Behavioural Risk Factors in Mid-Life Associated with Successful Ageing, Disability, Dementia and Frailty in Later Life: A Rapid Systematic Review.

BACKGROUND: Smoking, alcohol consumption, poor diet and low levels of physical activity significantly contribute to the burden of illness in developed countries. Whilst the links between specific and multiple risk behaviours and individual chronic conditions are well documented, the impact of these behaviours in mid-life across a range of later life outcomes has yet to be comprehensively assessed. This review aimed to provide an overview of behavioural risk factors in mid-life that are associated with successful ageing and the primary prevention or delay of disability, dementia, frailty and non-communicable chronic conditions. METHODS: A literature search was conducted to identify cohort studies published in English since 2000 up to Dec 2014. Multivariate analyses and a minimum follow-up of five years were required for inclusion. Two reviewers screened titles, abstracts and papers independently. Studies were assessed for quality. Evidence was synthesised by mid-life behavioural risk for a range of late life outcomes. FINDINGS: This search located 10,338 individual references, of which 164 are included in this review. Follow-up data ranged from five years to 36 years. Outcomes include dementia, frailty, disability and cardiovascular disease. There is consistent evidence of beneficial associations between mid-life physical activity, healthy ageing and disease outcomes. Across all populations studied there is consistent evidence that mid-life smoking has a detrimental effect on health. Evidence specific to alcohol consumption was mixed. Limited, but supportive, evidence was available relating specifically to mid-life diet, leisure and social activities or health inequalities. CONCLUSIONS: There is consistent evidence of associations between mid-life behaviours and a range of late life outcomes. The promotion of physical activity, healthy diet and smoking cessation in all mid-life populations should be encouraged for successful ageing and the prevention of disability and chronic disease.This work was funded by the National Institute for Health and Care Excellence (NICE), invitation to tender reference DDER 42013, and supported by the National Institute for Health Research School for Public Health Research. The scope of the work was defined by NICE and the protocol was agreed with NICE prior to the start of work. The funders had no role in data analysis, preparation of the manuscript or decision to publish.This is the final version of the article. It first appeared from PLOS via http://dx.doi.org/10.1371/journal.pone.014440

The James Webb Space Telescope Mission

Twenty-six years ago a small committee report, building on earlier studies, expounded a compelling and poetic vision for the future of astronomy, calling for an infrared-optimized space telescope with an aperture of at least $4m$. With the support of their governments in the US, Europe, and Canada, 20,000 people realized that vision as the $6.5m$ James Webb Space Telescope. A generation of astronomers will celebrate their accomplishments for the life of the mission, potentially as long as 20 years, and beyond. This report and the scientific discoveries that follow are extended thank-you notes to the 20,000 team members. The telescope is working perfectly, with much better image quality than expected. In this and accompanying papers, we give a brief history, describe the observatory, outline its objectives and current observing program, and discuss the inventions and people who made it possible. We cite detailed reports on the design and the measured performance on orbit.Comment: Accepted by PASP for the special issue on The James Webb Space Telescope Overview, 29 pages, 4 figure

Correlates of Weight Bias in Adults From the NutriNet-Santé Study

International audienceIntroduction: Explicit weight bias (EWB) is an underlying cause of weight stigma but its associations with individual characteristics are not well known. This study aimed to assess EWB in French adults and to explore associations with weight status and sociodemographic characteristics. Methods: Adults from the NutriNet-Santé cross-sectional study (France, 2020, n=33948, 52% women after weighting procedures) completed the Anti-Fat Attitudes Questionnaire assessing three dimensions: Dislike (antipathy towards people with obesity), Fear of fat (concerns about body weight) and Willpower (belief in weight controllability). Associations with weight status and sociodemographic characteristics were examined using multi-variable ANCOVA models in 2022. Results: Fear of fat and Willpower scores were higher than Dislike scores (mean [SD]: 4.0 [2.0], 3.3 [1.7] and 1.9 [1.3], respectively). Fear of fat was higher among women, whereas Dislike and Willpower were higher among men (all P<0.0001). Obesity was associated with greater Fear of fat scores (P<0.0001, mean difference vs. normal-weight participants [95% CI]: 0.35 [0.24;0.46] in women, 0.36 [0.17;0.56] in men), lower Dislike scores (-0.38 [-0.45;-0.32] in women, -0.43 [-0.56;-0.30] in men) and lower Willpower scores (-1.00 [-0.18;-0.90] in women, -0.40 [-0.57;-0.23] in men). In both genders, lower income was associated with lower Dislike, Fear of fat and Willpower scores (all P<0.0001), and lower education with greater Fear of fat and Willpower scores (all P<0.0001).Conclusions: EWB was driven by the fear of gaining weight and the belief in weight controllability. This study provides new insights into which population subgroups should be targeted by interventions aimed at reducing EWB

Weight bias in adults from the NutriNet-Santé study: associations with weight status, socioeconomic position and demographic characteristics

International audienc

Analyse et modélisation des effets des pratiques agricoles sur les services et disservices écosystémiques dépendant des adventices. Application à l'évaluation et la conception de systèmes de culture économes en herbicides

Programme Evaluation et réduction des risques liés à l’utilisation des PesticidesAPR 2011 «Changer les pratiques agricoles pour préserver les services écosystémiques»Rapport final-août 2016This report describes the methods and results of the FLORSYS project financed by the research programme “Assessing and reducing environmental risks from plant protection products” funded by the French Ministries in charge of Ecology and Agriculture

Conception de systèmes de culture multiperformants à l'aide de modèles prédisant la nuisibilité et les services dépendant des adventices

Ce numéro comprend les articles issus du colloque de restitution Ecophyto Recherche « Des outils et des dispositifs pour éclairer les décisions, explorer les possibles et accompagner la transition vers des systèmes économes et multi-performants », qui s’est tenu à Saint-Malo, du 22 au 24 mars 2017.EASPEGESTADGEAPSIAGROSUPUBINRAWeeds may be harmful for crop production but are essential for biodiversity conservation. In this project,we analysed and modelled the biophysical processes driving the effects of cultural techniques on weedflora and the latter's impact on crop production (e.g. yield loss, field infestation) and on other bioticcomponents that are either beneficial (e.g. bees, birds) or harmful (e.g. the parasitic plant broomrape)for crop production. We developed and used tools and simulation methods to evaluate and designcropping systems that reconcile crop production, biodiversity and reduced herbicide use. Achieving ahigh performance for these three objectives was difficult though achieving it for two of them (productionand biodiversity, or production and reduced herbicide use) was feasible.Les adventices ("mauvaises herbes") peuvent être nuisibles pour la production agricole mais sontessentielles pour la biodiversité. Nous avons analysé et modélisé les processus biophysiques impliquésdans les effets des techniques culturales sur la flore adventice ainsi que l’impact des adventices sur laproduction agricole (ex. perte de rendement, « salissement » du champ) et sur les composantesbiotiques bénéfiques (ex. abeilles) et nuisibles (ex. la plante parasite orobanche rameuse) pour laproduction agricole. Nous avons développé et utilisé des outils et méthodes de simulation pour évalueret concevoir des systèmes de culture conciliant production agricole, biodiversité et réduction d'usaged'herbicide. Concilier un haut niveau de performances s'avère encore difficile pour ces trois objectifsmais faisable pour deux objectifs (production et biodiversité, ou production et réduction des herbicides)

geonetwork/geonetwork-ui: GeoNetwork-UI v2.0.1

&lt;p&gt;This release mainly contains bug fixes and minor improvements. Thanks to all contributors involved.&lt;/p&gt; &lt;h2&gt;What's Changed&lt;/h2&gt; &lt;h3&gt;Fixes &amp; improvements&lt;/h3&gt; &lt;ul&gt; &lt;li&gt;Remove technical words by @fvanderbiest in https://github.com/geonetwork/geonetwork-ui/pull/650&lt;/li&gt; &lt;li&gt;Fix favorite star tooltip translation by @fgravin in https://github.com/geonetwork/geonetwork-ui/pull/653&lt;/li&gt; &lt;li&gt;Fix CORS issues in webcomponent demo by @fgravin in https://github.com/geonetwork/geonetwork-ui/pull/655&lt;/li&gt; &lt;li&gt;Datahub: Fix display of ESRI data on map by @tkohr in https://github.com/geonetwork/geonetwork-ui/pull/652&lt;/li&gt; &lt;li&gt;Datahub: Display external viewer button correctly by @tkohr in https://github.com/geonetwork/geonetwork-ui/pull/656&lt;/li&gt; &lt;li&gt;WebComponents: Fix dropdown-selector not showing by @jahow in https://github.com/geonetwork/geonetwork-ui/pull/658&lt;/li&gt; &lt;li&gt;Datahub: Make font-sizes and colors same across the expandable panel by @Angi-Kinas in https://github.com/geonetwork/geonetwork-ui/pull/660&lt;/li&gt; &lt;li&gt;Datahub: Change font style in expandable-panel by @Angi-Kinas in https://github.com/geonetwork/geonetwork-ui/pull/662&lt;/li&gt; &lt;li&gt;Datahub: Change font-color and link style by @Angi-Kinas in https://github.com/geonetwork/geonetwork-ui/pull/664&lt;/li&gt; &lt;/ul&gt; &lt;h3&gt;Dependencies&lt;/h3&gt; &lt;ul&gt; &lt;li&gt;chore(deps-dev): bump postcss from 8.4.27 to 8.4.31 by @dependabot in https://github.com/geonetwork/geonetwork-ui/pull/646&lt;/li&gt; &lt;li&gt;chore(deps): bump @babel/traverse from 7.22.8 to 7.23.2 by @dependabot in https://github.com/geonetwork/geonetwork-ui/pull/654&lt;/li&gt; &lt;/ul&gt; &lt;p&gt;&lt;strong&gt;Full Changelog&lt;/strong&gt;: https://github.com/geonetwork/geonetwork-ui/compare/v2.0.0...v2.0.1&lt;/p&gt

geonetwork/geonetwork-ui: GeoNetwork-UI v2.0.2

&lt;p&gt;This release mainly contains bug fixes and minor improvements. Thanks to all contributors involved.&lt;/p&gt; &lt;h2&gt;What's Changed&lt;/h2&gt; &lt;h3&gt;Fixes and improvements&lt;/h3&gt; &lt;ul&gt; &lt;li&gt;Datahub: Display UpdateFrequencyCustom correctly by @jahow in https://github.com/geonetwork/geonetwork-ui/pull/683&lt;/li&gt; &lt;li&gt;Datahub: Link detection with unknown mime type by @jahow in https://github.com/geonetwork/geonetwork-ui/pull/690&lt;/li&gt; &lt;li&gt;Datahub: Fix abstract display in record preview in https://github.com/geonetwork/geonetwork-ui/pull/672&lt;/li&gt; &lt;li&gt;Datahub: Links format filter filters out everything in https://github.com/geonetwork/geonetwork-ui/pull/668&lt;/li&gt; &lt;li&gt;Datahub: Display record's update status correctly in https://github.com/geonetwork/geonetwork-ui/pull/679&lt;/li&gt; &lt;/ul&gt; &lt;p&gt;&lt;strong&gt;Full Changelog&lt;/strong&gt;: https://github.com/geonetwork/geonetwork-ui/compare/v2.0.1...v2.0.2&lt;/p&gt

geonetwork/core-geonetwork: GeoNetwork 4.2.7

&lt;p&gt;https://sourceforge.net/projects/geonetwork/files/GeoNetwork_opensource/v4.2.7/&lt;/p&gt; &lt;p&gt;GeoNetwork 4.2.7 release is a minor release.&lt;/p&gt; &lt;h1&gt;List of changes&lt;/h1&gt; &lt;p&gt;Release highlights:&lt;/p&gt; &lt;ul&gt; &lt;li&gt;&lt;a href="https://github.com/geonetwork/core-geonetwork/pull/7403"&gt;Add more db information to the site information page&lt;/a&gt;&lt;/li&gt; &lt;li&gt;&lt;a href="https://github.com/geonetwork/core-geonetwork/pull/7446"&gt;Fix cookies path when deployed on root &quot;/&quot; context&lt;/a&gt;&lt;/li&gt; &lt;li&gt;&lt;a href="https://github.com/geonetwork/core-geonetwork/pull/7501"&gt;Security / Jolokia update&lt;/a&gt;&lt;/li&gt; &lt;/ul&gt; &lt;p&gt;and more ... see &lt;a href="https://github.com/geonetwork/core-geonetwork/issues?q=is%3Aissue+milestone%3A4.2.6+is%3Aclosed"&gt;4.2.7 issues&lt;/a&gt; and &lt;a href="https://github.com/geonetwork/core-geonetwork/pulls?page=3&amp;q=is%3Apr+milestone%3A4.2.7+is%3Aclosed"&gt;pull requests&lt;/a&gt; for full details.&lt;/p&gt