Reformulating the empowerment process through women entrepreneurship in a collective context.

The purpose of this study is to develop an empirically informed framework to analyze women empowerment and entrepreneurship, contextualized within a collective society. The authors conducted 15 in-depth semi-structured interviews with women entrepreneurs located in the United Arab Emirates to understand their entrepreneurial experiences and how they were empowered. Findings suggest that the three aspects of power characterized as "positive" from within Rowlands' distinctions ("power to", "power with" and "power within") dominate, as opposed to those emphasized in the literature ("power to" and "power over"). Findings include empowerment of the "me" (individual) also synergistically contributes to empowerment of the "we" (society), when considering empowerment within a collective society. A psychology model was used as a basis to develop a Collective Empowerment Process Framework. This framework provides a fresh look at empowerment, allowing for explanations of how women in specific contexts experience empowerment and social change

Hegemonic conceptualizations of empowerment in entrepreneurship and their suitability for collective contexts.

The relationship between empowerment and entrepreneurship in collective societies is, in our view, insufficiently examined. Accepted definitions of empowerment and the assumptions underlying programs and research designs based on them result in outcomes that self-fulfil and, as a result, disappoint. Several issues are prevalent: the empowerment potential of programs is overestimated and the dominant view of what constitutes an 'empowered self' does not go deep enough to explore, and reframe, the self and its relationship to agency—two issues at the core of empowerment definitions and formulations. In this conceptual article, we examine the entrepreneurship and empowerment literature to suggest ways forward for the future health and relevance of the subject area. We highlight a serious methodological and perceptual issue within the literature, which offers many opportunities for theory development in the field

The role of strong ties in empowering women entrepreneurs in collectivist contexts.

This study examines what social ties within collectivist settings mean for women's venturing and how these ties support women in gaining empowerment through their ventures. Thirteen in-depth semi-structured interviews with women entrepreneurs located in the United Arab Emirates (UAE) were conducted to examine the influence of social ties in their ventures. The findings reveal that women in this context, contrary to most reported findings in the extant literature, both rely more on and find strong ties more conducive than weak ties in most of their entrepreneurial behaviours and activities. Results also show how the UAE's collectivist cultural norms shape social networks and inform individual decision-making, resource acquisition, well-being and self-efficacy as well as enhance women's empowerment through entrepreneurship. The women entrepreneurs were found to leverage their social ties for both power and action throughout their entrepreneurial journey consistent with their culture. A conceptual model, derived from the results of a qualitative study, illustrating the relationships between women entrepreneurs' use of social ties and the empowering capacities of venturing within a collectivist cultural context is developed. Based on these findings, the authors discuss the implications for policymakers and recommend avenues for future research, and research designs, on women entrepreneurs in collectivist contexts

Lebanon: Technica International - SDG#5 gender equality and women's empowerment

Gender equality and women's empowerment are key priorities to achieve sustainability in the world, particularly in the Middle East and North Africa (MENA) region where women are often an under-represented group across politics, economic and social spheres. According to a recent publication by the World Economic Forum, it would take 115 years for the region to reach gender parity. The region has one of the lowest participation rates for women in the workforce, and the number has been in decline since 2020. The family business is the most common form of enterprise in this region, and research perceives that female family members are more likely to participate, either directly or indirectly, in the running of these companies, though they are less likely to become the heir. Family businesses play an important role in promoting gender equality and women's advancement in their organisations, and they can serve as valuable examples for other companies and institutions to emulate. The present case is set in Lebanon and illustrates how a long-standing multinational Lebanese family business, TI, seeks to improve gender equality and women's empowerment within its business. The case first highlights the active involvement of the daughter of the founder, Cynthia Abou Khater, who joined the business in 2007 and who is currently Vice President overseeing Strategy, Information Technology and Human Resource departments. Cynthia was actively instrumental in attracting more female talent to the company and in developing an organisational environment that is conducive for women. The present case focuses on the efforts of TI to promote gender equality in the organisation, and it examines the initiatives and practices adopted by the company to achieve this goal

Women's empowerment as an outcome of NGO projects: is the current approach sustainable?

The area of women's empowerment has attracted increasing attention among a wide range of interest groups, from authors to researchers to feminist scholars and non-governmental organizations (NGOs). This paper aims to identify the diverse understandings of women's empowerment in the literature and to discuss empirical evidence from NGO projects in the field. A systematic literature review is employed that includes an analysis of relevant high-quality articles and research papers published in the Scopus database, as well as those produced by United Nations (UN) bodies and well-published authors. The findings highlighted four common understandings of women's empowerment including granting women a voice, challenging existing power structures, the radical transformation of lives and livelihoods, and gender mainstreaming. The findings of these empirical studies on the role of NGOs in this field revealed understandings limited to granting women a voice and gender mainstreaming, thus reflecting the fact that limited knowledge of women's empowerment hampers the ability of NGOs to serve women's advancement and sustainable development. Further-more, and given that these approaches and understandings still fall short of achieving social inclusion for women, it is recommended that these NGOs discharge their efforts toward initiating systemic change to actually sustain female empowerment in the communities in which they are active

Matriptase activation of gq drives epithelial disruption and inflammation via RSK and DUOX

Epithelial tissues are primed to respond to insults by activating epithelial cell motility and rapid inflammation. Such responses are also elicited upon overexpression of the membrane-bound protease, Matriptase, or mutation of its inhibitor, Hai1. Unrestricted Matriptase activity also predisposes to carcinoma. How Matriptase leads to these cellular outcomes is unknown. We demonstrate that zebrafish hai1a mutants show increased H2O2, NfκB signalling, and IP3R -mediated calcium flashes, and that these promote inflammation, but do not generate epithelial cell motility. In contrast, inhibition of the Gq subunit in hai1a mutants rescues both the inflammation and epithelial phenotypes, with the latter recapitulated by the DAG analogue, PMA. We demonstrate that hai1a has elevated MAPK pathway activity, inhibition of which rescues the epidermal defects. Finally, we identify RSK kinases as MAPK targets disrupting adherens junctions in hai1a mutants. Our work maps novel signalling cascades mediating the potent effects of Matriptase on epithelia, with implications for tissue damage response and carcinoma progression

Cone-Rod Dystrophy Due to Mutations in a Novel Photoreceptor-Specific Homeobox Gene (CRX) Essential for Maintenance of the Photoreceptor

Genes associated with inherited retinal degeneration have been found to encode proteins required for phototransduction, metabolism, or structural support of photoreceptors. Here we show that mutations in a novel photoreceptor-specific homeodomain transcription factor gene (CRX) cause an autosomal dominant form of cone-rod dystrophy (adCRD) at the CORD2 locus on chromosome 19q13. In affected members of a CORD2-linked family, the highly conserved glutamic acid at the first position of the recognition helix is replaced by alanine (E80A). In another CRD family, a 1 bp deletion (E168 [delta1 bp]) within a novel sequence, the WSP motif, predicts truncation of the C-terminal 132 residues of CRX. Mutations in the CRX gene cause adCRD either by haploinsufficiency or by a dominant negative effect and demonstrate that CRX is essential for the maintenance of mammalian photoreceptorsThis work was supported by the RP Foundation of Canada (R. R. M.), the Foundation Fighting Blindness (R. R. M. and S. G. J.), the Canadian Genetic Disease Network (R. R. M. and A. D.), the Medical Research Council of Canada (R. R. M.), The Wellcome Trust (043825/Z/95) and the Human Genome Mapping Resource Centre (C. Y. G.-E. and S. S. B.), the Howard Hughes Medical Institute and NIH R01 EY0 8064 (C. L. C.), the Canadian Genome Analysis and Technology Genome Resource Facility (S. W. S. and L.-C. T.), the NIH/NEI (EY05627) (S. G. J.), and the Greek National Scholarship Foundation (M. P.). R. R. M. and L.-C. T. are International Research Scholars of the Howard Hughes Medical Institute

The care of older cancer patients in the United Kingdom

The ageing population poses new challenges globally. Cancer care for older patients is one of these challenges, and it has a significant impact on societies. In the United Kingdom (UK), as the number of older cancer patients increases, the management of this group has become part of daily practice for most oncology teams in every geographical area. Older cancer patients are at a higher risk of both under- and over-treatment. Therefore, the assessment of a patient’s biological age and effective organ functional reserve becomes paramount. This may then guide treatment decisions by better estimating a prognosis and the risk-to-benefit ratio of a given therapy to anticipate and mitigate against potential toxicities/difficulties. Moreover, older cancer patients are often affected by geriatric syndromes and other issues that impact their overall health, function and quality of life. Comprehensive geriatric assessments offer an opportunity to identify and address health problems which may then optimise one’s fitness and well-being. Whilst it is widely accepted that older cancer patients may benefit from such an approach, resources are often scarce, and access to dedicated services and research remains limited to specific centres across the UK. The aim of this project is to map the current services and projects in the UK to learn from each other and shape the future direction of care of older patients with cancer

Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial

Background Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy. Brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases (such as cerebral microbleeds) are associated with greater risks of recurrent intracerebral haemorrhage. We did subgroup analyses of the RESTART trial to explore whether these brain imaging features modify the effects of antiplatelet therapy