The Condyloma acuminata - the review of the treatment methods

Introduction and purpose: Condyloma acuminata, a benign manifestation of HPV infection, is a common sexually transmitted disease. Condyloma acuminata most commonly affects the anogenital area, but can also occur in the oral cavity. Macroscopically the lesions present as raised, fleshy papules, sometimes flat and broad, pedicled or cauliflower-like. Generally, the lesions are multiple, and as they grow, tend to coalesce into larger ones. Due to the lack of symptoms, condyloma acuminata are often found incidentally during routine medical appointments, e.g. in gynecologist’s offices. Additional symptoms and signs are pain, minor bleeding and pruritus. Patients suffering from condyloma acuminata are often in psychological and psychosexual distress.  This work aims to provide a summary of the currently available treatment options based on scientific reports to date. A brief description of the state of knowledge: Among the factors that increase the risk of the HPV infection are age, lifestyle, promiscuity, smoking, HIV infection, a history of chlamydia or gonorrhea infections. To date, no treatment algorithm has been developed for condyloma acuminata. Two vaccines are on offer as primary prevention, Gardasil and Cervarix. The available treatment options are divided into two main groups: patient-administered and physician administered. Surgical methods have the highest therapeutic efficacy. Condyloma acuminata has a high recurrence rate. Usually, a multi-session combination treatment is needed to reach total remission. Summary (conclusions): The treatment of condyloma acuminata includes personalized targets due to their diverse clinical picture and the limitations of certain patient groups. The available treatment options do not exhaust the needs of patients suffering from condyloma acuminata. Further research into the effectiveness of specific treatments is advisable

Critical Analysis of the Efficacy and Limitations of GLP-1 Pharmaceuticals in Obesity Management: A Comprehensive Literature Review

Introduction and purpose Obesity, a pervasive global pandemic intricately linked to various comorbidities, necessitates a comprehensive and nuanced approach. This article delves into the intricate realm of obesity guidelines, underscoring the significance of lifestyle modifications, preventive measures for childhood obesity, population-based strategies, clinical management protocols, and vigilant monitoring. GLP-1 drugs, originally designed for type 2 diabetes management, exhibit multifaceted effects beyond glycemic control. They influence appetite regulation, gastric emptying dynamics, and potentially contribute to cardiovascular health improvements. However, the commendable effects come with a caveat - potential side effects necessitating careful consideration in clinical decision-making. Despite gaining popularity through celebrity endorsements, this article firmly underscores the need to view GLP-1 pharmacotherapy as a recommended intervention rather than a miraculous solution. A brief description of the state of knowledge Integral to the obesity discourse is the imperative to address weight stigma, demanding evidence-based approaches in both clinical and public health domains. The narrative extends into the future landscape of obesity pharmacotherapy, contemplating the potential role of probiotics. Emphasizing the necessity for long-term studies and randomized trials, it positions probiotics as a low-risk alternative with significant potential in mitigating obesity while simultaneously addressing concerns related to antibiotic resistance. Summary The pursuit of a balanced and effective approach to obesity management necessitates a nuanced understanding of medical interventions, consideration of societal perceptions, and exploration of innovative possibilities within the evolving landscape of healthcare

Alokacja i redystrybucja zasobów mieszkaniowych w Polsce w kontekście koncepcji sprawiedliwości społecznej (Rowlsa i Dworkina)

Artykuł koncentruje się na sprawiedliwości społecznej w kontekście lokacji i redystrybucji zasobów mieszkaniowych w Polsce, ze szczególnym uwzględnieniem zasobów społecznych. Uwzględniono zachodzące zmiany, wpływające na zwiększenie sprawiedliwości społecznej, rozumianej zgodnie z koncepcją sprawiedliwości dystrybutywnej J. Rawlsa (1971). Celem artykułu jest odpowiedź na pytanie, czy koncepcja sprawiedliwości społecznej (mającej umocowanie w Konstytucji RP) ma wpływ na realizowaną politykę mieszkaniową? Jeśli tak, to w jaki sposób realizowana jest sprawiedliwość pozioma i pionowa w obliczu zmian i reform programów mieszkaniowych? Analiza koncepcji sprawiedliwości społecznej w polityce mieszkaniowej obejmuje okres od roku 2006, kiedy to powołano program wspierający zakup pierwszego mieszkania „Rodzina na swoim”, do roku 2019 i programu Mieszkanie Plus

Alokacja i redystrybucja zasobów mieszkaniowych w Polsce w kontekście koncepcji sprawiedliwości społecznej (Rowlsa i Dworkina)

The article concentrates on social justice in the context of housing allocation and redistribution in Poland, especially the stock of social housing. Consideration is given to the changes currently taking place, which are leading to an increase in social justice, understood in accordance with John Rawls’ concept of distributive justice. The aim of the article is to answer the question of whether the concept of social justice (which is anchored in the Constitution of the Republic of Poland) has an impact on the implemented housing policy. If so, how is horizontal and vertical equity realised in the face of changes and reforms in housing programmes? The analysis of the concept of social justice in housing policy covers the period from 2006, when the programme supporting the purchase of the first flat ‘Rodzina na swoim’ was established, to 2019 and the programme ‘Mieszkanie Plus.’Artykuł koncentruje się na sprawiedliwości społecznej w kontekście lokacji i redystrybucji zasobów mieszkaniowych w Polsce, ze szczególnym uwzględnieniem zasobów społecznych. Uwzględniono zachodzące zmiany, wpływające na zwiększenie sprawiedliwości społecznej, rozumianej zgodnie z koncepcją sprawiedliwości dystrybutywnej J. Rawlsa (1971). Celem artykułu jest odpowiedź na pytanie, czy koncepcja sprawiedliwości społecznej (mającej umocowanie w Konstytucji RP) ma wpływ na realizowaną politykę mieszkaniową? Jeśli tak, to w jaki sposób realizowana jest sprawiedliwość pozioma i pionowa w obliczu zmian i reform programów mieszkaniowych? Analiza koncepcji sprawiedliwości społecznej w polityce mieszkaniowej obejmuje okres od roku 2006, kiedy to powołano program wspierający zakup pierwszego mieszkania „Rodzina na swoim”, do roku 2019 i programu Mieszkanie Plus

Factors influencing the length of the recovery period after blepharoplasty: a review of the latest data

Introduction and purpose Blepharoplasty is a surgical procedure aimed at restoring the functionality and/or aesthetics of the eyelids. The aim of the study is to draw attention to the factors influencing the recovery period at successive stages of therapeutic procedures. A brief description of the state of knowledge: Preoperative consultation is important in selecting patients, planning surgical procedures, identifying potential complications and meeting patients' expectations. In patients with hypertension, diabetes, smoking, and anticoagulant treatment, a worse scar assessment, longer recovery period and more complications have been observed. Patients who have undergone refractive surgery within the last 6 months are not suitable candidates for blepharoplasty. Nutrition status has a significant impact on wound healing and tissue repair after aesthetic medicine procedures. The use of continuous sutures compared to tissue glue results in similar wound healing time and postoperative discomfort level. Postoperative wound care is essential for the healing process. Electrostimulation of the wound does not accelerate edema reduction. We have focused on many complications, such as swelling, bleeding, infections, eyelid malposition, dry eye syndrome, wound dehiscence, ways to cope with these problems, and the role of lasers.  Summary (conclusions): Important is the proper preparation of the patient for the procedure. A detailed interview and examination influence therapeutic decisions, allowing the doctor to choose the most optimal treatment methods that will shorten the recovery time. Blepharoplasty is one of the most commonly performed aesthetic procedures, so we propose the development of publicly accessible standards that should be included in the initial interview