Solar PV Lighting and Studying after Sunset: Analysis of Micro-benefits in Off-grid Rural Ghana

Solar PV light provides school children living in off-grid rural communities the opportunity to have clean and bright lighting to study after sunset. On the contrary, lighting provided from poor sources can pollute and adversely affect human eyes during reading and writing. Using indicator-based questionnaires in cross-sectional surveys, households with and without solar PV lighting were surveyed in off-grid rural communities in Ghana. The study investigated lighting and children’s studies after sunset. The results indicated that whereas solar PV light of 5-20 watts dc lamps was sufficient for 5-6 children to study together, lighting from kerosene lantern could be sufficient for 1-3 children. All things being equal, the results showed that children who use solar PV light to study upto 2 hours after sunset are likely to improve on their examination results. The extent to which solar PV lighting significantly impacts on studying after sunset was established using some identified indicators. Knowledge of the results provides understanding of the relative constraints in lighting services faced by children in rural communities without access to quality lighting. Such micro-level data will help to enhance policy and planning efforts to increase access to clean and renewable energy-based lighting devices to achieve efficient visual comfort in off-grid rural communities

ARTICLE REVIEW :THE ROLE OF URBAN MARKETING IN LOCAL ECONOMIC DEVELOPMENT A POLITICAL ECONOMIC PERSPECTIVE

The aggressive marketing of cities to attract private finance and capital is one important aspect of municipal neoliberalism. Urban marketing, as it is called, is said to be the the surest way to deliver urban economic development. Using a political-economic framework, this paper provides an alternative analysis of urban marketing, and highlights other avenues for addressing the urban question.Political Economy, Cities, Markets, Economic Development

Part 1 New SME curricula

We began our work at the first residential meeting in Accra (January 2010) by discussing the nature of SMEs (small and medium-sized enterprises) and entrepreneurship in a Ghanaian context, clarifying our understanding of the informal sector, and identifying priority areas for curriculum development. At an early stage, we recognised that there was a need to develop more appropriate courses to support enterprise education within our universities and also entrepreneurial learning beyond the campus, particularly in relation to the informal sector. This work informed the first phase, in which we began to engage with SMEs and their associations and to establish their various requirements through dialogue and knowledge sharing. This information was brought back to the second residential meeting in Kumasi (July 2010) as the basis for designing new types of provision. At Kumasi, we worked on two projects that are reported in more detail in the following sections: ♦ A problem-based design for the informal sector: the Sokoban Wood Village Project (Section 1.2) ♦ Strategies for curriculum review and course design in Ghanaian universities (Section 1.3

TRANSFORMING THIRD WORLD CITIES THROUGH GOOD URBAN GOVERNANCE: FRESH EVIDENCE

Many Ghanaians believe that introducing multi-party elections at the metropolitan, municipal and district levels would ensure the election of competent people to manage the urban or local economy. This belief is premised on the assumption that electorates are informed and would vote for competent politicians. Using the 2008 elections in Ghana, it is argued that only a minority of electorates vote on issues; the majority vote along tribal and party lines; and based on how “humble” a politician is or simply based on monetocracy. This means that introducing elections into the local government system would not necessarily lead to a transformation of the local or urban economy; greater local democracy is not the answer to the housing problem, sanitation crisis, unemployment burden and the poverty challenge. There may be the need for a new form of local democracy.Democracy, Urban, Governance, Ghana, Elections

African Immigrant Families' Views on English as a Second Language (ESL) Classes Held for Newly Arrived Immigrant Children in the United States Elementary and Middle Schools: A Study in Ethnography

This article is published with the permission of the authors.Twenty immigrant families from different Anglophone, Francophone, and Lusophone African countries were interviewed about their views on English as a Second Language (ESL) classes offered by the school systems in the United States to newly arrived immigrant children. Whereas nine families (mostly from Francophone and Lusophone Africa) found the ESL classes useful, eleven families (mostly from Anglophone Africa) found them to be useless because they did not help to improve their children's English. Some respondents were frustrated because ofthe criterion used in selecting students to participate in the program, and also because their children were kept in the program long after their English proficiency had improved. Most respondents saw inclusion within the mainstream classes, instead of separate ESL classes, as a better way to increase students' English competency.This material is the copyright of the authors. Please contact them for information about reproduction or reuse

Crash Risk Reduction at Signalized Intersections Using Longitudinal Data

This study extends the previous work of Burkey and Obeng (2004) that examined the impact of red light cameras on the type and severity of crashes at signalized intersections in Greensboro, NC. The extension takes the following form. First, we extend the data to cover 57 months, and to include demographics, technology variables, the condition of a driver at the time of the crash, vehicle characteristics, land use and visual obstruction. Second, instead of examining the impact of red light cameras, we focus on identifying the determinants of crash severity, two-vehicle crashes, and property damage costs. The major findings are that the safety impacts of seatbelt use outweigh the impacts of airbags deploying because the latter tends to increase evident injuries and property damage costs, while the former reduces these injuries. We also find that head-on collisions and under rides increase evident injuries. For two-vehicle crashes, we find that the risk of severe injuries increases in pickup-pickup crashes and SUV-pickup crashes, while the risk of possible injuries increases in car-truck crashes. For property damage costs, we found the condition of the driver at the time of the crash (i.e., illness, impaired, medical condition, driver falling asleep, driver apparently normal) to be important determinants in increasing these costs. The types of accidents that we found to increase property damage costs are running into a fixed object and under rides. Finally, we found that property damage costs of crashes are low where the land uses are commercial and institutional suggesting that the accidents that occur in these areas are minor.longitudinal data; accidents; intersections

Solar PV rural electrification and energy-poverty: A review and conceptual framework with reference to Ghana

In spite of the intention of governments to increase the use of renewable energy in electricity supply, particularly the use of solar photovoltaic (PV) for energy poverty reduction in rural and peri-urban areas of Africa, there is relatively little information on how solar PV electrification impacts on energy poverty reduction. Therefore, there is a gap in the literature and hence the need for continuous research. Using Ghana as a reference country, the historical trend, donor cooperation and other aspects of solar PV rural electrification are discussed . The paper illustrates the intersectoral linkages of solar PV electrification and indicators on education, health, information acquisition, agriculture and micro-enterprises. It also reviews sustainability related issues including costs and market barriers, subsidies, stakeholders involvement, political and policy implications, which are critical factors for sustainable market development of solar PV and other renewables. Finally, a common framework is developed to provide a basic understanding of how solar PV electrification impacts on energy-poverty. This framework provides a structure of the interrelated concepts and principles relevant to the issues under review.Rural electrification; solar PV electrification; energy-poverty; renewable energy; economic development; Ghana; Africa

Dissecting apoptosis the omics way

A combined analysis of transcription, translation and protein degradation reveals the global effects of an anticancer drug on tumour cells

Design, Synthesis, and Biological Screening of Selective Mu Opioid Receptor Ligands as Potential Treatments for Opioid Addiction

Today, more Americans die each year because of drug overdoses than are killed in motor vehicle accidents. In fact, in 2015, more than 33,000 individuals died due to an overdose of heroin or prescription opioids. Sadly, 40-60 % of patients on current opioid addiction treatment medications relapse. Studies have shown that the addiction/abuse liability of opioids are abolished in mu opioid receptor (MOR) knock-out mice; this indicates that the addiction and abuse liability of opioids are mainly mediated through MOR. Utilizing the “message-address concept”, the our laboratory reported a novel non-peptide, reversible MOR selective ligand 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α (isoquinoline-3-carboxamido)morphinan (NAQ). Molecular modeling and mutagenesis studies revealed that the selectivity of NAQ for MOR is because of the π-π stacking of the isoquinoline ring of NAQ with W318. Therefore, other heterocyclic ring systems were explored to obtain a diverse library of compounds with similar or different molecular interactions and pharmacologic characteristics as NAQ. The newly designed compounds were indole analogs of 6α/β-naltrexamine. The compounds were synthesized and the affinity and selectivity for MOR determined using the radioligand binding assay while the functional activity at MOR was determined using the [35S]GTPγS binding assay. The indole analog of 6α-naltrexamine substituted at position 7 (compound 6) was found to be very potent and had the lowest efficacy in the [35S]GTPγS functional assay while the indole analog of 6β-naltrexamine substituted at position 2 (compound 10) was identified as a MOR agonist and had the greatest efficacy. In vivo studies were conducted using the warm-water immersion assay to find whether the synthesized compounds had antinociceptive effects and/or blocked the antinociceptive effects of morphine. Not surprisingly, compound 10 was identified as an opioid agonist while compound 6 almost completely blocked morphine’s antinociceptive effects. The opioid antagonist effect of compound 6 was found to be dose dependent with an AD50 of 2.39 mg/kg (0.46-12.47). An opioid withdrawal assay was conducted on compound 6 using morphine-pelleted mice. Compound 6 produced significantly less withdrawal symptoms at 50 mg/kg than naltrexone at 1 mg/kg. Therefore, compound 6 has the potential to be used in opioid addiction and withdrawal treatment