good uroflowmetry results and did not report erectile dysfunction.
Conclusions
Rapture of tunica albuginea to the urethra may cause severe bleeding without formation of the hematoma and "eggplant deformity." Therefore, early intervention is crucial to sustain erectile function and avoid urethral stricture
Review of commercially available biomarkers in the diagnosis of prostate cancer
Introduction
Diagnosing prostate cancer is a complex process. Although PSA testing remains the basic laboratory study, new biomarkers and test are evolving quickly.
Aim
The aim of this review was to summarize available tests and markers for diagnosing prostate cancer.
Materials and methods
Literature search was conducted using PubMed and Cohrane databases.
Results and conclusions
Detailed description of ExoDx, PCA3, SelectMDx, Mi-prostate Score, SChLAP1, PSA, PHI, 4K Score tests was presented. Available test ease qualification for a prostate biopsy or observation. Patients should be qualified individually in deciding on a specific test to be performed. Urologists should be aware of each test mechanism and limitations.
Consideration of Critical Parameters for Improving the Efficiency of Concrete Structures Reinforced with FRP
Funding Information: This research was supported by the Polish National Agency for Academic Exchange no.: PPN/IWA/2019/1/00155/U/00001 (Iwanowska programme). Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.Fibre-reinforced polymer materials (FRP) are increasingly used to reinforce structural elements. Due to this, it is possible to increase the load-bearing capacity of polymer, wooden, concrete, and metal structures. In this article, the authors collected all the crucial aspects that influence the behaviour of concrete elements reinforced with FRP. The main types of FRP, their characterization, and their impact on the load-carrying capacity of a composite structure are discussed. The most significant aspects, such as type, number of FRP layers including fibre orientation, type of matrix, reinforcement of concrete columns, preparation of a concrete surface, fire-resistance aspects, recommended conditions for the lamination process, FRP laying methods, and design aspects were considered. Attention and special emphasis were focused on the description of the current research results related to various types of concrete reinforced with FRP composites. To understand which aspects should be taken into account when designing concrete reinforcement with composite materials, the main guidelines are presented in tabular form.publishersversionpublishe
Polymorphic members of the lag gene family mediate kin discrimination in Dictyostelium
Self and kin discrimination are observed in most kingdoms of life and are mediated by highly polymorphic plasma membrane proteins. Sequence polymorphism, which is essential for effective recognition, is maintained by balancing selection. Dictyostelium discoideum are social amoebas that propagate as unicellular organisms but aggregate upon starvation and form fruiting bodies with viable spores and dead stalk cells. Aggregative development exposes Dictyostelium to the perils of chimerism, including cheating, which raises questions about how the victims survive in nature and how social cooperation persists. Dictyostelids can minimize the cost of chimerism by preferential cooperation with kin, but the mechanisms of kin discrimination are largely unknown. Dictyostelium lag genes encode transmembrane proteins with multiple immunoglobulin (Ig) repeats that participate in cell adhesion and signaling. Here, we describe their role in kin discrimination. We show that lagB1 and lagC1 are highly polymorphic in natural populations and that their sequence dissimilarity correlates well with wild-strain segregation. Deleting lagB1 and lagC1 results in strain segregation in chimeras with wild-type cells, whereas elimination of the nearly invariant homolog lagD1 has no such consequences. These findings reveal an early evolutionary origin of kin discrimination and provide insight into the mechanism of social recognition and immunity
Digitizing Historical Aerial Images: Evaluation of the Effects of Scanning Quality on Aerial Triangulation and Dense Image Matching
In the last decade, many aerial photographic archives have started to be digitized for multiple purposes, including digital preservation and geoprocessing. This paper analyzes the effects of professional photogrammetric versus consumer-grade scanners on the processing of analog historical aerial photographs. An image block over Warsaw is considered, featuring 38 photographs acquired in 1986 (Wild RC10, Normal Aviogon II lens, 23 × 23 cm format) with a ground sampling distance (GSD) of 4 cm. Aerial triangulation (AT) and dense image matching (DIM) procedures are considered, analyzing how scanning modalities are important in the massive digitization of analog images for georeferencing and 3D product generation. The achieved results show how consumer-grade scanners, unlike more expensive photogrammetric scanners, do not possess adequate recording quality to ensure high accuracy and geometric precision for geoprocessing purposes. However, consumer-grade scanners can be used for time and cost-efficient applications where a partial loss of data quality is not critical
Severe calcification of forgotten Double-J ureteral stent in a patient with undiagnosed hyperparathyroidism
Background
Double J stent (DJ) is widely used in urological practice in patients with renal stones. However, its application is related to the risk of incrustation. We present a case of severe calcification of forgotten DJ in a patient with previously undiagnosed hyperparathyroidism (HPT).
Case presentation
A 30-year-old female was admitted to the Urology Department with renal colic. An initial kidney, ureter, and bladder X-ray revealed a completely calcified DJ catheter placed twelve months earlier. Unfortunately, the patient did not show up for a follow-up visit, and stent removal was not performed. Due to the extent of the disease, the patient was qualified for multistage endoscopic treatment. Total treatment lasted six months and consisted of five urereroscopies and one hybrid procedure. Simultaneously, diagnostics of a metabolic cause of the advanced stone disease suggested primary hyperparathyroidism, confirmed during parathyroid scintigraphy. After urological treatment had been completed, parathyroidectomy was performed. During a further 7-year follow-up, only one episode of renal colic occurred within the first year after treatment. The patient is stone-free until the present day.
Conclusions
Stents are designed to last usually up to six months, but they should be removed as quickly as possible after finishing treatment. Also, other causes such as a metabolic or hormonal imbalance should be considered. In our patient combination of forgotten DJ and HPT was the reason for excessive stone formation. Selective removal of the parathyroid gland was effective in the presented patient, with no stone recurrence observed
Prevalence of electrocardiographic left ventricular hypertrophy among patients with coronary artery disease and diabetes mellitus
Introduction. Electrocardiography (ECG) is a widely used non-invasive diagnostic method for assessment of patients with cardiovascular diseases. Numerous different electrocardiographic criteria exist for detection of left ventricular hypertrophy (LVH). LVH is an important risk factor in patients with coronary artery disease (CAD) or diabetes mellitus and its presence is associated with increased cardiovascular morbidity and mortality. The aim of this study was to evaluate the prevalence of the most frequently used electrocardiographic left ventricular hypertrophy (ECG-LVH) criteria among patients with CAD and diabetes.
Methods. A cross-sectional, multicenter study was conducted in outpatient clinics across Poland. Family physicians performed physical examinations and collected relevant information about: onset of CAD and diabetes, presence and onset of hypertension, dyslipidemia, heart failure, diabetic complications, history of acute coronary syndrome and pharmacotherapy. In order to detect LVH, we used seven ECG criteria: 1) the Sokolow-Lyon voltage, 2) the Gubner voltage, 3) the criterion of the R wave amplitude on the leads V5–V6 and 4) aVL, 5) the gender specific Cornell voltage and 6) product, and 7) the Romhilt-Estes point score. Centralized manual assessment of the obtained ECG tracings were performed.
Results. We enrolled 1001 patients (48.5% women, 51.5% men, mean age 65 ± 11 years) into the study. At least one ECG-LVH criterion was met in 20.0% (n = 200) of the study participants. The ECG-LVH diagnosis was the most common when using the Romhilt-Estes point score (n = 138; 13.8%). The corresponding prevalence rates for the Cornell voltage, the Cornell product, the R wave amplitude on the lead aVL, the Sokolow-Lyon voltage, the Gubner voltage and the R wave amplitude on the leads V5-V6 criteria were 5.5% (n = 55), 5.2% (n = 52), 3.2% (n = 32), 2.2% (n = 22), 1.9% (n = 19) and 1.3% (n = 13) respectively. Subsequently, the prevalence of the three most frequently used in clinical practice electrocardiographic criteria for LVH (the Sokolow-Lyon voltage, the Cornell voltage and the Romhilt-Estes point score) was analyzed. At least one of them was fulfilled in 185 ECGs. All three criteria at the same time were met only in 5 ECGs (2.7% of 185). Two and only one out of three criteria were fulfilled in 20 (10.8%) and 160 (86.5%) ECGs respectively.
Conclusions. The co-occurrence of all assessed ECG-LVH criteria, including the three most frequently applied in clinical practice, is very low in diabetic CAD patients. The Romhilt-Estes point score identifies the highest number of ECG-LVH cases in this setting. However, it seems reasonable to use routinely several ECG criteria for detection of LVH. Further studies are needed to compare diagnostic values of ECG-LVH criteria with imaging methods and to assess prognostic values of various ECG-LVH criteria
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