The development of professional skills of the recent graduates of medical sciences

Introduction: the professionalization of the recent graduate is one of the priorities, given the need of improving the ways of performance for competent professional graduates.   Objective: describe the ways for a competent performance of the new professionals of Medical Sciences.   Method: the dialectical materialist method was used, which allowed to analyze the contradictions in the process of professionalization of the recent graduates, aimed at determining the relationships and dependencies between the elements involved in this process in the field of research, and the trends of the development, through a documentary review, and surveys applied to the new physicians, as well as interviews with employers.   Development: the professionalization of the medical graduates is conditioned by the quality, integrality and pertinence during the continuous training, a stage that is marked by decisive guidelines to form an attitude before the profession and to develop the bases of his or her performance, where the first stage of the permanent training will coincide with the goal of the advanced education: "to achieve a professional who transmits and transforms the society with efficiency and quality, feeling fully satisfied with the individual emotional, moral and spiritual state."   Conclusions: the process of professionalization of the new graduate of the medical sciences is a necessity for the professional training. This process must be consolidated based on the development of competent professional activities, which means to recognize the work towards the appropriation of methods of performance as a main axis in the training process

El desarrollo de los modos de actuación profesional competentes en recién graduados de Ciencias Médicas

 Introduction: the professionalization of the recent graduate is one of the priorities, given the need of improving the ways of performance for competent professional graduates. Objective: describe the ways for a competent performance of the new professionals of Medical Sciences. Method: the dialectical materialist method was used, which allowed to analyze the contradictions in the process of professionalization of the recent graduates, aimed at determining the relationships and dependencies between the elements involved in this process in the field of research, and the trends of the development, through a documentary review, and surveys applied to the new physicians, as well as interviews with employers. Development: the professionalization of the medical graduates is conditioned by the quality, integrality and pertinence during the continuous training, a stage that is marked by decisive guidelines to form an attitude before the profession and to develop the bases of his or her performance, where the first stage of the permanent training will coincide with the goal of the advanced education: "to achieve a professional who transmits and transforms the society with efficiency and quality, feeling fully satisfied with the individual emotional, moral and spiritual state." Conclusions: the process of professionalization of the new graduate of the medical sciences is a necessity for the professional training. This process must be consolidated based on the development of competent professional activities, which means to recognize the work towards the appropriation of methods of performance as a main axis in the training process.  Introducción: la profesionalización del recién graduado es una de las prioridades de la actualidad dada la necesidad de perfeccionar los modos de actuación profesional competente de sus egresados.Objetivo: exponer los modos de actuación profesional competente en recién graduados de Ciencias Médicas.Método: se utilizó el método dialéctico materialista, que permitió analizar las contradicciones en el proceso de profesionalización del recién graduado, determinar las relaciones y dependencias entre los elementos que intervienen en este proceso en el campo de la investigación y las tendencias de su desarrollo, mediante la revisión documental, encuestas a médicos recién graduados, así como entrevistas a empleadores. Desarrollo: la profesionalización del egresado de las ciencias médicas está condicionada por la calidad, integralidad y pertinencia durante la formación continua, etapa que marca pautas decisivas para formar una actitud ante la profesión y desarrollar las bases del desempeño, siendo la primera etapa de la formación permanente y coincidiendo con el fin de la educación de avanzada: "lograr un hombre que aporte y transforme socialmente con más eficiencia y calidad, y que en lo individual esté plenamente satisfecho con su estado emocional, moral y espiritual".Conclusiones: el proceso de profesionalización del recién graduado de las ciencias médicas es una necesidad de la formación profesional. Se debe consolidar este proceso sustentado en el desarrollo de los modos de actuación profesional competente, lo que significa reconocer el trabajo hacia la apropiación de métodos de trabajo como eje transversal en su proceso de formación.

Proteomic profiling of quality protein Maize kernels using mass spectrometry

Maize (Zea mays L.) is the third most crucial crop worldwide and is of paramount importance in both humansand livestock diets. Conventional maize varieties have less than half of the amino acids recommended for humannutrition, and this deficiency results in an imbalance of amino acids and low protein content, which has been associatedwith several pathologies, including malnutrition. Thus, different countries have focused on research onfortified foods, such as quality protein maize (QPM) noting that these improved varieties may contain up to 100%more essential amino acids residues than conventional maize. Hence, this study aimed to characterize throughtandem mass spectrometry and bioinformatics analysis, relative expression of polypeptides contained in a hybridvariety of QPM, which allow to identify potential markers with implications in the management and improvementof this crops maintaining their intrinsic characteristics. We identify 262 polypeptides, highlighting those related tomolecular function (catalytic activity, structural molecule activity, and binding) and biological process (cellular andmetabolic process). These results provide the necessary information, not only for the characterization of the QPMproteome through novel tools such as proteomics, but also to describe mechanisms related to different biologicalprocesses such as the embryogenesis, development and growth of grains and eventually plants. PotentiallyIt promotes the discovery of molecular markers (biomarkers) that would allow the improvement of agronomicalprocesses

Initiatives and facilities for E&T in the nuclear science and technology master at UPM

The present Master/Doctorate in Nuclear Science and Technology programme implemented in the Department of Nuclear Engineering of the Universidad Politécnica de Madrid (NED-UPM) has the excellence qualification by the Spanish Ministry of Education. One of the main of this programme is the training for the development of methodologies of simulation, design and advanced analysis, including experimental tools, necessary in research and in professional work in the nuclear field

The STRIP instrument of the Large Scale Polarization Explorer: microwave eyes to map the Galactic polarized foregrounds

In this paper we discuss the latest developments of the STRIP instrument of the "Large Scale Polarization Explorer" (LSPE) experiment. LSPE is a novel project that combines ground-based (STRIP) and balloon-borne (SWIPE) polarization measurements of the microwave sky on large angular scales to attempt a detection of the "B-modes" of the Cosmic Microwave Background polarization. STRIP will observe approximately 25% of the Northern sky from the "Observatorio del Teide" in Tenerife, using an array of forty-nine coherent polarimeters at 43 GHz, coupled to a 1.5 m fully rotating crossed-Dragone telescope. A second frequency channel with six-elements at 95 GHz will be exploited as an atmospheric monitor. At present, most of the hardware of the STRIP instrument has been developed and tested at sub-system level. System-level characterization, starting in July 2018, will lead STRIP to be shipped and installed at the observation site within the end of the year. The on-site verification and calibration of the whole instrument will prepare STRIP for a 2-years campaign for the observation of the CMB polarization.Comment: 17 pages, 15 figures, proceedings of the SPIE Astronomical Telescopes + Instrumentation conference "Millimeter, Submillimeter, and Far-Infrared Detectors and Instrumentation for Astronomy IX", on June 15th, 2018, Austin (TX

Three-dimensional reconstruction of a recombinant influenza virus ribonucleoprotein particle

5 pages, 3 figures.-- PMID: 11306552 [PubMed].-- PMCID: PMC1083860.-- Full text available Open Access via PubMed Central:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=11306552A three-dimensional structural model of an influenza virus ribonucleoprotein particle reconstituted in vivo from recombinant proteins and a model genomic vRNA has been generated by electron microscopy. It shows a circular shape and contains nine nucleoprotein monomers, two of which are connected with the polymerase complex. The nucleoprotein monomers show a curvature that may be responsible for the formation of helical structures in the full-size viral ribonucleoproteins. The monomers show distinct contact boundaries at the two sides of the particle, suggesting that the genomic RNA may be located in association with the nucleoprotein at the base of the ribonucleoprotein complex. Sections of the three-dimensional model show a trilobular morphology in the polymerase complex that is consistent with the presence of its three subunits.J. Ortega is a fellow of the Instituto de Estudios Turolenses. E.A. is a fellow of the Comunidad de Madrid. This work was supported by the Programa Sectorial de Promoción Central del Conocimiento (grants PB97-1160 and PB96-0818).Peer reviewe

Inherited human ezrin deficiency impairs adaptive immunity

Inborn errors of immunity (IEI) are a group of monogenic diseases that confer susceptibility to infection, autoimmunity, and cancer. Despite the life-threatening consequences of some IEI, their genetic cause remains unknown in many patients. Objective: We investigated a patient with an IEI of unknown genetic etiology. Whole-exome sequencing identified a homozygous missense mutation of the gene encoding ezrin (EZR), substituting a threonine for an alanine at position 129. Ezrin is one of the subunits of the ezrin, radixin, and moesin (ERM) complex. The ERM complex links the plasma membrane to the cytoskeleton and is crucial for the assembly of an efficient immune response. The A129T mutation abolishes basal phosphorylation and decreases calcium signaling, leading to complete loss of function. Consistent with the pleiotropic function of ezrin in myriad immune cells, multidimensional immunophenotyping by mass and flow cytometry revealed that in addition to hypogammaglobulinemia, the patient had low frequencies of switched memory B cells, CD4 + and CD8 + T cells, MAIT, γδ T cells, and central naive CD4 + cells. Autosomal-recessive human ezrin deficiency is a newly recognized genetic cause of B-cell deficiency affecting cellular and humoral immunity