Twisted Vortices in a Gauge Field Theory

We inspect a particular gauge field theory model that describes the properties of a variety of physical systems, including a charge neutral two-component plasma, a Gross-Pitaevskii functional of two charged Cooper pair condensates, and a limiting case of the bosonic sector in the Salam-Weinberg model. It has been argued that this field theory model also admits stable knot-like solitons. Here we produce numerical evidence in support for the existence of these solitons, by considering stable axis-symmetric solutions that can be thought of as straight twisted vortex lines clamped at the two ends. We compute the energy of these solutions as a function of the amount of twist per unit length. The result can be described in terms of a energy spectral function. We find that this spectral function acquires a minimum which corresponds to a nontrivial twist per unit length, strongly suggesting that the model indeed supports stable toroidal solitons.Comment: 10 pages, 5 figures, title changed, minor revisions, and more references adde

Mott Transition in An Anyon Gas

We introduce and analyze a lattice model of anyons in a periodic potential and an external magnetic field which exhibits a transition from a Mott insulator to a quantum Hall fluid. The transition is characterized by the anyon statistics, $\alpha$, which can vary between Fermions, $\alpha=0$, and Bosons, $\alpha=1$. For bosons the transition is in the universality class of the classical three-dimensional XY model. Near the Fermion limit, the transition is described by a massless $2+1$ Dirac theory coupled to a Chern-Simons gauge field. Analytic calculations perturbative in $\alpha$, and also a large N-expansion, show that due to gauge fluctuations, the critical properties of the transition are dependent on the anyon statistics. Comparison with previous calcualations at and near the Boson limit, strongly suggest that our lattice model exhibits a fixed line of critical points, with universal critical properties which vary continuosly and monotonically as one passes from Fermions to Bosons. Possible relevance to experiments on the transitions between plateaus in the fractional quantum Hall effect and the magnetic field-tuned superconductor-insulator transition are briefly discussed.Comment: text and figures in Latex, 41 pages, UBCTP-92-28, CTP\#215

Thermodynamics of an Anyon System

We examine the thermal behavior of a relativistic anyon system, dynamically realized by coupling a charged massive spin-1 field to a Chern-Simons gauge field. We calculate the free energy (to the next leading order), from which all thermodynamic quantities can be determined. As examples, the dependence of particle density on the anyon statistics and the anyon anti-anyon interference in the ideal gas are exhibited. We also calculate two and three-point correlation functions, and uncover certain physical features of the system in thermal equilibrium.Comment: 18 pages; in latex; to be published in Phys. Rev.

New insights into the genetic etiology of Alzheimer's disease and related dementias

Characterization of the genetic landscape of Alzheimer's disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/'proxy' AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis. Pathway enrichment analyses confirmed the involvement of amyloid/tau pathways and highlighted microglia implication. Gene prioritization in the new loci identified 31 genes that were suggestive of new genetically associated processes, including the tumor necrosis factor alpha pathway through the linear ubiquitin chain assembly complex. We also built a new genetic risk score associated with the risk of future AD/dementia or progression from mild cognitive impairment to AD/dementia. The improvement in prediction led to a 1.6- to 1.9-fold increase in AD risk from the lowest to the highest decile, in addition to effects of age and the APOE ε4 allele

Euclid: fast two-point correlation function covariance through linear construction

Galaxie

KiDS and Euclid: Cosmological implications of a pseudo angular power spectrum analysis of KiDS-1000 cosmic shear tomography

Large scale structure and cosmolog

Euclid preparation: XVII. Cosmic dawn survey: Spitzer space telescope observations of the Euclid deep fields and calibration fields

Galaxie

Euclid preparation. XV. Forecasting cosmological constraints for the Euclid and CMB joint analysis

Galaxie